Increased expression of angiogenic growth factors in age-related maculopathy

British Journal of Ophthalmology

Volumn 81, Issue 2, 1997, Pages 154-162

  Kliffen, Mike ^a   Sharma, Hari S ^a   Mooy, Cornelia M ^a   Kerkvliet, Sonja ^a   De Jong, Paulus T V M ^b  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ADULT; AGED; AGING; ARTICLE; BLINDNESS; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; PATHOGENESIS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA MACULA DEGENERATION; RETINA MACULOPATHY; RETINA NEOVASCULARIZATION;

EID: 0031050126     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.81.2.154     Document Type: Article

References (54)

1. Green WK, Enger C. Age-related macular degeneration histopathologic studies. The 1992 Lorenz E Zimmerman Lecture. Ophthalmology 1993;100:1519-35.
2. Kliffen M, van der Schaft TL, Mooy CM, de Jong PTVM. Morphologic changes in age-related maculopathy. Microsc Res Tech 1996; (in press).
3. Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis MD, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. Surv Ophthalmol 1995;39: 367-74.
4. Vingerling JR, Dielemans I, Hofman A, Grobbee DE, Hijmering M, Kramer CF, et al. Prevalence of age-related maculopathy in the Rotterdam study. Ophthalmology 1995; 102:205-10.
5. Klein R, Klein BEK, Linton KLP. Prevalence of age-related maculopathy. The Beaver Dam Eye Study. Ophthalmology 1992;99:933-43.
6. Sarks JP, Sarks SH, Killingsworth MC. Evolution of geographic atrophy of the retinal pigment epithelium. Eye 1988;2:552-77.
7. Bressler NM, Bressler SB, Fine SL. Age-related macular degeneration. Surv Ophthalmol 1988;32:375-413.
8. Folkman J, Shing Y. Angiogenesis. [Review] J Biol Chem 1992;267:10931-4.
9. Ferrara N, Heinsohn H, Walder CE, Bunting S, Thomas GR. The regulation of blood vessel growth by vascular endothelial growth factor. [Review] Ann NY Acad Sci 1995;752:246-56.
10. Sporn MB, Roberts AB, Wakefield LM, de Crombrugghe B. Some recent advances in the chemistry and biology of transforming growth factor-beta. [Review] J Cell Biol 1987; 105:1039-15.
11. Amin R, Puklin JE, Frank RN. Growth factor localization in choroidal neovascular membranes of age-related macular degeneration. Invest Ophthalmol Vis Sci 1994;35:3178-88.
12. Sivalingam A, Kenney J, Brown GC, Benson WE, Donoso L. Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol 1990;108:869-72.
13. Reddy MR, Zamora RL, Kaplan HJ. Distribution of growth factors in subfoveal neovascular membranes in age-related macular degeneration and presumed ocular histoplasmosis sysndrome. Am J Ophthalmol 1995;120:291-301.
14. Yoshida M, Tanihara H, Yoshimura N. Platelet-derived growth factor gene expression in cultured human retinal pigment epithelial cells. Biochem Biophys Res Commun 1992;189:66-71.
15. Leschey KH, Hackett SF, Singer JH, Campochiaro PA. Growth factor responsiveness of human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1990;31:839-46.
16. Tanihara H, Yoshida M, Matsumoto M, Yoshimura N. Identification of transforming growth factor-beta expressed in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1993;34:413-9.
17. Ocrant I, Fay CT, Parmelee JT. Expression of insulin and insulin-like growth factor receptors and binding proteins by retinal pigment epithelium. Exp Eye Res 1991;52:581-9.
18. Ishigooka H, Aotaki-Keen AE, Hjelmeland LM. Subcellular localization of bFGF in human retinal pigment epithelium in vitro. Exp Eye Res 1992;55:203-14.
19. Campochiaro PA, Sugg R, Grotendorst G, Hjelmeland LM. Retinal pigment epithelial cells produce PDGF-like proteins and secrete them into their media. Exp Eye Res 1989;49:217-27.
20. Adamis AP, Shima DT, Yeo KT, Yeo TK, Brown LF, Berse B, et al. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Commun 1993;193:631-8.
21. Lopez P, Sippy B, Lambert H, Thach A, Hinton D. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration related choroidal neovascular membranes. Invest Ophthalmol Vis Sci 1996;37:855-68.
22. Bird AC. Bruch's membrane change with age. Br J Ophthalmol 1992;76:166-8.
23. Pauleikhoff D, Barondes MJ, Minassian D, Chisholm IH, Bird AC. Drusen as risk factors in age-related macular disease. Am J Ophthalmol 1990;109: 8-13.
24. Green WR, McDonnell PJ, Yeo JH. Pathologic features of senile macular degeneration. Ophthalmology 1985;92:615-27.
25. Sarks SH. Ageing and degeneration in the macular region: a clinico-pathological study. Br J Ophthalmol 1976;60:324-41.
26. Sheraidah G, Steinmetz R, Maguire J, Pauleikhoff D, Marshall J, Bird AC. Correlation between lipids extracted from Bruch's membrane and age. Ophthalmology 1993;100:47-51.
27. van der Schaft TL, de Bruijn WC, Mooy CM, Ketelaars DA, de Jong PTVM. Element analysis of the early stages of age-related macular degeneration. Arch Ophthalmol 1992; 110:389-94.
28. van der Schaft TL, de Bruijn WC, Mooy CM, Oron FG, Mulder PG, de Jong PTVM. Histologic features of the early stages of age-related macular degeneration. A statistical analysis. Ophthalmology 1992;99:278-86.
29. Vinores SA, Kuchle M, Mahlow J, Chiu C, Green WR, Campochiaro PA. Blood-ocular barrier breakdown in eyes with ocular melanoma. A potential role for vascular endothelial growth factor/vascular permeability factor. Am J Pathol 1995;147:1289-97.
30. Brogi E, Winkles JA, Underwood R, Clinton SK, Alberts GF, Libby P. Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages. J Clin Invest 1993;92:2408-18.
31. Gray K, Eitzman B, Raszmann K, Steed T, Geboff A, McLachlan J, et al. Coordinate regulation by diethylstilbestrol of the platelet-derived growth factor-A (PDGF-A) and -B chains and the PDGF receptor alpha-and beta-subunits in the mouse uterus and vagina: potential mediators of estrogen action. Endocrinology 1995; 136:325-40.
32. Minchenko A, Bauer T, Salceda S, Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 1994;71:374-9.
33. Miller JW, Adamis AP, Shima DT, D'Amore PA, Moulton RS, O'Reilly MS, et al. Vascular endothelial growth factor/ vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol 1994;145:574-84.
34. Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992;359:843-5.
35. Sharma HS, Schaper W. The role of growth factors during development of a collateral circulation in the porcine heart. In: Cummins P, ed. Growth factors and the cardiovascular system. Amsterdam: Kluwer Academic Publishers, 1993.
36. Aiello LP, Northrup JM, Keyt BA, Takagi H, Iwamoto MA. Hypoxic regulation of vascular endothelial growth factor in retinal cells. Arch Ophthalmol 1995;113:1538-44.
37. Vingerling JR, Dielemans I, Bots ML, Hofman A, Grobbee DE, de Jong PT. Age-related macular degeneration is associated with atherosclerosis. The Rotterdam study. Am J Epidemiol 1995;142:404-9.
38. Kliffen M, de Jong PTVM, Luider TM. Protein analysis of human maculae in relation to age-related maculopathy. Lab Invest 1995;73:267-72.
39. Ramrattan RS, van der Schaft TL, Mooy CM, de Bruyn CM, Mulder PGH, de Jong PTVM. Morphometric analysis of Bruch's membrane, the choriocapillaris and the choroid in aging. Invest Ophthalmol Vis Sci 1994;35:2857-64.
40. Pe'er J, Shweiki D, Itin A, Hemo I, Gnessin H, Keshet E. Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases.[See comments] Lab Invest 1995;72: 638-45.
41. Glaser BM, Campochiaro PA, Davis JLJ, Sato M. Retinal pigment epithelial cells release an inhibitor of neovascularization. Arch Ophthalmol 1985;103:1870-5.
42. Penfold PL, Killingsworth MC, Sarks SH. Senile macular degeneration: the involvement of immunocompetent cells. Graefes Arch Clin Exp Ophthalmol 1985;223:69-76.
43. Lopez PF, Grossniklaus HE, Lambert HM, Aaberg TM, Capone A Jr, Stemberg P Jr, et al. Pathologic features of surgically excised subretinal neovascular membranes in age-related macular degeneration. Am J Ophthalmol 1991;112:647-56.
44. Killingsworth MC, Sarks JP, Sarks SH. Macrophages related to Bruch's membrane in age-related macular degeneration. Eye 1990;4:613-21.
45. Clauss M, Gerlach M, Gerlach H, Brett J, Wang F, Familletti PC, et al. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990;172:1535-45.
46. Pertovaara L, Kaipainen A, Mustonen T, Orpana A, Ferrara N, Saksela O, et al. Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. J Biol Chem 1994;269: 6271-4.
47. van der Schaft TL, Mooy CM, de Bruijn WC, Bosman FT, de Jong PTVM. Immunohistochemical light and electron microscopy of basal laminar deposit. Graefes Arch Clin Exp Ophthalmol 1994;232:40-6.
48. Kliffen M, Mooy CM, Luider TM, de Jong PTVM. Analysis of carbohydrate structures in basal laminar deposit in aging human maculae. Invest Ophthalmol Vis Sci 1994;35: 2901-5.
49. Kliffen M, Mooy CM, Luider TM, Huijmans JGM, Kerkvliet S, de Jong PTVM. Identification of glycosaminoglycans in age-related macular deposits. Arch Ophthalmol 1996;114:1009-14.
50. Wahl SM, Hunt DA, Wakefield LM, McCartney-Francis N, Wahl LM, Roberts AB, et al. Transforming growth factor type beta induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci USA 1987;84:5788-92.
51. LaVail MM, Unoki K, Yasumura D, Matthes MT, Yancopoulos GD, Steinberg RH. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA 1992;89:11249-53.
52. Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, LaVail MM. Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat. J Neurosci 1992;12:3554-67.
53. Aiello LP, Pierce EA, Foley ED, Takagi H, Chen H, Riddle L, et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci USA 1995;92:10457-61.
54. D'Amato RJ, Adamis AP. Angiogenesis inhibition in age-related macular degeneration. [Guest editorial] Ophthalmology 1995;102:1261-2.