Analytical reproducibility in 1H NMR-based metabonomic urinalysis

Chemical Research in Toxicology

Volumn 15, Issue 11, 2002, Pages 1380-1386

  Keun, Hector C ^a   Ebbels, Timothy M D ^a   Antti, Henrik ^a   Bollard, Mary E ^a   Beckonert, Olaf ^a   Schlotterbeck, Götz ^b   Senn, Hans ^b   Niederhauser, Urs ^b   Holmes, Elaine ^a   Lindon, John C ^a   Nicholson, Jeremy K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CITRIC ACID; HIPPURIC ACID; HYDRAZINE; TAURINE; XENOBIOTIC AGENT; HYDRAZINE DERIVATIVE;

ADOLESCENT; ANALYTICAL ERROR; ANIMAL TISSUE; ARTICLE; BODY FLUID; CHEMICAL ANALYSIS; CHEMOMETRIC ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; MALE; METABOLIC REGULATION; MODEL; NONHUMAN; PREDICTION; PRINCIPAL COMPONENT ANALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITY CONTROL; RAT; REPRODUCIBILITY; STATISTICS; TECHNIQUE; TISSUE; TOXICOLOGY; URINALYSIS; VARIANCE; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; INSTRUMENTATION; LABORATORY DIAGNOSIS; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBSERVER VARIATION; SPRAGUE DAWLEY RAT; URINE;

ANIMALIA;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDRAZINES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLISM; OBSERVER VARIATION; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECIMEN HANDLING; TOXICOLOGY; URINALYSIS; URINE;

EID: 18744396052     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0255774     Document Type: Article

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