Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

Chemical Research in Toxicology

Volumn 17, Issue 5, 2004, Pages 579-587

  Keun, Hector C ^a   Ebbels, Timothy M D ^a   Bollard, Mary E ^a   Beckonert, Olaf ^a   Antti, Henrik ^a   Holmes, Elaine ^a   Lindon, John C ^a   Nicholson, Jeremy K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; HYDRAZINE;

ARTICLE; COMPARATIVE STUDY; GENOMICS; MEASUREMENT; METABOLISM; MODEL; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; PROTEOMICS; SAFETY; SPECIES DIFFERENCE; TOXICITY TESTING;

ANIMALS; BROMOBENZENES; DATABASES, FACTUAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDRAZINES; MULTIVARIATE ANALYSIS; PATTERN RECOGNITION, AUTOMATED; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TOXICOLOGY; TOXINS, BIOLOGICAL;

EID: 2442651602     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034212w     Document Type: Article

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