메뉴 건너뛰기




Volumn 12, Issue , 2010, Pages

Oxidation and age-related macular degeneration: Insights from molecular biology

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CRYPTOXANTHIN; CAROTENE; CAROTENOID; CERULOPLASMIN; COPPER; GLUTATHIONE PEROXIDASE; LIPOFUSCIN; LYCOPENE; MELANIN; MELATONIN; MITOCHONDRIAL DNA; N RETINYLIDENE N RETINYLETHANOLAMINE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VASCULOTROPIN; XANTHOPHYLL; ZEAXANTHIN; REACTIVE OXYGEN METABOLITE;

EID: 79952112401     PISSN: 14623994     EISSN: None     Source Type: Journal    
DOI: 10.1017/S146239941000164X     Document Type: Review
Times cited : (165)

References (223)
  • 6
    • 77952891296 scopus 로고    scopus 로고
    • Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age related macular degeneration
    • Schmitz-Valckenberg, S. et al. (2010) Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age related macular degeneration. Ophthalmology 117, 1169-1176
    • (2010) Ophthalmology , vol.117 , pp. 1169-1176
    • Schmitz-Valckenberg, S.1
  • 7
    • 38349170724 scopus 로고    scopus 로고
    • The epidemiology of retinal reticular drusen
    • Klein, R. et al. (2008) The epidemiology of retinal reticular drusen. American Journal of Ophthalmology 145, 317-326
    • (2008) American Journal of Ophthalmology , vol.145 , pp. 317-326
    • Klein, R.1
  • 9
    • 35448975681 scopus 로고    scopus 로고
    • Progress in defining the molecular biology of age related macular degeneration
    • DOI 10.1007/s00439-007-0406-3
    • Lotery, A. and Trump, D. (2007) Progress in defining the molecular biology of age related macular degeneration. Human Genetics 122, 219-236 (Pubitemid 47616531)
    • (2007) Human Genetics , vol.122 , Issue.3-4 , pp. 219-236
    • Lotery, A.1    Trump, D.2
  • 10
    • 33645890840 scopus 로고    scopus 로고
    • Prevalence of age-related maculopathy in older Europeans: The European Eye Study (EUREYE)
    • Augood, C.A. et al. (2006) Prevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE). Archives of Ophthalmology 124, 529-535
    • (2006) Archives of Ophthalmology , vol.124 , pp. 529-535
    • Augood, C.A.1
  • 12
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance, B., Sies, H. and Boveris, A. (1979) Hydroperoxide metabolism in mammalian organs. Physiological Reviews 59, 527-605 (Pubitemid 9236599)
    • (1979) Physiological Reviews , vol.59 , Issue.3 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 13
    • 0035975713 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations, oxidative stress, and aging
    • Golden, T.R. and Melov, S. (2001) Mitochondrial DNA mutations, oxidative stress, and aging. Mechanisms of Ageing and Development 122, 1577-1589
    • (2001) Mechanisms of Ageing and Development , vol.122 , pp. 1577-1589
    • Golden, T.R.1    Melov, S.2
  • 14
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick, L. and Moorhead, P.S. (1961) The serial cultivation of human diploid cell strains. Experimental Cell Research 25, 585-621
    • (1961) Experimental Cell Research , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 15
    • 0029037578 scopus 로고
    • Relevance of oxidative stress to the limited replicative capacity of culturedhumandiploid cells: The limit of cumulative population doublings increases under low concentrations of oxygen and decreases in response to aminotriazole
    • Yuan, H., Kaneko, T. and Matsuo, M. (1995) Relevance of oxidative stress to the limited replicative capacity of culturedhumandiploid cells: the limit of cumulative population doublings increases under low concentrations of oxygen and decreases in response to aminotriazole. Mechanisms of Ageing and Development 81, 159-168
    • (1995) Mechanisms of Ageing and Development , vol.81 , pp. 159-168
    • Yuan, H.1    Kaneko, T.2    Matsuo, M.3
  • 17
    • 3042822263 scopus 로고    scopus 로고
    • Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress
    • DOI 10.1016/j.yexcr.2004.04.004, PII S0014482704002010
    • Rubio, M.A., Davalos, A.R. and Campisi, J. (2004) Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress. Experimental Cell Research 298, 17-27 (Pubitemid 38887303)
    • (2004) Experimental Cell Research , vol.298 , Issue.1 , pp. 17-27
    • Rubio, M.A.1    Davalos, A.R.2    Campisi, J.3
  • 19
    • 0033991466 scopus 로고    scopus 로고
    • Oxidative damage and protection of the RPE
    • [Review] 138 Refs
    • Cai, J. et al. (2000) Oxidative damage and protection of the RPE. [Review] [138 Refs]. Progress in Retinal and Eye Research 19, 205-221
    • (2000) Progress in Retinal and Eye Research , vol.19 , pp. 205-221
    • Cai, J.1
  • 20
    • 0033579810 scopus 로고    scopus 로고
    • Mitochondrial release of caspase-2 and -9 during the apoptotic process
    • Susin, S.A. et al. (1999) Mitochondrial release of caspase-2 and -9 during the apoptotic process. Journal of Experimental Medicine 189, 381-394
    • (1999) Journal of Experimental Medicine , vol.189 , pp. 381-394
    • Susin, S.A.1
  • 22
    • 70449216883 scopus 로고
    • Lipids of biologic importance; peroxidation products and inclusion compounds of lipids
    • Lundberg, W.O. (1958) Lipids of biologic importance; peroxidation products and inclusion compounds of lipids. American Journal of Clinical Nutrition 6, 601-603
    • (1958) American Journal of Clinical Nutrition , vol.6 , pp. 601-603
    • Lundberg, W.O.1
  • 23
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman, D. (1956) Aging: a theory based on free radical and radiation chemistry. Journal of Gerontology 11, 298-300
    • (1956) Journal of Gerontology , vol.11 , pp. 298-300
    • Harman, D.1
  • 25
    • 0026524018 scopus 로고
    • Light-induced retinal damage in mice. Hydrogen peroxide production and superoxide dismutase activity in retina
    • Yamashita, H. et al. (1992) Light-induced retinal damage in mice. Hydrogen peroxide production and superoxide dismutase activity in retina. Retina 12, 59-66
    • (1992) Retina , vol.12 , pp. 59-66
    • Yamashita, H.1
  • 27
    • 70349617321 scopus 로고    scopus 로고
    • The influence of sublethal blue light exposure on human RPE cells
    • Roehlecke, C. et al. (2009) The influence of sublethal blue light exposure on human RPE cells. Molecular Vision 15, 1929-1938
    • (2009) Molecular Vision , vol.15 , pp. 1929-1938
    • Roehlecke, C.1
  • 28
    • 0027930278 scopus 로고
    • Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis
    • DOI 10.1006/excr.1994.1254
    • Miceli, M.V., Liles, M.R. and Newsome, D.A. (1994) Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis. Experimental Cell Research 214, 242-249 (Pubitemid 24302398)
    • (1994) Experimental Cell Research , vol.214 , Issue.1 , pp. 242-249
    • Miceli, M.V.1    Liles, M.R.2    Newsome, D.A.3
  • 30
    • 40949121097 scopus 로고    scopus 로고
    • Prematurely senescent ARPE-19 cells display features of age-related macular degeneration
    • Glotin, A.L. et al. (2008) Prematurely senescent ARPE-19 cells display features of age-related macular degeneration. Free Radical Biology and Medicine 44, 1348-1361
    • (2008) Free Radical Biology and Medicine , vol.44 , pp. 1348-1361
    • Glotin, A.L.1
  • 31
    • 59449099708 scopus 로고    scopus 로고
    • Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release
    • Yu, A.L. et al. (2009) Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release. Investigative Ophthalmology and Visual Science 50, 926-935
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 926-935
    • Yu, A.L.1
  • 32
    • 4544326749 scopus 로고    scopus 로고
    • Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6
    • DOI 10.1074/jbc.M402202200
    • Sanvicens, N. et al. (2004) Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6. Journal of Biological Chemistry 279, 39268-39278 (Pubitemid 39258188)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.38 , pp. 39268-39278
    • Sanvicens, N.1    Gomez-Vicente, V.2    Masip, I.3    Messeguer, A.4    Cotter, T.G.5
  • 33
    • 64849096470 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation induces CTGF and PAI-1 in cultured human retinal pigment epithelium cells
    • Fuchshofer, R. et al. (2009) Hypoxia/reoxygenation induces CTGF and PAI-1 in cultured human retinal pigment epithelium cells. Experimental Eye Research 88, 889-899
    • (2009) Experimental Eye Research , vol.88 , pp. 889-899
    • Fuchshofer, R.1
  • 34
    • 75749153035 scopus 로고    scopus 로고
    • Effects of antioxidants (AREDS medication) on ocular blood flow and endothelial function in an endotoxin-induced model of oxidative stress in humans
    • Pemp, B. et al. (2010) Effects of antioxidants (AREDS medication) on ocular blood flow and endothelial function in an endotoxin-induced model of oxidative stress in humans. Investigative Ophthalmology and Visual Science 51, 2-6
    • (2010) Investigative Ophthalmology and Visual Science , vol.51 , pp. 2-6
    • Pemp, B.1
  • 35
    • 0025084372 scopus 로고
    • Hematogenous photosensitization: A mechanism for the development of age-related macular degeneration
    • Gottsch, J.D. et al. (1990) Hematogenous photosensitization. A mechanism for the development of age-related macular degeneration. Investigative Ophthalmology and Visual Science 31, 1674-1682 (Pubitemid 20350888)
    • (1990) Investigative Ophthalmology and Visual Science , vol.31 , Issue.9 , pp. 1674-1682
    • Gottsch, J.D.1    Pou, S.2    Bynoe, L.A.3    Rosen, G.M.4
  • 36
    • 70349577517 scopus 로고    scopus 로고
    • Association of superoxide anions with retinal pigment epithelial cell apoptosis induced by mononuclear phagocytes
    • Yang, D. et al. (2009) Association of superoxide anions with retinal pigment epithelial cell apoptosis induced by mononuclear phagocytes. Investigative Ophthalmology and Visual Science 50, 4998-5005
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 4998-5005
    • Yang, D.1
  • 37
    • 33947160639 scopus 로고    scopus 로고
    • Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments
    • DOI 10.1016/j.exer.2006.11.015, PII S001448350600457X
    • Chen, M., Forrester, J.V. and Xu, H. (2007) Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments. Experimental Eye Research 84, 635-645 (Pubitemid 46400631)
    • (2007) Experimental Eye Research , vol.84 , Issue.4 , pp. 635-645
    • Chen, M.1    Forrester, J.V.2    Xu, H.3
  • 38
    • 67650547973 scopus 로고    scopus 로고
    • Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury
    • Thurman, J.M. et al. (2009) Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury. Journal of Biological Chemistry 284, 16939-16947
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 16939-16947
    • Thurman, J.M.1
  • 40
    • 68349119150 scopus 로고    scopus 로고
    • Anti-inflammatory and antioxidant effects of SERPINA3 K in the retina
    • Zhang, B. et al. (2009) Anti-inflammatory and antioxidant effects of SERPINA3 K in the retina. Investigative Ophthalmology and Visual Science 50, 3943-3952
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 3943-3952
    • Zhang, B.1
  • 42
    • 33845983659 scopus 로고    scopus 로고
    • Stimulation of apical and basolateral vascular endothelial growth factor-A and vascular endothelial growth factor-C secretion by oxidative stress in polarized retinal pigment epithelial cells
    • Kannan, R. et al. (2006) Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells. Molecular Vision 12, 1649-1659 (Pubitemid 46050311)
    • (2006) Molecular Vision , vol.12 , pp. 1649-1659
    • Kannan, R.1    Zhang, N.2    Sreekumar, P.G.3    Spee, C.K.4    Rodriguez, A.5    Barron, E.6    Hinton, D.R.7
  • 43
    • 70350160127 scopus 로고    scopus 로고
    • Effects of intravitreal bevacizumab in repeated doses: An experimental study
    • Sari, A. et al. (2009) Effects of intravitreal bevacizumab in repeated doses: an experimental study. Retina 29, 1346-1355
    • (2009) Retina , vol.29 , pp. 1346-1355
    • Sari, A.1
  • 44
    • 0034775553 scopus 로고    scopus 로고
    • Antioxidant and prooxidant properties of carotenoids
    • DOI 10.1006/abbi.2000.2149
    • Young, A.J. and Lowe, G.M. (2001) Antioxidant and prooxidant properties of carotenoids. Archives of Biochemistry and Biophysics 385, 20-27 (Pubitemid 32988978)
    • (2001) Archives of Biochemistry and Biophysics , vol.385 , Issue.1 , pp. 20-27
    • Young, A.J.1    Lowe, G.M.2
  • 45
    • 0027812303 scopus 로고
    • Antioxidant action of carotenoids in vitro and in vivo and protection against oxidation of human low-density lipoproteins
    • Packer, L. (1993) Antioxidant action of carotenoids in vitro and in vivo and protection against oxidation of human low-density lipoproteins. Annal of the New York Academy of Sciences 691, 48-60
    • (1993) Annal of the New York Academy of Sciences , vol.691 , pp. 48-60
    • Packer, L.1
  • 46
    • 0026623077 scopus 로고
    • Antioxidant activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation
    • Lim, B.P. et al. (1992) Antioxidant activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation. Biochimica et Biophysica Acta 1126, 178-184
    • (1992) Biochimica et Biophysica Acta , vol.1126 , pp. 178-184
    • Lim, B.P.1
  • 48
    • 67649656071 scopus 로고    scopus 로고
    • Zeaxanthin, a retinal carotenoid, protects retinal cells against oxidative stress
    • Nakajima, Y. et al. (2009) Zeaxanthin, a retinal carotenoid, protects retinal cells against oxidative stress. Current Eye Research 34, 311-318
    • (2009) Current Eye Research , vol.34 , pp. 311-318
    • Nakajima, Y.1
  • 49
    • 51549105058 scopus 로고    scopus 로고
    • Possible degradation/biotransformation of lutein in vitro and in vivo: Isolation and structural elucidation of lutein metabolites by HPLC and LC-MS (atmospheric pressure chemical ionization)
    • Lakshminarayana, R. et al. (2008) Possible degradation/biotransformation of lutein in vitro and in vivo: isolation and structural elucidation of lutein metabolites by HPLC and LC-MS (atmospheric pressure chemical ionization). Free Radical Biology and Medicine 45, 982-993
    • (2008) Free Radical Biology and Medicine , vol.45 , pp. 982-993
    • Lakshminarayana, R.1
  • 50
    • 0030826642 scopus 로고    scopus 로고
    • Identification of lutein and zeaxanthin oxidation products in human and monkey retinas
    • Khachik, F., Bernstein, P.S. and Garland, D.L. (1997) Identification of lutein and zeaxanthin oxidation products in human and monkey retinas. Investigative Ophthalmology and Visual Science 38, 1802-1811 (Pubitemid 27382346)
    • (1997) Investigative Ophthalmology and Visual Science , vol.38 , Issue.9 , pp. 1802-1811
    • Khachik, F.1    Bernstein, P.S.2    Garland, D.L.3
  • 52
    • 0025824572 scopus 로고
    • Antioxidant enzymes in the aging human retinal pigment epithelium
    • Liles, M.R., Newsome, D.A. and Oliver, P.D. (1991) Antioxidant enzymes in the aging human retinal pigment epithelium. Archives of Ophthalmology 109, 1285-1288
    • (1991) Archives of Ophthalmology , vol.109 , pp. 1285-1288
    • Liles, M.R.1    Newsome, D.A.2    Oliver, P.D.3
  • 54
    • 0028890354 scopus 로고
    • Induction of heme oxygenase 1 in the retina by intense visible light: Suppression by the antioxidant dimethylthiourea
    • Kutty, R.K. et al. (1995) Induction of heme oxygenase 1 in the retina by intense visible light: suppression by the antioxidant dimethylthiourea. Proceedings of the National Academy of Sciences of the United States of America 92, 1177-1181
    • (1995) Proceedings of the National Academy of Sciences of the United States of America , vol.92 , pp. 1177-1181
    • Kutty, R.K.1
  • 55
    • 77049116747 scopus 로고    scopus 로고
    • Oxidative stress response in the adult rat retina and plasma after repeated administration of methamphetamine
    • Melo, P. et al. (2010) Oxidative stress response in the adult rat retina and plasma after repeated administration of methamphetamine. Neurochemistry International 56, 431-436
    • (2010) Neurochemistry International , vol.56 , pp. 431-436
    • Melo, P.1
  • 57
    • 1942487272 scopus 로고    scopus 로고
    • Melatonin protects human retinal pigment epithelial (RPE) cells against oxidative stress
    • Liang, F.Q. et al. (2004) Melatonin protects human retinal pigment epithelial (RPE) cells against oxidative stress. Experimental Eye Research 78, 1069-1075
    • (2004) Experimental Eye Research , vol.78 , pp. 1069-1075
    • Liang, F.Q.1
  • 58
    • 33747878112 scopus 로고    scopus 로고
    • (4th edn), Elsevier/Mosby, Philadelphia, PA, USA
    • Ryan, S.J. (2006) Retina (4th edn), Elsevier/Mosby, Philadelphia, PA, USA
    • (2006) Retina
    • Ryan, S.J.1
  • 60
    • 47849092882 scopus 로고    scopus 로고
    • Retinal pigment epithelium lipofuscin proteomics
    • Ng, K.P. et al. (2008) Retinal pigment epithelium lipofuscin proteomics. Molecular and Cellular Proteomics 7, 1397-1405
    • (2008) Molecular and Cellular Proteomics , vol.7 , pp. 1397-1405
    • Ng, K.P.1
  • 61
    • 0037233423 scopus 로고    scopus 로고
    • Aging of cultured retinal pigment epithelial cells: Oxidative reactions, lipofuscin formation and blue light damage
    • DOI 10.1023/A:1022419606629
    • Nilsson, S.E. et al. (2003) Aging of cultured retinal pigment epithelial cells: oxidative reactions, lipofuscin formation and blue light damage. Documenta Ophthalmologica 106, 13-16 (Pubitemid 36355966)
    • (2003) Documenta Ophthalmologica , vol.106 , Issue.1 , pp. 13-16
    • Nilsson, S.E.G.1    Sundelin, S.P.2    Wihlmark, U.3    Brunk, U.T.4
  • 62
    • 0033588376 scopus 로고    scopus 로고
    • The photoreactivity of the retinal age pigment lipofuscin
    • Wassell, J. et al. (1999) The photoreactivity of the retinal age pigment lipofuscin. Journal of Biological Chemistry 274, 23828-23832
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 23828-23832
    • Wassell, J.1
  • 63
    • 47849092882 scopus 로고    scopus 로고
    • Retinal pigment epithelium lipofuscin proteomics
    • Ng, K.P. et al. (2008) Retinal pigment epithelium lipofuscin proteomics. Molecular and Cellular Proteomics 7, 1397-1405
    • (2008) Molecular and Cellular Proteomics , vol.7 , pp. 1397-1405
    • Ng, K.P.1
  • 64
    • 0041342065 scopus 로고    scopus 로고
    • Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium
    • DOI 10.1167/iovs.03-0172
    • Schutt, F. et al. (2003) Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium. Investigative Ophthalmology and Visual Science 44, 3663-3668 (Pubitemid 36909809)
    • (2003) Investigative Ophthalmology and Visual Science , vol.44 , Issue.8 , pp. 3663-3668
    • Schutt, F.1    Bergmann, M.2    Holz, F.G.3    Kopitz, J.4
  • 65
    • 0034766880 scopus 로고    scopus 로고
    • Inhibition of RPE lysosomal and antioxidant activity by the age pigment lipofuscin
    • Shamsi, F.A. and Boulton, M. (2001) Inhibition of RPE lysosomal and antioxidant activity by the age pigment lipofuscin. Investigative Ophthalmology and Visual Science 42, 3041-3046 (Pubitemid 33035307)
    • (2001) Investigative Ophthalmology and Visual Science , vol.42 , Issue.12 , pp. 3041-3046
    • Shamsi, F.A.1    Boulton, M.2
  • 67
    • 0034086115 scopus 로고    scopus 로고
    • The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
    • Sparrow, J.R., Nakanishi, K. and Parish, C.A. (2000) The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Investigative Ophthalmology and Visual Science 41, 1981-1989 (Pubitemid 30354376)
    • (2000) Investigative Ophthalmology and Visual Science , vol.41 , Issue.7 , pp. 1981-1989
    • Sparrow, J.R.1    Nakanishi, K.2    Parish, C.A.3
  • 68
    • 0035040640 scopus 로고    scopus 로고
    • Blue light-induced apoptosis of A2E-containing RPE: Involvement of caspase-3 and protection by Bcl-2
    • Sparrow, J.R. and Cai, B. (2001) Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2. Investigative Ophthalmology and Visual Science 42, 1356-1362 (Pubitemid 32381981)
    • (2001) Investigative Ophthalmology and Visual Science , vol.42 , Issue.6 , pp. 1356-1362
    • Sparrow, J.R.1    Cai, B.2
  • 69
    • 62649135260 scopus 로고    scopus 로고
    • Complement activation by bisretinoid constituents of RPE lipofuscin
    • Zhou, J. et al. (2009) Complement activation by bisretinoid constituents of RPE lipofuscin. Investigative Ophthalmology and Visual Science 50, 1392-1399
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 1392-1399
    • Zhou, J.1
  • 70
    • 33646233454 scopus 로고    scopus 로고
    • Antioxidant properties of melanin in retinal pigment epithelial cells
    • Wang, Z., Dillon, J. and Gaillard, E.R. (2006) Antioxidant properties of melanin in retinal pigment epithelial cells. Photochemistry and Photobiology 82, 474-479
    • (2006) Photochemistry and Photobiology , vol.82 , pp. 474-479
    • Wang, Z.1    Dillon, J.2    Gaillard, E.R.3
  • 71
    • 0026695198 scopus 로고
    • Lipid peroxidation and antioxidant enzymatic systems in rat retina as a function of age
    • Castorina, C. et al. (1992) Lipid peroxidation and antioxidant enzymatic systems in rat retina as a function of age. Neurochemical Research 17, 599-604
    • (1992) Neurochemical Research , vol.17 , pp. 599-604
    • Castorina, C.1
  • 72
    • 33749017358 scopus 로고    scopus 로고
    • Effects of photodegradation on the physical and antioxidant properties of melanosomes isolated from retinal pigment epithelium
    • DOI 10.1562/2006-03-08-RA-836
    • Zareba, M. et al. (2006) Effects of photodegradation on the physical and antioxidant properties of melanosomes isolated from retinal pigment epithelium. Photochemistry and Photobiology 82, 1024-1029 (Pubitemid 44450187)
    • (2006) Photochemistry and Photobiology , vol.82 , Issue.4 , pp. 1024-1029
    • Zareba, M.1    Szewczyk, G.2    Sarna, T.3    Hong, L.4    Simon, J.D.5    Henry, M.M.6    Burke, J.M.7
  • 74
    • 33847417857 scopus 로고    scopus 로고
    • Experimental hypoxia in human eyes: Implications for ischaemic disease
    • DOI 10.1016/j.clinph.2006.12.012, PII S1388245706018682
    • Feigl, B., Stewart, I. and Brown, B. (2007) Experimental hypoxia in human eyes: implications for ischaemic disease. Clinical Neurophysiology 118, 887-895 (Pubitemid 46349833)
    • (2007) Clinical Neurophysiology , vol.118 , Issue.4 , pp. 887-895
    • Feigl, B.1    Stewart, I.2    Brown, B.3
  • 76
    • 0017897377 scopus 로고
    • The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium
    • Wing, G.L., Blanchard, G.C. and Weiter, J.J. (1978) The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium. Investigative Ophthalmology and Visual Science 17, 601-607 (Pubitemid 8364255)
    • (1978) Investigative Ophthalmology and Visual Science , vol.17 , Issue.7 , pp. 601-607
    • Wing, G.L.1    Blanchard, G.C.2    Weiter, J.J.3
  • 78
    • 0034071816 scopus 로고    scopus 로고
    • Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina
    • Rapp, L.M., Maple, S.S. and Choi, J.H. (2000) Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. Investigative Ophthalmology and Visual Science 41, 1200-1209 (Pubitemid 30187561)
    • (2000) Investigative Ophthalmology and Visual Science , vol.41 , Issue.5 , pp. 1200-1209
    • Rapp, L.M.1    Maple, S.S.2    Choi, J.H.3
  • 79
    • 70449644673 scopus 로고    scopus 로고
    • Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: Implications for age-related macular degeneration
    • Bertram, K.M. et al. (2009) Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration. American Journal of Physiology - Cell Physiology 297, C1200-C1210
    • (2009) American Journal of Physiology - Cell Physiology , vol.297
    • Bertram, K.M.1
  • 80
    • 33846923178 scopus 로고    scopus 로고
    • Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: Protection by (R)-alpha-lipoic acid
    • DOI 10.1167/iovs.06-0248
    • Jia, L. et al. (2007) Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid. Investigative Ophthalmology and Visual Science 48, 339-348 (Pubitemid 47251422)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.1 , pp. 339-348
    • Jia, L.1    Liu, Z.2    Sun, L.3    Miller, S.S.4    Ames, B.N.5    Cotman, C.W.6    Liu, J.7
  • 81
    • 69749099385 scopus 로고    scopus 로고
    • Cadmium-induced apoptotic death ofhuman retinal pigment epithelial cells is mediated by MAPK pathway
    • Kalariya, N.M. et al. (2009) Cadmium-induced apoptotic death ofhuman retinal pigment epithelial cells is mediated by MAPK pathway. Experimental Eye Research 89, 494-502
    • (2009) Experimental Eye Research , vol.89 , pp. 494-502
    • Kalariya, N.M.1
  • 83
    • 0029949607 scopus 로고    scopus 로고
    • Smoking and age-related maculopathy: The blue mountains eye study
    • Smith, W., Mitchell, P. and Leeder, S.R. (1996) Smoking and age-related maculopathy. The Blue Mountains Eye Study. Archives of Ophthalmology 114, 1518-1523 (Pubitemid 26406270)
    • (1996) Archives of Ophthalmology , vol.114 , Issue.12 , pp. 1518-1523
    • Smith, W.1    Mitchell, P.2    Leeder, S.R.3
  • 88
    • 0027534867 scopus 로고
    • Sunlight and age-related macular degeneration: The Beaver Dam Eye Study
    • Cruickshanks, K.J., Klein, R. and Klein, B.E. (1993) Sunlight and age-related macular degeneration. The Beaver Dam Eye Study. Archives of Ophthalmology 111, 514-518 (Pubitemid 23116899)
    • (1993) Archives of Ophthalmology , vol.111 , Issue.4 , pp. 514-518
    • Cruickshanks, K.J.1    Klein, R.2    Klein, B.F.K.3
  • 89
    • 0030920772 scopus 로고    scopus 로고
    • Sun exposure and age-related macular degeneration: An Australian case- control study
    • Darzins, P., Mitchell, P. and Heller, R.F. (1997) Sun exposure and age-related macular degeneration. An Australian case-control study. Ophthalmology 104, 770-776 (Pubitemid 27200873)
    • (1997) Ophthalmology , vol.104 , Issue.5 , pp. 770-776
    • Darzins, P.1    Mitchell, P.2    Heller, R.F.3
  • 90
    • 54049125065 scopus 로고    scopus 로고
    • Sunlight exposure, antioxidants, and age-related macular degeneration
    • Fletcher, A.E. et al. (2008) Sunlight exposure, antioxidants, and age-related macular degeneration. Archives of Ophthalmology 126, 1396-1403
    • (2008) Archives of Ophthalmology , vol.126 , pp. 1396-1403
    • Fletcher, A.E.1
  • 91
    • 63549133336 scopus 로고    scopus 로고
    • Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells
    • Bruban, J. et al. (2009) Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells. Aging Cell 8, 162-177
    • (2009) Aging Cell , vol.8 , pp. 162-177
    • Bruban, J.1
  • 93
    • 0032992736 scopus 로고    scopus 로고
    • Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration
    • DOI 10.1016/S0002-9394(99)00032-X, PII S000293949900032X
    • Frank, R.N., Amin, R.H. and Puklin, J.E. (1999) Antioxidant enzymes in the macular retinal pigment epithelium of eyes with neovascular age-related macular degeneration. American Journal of Ophthalmology 127, 694-709 (Pubitemid 29266746)
    • (1999) American Journal of Ophthalmology , vol.127 , Issue.6 , pp. 694-709
    • Frank, R.N.1    Amin, R.H.2    Puklin, J.E.3
  • 94
    • 33947383078 scopus 로고    scopus 로고
    • Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration
    • Decanini, A. et al. (2007) Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration. American Journal of Ophthalmology 143, 607-615
    • (2007) American Journal of Ophthalmology , vol.143 , pp. 607-615
    • Decanini, A.1
  • 95
    • 72449197100 scopus 로고    scopus 로고
    • Oxidative macromolecular damage in age-related macular degeneration
    • Totan, Y. et al. (2009) Oxidative macromolecular damage in age-related macular degeneration. Current Eye Research 34, 1089-1093
    • (2009) Current Eye Research , vol.34 , pp. 1089-1093
    • Totan, Y.1
  • 96
    • 0037343994 scopus 로고    scopus 로고
    • Nitric oxide and lipid peroxidation are increased and associated with decreased antioxidant enzyme activities in patients with age-related macular degeneration
    • DOI 10.1023/A:1022512402811
    • Evereklioglu, C. et al. (2003) Nitric oxide and lipid peroxidation are increased and associated with decreased antioxidant enzyme activities in patients with age-related macular degeneration. Documenta Ophthalmologica 106, 129-136 (Pubitemid 36355954)
    • (2003) Documenta Ophthalmologica , vol.106 , Issue.2 , pp. 129-136
    • Evereklioglu, C.1    Er, H.2    Doganay, S.3    Cekmen, M.4    Turkoz, Y.5    Otlu, B.6    Ozerol, E.7
  • 97
    • 0035670811 scopus 로고    scopus 로고
    • Plasma malondialdehyde and nitric oxide levels in age related macular degeneration
    • DOI 10.1136/bjo.85.12.1426
    • Totan, Y. et al. (2001) Plasma malondialdehyde and nitric oxide levels in age related macular degeneration. British Journal of Ophthalmology 85, 1426-1428 (Pubitemid 34032906)
    • (2001) British Journal of Ophthalmology , vol.85 , Issue.12 , pp. 1426-1428
    • Totan, Y.1    Cekic, O.2    Borazan, M.3    Uz, E.4    Sogut, S.5    Akyol, O.6
  • 98
    • 33745445207 scopus 로고    scopus 로고
    • Different plasma levels of vascular endothelial growth factor and nitric oxide between patients with choroidal and retinal neovascularization
    • Tsai, D.C. et al. (2006) Different plasma levels of vascular endothelial growth factor and nitric oxide between patients with choroidal and retinal neovascularization. Ophthalmologica 220, 246-251
    • (2006) Ophthalmologica , vol.220 , pp. 246-251
    • Tsai, D.C.1
  • 99
    • 33846345802 scopus 로고    scopus 로고
    • Elevated Serum Homocysteine, Low Serum Vitamin B12, Folate, and Age-related Macular Degeneration: The Blue Mountains Eye Study
    • DOI 10.1016/j.ajo.2006.08.032, PII S0002939406010166
    • Rochtchina, E. et al. (2007) Elevated serum homocysteine, low serum vitamin B12, folate, and age-related macular degeneration: the Blue Mountains Eye Study. American Journal of Ophthalmology 143, 344-346 (Pubitemid 46136142)
    • (2007) American Journal of Ophthalmology , vol.143 , Issue.2 , pp. 344-346
    • Rochtchina, E.1    Wang, J.J.2    Flood, V.M.3    Mitchell, P.4
  • 100
    • 29544443447 scopus 로고    scopus 로고
    • Evaluation of plasma homocysteine and risk of age-related macular degeneration
    • DOI 10.1016/j.ajo.2005.07.059, PII S0002939405008615
    • Seddon, J.M. et al. (2006) Evaluation of plasma homocysteine and risk of age-related macular degeneration. American Journal of Ophthalmology 141, 201-203 (Pubitemid 43016200)
    • (2006) American Journal of Ophthalmology , vol.141 , Issue.1 , pp. 201-203
    • Seddon, J.M.1    Gensler, G.2    Klein, M.L.3    Milton, R.C.4
  • 101
    • 33646264539 scopus 로고    scopus 로고
    • Plasma homocysteine and total thiol content in patients with exudative age-related macular degeneration
    • London
    • Coral, K. et al. (2006) Plasma homocysteine and total thiol content in patients with exudative age-related macular degeneration. Eye (London) 20, 203-207
    • (2006) Eye , vol.20 , pp. 203-207
    • Coral, K.1
  • 102
    • 63049137465 scopus 로고    scopus 로고
    • Decreased serum paraoxonase 1 activity and increased serum homocysteine and malondialdehyde levels in age-related macular degeneration
    • Ates, O. et al. (2009) Decreased serum paraoxonase 1 activity and increased serum homocysteine and malondialdehyde levels in age-related macular degeneration. Tohoku Journal of Experimental Medicine 217, 17-22
    • (2009) Tohoku Journal of Experimental Medicine , vol.217 , pp. 17-22
    • Ates, O.1
  • 104
    • 28344438168 scopus 로고    scopus 로고
    • Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration
    • DOI 10.1016/j.ophtha.2005.07.004, PII S016164200500895X
    • Vine, A.K. et al. (2005) Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration. Ophthalmology 112, 2076-2080 (Pubitemid 41720983)
    • (2005) Ophthalmology , vol.112 , Issue.12 , pp. 2076-2080
    • Vine, A.K.1    Stader, J.2    Branham, K.3    Musch, D.C.4    Swaroop, A.5
  • 105
    • 33646807420 scopus 로고    scopus 로고
    • Plasma homocysteine, vitamin B12 and folate levels in age-related macular degeneration
    • Kamburoglu, G. et al. (2006) Plasma homocysteine, vitamin B12 and folate levels in age-related macular degeneration. Graefes Archive for Clinical and Experimental Ophthalmology 244, 565-569
    • (2006) Graefes Archive for Clinical and Experimental Ophthalmology , vol.244 , pp. 565-569
    • Kamburoglu, G.1
  • 107
    • 0036784055 scopus 로고    scopus 로고
    • Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey
    • Heuberger, R.A. et al. (2002) Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey. American Journal of Clinical Nutrition 76, 897-902
    • (2002) American Journal of Clinical Nutrition , vol.76 , pp. 897-902
    • Heuberger, R.A.1
  • 109
    • 0027397668 scopus 로고
    • Antioxidant status and neovascular age-related macular degeneration
    • Eye Disease Case-Control Study Group
    • Eye Disease Case-Control Study Group. (1993) Antioxidant status and neovascular age-related macular degeneration. Archives of Ophthalmology 111, 104-109
    • (1993) Archives of Ophthalmology , vol.111 , pp. 104-109
  • 110
    • 67649992427 scopus 로고    scopus 로고
    • Serum antioxidants and age-related macular degeneration among older Japanese
    • Michikawa, T. et al. (2009) Serum antioxidants and age-related macular degeneration among older Japanese. Asia Pacific Journal of Clinical Nutrition 18, 1-7
    • (2009) Asia Pacific Journal of Clinical Nutrition , vol.18 , pp. 1-7
    • Michikawa, T.1
  • 111
    • 0028786898 scopus 로고
    • Serum antioxidants and age-related macular degeneration in a population-based case-control study
    • Mares-Perlman, J.A. et al. (1995) Serum antioxidants and age-related macular degeneration in a population-based case-control study. Archives of Ophthalmology 113, 1518-1523
    • (1995) Archives of Ophthalmology , vol.113 , pp. 1518-1523
    • Mares-Perlman, J.A.1
  • 114
    • 0027319714 scopus 로고
    • Antioxidant enzymes in RBCs as a biological index of age related macular degeneration
    • Prashar, S. et al. (1993) Antioxidant enzymes in RBCs as a biological index of age related macular degeneration. Acta Ophthalmologica 71, 214-218 (Pubitemid 23172674)
    • (1993) Acta Ophthalmologica , vol.71 , Issue.2 , pp. 214-218
    • Prashar, S.1    Pandav, S.S.2    Gupta, A.3    Nath, R.4
  • 115
    • 2342592640 scopus 로고    scopus 로고
    • Changes in antioxidant enzyme activity and malondialdehyde level in patients with age-related macular degeneration
    • DOI 10.1159/000076845
    • Yildirim, O. et al. (2004) Changes in antioxidant enzyme activity and malondialdehyde level in patients with age-related macular degeneration. Ophthalmologica 218, 202-206 (Pubitemid 38596587)
    • (2004) Ophthalmologica , vol.218 , Issue.3 , pp. 202-206
    • Yildirim, O.1    Ates, N.A.2    Tamer, L.3    Muslu, N.4    Ercan, B.5    Atik, U.6    Kanik, A.7
  • 118
    • 0030005581 scopus 로고    scopus 로고
    • Red blood cell antioxidant enzymes in age-related macular degeneration
    • De, La Paz, M.A., Zhang, J. and Fridovich, I. (1996) Red blood cell antioxidant enzymes in age-related macular degeneration. British Journal of Ophthalmology 80, 445-450
    • (1996) British Journal of Ophthalmology , vol.80 , pp. 445-450
    • De La Paz, M.A.1    Zhang, J.2    Fridovich, I.3
  • 119
    • 0033497487 scopus 로고    scopus 로고
    • Associations of antioxidant enzymes with cataract and age-related macular degeneration: The POLA study
    • Delcourt, C. et al. (1999) Associations of antioxidant enzymes with cataract and age-related macular degeneration. The POLA Study. Pathologies Oculaires Liees a l'Age. Ophthalmology 106, 215-222 (Pubitemid 30191615)
    • (1999) Ophthalmology , vol.106 , Issue.2 , pp. 215-222
    • Delcourt, C.1    Cristol, J.-P.2    Leger, C.L.3    Descomps, B.4    Papoz, L.5
  • 121
    • 58849137855 scopus 로고    scopus 로고
    • Daytime levels of melatonin in patients with age-related macular degeneration
    • Schmid-Kubista, K.E. et al. (2009) Daytime levels of melatonin in patients with age-related macular degeneration. Acta Ophthalmologica 87, 89-93
    • (2009) Acta Ophthalmologica , vol.87 , pp. 89-93
    • Schmid-Kubista, K.E.1
  • 122
    • 34249802348 scopus 로고    scopus 로고
    • Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration
    • Suzuki, M. et al. (2007) Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration. Molecular Vision 13, 772-778 (Pubitemid 46850583)
    • (2007) Molecular Vision , vol.13 , pp. 772-778
    • Suzuki, M.1    Kamei, M.2    Itabe, H.3    Yoneda, K.4    Bando, H.5    Kume, N.6    Tano, Y.7
  • 124
    • 0020655183 scopus 로고
    • Chemistry and metabolism of lipids in the vertebrate retina
    • Fliesler, S.J. and Anderson, R.E. (1983) Chemistry and metabolism of lipids in the vertebrate retina. Progress in Lipid Research 22, 79-131
    • (1983) Progress in Lipid Research , vol.22 , pp. 79-131
    • Fliesler, S.J.1    Anderson, R.E.2
  • 125
    • 0038627633 scopus 로고    scopus 로고
    • Oxidatively truncated docosahexaenoate phospholipids: Total synthesis, generation, and peptide adduction chemistry
    • Gu, X. et al. (2003) Oxidatively truncated docosahexaenoate phospholipids: total synthesis, generation, and peptide adduction chemistry. Journal of Organic Chemistry 68, 3749-3761 (Pubitemid 36576624)
    • (2003) Journal of Organic Chemistry , vol.68 , Issue.10 , pp. 3749-3761
    • Gu, X.1    Sun, M.2    Gugiu, B.3    Hazen, S.4    Crabb, J.W.5    Salomon, R.G.6
  • 128
    • 67650519801 scopus 로고    scopus 로고
    • Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers
    • Gu, J. et al. (2009) Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers. Molecular and Cellular Proteomics 8, 1338-1349
    • (2009) Molecular and Cellular Proteomics , vol.8 , pp. 1338-1349
    • Gu, J.1
  • 129
    • 0034896106 scopus 로고    scopus 로고
    • Paraoxonase gene polymorphisms and plasma oxidized low-density lipoprotein level as possible risk factors for exudative age-related macular degeneration
    • DOI 10.1016/S0002-9394(01)00975-8, PII S0002939401009758
    • Ikeda, T. et al. (2001) Paraoxonase gene polymorphisms and plasma oxidized low-density lipoprotein level as possible risk factors for exudative age-related macular degeneration. American Journal of Ophthalmology 132, 191-195 (Pubitemid 32706513)
    • (2001) American Journal of Ophthalmology , vol.132 , Issue.2 , pp. 191-195
    • Ikeda, T.1    Obayashi, H.2    Hasegawa, G.3    Nakamura, N.4    Yoshikawa, T.5    Imamura, Y.6    Koizumi, K.7    Kinoshita, S.8
  • 130
  • 132
    • 24044471309 scopus 로고    scopus 로고
    • Superoxide dismutases and their impact upon human health
    • DOI 10.1016/j.mam.2005.07.006, PII S0098299705000361
    • Johnson, F. and Giulivi, C. (2005) Superoxide dismutases and their impact upon human health. Molecular Aspects of Medicine 26, 340-352 (Pubitemid 41225357)
    • (2005) Molecular Aspects of Medicine , vol.26 , Issue.4-5 SPEC. ISS. , pp. 340-352
    • Johnson, F.1    Giulivi, C.2
  • 133
    • 0040920369 scopus 로고    scopus 로고
    • McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information, (Bethesda, MD). World Wide Web
    • Online Mendelian Inheritance in Man, OMIM (TM). McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information, National Library of Medicine (Bethesda, MD). World Wide Web URL:http://www.ncbi.nlm.nih.gov/omim/
    • Online Mendelian Inheritance in Man, OMIM (TM)
  • 134
    • 0034533059 scopus 로고    scopus 로고
    • Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration
    • DOI 10.1016/S0002-9394(00)00552-3, PII S0002939400005523
    • Kimura, K. et al. (2000) Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration. American Journal of Ophthalmology 130, 769-773 (Pubitemid 32000858)
    • (2000) American Journal of Ophthalmology , vol.130 , Issue.6 , pp. 769-773
    • Kimura, K.1    Isashiki, Y.2    Sonoda, S.3    Kakiuchi-Matsumoto, T.4    Ohba, N.5
  • 135
    • 45249084304 scopus 로고    scopus 로고
    • Manganese superoxide dismutase gene (SOD2) polymorphism and exudative age-related macular degeneration in the Japanese population
    • Gotoh, N. et al. (2008) Manganese superoxide dismutase gene (SOD2) polymorphism and exudative age-related macular degeneration in the Japanese population. American Journal of Ophthalmology 146, 146-147
    • (2008) American Journal of Ophthalmology , vol.146 , pp. 146-147
    • Gotoh, N.1
  • 136
    • 70349245183 scopus 로고    scopus 로고
    • SOD2 gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
    • Kondo, N. et al. (2009) SOD2 gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. Molecular Vision 15, 1819-1826
    • (2009) Molecular Vision , vol.15 , pp. 1819-1826
    • Kondo, N.1
  • 138
    • 64549116363 scopus 로고    scopus 로고
    • Oxidative stress promotes ocular neovascularization
    • Dong, A. et al. (2009) Oxidative stress promotes ocular neovascularization. Journal of Cellular Physiology 219, 544-552
    • (2009) Journal of Cellular Physiology , vol.219 , pp. 544-552
    • Dong, A.1
  • 141
    • 27244451344 scopus 로고    scopus 로고
    • SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: Implications for age-related macular degeneration
    • DOI 10.1167/iovs.05-0344
    • Kasahara, E. et al. (2005) SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration. Investigative Ophthalmology and Visual Science 46, 3426-3434 (Pubitemid 44264334)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.9 , pp. 3426-3434
    • Kasahara, E.1    Lin, L.-R.2    Ho, Y.-S.3    Reddy, V.N.4
  • 142
    • 60749137157 scopus 로고    scopus 로고
    • Increased expression of glutathione peroxidase 4 strongly protects retina from oxidative damage
    • Lu, L. et al. (2009) Increased expression of glutathione peroxidase 4 strongly protects retina from oxidative damage. Antioxidants and Redox Signaling 11, 715-724
    • (2009) Antioxidants and Redox Signaling , vol.11 , pp. 715-724
    • Lu, L.1
  • 144
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • DOI 10.1093/hmg/ddi353
    • Rivera, A. et al. (2005) Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Human Molecular Genetics 14, 3227-3236 (Pubitemid 41631297)
    • (2005) Human Molecular Genetics , vol.14 , Issue.21 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3    Keilhauer, C.N.4    Lichtner, P.5    Meitinger, T.6    Weber, B.H.F.7
  • 146
    • 67649998898 scopus 로고    scopus 로고
    • Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria
    • Wang, G. et al. (2009) Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria. Investigative Ophthalmology and Visual Science 50, 3084-3090
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 3084-3090
    • Wang, G.1
  • 147
    • 33646070308 scopus 로고    scopus 로고
    • Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration
    • Schmidt, S. et al. (2006) Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. American Journal of Human Genetics 78, 852-864
    • (2006) American Journal of Human Genetics , vol.78 , pp. 852-864
    • Schmidt, S.1
  • 149
    • 65749108269 scopus 로고    scopus 로고
    • Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration
    • SanGiovanni, J.P. et al. (2009) Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration. PLoS One 4, e5508
    • (2009) PLoS One , vol.4
    • SanGiovanni, J.P.1
  • 150
    • 70350238360 scopus 로고    scopus 로고
    • Unraveling a multifactorial late-onset disease: From genetic susceptibility to disease mechanisms for age-related macular degeneration
    • Swaroop, A. et al. (2009) Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annual Review of Genomics and Human Genetics 10, 19-43
    • (2009) Annual Review of Genomics and Human Genetics , vol.10 , pp. 19-43
    • Swaroop, A.1
  • 155
    • 33645419787 scopus 로고    scopus 로고
    • Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
    • Gold, B. et al. (2006) Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nature Genetics 38, 458-462
    • (2006) Nature Genetics , vol.38 , pp. 458-462
    • Gold, B.1
  • 156
    • 77449122005 scopus 로고    scopus 로고
    • Support for the involvement of complement factor I in age-related macular degeneration
    • Ennis, S. et al. (2009) Support for the involvement of complement factor I in age-related macular degeneration. European Journal of Human Genetics 18, 15-16
    • (2009) European Journal of Human Genetics , vol.18 , pp. 15-16
    • Ennis, S.1
  • 157
    • 57649215855 scopus 로고    scopus 로고
    • Variation near complement factor I is associated with risk of advanced AMD
    • Fagerness, J.A. et al. (2009) Variation near complement factor I is associated with risk of advanced AMD. European Journal of Human Genetics 17, 100-104
    • (2009) European Journal of Human Genetics , vol.17 , pp. 100-104
    • Fagerness, J.A.1
  • 159
    • 33749123246 scopus 로고    scopus 로고
    • A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
    • DOI 10.1038/ng1890, PII NG1890
    • Hughes, A.E. et al. (2006) A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration. Nature Genetics 38, 1173-1177 (Pubitemid 44470363)
    • (2006) Nature Genetics , vol.38 , Issue.10 , pp. 1173-1177
    • Hughes, A.E.1    Orr, N.2    Esfandiary, H.3    Diaz-Torres, M.4    Goodship, T.5    Chakravarthy, U.6
  • 160
    • 56249123595 scopus 로고    scopus 로고
    • Association between the SERPING1 gene and age-related macular degeneration: A two-stage case-control study
    • Ennis, S. et al. (2008) Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study. Lancet 372, 1828-1834
    • (2008) Lancet , vol.372 , pp. 1828-1834
    • Ennis, S.1
  • 162
    • 29744442338 scopus 로고    scopus 로고
    • Smoking and age related macular degeneration: The number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation
    • DOI 10.1136/bjo.2005.073643
    • Khan, J.C. et al. (2006) Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. British Journal of Ophthalmology 90, 75-80 (Pubitemid 43029901)
    • (2006) British Journal of Ophthalmology , vol.90 , Issue.1 , pp. 75-80
    • Khan, J.C.1    Thurlby, D.A.2    Shahid, H.3    Clayton, D.G.4    Yates, J.R.W.5    Bradley, M.6    Moore, A.T.7    Bird, A.C.8
  • 163
    • 0035879765 scopus 로고    scopus 로고
    • Lipofuscin-formation in retinal pigment epithelial cells is reduced by antioxidants
    • DOI 10.1016/S0891-5849(01)00573-1, PII S0891584901005731
    • Sundelin, S.P. and Nilsson, S.E. (2001) Lipofuscinformation in retinal pigment epithelial cells is reduced by antioxidants. Free Radical Biology and Medicine 31, 217-225 (Pubitemid 32607588)
    • (2001) Free Radical Biology and Medicine , vol.31 , Issue.2 , pp. 217-225
    • Sundelin, S.P.1    Nilsson, S.E.G.2
  • 164
    • 35348966298 scopus 로고    scopus 로고
    • Dietary antioxidants and primary prevention of age related macular degeneration: Systematic reviewand meta-analysis
    • Chong, E.W. et al. (2007) Dietary antioxidants and primary prevention of age related macular degeneration: systematic reviewand meta-analysis. BMJ 335, 755-758
    • (2007) BMJ , vol.335 , pp. 755-758
    • Chong, E.W.1
  • 165
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
    • Age-Related Eye Disease Study Research Group. [Erratum appears in Arch Ophthalmol. 2008 Sep;126(9):1251]
    • Age-Related Eye Disease Study Research Group. (2001) A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8 [Erratum appears in Arch Ophthalmol. 2008 Sep;126(9):1251]. Archives of Ophthalmology 119, 1417-1436
    • (2001) Archives of Ophthalmology , vol.119 , pp. 1417-1436
  • 166
    • 84862739107 scopus 로고    scopus 로고
    • Vanderbilt University, USA. ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, [cited 2010 July 07], available from: NLM Identifier: NCT00668213
    • Vanderbilt University, USA. Antioxidant systems and age-related macular degeneration. In ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, 2000 [cited 2010 July 07], available from: http://clinicaltrials.gov/ct2/show/NCT00668213. NLM Identifier: NCT00668213
    • (2000) Antioxidant Systems and Age-related Macular Degeneration
  • 168
    • 84862752237 scopus 로고    scopus 로고
    • National Eye Institute (NEI). ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, [cited 2010 March 20], available from: NLM Identifier: NCT00345176
    • National Eye Institute (NEI). Age-related eye disease study 2 (AREDS2). In ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, 2000 [cited 2010 March 20], available from: http://clinicaltrials.gov/ ct2/show/NCT00345176. NLM Identifier: NCT00345176
    • (2000) Age-related Eye Disease Study 2 (AREDS2)
  • 169
    • 84862729099 scopus 로고    scopus 로고
    • Centre de Recherche en Nutrition Humaine Rhone-Alpe, France. ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, [cited 2010 July 07], available from: NLM Identifier: NCT00800995
    • Centre de Recherche en Nutrition Humaine Rhone-Alpe, France. Superoxide dismutase (SOD) as antioxidant treatment of age related macular degeneration (ARMD). In ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, 2000 [cited 2010 July 07], available from: http://clinicaltrials.gov/ct2/show/NCT00800995. NLM Identifier: NCT00800995
    • (2000) Superoxide Dismutase (SOD) As Antioxidant Treatment of Age Related Macular Degeneration (ARMD)
  • 170
    • 33751184363 scopus 로고    scopus 로고
    • Oxidative-induced retinal degeneration is attenuated by epigallocatechin gallate
    • DOI 10.1016/j.brainres.2006.09.067, PII S0006899306028460
    • Zhang, B. and Osborne, N.N. (2006) Oxidative-induced retinal degeneration is attenuated by epigallocatechin gallate. Brain Research 1124, 176-187 (Pubitemid 44779557)
    • (2006) Brain Research , vol.1124 , Issue.1 , pp. 176-187
    • Zhang, B.1    Osborne, N.N.2
  • 171
    • 84862737735 scopus 로고    scopus 로고
    • National Eye Institute (NEI), USA. ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, [cited 2010 July 07], available from NLM Identifier: NCT00718653
    • National Eye Institute (NEI), USA. Effects of antioxidants on human macular pigments. In ClinicalTrials.gov [Internet], National Library of Medicine (US), Bethesda, MD, USA, 2000 [cited 2010 July 07], available from http://clinicaltrials.gov/ct2/show/NCT00718653. NLM Identifier: NCT00718653
    • (2000) Effects of Antioxidants on Human Macular Pigments
  • 172
    • 77952877327 scopus 로고    scopus 로고
    • Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adults
    • Li, L. et al. (2010) Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adults. Journal of Nutritional Biochemistry 21, 544-549
    • (2010) Journal of Nutritional Biochemistry , vol.21 , pp. 544-549
    • Li, L.1
  • 173
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane)
    • corrected
    • Singh, S. and Aggarwal, B.B. (1995) Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. Journal of Biological Chemistry 270, 24995-25000
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 175
    • 0032991568 scopus 로고    scopus 로고
    • Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages
    • Abe, Y., Hashimoto, S. and Horie, T. (1999) Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacological Research 39, 41-47
    • (1999) Pharmacological Research , vol.39 , pp. 41-47
    • Abe, Y.1    Hashimoto, S.2    Horie, T.3
  • 176
    • 59249104565 scopus 로고    scopus 로고
    • Curcumin protects retinal cells from light-and oxidant stress-induced cell death
    • Mandal, M.N. et al. (2009) Curcumin protects retinal cells from light-and oxidant stress-induced cell death. Free Radical Biology and Medicine 46, 672-679
    • (2009) Free Radical Biology and Medicine , vol.46 , pp. 672-679
    • Mandal, M.N.1
  • 177
    • 33845893468 scopus 로고    scopus 로고
    • Ginkgo biloba - An appraisal
    • [Review] 44 Refs
    • Dubey, A.K. et al. (2004) Ginkgo biloba - an appraisal. [Review] [44 Refs]. Kathmandu University Medical Journal 2, 225-229
    • (2004) Kathmandu University Medical Journal , vol.2 , pp. 225-229
    • Dubey, A.K.1
  • 178
    • 13444269361 scopus 로고    scopus 로고
    • Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition
    • DOI 10.1016/j.cbi.2004.11.003
    • King, R.E., Kent, K.D. and Bomser, J.A. (2005) Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition. Chemico-Biological Interactions 151, 143-149 (Pubitemid 40208564)
    • (2005) Chemico-Biological Interactions , vol.151 , Issue.2 , pp. 143-149
    • King, R.E.1    Kent, K.D.2    Bomser, J.A.3
  • 179
    • 77950189559 scopus 로고    scopus 로고
    • NF-kappaB inhibitory action of resveratrol: A probable mechanism of neuroprotection in experimental diabetic neuropathy
    • Kumar, A. and Sharma, S.S. (2010) NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy. Biochemical and Biophysical Research Communications 394, 360-365
    • (2010) Biochemical and Biophysical Research Communications , vol.394 , pp. 360-365
    • Kumar, A.1    Sharma, S.S.2
  • 180
    • 45549092748 scopus 로고    scopus 로고
    • The protective effect of quercetin against oxidative stress in the human RPE in vitro
    • Kook, D. et al. (2008) The protective effect of quercetin against oxidative stress in the human RPE in vitro. Investigative Ophthalmology Visual Science 49, 1712-1720
    • (2008) Investigative Ophthalmology Visual Science , vol.49 , pp. 1712-1720
    • Kook, D.1
  • 182
    • 79955056247 scopus 로고    scopus 로고
    • Treatment of geographic atrophy by the topical administration of OT-551: Results of a phase II clinical trial
    • 2010 Jun 23 [Epub ahead of print]
    • Wong, W.T. et al. (2010) Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial. Investigative Ophthalmology Visual Science 2010 Jun 23 [Epub ahead of print]
    • (2010) Investigative Ophthalmology Visual Science
    • Wong, W.T.1
  • 183
    • 73849095427 scopus 로고    scopus 로고
    • The nuclear signaling of NF-kappaB: Current knowledge, new insights, and future perspectives
    • Wan, F. and Lenardo, M.J. (2010) The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives. Cell Research 20, 24-33
    • (2010) Cell Research , vol.20 , pp. 24-33
    • Wan, F.1    Lenardo, M.J.2
  • 184
    • 33750475618 scopus 로고    scopus 로고
    • Current insights into the regulation of programmed cell death by NF-kappaB
    • DOI 10.1038/sj.onc.1209938, PII 1209938
    • Dutta, J. et al. (2006) Current insights into the regulation of programmed cell death by NF-kappaB. Oncogene 25, 6800-6816 (Pubitemid 44657853)
    • (2006) Oncogene , vol.25 , Issue.51 , pp. 6800-6816
    • Dutta, J.1    Fan, Y.2    Gupta, N.3    Fan, G.4    Gelinas, C.5
  • 187
    • 0035584857 scopus 로고    scopus 로고
    • Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
    • DOI 10.1016/S0891-5849(01)00724-9, PII S0891584901007249
    • Nordberg, J. and Arner, E.S. (2001) Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radical Biology and Medicine 31, 1287-1312 (Pubitemid 33145299)
    • (2001) Free Radical Biology and Medicine , vol.31 , Issue.11 , pp. 1287-1312
    • Nordberg, J.1    Arner, E.S.J.2
  • 188
    • 33847746679 scopus 로고    scopus 로고
    • Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: Implications for diseases in the cardiovascular system
    • Berndt, C., Lillig, C.H. and Holmgren, A. (2007) Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. AJP - Heart and Circulatory Physiology 292, H1227-H1236
    • (2007) AJP - Heart and Circulatory Physiology , vol.292
    • Berndt, C.1    Lillig, C.H.2    Holmgren, A.3
  • 189
    • 46449117295 scopus 로고    scopus 로고
    • Thioredoxin-like 6 protects retinal cell line from photooxidative damage by upregulating NF-kappaB activity
    • Wang, X.W. et al. (2008) Thioredoxin-like 6 protects retinal cell line from photooxidative damage by upregulating NF-kappaB activity. Free Radical Biology and Medicine 45, 336-344
    • (2008) Free Radical Biology and Medicine , vol.45 , pp. 336-344
    • Wang, X.W.1
  • 191
    • 33751178410 scopus 로고    scopus 로고
    • The thioredoxin system in cancer
    • DOI 10.1016/j.semcancer.2006.10.009, PII S1044579X06001027
    • Arnér, E.S.J. and Holmgren, A. (2006) The thioredoxin system in cancer. Seminars in Cancer Biology 16, 420-426 (Pubitemid 44780139)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.6 , pp. 420-426
    • Arner, E.S.J.1    Holmgren, A.2
  • 192
    • 0033581704 scopus 로고    scopus 로고
    • The p66shc adaptor protein controls oxidative stress response and life span in mammals
    • Migliaccio, E. et al. (1999) The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402, 309-313
    • (1999) Nature , vol.402 , pp. 309-313
    • Migliaccio, E.1
  • 194
    • 77952569653 scopus 로고    scopus 로고
    • Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia
    • Capitani, N. et al. (2010) Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia. Blood 115, 3726-3736
    • (2010) Blood , vol.115 , pp. 3726-3736
    • Capitani, N.1
  • 195
    • 54849175900 scopus 로고    scopus 로고
    • Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice
    • Li, Q. et al. (2008) Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice. Molecular Therapy: The Journal of the American Society of Gene Therapy 16, 1688-1694
    • (2008) Molecular Therapy: The Journal of the American Society of Gene Therapy , vol.16 , pp. 1688-1694
    • Li, Q.1
  • 196
    • 73349128447 scopus 로고    scopus 로고
    • Delivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature
    • Chen, B. et al. (2009) Delivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature. Investigative Ophthalmology and Visual Science 50, 5587-5595
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 5587-5595
    • Chen, B.1
  • 197
    • 5644298299 scopus 로고    scopus 로고
    • Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress
    • DOI 10.1089/hum.2004.15.960
    • Rex, T.S. et al. (2004) Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress. Human Gene Therapy 15, 960-967 (Pubitemid 39372572)
    • (2004) Human Gene Therapy , vol.15 , Issue.10 , pp. 960-967
    • Rex, T.S.1    Tsui, I.2    Hahn, P.3    Maguire, A.M.4    Duan, D.5    Bennett, J.6    Dunaief, J.L.7
  • 198
    • 3142721782 scopus 로고    scopus 로고
    • Induction of phase 2 genes by sulforaphane protects, retinal pigment epithelial cells against photooxidative damage
    • DOI 10.1073/pnas.0403886101
    • Gao, X. and Talalay, P. (2004) Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proceedings of the National Academy of Sciences of the United States of America 101, 10446-10451 (Pubitemid 38924945)
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , Issue.28 , pp. 10446-10451
    • Gao, X.1    Talalay, P.2
  • 199
    • 47249120767 scopus 로고    scopus 로고
    • Demonstration by redox fluorometry that sulforaphane protects retinal pigment epithelial cells against oxidative stress
    • del, V.C. et al. (2008) Demonstration by redox fluorometry that sulforaphane protects retinal pigment epithelial cells against oxidative stress. Investigative Ophthalmology and Visual Science 49, 2606-2612
    • (2008) Investigative Ophthalmology and Visual Science , vol.49 , pp. 2606-2612
    • Del, V.C.1
  • 200
    • 33947178903 scopus 로고    scopus 로고
    • Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway
    • Liu, X.P. et al. (2007) Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway. Life Sciences 80, 1586-1591
    • (2007) Life Sciences , vol.80 , pp. 1586-1591
    • Liu, X.P.1
  • 201
    • 0034490852 scopus 로고    scopus 로고
    • Chemoprotection against cancer by induction of phase 2 enzymes
    • Talalay, P. (2000) Chemoprotection against cancer by induction of phase 2 enzymes. Biofactors 12, 5-11
    • (2000) Biofactors , vol.12 , pp. 5-11
    • Talalay, P.1
  • 202
    • 0038378322 scopus 로고    scopus 로고
    • Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis
    • DOI 10.1016/S0065-2571(02)00038-9
    • Talalay, P., Dinkova-Kostova, A.T. and Holtzclaw, W.D. (2003) Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis. Advances in Enzyme Regulation 43, 121-134 (Pubitemid 36872827)
    • (2003) Advances in Enzyme Regulation , vol.43 , pp. 121-134
    • Talalay, P.1    Dinkova-Kostova, A.T.2    Holtzclaw, W.D.3
  • 203
    • 35248872920 scopus 로고    scopus 로고
    • Increased expression of glial cell line-derived neurotrophic factor protects against oxidative damage-induced retinal degeneration
    • DOI 10.1111/j.1471-4159.2007.04839.x
    • Dong, A. et al. (2007) Increased expression of glial cell line-derived neurotrophic factor protects against oxidative damage-induced retinal degeneration. Journal of Neurochemistry 103, 1041-1052 (Pubitemid 47568739)
    • (2007) Journal of Neurochemistry , vol.103 , Issue.3 , pp. 1041-1052
    • Dong, A.1    Shen, J.2    Krause, M.3    Hackett, S.F.4    Campochiaro, P.A.5
  • 204
  • 205
    • 34250367839 scopus 로고    scopus 로고
    • Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides
    • Chen, J. et al. (2006) Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nature Nanotechnology 1, 142-150
    • (2006) Nature Nanotechnology , vol.1 , pp. 142-150
    • Chen, J.1
  • 206
    • 34249930365 scopus 로고    scopus 로고
    • Flupirtine attenuates sodium nitroprusside-induced damage to retinal photoreceptors, in situ
    • DOI 10.1016/j.brainresbull.2007.04.002, PII S036192300700127X
    • Fawcett, R.J. and Osborne, N.N. (2007) Flupirtine attenuates sodium nitroprusside-induced damage to retinal photoreceptors, in situ. Brain Research Bulletin 73, 278-288 (Pubitemid 46880064)
    • (2007) Brain Research Bulletin , vol.73 , Issue.4-6 , pp. 278-288
    • Fawcett, R.J.1    Osborne, N.N.2
  • 207
    • 77957221943 scopus 로고    scopus 로고
    • Synthetic triterpenoids attenuate cytotoxic retinal injury: Cross-talk between Nrf2 and PI3 K/AKT signaling through inhibition of the lipid phosphatase PTEN
    • Pitha-Rowe, I. et al. (2009) Synthetic triterpenoids attenuate cytotoxic retinal injury: cross-talk between Nrf2 and PI3 K/AKT signaling through inhibition of the lipid phosphatase PTEN. Investigative Ophthalmology and Visual Science 50, 5339-5347
    • (2009) Investigative Ophthalmology and Visual Science , vol.50 , pp. 5339-5347
    • Pitha-Rowe, I.1
  • 208
    • 73349109760 scopus 로고    scopus 로고
    • Triterpenoids as new promising anticancer drugs
    • Petronelli, A., Pannitteri, G. and Testa, U. (2009) Triterpenoids as new promising anticancer drugs. Anticancer Drugs 20, 880-892
    • (2009) Anticancer Drugs , vol.20 , pp. 880-892
    • Petronelli, A.1    Pannitteri, G.2    Testa, U.3
  • 209
    • 71749104726 scopus 로고    scopus 로고
    • Cannabinoid receptors in brain: Pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications
    • Onaivi, E.S. (2009) Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications. International Review of Neurobiology 88, 335-369
    • (2009) International Review of Neurobiology , vol.88 , pp. 335-369
    • Onaivi, E.S.1
  • 210
    • 33750452664 scopus 로고    scopus 로고
    • Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration
    • DOI 10.1016/j.plefa.2006.08.002, PII S0952327806001505
    • Matias, I. et al. (2006) Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. Prostaglandins, Leukotrienes, and Essential Fatty Acids 75, 413-418 (Pubitemid 44648737)
    • (2006) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.75 , Issue.6 , pp. 413-418
    • Matias, I.1    Wang, J.W.2    Moriello, A.S.3    Nieves, A.4    Woodward, D.F.5    Di, M.V.6
  • 211
    • 67650095540 scopus 로고    scopus 로고
    • Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells
    • Wei, Y., Wang, X. and Wang, L. (2009) Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells. Molecular Vision 15, 1243-1251
    • (2009) Molecular Vision , vol.15 , pp. 1243-1251
    • Wei, Y.1    Wang, X.2    Wang, L.3
  • 212
    • 70449699754 scopus 로고    scopus 로고
    • Cannabinoids for clinicians: The rise and fall of the cannabinoid antagonists
    • Butler, H. and Korbonits, M. (2009) Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists. European Journal of Endocrinology 161, 655-662
    • (2009) European Journal of Endocrinology , vol.161 , pp. 655-662
    • Butler, H.1    Korbonits, M.2
  • 213
    • 0031755934 scopus 로고    scopus 로고
    • Biology of erythropoietin
    • Lacombe, C. and Mayeux, P. (1998) Biology of erythropoietin. Haematologica 83, 724-732 (Pubitemid 28492155)
    • (1998) Haematologica , vol.83 , Issue.8 , pp. 724-732
    • Lacombe, C.1    Mayeux, P.2
  • 215
    • 69249220420 scopus 로고    scopus 로고
    • Neuroprotective role of erythropoietin by antiapoptosis in the retina
    • Chung, H. et al. (2009) Neuroprotective role of erythropoietin by antiapoptosis in the retina. Journal of Neuroscience Research 87, 2365-2374
    • (2009) Journal of Neuroscience Research , vol.87 , pp. 2365-2374
    • Chung, H.1
  • 216
    • 77149158168 scopus 로고    scopus 로고
    • Erythropoetin receptor expression in the human diabetic retina
    • Shah, S.S., Tsang, S.H. and Mahajan, V.B. (2009) Erythropoetin receptor expression in the human diabetic retina. BMC Research Notes 2, 234
    • (2009) BMC Research Notes , vol.2 , pp. 234
    • Shah, S.S.1    Tsang, S.H.2    Mahajan, V.B.3
  • 217
    • 63049096543 scopus 로고    scopus 로고
    • Erythropoietin protects retinal pigment epithelial cells from oxidative damage
    • Wang, Z.Y. et al. (2009) Erythropoietin protects retinal pigment epithelial cells from oxidative damage. Free Radical Biology and Medicine 46, 1032-1041
    • (2009) Free Radical Biology and Medicine , vol.46 , pp. 1032-1041
    • Wang, Z.Y.1
  • 218
    • 70349445409 scopus 로고    scopus 로고
    • Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse
    • Rex, T.S. et al. (2009) Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse. Experimental Eye Research 89, 735-740
    • (2009) Experimental Eye Research , vol.89 , pp. 735-740
    • Rex, T.S.1
  • 220
    • 34249000287 scopus 로고    scopus 로고
    • Dietary restriction in aging nonhuman primates
    • Mattison, J.A. et al. (2007) Dietary restriction in aging nonhuman primates. Interdiscip Top Gerontol 35, 137-158
    • (2007) Interdiscip Top Gerontol , vol.35 , pp. 137-158
    • Mattison, J.A.1
  • 221
    • 0042925473 scopus 로고    scopus 로고
    • Caloric restriction retards age-related changes in rat retina
    • DOI 10.1016/j.bbrc.2003.08.020
    • Li, D., Sun, F. and Wang, K. (2003) Caloric restriction retards age-related changes in rat retina. Biochemical and Biophysical Research Communications 309, 457-463 (Pubitemid 37025912)
    • (2003) Biochemical and Biophysical Research Communications , vol.309 , Issue.2 , pp. 457-463
    • Li, D.1    Sun, F.2    Wang, K.3
  • 222
    • 51649121907 scopus 로고    scopus 로고
    • Drusenoid maculopathy in rhesus monkeys (Macaca mulatta): Effects of age and gender
    • Gouras, P. et al. (2008) Drusenoid maculopathy in rhesus monkeys (Macaca mulatta): effects of age and gender. Graefes Archive for Clinical and Experimental Ophthalmology 246, 1395-1402
    • (2008) Graefes Archive for Clinical and Experimental Ophthalmology , vol.246 , pp. 1395-1402
    • Gouras, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.