The Development of a Metabonomic-Based Drug Safety Testing Paradigm

Toxicogenomics: A Powerful Tool for Toxicity Assessment

Volumn , Issue , 2008, Pages 309-343

  Coen, Muireann ^a   Holmes, Elaine ^a   Nicholson, Jeremy K ^a   Lindon, John C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Consortium on Metabonomic Toxicology (COMET) projects; COnsortium on MEtabonomic Toxicology (COMET 2); Metabonomic expert system; Metabonomic based drug safety testing paradigm; Metabonomics and NMR and HPLC MS; Multivariate statistical batch processing and NMR spectral data; O PLS DA modeling and 'binned' UPLC MS data; Pharmacometabonomics pre dose metabolite profile response prediction

Indexed keywords

EID: 79952333874     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470699638.ch18     Document Type: Chapter

References (118)

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