Application of directly coupled high performance liquid chromatography-nmr-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in sprague-dawley rats

Drug Metabolism and Disposition

Volumn 30, Issue 12, 2002, Pages 1357-1363

  Connelly, John C ^a,b   Connor, Susan C ^a,c   Monte, Soria ^a,d   Bailey, Nigel J C ^a   Borgeaud, Nathan ^a   Holmes, Elaine ^a   Troke, Jeff ^a   Nicholson, Jeremy K ^a   Gavaghan, Claire L ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Metabometrix Ltd   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d Department of Analytical Sciences ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE DERIVATIVE; BENZOFURAN DERIVATIVE; FURAN; PHENYLACETIC ACID DERIVATIVE; BENZOFURAN;

ANALYTIC METHOD; ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; URINALYSIS; URINARY EXCRETION; ANIMAL; CHEMISTRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; SPRAGUE DAWLEY RAT;

ANIMALS; BENZOFURANS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036891959     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.12.1357     Document Type: Article

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