-
1
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima T, Richardson P, Chauhan D, et al. 2001. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 61(7):3071-76
-
(2001)
Cancer Res.
, vol.61
, Issue.7
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
-
2
-
-
18544367201
-
NF-kappa B as a therapeutic target in multiple myeloma
-
Hideshima T, Chauhan D, Richardson P, et al. 2002. NF-kappa B as a therapeutic target in multiple myeloma. J. Biol. Chem. 277(19):16639-47
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.19
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
-
3
-
-
0346122900
-
Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
-
Hideshima T, Chauhan D, Hayashi T, et al. 2003. Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma. Oncogene 22(52):8386-93
-
(2003)
Oncogene
, vol.22
, Issue.52
, pp. 8386-8393
-
-
Hideshima, T.1
Chauhan, D.2
Hayashi, T.3
-
4
-
-
0037441760
-
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
-
Hideshima T, Mitsiades C, Akiyama M, et al. 2003. Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341. Blood 101(4):1530-34
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1530-1534
-
-
Hideshima, T.1
Mitsiades, C.2
Akiyama, M.3
-
5
-
-
0242496212
-
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
-
Mitsiades N, Mitsiades CS, Poulaki V, et al. 2002. Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc. Natl. Acad. Sci. USA 99(22):14374-79
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.22
, pp. 14374-14379
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
-
6
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
-
Mitsiades N, Mitsiades CS, Richardson PG, et al. 2003. The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101(6):2377-80
-
(2003)
Blood
, vol.101
, Issue.6
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
-
7
-
-
0036023407
-
A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies
-
Aghajanian C, Soignet S, Dizon DS, et al. 2002. A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin. Cancer Res. 8(8):2505-11
-
(2002)
Clin. Cancer Res.
, vol.8
, Issue.8
, pp. 2505-2511
-
-
Aghajanian, C.1
Soignet, S.2
Dizon, D.S.3
-
8
-
-
5644250621
-
A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
-
Jagannath S, Barlogie B, Berenson J, et al. 2004. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br. J. Haematol. 127(2):165-72
-
(2004)
Br. J. Haematol.
, vol.127
, Issue.2
, pp. 165-172
-
-
Jagannath, S.1
Barlogie, B.2
Berenson, J.3
-
9
-
-
0037111832
-
Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
-
Orlowski RZ, Stinchcombe TE, Mitchell BS, et al. 2002. Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J. Clin. Oncol. 20(22):4420-27
-
(2002)
J. Clin. Oncol.
, vol.20
, Issue.22
, pp. 4420-4427
-
-
Orlowski, R.Z.1
Stinchcombe, T.E.2
Mitchell, B.S.3
-
10
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson PG, Barlogie B, Berenson J, et al. 2003. A phase 2 study of bortezomib in relapsed, refractory myeloma. N. Engl. J. Med. 348(26):2609-17
-
(2003)
N. Engl. J. Med.
, vol.348
, Issue.26
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
-
11
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams J, Palombella VJ, Sausville EA, et al. 1999. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. 59(11):2615-22
-
(1999)
Cancer Res.
, vol.59
, Issue.11
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
-
12
-
-
0037342895
-
Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines
-
Ling YH, Liebes L, Jiang JD, et al. 2003. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines. Clin. Cancer Res. 9(3):1145-54
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.3
, pp. 1145-1154
-
-
Ling, Y.H.1
Liebes, L.2
Jiang, J.D.3
-
13
-
-
0038206722
-
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
-
Pham LV, Tamayo AT, Yoshimura LC, et al. 2003. Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J. Immunol. 171(1):88-95
-
(2003)
J. Immunol.
, vol.171
, Issue.1
, pp. 88-95
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
-
14
-
-
0032885416
-
The proteasome inhibitor PS-341 in cancer therapy
-
Teicher BA, Ara G, Herbst R, et al. 1999. The proteasome inhibitor PS-341 in cancer therapy. Clin. Cancer Res. 5(9):2638-45
-
(1999)
Clin. Cancer Res.
, vol.5
, Issue.9
, pp. 2638-2645
-
-
Teicher, B.A.1
Ara, G.2
Herbst, R.3
-
15
-
-
0035328584
-
Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-kappaB inhibition
-
Cusack JC Jr., Liu R, Houston M, et al. 2001. Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res. 61(9):3535-40
-
(2001)
Cancer Res.
, vol.61
, Issue.9
, pp. 3535-3540
-
-
Cusack Jr., J.C.1
Liu, R.2
Houston, M.3
-
16
-
-
0037342894
-
The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
-
Ma MH, Yang HH, Parker K, et al. 2003. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin. Cancer Res. 9(3):1136-44
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.3
, pp. 1136-1144
-
-
Ma, M.H.1
Yang, H.H.2
Parker, K.3
-
17
-
-
1542348477
-
Cancer statistics, 2004
-
Jemal A, Tiwari RC, Murray T, et al. 2004. Cancer statistics, 2004. CA Cancer J. Clin. 54(1):8-29
-
(2004)
CA Cancer J. Clin.
, vol.54
, Issue.1
, pp. 8-29
-
-
Jemal, A.1
Tiwari, R.C.2
Murray, T.3
-
18
-
-
0347815503
-
Single versus double autologous stem-cell transplantation for multiple myeloma
-
Attal M, Harousseau JL, Facon T, et al. 2003. Single versus double autologous stem-cell transplantation for multiple myeloma. N. Engl. J. Med. 349(26):2495-2502
-
(2003)
N. Engl. J. Med.
, vol.349
, Issue.26
, pp. 2495-2502
-
-
Attal, M.1
Harousseau, J.L.2
Facon, T.3
-
19
-
-
0037739753
-
High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
-
Child JA, Morgan GJ, Davies FE, et al. 2003. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N. Engl. J. Med. 348(19):1875-83
-
(2003)
N. Engl. J. Med.
, vol.348
, Issue.19
, pp. 1875-1883
-
-
Child, J.A.1
Morgan, G.J.2
Davies, F.E.3
-
20
-
-
0037443390
-
Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: A prospective randomized phase 3 study
-
Segeren CM, Sonneveld P, van der HB, et al. 2003. Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study. Blood 101(6):2144-51
-
(2003)
Blood
, vol.101
, Issue.6
, pp. 2144-2151
-
-
Segeren, C.M.1
Sonneveld, P.2
Van Der, H.B.3
-
21
-
-
3042775299
-
Clinical course of patients with relapsed multiple myeloma
-
Kumar SK, Therneau TM, Gertz MA, et al. 2004. Clinical course of patients with relapsed multiple myeloma. Mayo Clin. Proc. 79(7):867-74
-
(2004)
Mayo Clin. Proc.
, vol.79
, Issue.7
, pp. 867-874
-
-
Kumar, S.K.1
Therneau, T.M.2
Gertz, M.A.3
-
22
-
-
8944220233
-
A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
-
Intergroupe Francais du Myelome
-
Attal M, Harousseau J-L, Stoppa A-M, et al. 1996. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N. Engl. J. Med. 335(2):91-97
-
(1996)
N. Engl. J. Med.
, vol.335
, Issue.2
, pp. 91-97
-
-
Attal, M.1
Harousseau, J.-L.2
Stoppa, A.-M.3
-
23
-
-
0027164309
-
Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma
-
Greipp PR, Lust JA, O'Fallon WM, et al. 1993. Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma. Blood 81(12):3382-87
-
(1993)
Blood
, vol.81
, Issue.12
, pp. 3382-3387
-
-
Greipp, P.R.1
Lust, J.A.2
O'Fallon, W.M.3
-
25
-
-
2942692143
-
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
-
Papandreou CN, Daliani DD, Nix D, et al. 2004. Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J. Clin. Oncol. 22(11):2108-21
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.11
, pp. 2108-2121
-
-
Papandreou, C.N.1
Daliani, D.D.2
Nix, D.3
-
26
-
-
20044381304
-
Bortezomib in relapsed and/or refractory multiple myeloma: Initial clinical experience in patients with impaired renal function
-
Jagannath S, Barlogie B, Berenson JR, et al. 2005. Bortezomib in relapsed and/or refractory multiple myeloma: initial clinical experience in patients with impaired renal function. Cancer 103(6):1195-2000
-
(2005)
Cancer
, vol.103
, Issue.6
, pp. 1195-2000
-
-
Jagannath, S.1
Barlogie, B.2
Berenson, J.R.3
-
27
-
-
2342568422
-
Pharmacokinetics of gemcitabine and the proteasome inhibitor bortezomib (formerly PS-341) in adult patients with solid malignancies
-
Nix D, Ryan DP, Eder JP, et al. 2003. Pharmacokinetics of gemcitabine and the proteasome inhibitor bortezomib (formerly PS-341) in adult patients with solid malignancies. Proc. Am. Assoc. Cancer. Res. 44(2):1061
-
(2003)
Proc. Am. Assoc. Cancer. Res.
, vol.44
, Issue.2
, pp. 1061
-
-
Nix, D.1
Ryan, D.P.2
Eder, J.P.3
-
28
-
-
23944433067
-
Pharmacokinetics of irinotecan and the proteasome inhibitor bortezomib in adult patients with solid malignancies
-
Supko JG, Eder JP, Lynch TJ, et al. 2003. Pharmacokinetics of irinotecan and the proteasome inhibitor bortezomib in adult patients with solid malignancies. Proc. Am. Soc. Clin. Oncol. 22:136
-
(2003)
Proc. Am. Soc. Clin. Oncol.
, vol.22
, pp. 136
-
-
Supko, J.G.1
Eder, J.P.2
Lynch, T.J.3
-
32
-
-
2542481724
-
Phase I study of bortezomib in refractory or relapsed acute leukemias
-
Cortes J, Thomas D, Koller C, et al. 2004. Phase I study of bortezomib in refractory or relapsed acute leukemias. Clin. Cancer Res. 10(10):3371-76
-
(2004)
Clin. Cancer Res.
, vol.10
, Issue.10
, pp. 3371-3376
-
-
Cortes, J.1
Thomas, D.2
Koller, C.3
-
33
-
-
32844455254
-
Bortezomib in combination with melphalan in the treatment of relapsed or refractory multiple myeloma: A phase I/II study
-
Berenson J, Yang H, Swift R, et al. 2005. Bortezomib in combination with melphalan in the treatment of relapsed or refractory multiple myeloma: a phase I/II study. Haematologica 90(Suppl. 1):150-51
-
(2005)
Haematologica
, vol.90
, Issue.SUPPL. 1
, pp. 150-151
-
-
Berenson, J.1
Yang, H.2
Swift, R.3
-
34
-
-
20144387627
-
Phase I study of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
-
Orlowski R, Voorhees P, Garcia R, et al. 2005. Phase I study of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 105(8):3058-65
-
(2005)
Blood
, vol.105
, Issue.8
, pp. 3058-3065
-
-
Orlowski, R.1
Voorhees, P.2
Garcia, R.3
-
35
-
-
14744272160
-
Survival, duration of response, and time to progression with bortezomib in patients with relapsed and refractory myeloma: An update of the SUMMIT trial with additional follow-up
-
Richardson PG, Barlogie B, Berenson J, et al. 2004. Survival, duration of response, and time to progression with bortezomib in patients with relapsed and refractory myeloma: an update of the SUMMIT trial with additional follow-up. Hematol. J. 5(Suppl. 2):S103-4
-
(2004)
Hematol. J.
, vol.5
, Issue.SUPPL. 2
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
-
36
-
-
18244428600
-
Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation
-
Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant
-
Bladé J, Samson D, Reece D, et al. 1998. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br. J. Haematol. 102(5):1115-23
-
(1998)
Br. J. Haematol.
, vol.102
, Issue.5
, pp. 1115-1123
-
-
Bladé, J.1
Samson, D.2
Reece, D.3
-
37
-
-
21344442325
-
Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma
-
Jagannath S, Richardson P, Barlogie B, et al. 2004. Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma. Hematol. J. 5(Suppl. 2):S130
-
(2004)
Hematol. J.
, vol.5
, Issue.SUPPL. 2
-
-
Jagannath, S.1
Richardson, P.2
Barlogie, B.3
-
38
-
-
21344435052
-
PAD combination therapy (bortezomib, formerly PS-341, Adriamycin and dexamethasone) for previously untreated patients with multiple myeloma
-
Oakervee HE, Popat R, Curry N, et al. 2005. PAD combination therapy (bortezomib, formerly PS-341, Adriamycin and dexamethasone) for previously untreated patients with multiple myeloma. Br. J. Haematol. 129(6):755-62
-
(2005)
Br. J. Haematol.
, vol.129
, Issue.6
, pp. 755-762
-
-
Oakervee, H.E.1
Popat, R.2
Curry, N.3
-
39
-
-
21344469223
-
Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma
-
Jagannath S, Durie B, Wolf J, et al. 2005. Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br. J. Haematol. 129(6):776-83
-
(2005)
Br. J. Haematol.
, vol.129
, Issue.6
, pp. 776-783
-
-
Jagannath, S.1
Durie, B.2
Wolf, J.3
-
40
-
-
20044396543
-
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
-
Goy A, Younes P, McLaughlin P, et al. 2005. Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J. Clin. Oncol. 23(4):667-75
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.4
, pp. 667-675
-
-
Goy, A.1
Younes, P.2
McLaughlin, P.3
-
41
-
-
20044376092
-
Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
-
O'Connor OA, Wright J, Moskowitz CH, et al. 2005. Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J. Clin. Oncol. 23(4):676-84
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.4
, pp. 676-684
-
-
O'Connor, O.A.1
Wright, J.2
Moskowitz, C.H.3
-
42
-
-
3142645636
-
A phase II study of bortezomib in patients with mantle cell lymphoma
-
Abstr.
-
Assouline S, Belch A, Sehn L, et al. 2003. A phase II study of bortezomib in patients with mantle cell lymphoma. Blood 102:902a (Abstr.)
-
(2003)
Blood
, vol.102
-
-
Assouline, S.1
Belch, A.2
Sehn, L.3
-
43
-
-
4644304196
-
Phase II trial of bortezomib for patients with advanced renal cell carcinoma
-
Kondagunta GV, Drucker B, Schwartz L, et al. 2004. Phase II trial of bortezomib for patients with advanced renal cell carcinoma. J. Clin. Oncol. 22(18):3720-25
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.18
, pp. 3720-3725
-
-
Kondagunta, G.V.1
Drucker, B.2
Schwartz, L.3
-
44
-
-
2442510143
-
Phase II trial of PS-341 in patients with renal cell cancer: A University of Chicago phase II consortium study
-
Davis NB, Taber DA, Ansari RH, et al. 2004. Phase II trial of PS-341 in patients with renal cell cancer: a University of Chicago phase II consortium study. J. Clin. Oncol. 22(1):115-19
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.1
, pp. 115-119
-
-
Davis, N.B.1
Taber, D.A.2
Ansari, R.H.3
-
45
-
-
18844421493
-
Bortezomib ± irinotecan in relapsed/refractory colorectal cancer (CRC): Interim analysis results from a phase (ph) 2b study
-
Dragovich T, Lenz HJ, Rocha Lima CMS, et al. 2004. Bortezomib ± irinotecan in relapsed/refractory colorectal cancer (CRC): interim analysis results from a phase (ph) 2b study. J. Clin. Oncol. 22(Suppl. 14):267s
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL. 14
-
-
Dragovich, T.1
Lenz, H.J.2
Rocha Lima, C.M.S.3
-
46
-
-
10044292218
-
Phase (ph) 2 study of bortezomib ± docetaxel in previously treated patients (pts) with advanced non-small cell lung cancer (NSCLC). Preliminary results
-
Fanucchi MP, Belt RJ, Fossella FV, et al. 2004. Phase (ph) 2 study of bortezomib ± docetaxel in previously treated patients (pts) with advanced non-small cell lung cancer (NSCLC). Preliminary results. J. Clin. Oncol. 22(Suppl. 14):643s
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL. 14
-
-
Fanucchi, M.P.1
Belt, R.J.2
Fossella, F.V.3
-
47
-
-
17644379243
-
Phase II/pharmacodynamic trial of PS-341 (bortezomib, VELCADE®) in advanced non-small cell lung cancer
-
Stevenson J, Nho CW, Johnson SW, et al. 2004. Phase II/pharmacodynamic trial of PS-341 (bortezomib, VELCADE®) in advanced non-small cell lung cancer. J. Clin. Oncol. 22(Suppl. 14):652s
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL. 14
-
-
Stevenson, J.1
Nho, C.W.2
Johnson, S.W.3
-
48
-
-
12744268798
-
Phase I/II trial of VELCADE® plus docetaxel in patients with advanced androgen-independent prostate cancer
-
Dreicer R, Roth B, Petrylak D, et al. 2004. Phase I/II trial of VELCADE® plus docetaxel in patients with advanced androgen-independent prostate cancer. J. Clin. Oncol. 22(Suppl. 14):420s
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL. 14
-
-
Dreicer, R.1
Roth, B.2
Petrylak, D.3
-
49
-
-
4644248931
-
Phase II study of the proteasome inhibitor bortezomib (PS-341) in patients with metastatic neuroendocrine tumors. Clin
-
Shah MH, Young D, Kindler HL, et al. 2004. Phase II study of the proteasome inhibitor bortezomib (PS-341) in patients with metastatic neuroendocrine tumors. Clin. Cancer Res. 10(18, Pt. 1):6111-18
-
(2004)
Cancer Res.
, vol.10
, Issue.18 PART. 1
, pp. 6111-6118
-
-
Shah, M.H.1
Young, D.2
Kindler, H.L.3
-
50
-
-
10344236596
-
Phase I/II trial of bortezomib (VELCADE®) in patients with unresectable hepatocellular carcinoma
-
Hegewisch-Becker S, Sterneck M, Schubert U, et al. 2004. Phase I/II trial of bortezomib (VELCADE®) in patients with unresectable hepatocellular carcinoma. J. Clin. Oncol. 22(Suppl. 14):335s
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL. 14
-
-
Hegewisch-Becker, S.1
Sterneck, M.2
Schubert, U.3
-
51
-
-
20444433230
-
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
-
Richardson P, Sonneveld P, Schuster MW, et al. 2005. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N. Engl. J. Med. 352(24):2487-98
-
(2005)
N. Engl. J. Med.
, vol.352
, Issue.24
, pp. 2487-2498
-
-
Richardson, P.1
Sonneveld, P.2
Schuster, M.W.3
-
52
-
-
32944463815
-
-
47a. U.S. Food and Drug Administration, http: //www.fda.gov/medwatch/ SAFETY/2004 /may04.htm. Accessed July 12, 2005
-
-
-
-
53
-
-
27644510071
-
Safety of prolonged therapy with bortezomib in relapsed/refractory multiple myeloma
-
In press
-
Berenson JR, Jagannath S, Barlogie B, et al. 2005. Safety of prolonged therapy with bortezomib in relapsed/refractory multiple myeloma. Cancer. In press
-
(2005)
Cancer
-
-
Berenson, J.R.1
Jagannath, S.2
Barlogie, B.3
-
54
-
-
22444435861
-
Evaluation of the severity and risk of thrombocytopenia with bortezomib therapy in relapsed and refractory multiple myeloma
-
Lonial L, Waller EK, Richardson PG, et al. 2004. Evaluation of the severity and risk of thrombocytopenia with bortezomib therapy in relapsed and refractory multiple myeloma. Hematol. J. 5(Suppl. 2):S130-31
-
(2004)
Hematol. J.
, vol.5
, Issue.SUPPL. 2
-
-
Lonial, L.1
Waller, E.K.2
Richardson, P.G.3
-
55
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg AL. 2003. Protein degradation and protection against misfolded or damaged proteins. Nature 426(6968):895-99
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 895-899
-
-
Goldberg, A.L.1
-
56
-
-
2342667387
-
The development of proteasome inhibitors as anticancer drugs
-
Adams J. 2004. The development of proteasome inhibitors as anticancer drugs. Cancer Cell 5(5):417-21
-
(2004)
Cancer Cell
, vol.5
, Issue.5
, pp. 417-421
-
-
Adams, J.1
-
57
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J. 2004. The proteasome: a suitable antineoplastic target. Nat. Rev. Cancer 4(5):349-60
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.5
, pp. 349-360
-
-
Adams, J.1
|