-
1
-
-
33746540478
-
Genome-wide genetic association of complex traits in heterogeneous stock mice
-
Valdar, W. et al. Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat. Genet. 38, 879-887 (2006).
-
(2006)
Nat. Genet
, vol.38
, pp. 879-887
-
-
Valdar, W.1
-
2
-
-
0028285005
-
Quantitative trait loci underlying gene product variation: A novel perspective for analyzing regulation of genome expression
-
Damerval, C., Maurice, A., Josse, J.M. & de Vienne, D. Quantitative trait loci underlying gene product variation: a novel perspective for analyzing regulation of genome expression. Genetics 137, 289-301 (1994).
-
(1994)
Genetics
, vol.137
, pp. 289-301
-
-
Damerval, C.1
Maurice, A.2
Josse, J.M.3
de Vienne, D.4
-
3
-
-
18544382234
-
Genetic analysis of the mouse brain proteome
-
Klose, J. et al. Genetic analysis of the mouse brain proteome. Nat. Genet. 30, 385-393 (2002).
-
(2002)
Nat. Genet
, vol.30
, pp. 385-393
-
-
Klose, J.1
-
4
-
-
33750204290
-
Genetics of global gene expression
-
Rockman, M.V. & Kruglyak, L. Genetics of global gene expression. Nat. Rev. Genet. 7, 862-872 (2006).
-
(2006)
Nat. Rev. Genet
, vol.7
, pp. 862-872
-
-
Rockman, M.V.1
Kruglyak, L.2
-
5
-
-
33745580270
-
The genetics of plant metabolism
-
Keurentjes, J.J. et al. The genetics of plant metabolism. Nat. Genet. 38, 842-849 (2006).
-
(2006)
Nat. Genet
, vol.38
, pp. 842-849
-
-
Keurentjes, J.J.1
-
6
-
-
0036463681
-
Metabonomics: A platform for studying drug toxicity and gene function
-
Nicholson, J.K., Connelly, J., Lindon, J.C. & Holmes, E. Metabonomics: a platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 1, 153-161 (2002).
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
Holmes, E.4
-
7
-
-
0034646538
-
Infectious history
-
Lederberg, J. Infectious history. Science 288, 287-293 (2000).
-
(2000)
Science
, vol.288
, pp. 287-293
-
-
Lederberg, J.1
-
8
-
-
33845874101
-
An obesity-associated gut microbiome with increased capacity for energy harvest
-
Turnbaugh, P.J. et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444, 1027-1031 (2006).
-
(2006)
Nature
, vol.444
, pp. 1027-1031
-
-
Turnbaugh, P.J.1
-
9
-
-
15944376562
-
Strategies for mapping and cloning quantitative trait genes in rodents
-
Flint, J., Valdar, W., Shifman, S. & Mott, R. Strategies for mapping and cloning quantitative trait genes in rodents. Nat. Rev. Genet. 6, 271-286 (2005).
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 271-286
-
-
Flint, J.1
Valdar, W.2
Shifman, S.3
Mott, R.4
-
10
-
-
0032694577
-
Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson, J.K., Lindon, J.C. & Holmes, E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29, 1181-1189 (1999).
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
11
-
-
5044229817
-
The challenges of modeling mammalian biocomplexity
-
Nicholson, J.K., Holmes, E., Lindon, J.C. & Wilson, I.D. The challenges of modeling mammalian biocomplexity. Nat. Biotechnol. 22, 1268-1274 (2004).
-
(2004)
Nat. Biotechnol
, vol.22
, pp. 1268-1274
-
-
Nicholson, J.K.1
Holmes, E.2
Lindon, J.C.3
Wilson, I.D.4
-
12
-
-
33646198860
-
Pharmaco-metabonomic phenotyping and personalized drug treatment
-
Clayton, T.A. et al. Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature 440, 1073-1077 (2006).
-
(2006)
Nature
, vol.440
, pp. 1073-1077
-
-
Clayton, T.A.1
-
13
-
-
33645746673
-
Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement
-
Schauer, N. et al. Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement. Nat. Biotechnol. 24, 447-454 (2006).
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 447-454
-
-
Schauer, N.1
-
14
-
-
33745677702
-
Genetical metabolomics of flavonoid biosynthesis in Populus: A case study
-
Morreel, K. et al. Genetical metabolomics of flavonoid biosynthesis in Populus: a case study. Plant J. 47, 224-237 (2006).
-
(2006)
Plant J
, vol.47
, pp. 224-237
-
-
Morreel, K.1
-
15
-
-
0035400051
-
Genetical genomics: The added value from segregation
-
Jansen, R.C. & Nap, J.P. Genetical genomics: the added value from segregation. Trends Genet. 17, 388-391 (2001).
-
(2001)
Trends Genet
, vol.17
, pp. 388-391
-
-
Jansen, R.C.1
Nap, J.P.2
-
16
-
-
0030957846
-
A linkage map of the rat genome derived from three F2 crosses
-
Bihoreau, M.T. et al. A linkage map of the rat genome derived from three F2 crosses. Genome Res. 7, 434-440 (1997).
-
(1997)
Genome Res
, vol.7
, pp. 434-440
-
-
Bihoreau, M.T.1
-
17
-
-
9044247460
-
Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat
-
Gauguier, D. et al. Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat. Genet. 12, 38-43 (1996).
-
(1996)
Nat. Genet
, vol.12
, pp. 38-43
-
-
Gauguier, D.1
-
18
-
-
0037958742
-
R/qtl: QTL mapping in experimental crosses
-
Broman, K.W., Wu, H., Sen, S. & Churchill, G.A. R/qtl: QTL mapping in experimental crosses. Bioinformatics 19, 889-890 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 889-890
-
-
Broman, K.W.1
Wu, H.2
Sen, S.3
Churchill, G.A.4
-
19
-
-
20144377218
-
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
-
Hubner, N. et al. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat. Genet. 37, 243-253 (2005).
-
(2005)
Nat. Genet
, vol.37
, pp. 243-253
-
-
Hubner, N.1
-
20
-
-
0034368580
-
Metabonomics: Metabolic processes studied by NMR spectroscopy of biofluids
-
Lindon, J.C., Nicholson, J.K., Holmes, E. & Everett, J.R. Metabonomics: Metabolic processes studied by NMR spectroscopy of biofluids. Concepts Magn. Reson. 12, 289-320 (2000).
-
(2000)
Concepts Magn. Reson
, vol.12
, pp. 289-320
-
-
Lindon, J.C.1
Nicholson, J.K.2
Holmes, E.3
Everett, J.R.4
-
21
-
-
34247612266
-
Genetic control of plasma lipid levels in a cross derived from normoglycaemic Brown Norway and spontaneously diabetic Goto-Kakizaki rats
-
Argoud, K. et al. Genetic control of plasma lipid levels in a cross derived from normoglycaemic Brown Norway and spontaneously diabetic Goto-Kakizaki rats. Diabetologia 49, 2679-2688 (2006).
-
(2006)
Diabetologia
, vol.49
, pp. 2679-2688
-
-
Argoud, K.1
-
22
-
-
34247636528
-
The rat as a model physiological system
-
eds. Jorde, L.B, Little, P, Dunn, M. & Subramaniam, S, Wiley, London, U.K
-
Gauguier, D. The rat as a model physiological system. in Encyclopedia of Genetics Vol. 3 (eds. Jorde, L.B., Little, P., Dunn, M. & Subramaniam, S.) 1154-1171 (Wiley, London, U.K., 2006).
-
(2006)
Encyclopedia of Genetics
, vol.3
, pp. 1154-1171
-
-
Gauguier, D.1
-
23
-
-
0043069547
-
Opinion: Understanding 'global' systems biology: metabonomics and the continuum of metabolism
-
Nicholson, J.K. & Wilson, I.D. Opinion: understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nat. Rev. Drug Discov. 2, 668-676 (2003).
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 668-676
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
24
-
-
0014807124
-
The fate of benzoic acid in various species
-
Bridges, J.W., French, M.R., Smith, R.L. & Williams, R.T. The fate of benzoic acid in various species. Biochem. J. 118, 47-51 (1970).
-
(1970)
Biochem. J
, vol.118
, pp. 47-51
-
-
Bridges, J.W.1
French, M.R.2
Smith, R.L.3
Williams, R.T.4
-
25
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
-
Tukey, R.H. & Strassburg, C.P. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu. Rev. Pharmacol. Toxicol. 40, 581-616 (2000).
-
(2000)
Annu. Rev. Pharmacol. Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
26
-
-
20344375263
-
Mutated G-protein-coupled receptor GPR10 is responsible for the hyperphagia/dyslipidaemia/obesity locus of Dmo1 in the OLETF rat
-
Watanabe, T.K. et al. Mutated G-protein-coupled receptor GPR10 is responsible for the hyperphagia/dyslipidaemia/obesity locus of Dmo1 in the OLETF rat. Clin. Exp. Pharmacol. Physiol. 32, 355-366 (2005).
-
(2005)
Clin. Exp. Pharmacol. Physiol
, vol.32
, pp. 355-366
-
-
Watanabe, T.K.1
-
27
-
-
33745225182
-
Mapping diabetes QTL in an intercross derived from a congenic strain of the Brown Norway and Goto-Kakizaki rats
-
Collins, S.C. et al. Mapping diabetes QTL in an intercross derived from a congenic strain of the Brown Norway and Goto-Kakizaki rats. Mamm. Genome 17, 538-547 (2006).
-
(2006)
Mamm. Genome
, vol.17
, pp. 538-547
-
-
Collins, S.C.1
-
28
-
-
33747618036
-
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice
-
Dumas, M.E. et al. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc. Natl. Acad. Sci. USA 103, 12511-12516 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12511-12516
-
-
Dumas, M.E.1
-
29
-
-
4043153183
-
Integration of the rat recombination and EST maps in the rat genomic sequence and comparative mapping analysis with the mouse genome
-
Wilder, S.P. et al. Integration of the rat recombination and EST maps in the rat genomic sequence and comparative mapping analysis with the mouse genome. Genome Res. 14, 758-765 (2004).
-
(2004)
Genome Res
, vol.14
, pp. 758-765
-
-
Wilder, S.P.1
-
30
-
-
4143076901
-
Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies
-
Dudbridge, F. & Koeleman, B.P. Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies. Am. J. Hum. Genet. 75, 424-435 (2004).
-
(2004)
Am. J. Hum. Genet
, vol.75
, pp. 424-435
-
-
Dudbridge, F.1
Koeleman, B.P.2
|