Enhancement of GABAergic activity: Neuropharmacological effects of benzodiazepines and therapeutic use in anesthesiology

Pharmacological Reviews

Volumn 63, Issue 1, 2011, Pages 243-267

  Saari, Teijo I ^a   Uusi Oukari, Mikko ^b   Ahonen, Jouni ^c   Olkkola, Klaus T ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2; ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; DIAZEPAM; FLUMAZENIL; HYPNOTIC AGENT; INHALATION ANESTHETIC AGENT; LORAZEPAM; MIDAZOLAM; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; REMIMAZOLAM; SEDATIVE AGENT; TEMAZEPAM;

ANESTHESIA; ANESTHESIA INDUCTION; ANESTHESIOLOGY; AWARENESS; BIOTRANSFORMATION; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; DRUG CLEARANCE; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG SOLUBILITY; EPILEPTIC STATE; GABAERGIC SYSTEM; HUMAN; INTENSIVE CARE UNIT; MEMORY; NONHUMAN; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; PKA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REVIEW; SEDATION; SLEEP; UNSPECIFIED SIDE EFFECT;

ANESTHETICS, INTRAVENOUS; ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINES; CENTRAL NERVOUS SYSTEM; DRUG INTERACTIONS; GABA-A RECEPTOR AGONISTS; GAMMA-AMINOBUTYRIC ACID; HUMANS; HYPNOTICS AND SEDATIVES; NEURONS; RECEPTORS, GABA-A;

EID: 79952015165     PISSN: 00316997     EISSN: 15210081     Source Type: Journal    
DOI: 10.1124/pr.110.002717     Document Type: Review

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