High-resolution magic angle spinning 1H NMR spectroscopy of intact liver and kidney: Optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition

Analytical Biochemistry

Volumn 282, Issue 1, 2000, Pages 16-23

  Waters, N J ^a   Garrod, S ^a   Farrant, R D ^b   Haselden, J N ^b   Connor, S C ^b   Connelly, J ^b   Lindon, J C ^a   Holmes, E ^a   Nicholson, J K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Biochemical stability; Liver; Magic angle spinning; MAS 1H NMR spectroscopy; Renal cortex

Indexed keywords

AMINO ACIDS; FREEZING; LIVER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TISSUE;

1H NMR SPECTROSCOPY; BIOCHEMICAL COMPOSITION; BIOCHEMICAL STABILITY; HIGH RESOLUTION MAGIC ANGLE SPINNING; RENAL CORTEX; SAMPLE PREPARATION PROCEDURE; SPECTRAL ACQUISITION; TEMPERATURE CONDITIONS;

MAGIC ANGLE SPINNING;

ALPHA AMINO ACID; INOSITOL; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFACT REDUCTION; CONTROLLED STUDY; DEGRADATION; FREEZING; KIDNEY CORTEX; LIVER; MALE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SAMPLING; TEMPERATURE; TRANSAMINATION;

ANIMALIA;

EID: 0034660325     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2000.4574     Document Type: Article

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