Development of a model for classification of toxin-induced lesions using 1H NMR spectroscopy of urine combined with pattern recognition

NMR in Biomedicine

Volumn 11, Issue 4-5, 1998, Pages 235-244

  Holmes, E ^a   Nicholls, A W ^a   Lindon, J C ^a   Ramos, S ^b   Spraul, M ^c   Neidig, P ^c   Connor, S C ^d   Connelly, J ^d   Damment, S J P ^d   Haselden, J ^d   Nicholson, J K ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Infometrix Inc   (United States)

^c Bruker Analytik GmbH   (Germany)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Biomarker; Hepatotoxin; Nephrotoxin; Nuclear magnetic resonance (NMR) spectroscopy; Principal components analysis (PCA); SIMCA

Indexed keywords

BIOLOGICAL MARKER; HYDRAZINE; PUROMYCIN; THIOACETAMIDE; TOXIN;

ACIDURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FLUID; CELL DAMAGE; CONTROLLED STUDY; DATA ANALYSIS; METABOLITE; MODEL; NONHUMAN; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TOXICITY TESTING; URINALYSIS;

ANIMALS; DATA INTERPRETATION, STATISTICAL; IMAGE PROCESSING, COMPUTER-ASSISTED; KIDNEY DISEASES; LIVER DISEASES; MALE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PATTERN RECOGNITION, AUTOMATED; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; TOXINS, BIOLOGICAL;

ANIMALIA; TRIFLUORO;

EID: 7344256122     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199806/08)11:4/5<235::AID-NBM507>3.0.CO;2-V     Document Type: Article

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