Chemometric models for toxicity classification based on NMR spectra of biofluids

Chemical Research in Toxicology

Volumn 13, Issue 6, 2000, Pages 471-478

  Holmes, Elaine ^a   Nicholls, Andrew W ^a   Lindon, John C ^a   Connor, Susan C ^b   Connelly, John C ^b   Haselden, John N ^b   Damment, Stephen J P ^b   Spraul, Manfred ^c   Neidig, Peter ^c   Nicholson, Jeremy K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Bruker Analytik GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYDRAZINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FLUID COMPARTMENT; CHEMOMETRIC ANALYSIS; CONTROLLED STUDY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TOXICITY TESTING; TOXICOKINETICS; URINALYSIS;

ANIMALS; BIOTRANSFORMATION; DRUG TOXICITY; FACTOR ANALYSIS, STATISTICAL; HYDRAZINES; KIDNEY CORTEX; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MERCURIC CHLORIDE; MODELS, CHEMICAL; PATTERN RECOGNITION, AUTOMATED; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0034130232     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx990210t     Document Type: Article

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