Contemporary issues in toxicology: The role of metabonomics in toxicology and its evaluation by the COMET project

Toxicology and Applied Pharmacology

Volumn 187, Issue 3, 2003, Pages 137-146

  Lindon, John C ^a   Nicholson, Jeremy K ^a   Holmes, Elaine ^a   Antti, Henrik ^a,i   Bollard, Mary E ^a   Keun, Hector ^a   Beckonert, Olaf ^a   Ebbels, Timothy M ^a   Reily, Michael D ^b   Robertson, Donald ^b   Stevens, Gregory J ^c   Luke, Peter ^d   Breau, Alan P ^b   Cantor, Glenn H ^b   Bible, Roy H ^b   Niederhauser, Urs ^e   Senn, Hans ^e   Schlotterbeck, Goetz ^e   Sidelmann, Ulla G ^f   Laursen, Steen M ^f   Tymiak, Adrienne ^g   Car, Bruce D ^g   Lehman McKeeman, Lois ^g   Colet, Jean Marie ^h   Loukaci, Ali ^h   Thomas, Craig ^h,j   more..

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b PFIZER INC   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

^f NOVO NORDISK A S   (Denmark)

^g BRISTOL MYERS SQUIBB   (United States)

^h Eli Lilly Benelux   (Belgium)

ⁱ Metabometrix Ltd   (United Kingdom)

^j ELI LILLY AND COMPANY   (United States)

more..

Author keywords

Chemometrics; Expert system; Metabonomics; NMR; Pharmaceutical; Toxin

Indexed keywords

HYDRAZINE; TOXIN;

ARTICLE; BIOCHEMICAL COMPOSITION; CHEMOMETRIC ANALYSIS; COMPUTER SYSTEM; EXPERT SYSTEM; LIVER TOXICITY; METABONOMICS; MULTIVARIATE ANALYSIS; NEPHROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; REPRODUCIBILITY; SCREENING TEST; SERUM; STATISTICAL MODEL; TOXICOLOGY; URINE;

EID: 0037444362     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(02)00079-0     Document Type: Article

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