p53 acetylation is crucial for its transcription-independent proapoptotic functions

Journal of Biological Chemistry

Volumn 284, Issue 17, 2009, Pages 11171-11183

  Yamaguchi, Hirohito ^a   Woods, Nicholas T ^c   Piluso, Landon G ^d   Lee, Heng Huan ^a   Chen, Jiandong ^c   Bhalla, Kapil N ^e   Monteiro, Alvaro ^c   Liu, Xuan ^d   Hung, Mien Chie ^a   Wang, Hong Gang ^b,f  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BAX ACTIVATION; CANCER CELLS; CARBOXYL-TERMINAL; CELL-CYCLE ARREST; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACIDS; INDEPENDENT FUNCTIONS; KNOCK OUTS; LYSINE RESIDUES; NEW MECHANISMS; PRO-APOPTOTIC FUNCTION; REACTIVE OXYGEN SPECIES; TRANSACTIVATION; TRANSCRIPTIONAL ACTIVITY;

ACETYLATION; AMINO ACIDS; ORGANIC ACIDS; OXYGEN; TRANSCRIPTION;

CELL DEATH;

4 [N (2 HYDROXYETHYL) N [2 (3 INDOLYL)ETHYL]AMINOMETHYL]CINNAMOHYDROXAMIC ACID; KU ANTIGEN; LYSINE; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; VORINOSTAT; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; GLUTATHIONE TRANSFERASE; HISTONE DEACETYLASE; TP53 PROTEIN, HUMAN;

ACETYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG RESPONSE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; BIOSYNTHESIS; CELL CYCLE; CELL FRACTIONATION; CELL STRAIN K 562; CHEMISTRY; GENE EXPRESSION REGULATION; METABOLISM; PROTEIN TERTIARY STRUCTURE; TRANSCRIPTION INITIATION;

ANTIGENS, NUCLEAR; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE TRANSFERASE; HISTONE DEACETYLASES; HUMANS; K562 CELLS; LYSINE; PROTEIN STRUCTURE, TERTIARY; SUBCELLULAR FRACTIONS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 66449099052     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809268200     Document Type: Article

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