An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

Chemical Research in Toxicology

Volumn 16, Issue 3, 2003, Pages 295-303

  Coen, Muireann ^a   Lenz, Eva M ^b   Nicholson, Jeremy K ^a   Wilson, Ian D ^b   Pognan, Francois ^b   Lindon, John C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CITRIC ACID; FATTY ACID; PARACETAMOL; PHOSPHOLIPID; PYRUVIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG INTOXICATION; FATTY ACID OXIDATION; GLYCOLYSIS; HISTOPATHOLOGY; LIVER MICROSOME; LIVER TOXICITY; MOUSE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE;

ACETAMINOPHEN; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; GLYCOGEN; LIPID METABOLISM; LIPIDS; LIVER; LIVER EXTRACTS; MALE; MICE; MITOCHONDRIA, LIVER; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PRINCIPAL COMPONENT ANALYSIS; TIME FACTORS;

ANIMALIA;

EID: 0037348405     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0256127     Document Type: Article

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