Effect of diltiazem on midazolam and alfentanil disposition in patients undergoing coronary artery bypass grafting

Anesthesiology

Volumn 85, Issue 6, 1996, Pages 1246-1252

  Ahonen, Jouni ^a   Olkkola, Klaus T ^a   Salmenperä, Markku ^a   Hynynen, Markku ^a   Neuvonen, Pertti J ^b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Anesthetic, intravenous: alfentanil; midazolam; Drugs: calcium channel blockers; diltiazem; Enzyme: cytochrome P450 3A (CYP3A); Pharmacokinetics and pharmacodynamics: alfentanil; midazolam; drug drug interactions; diltiazem; Surgery: coronary artery bypass graft

Indexed keywords

ALFENTANIL; CYTOCHROME P450; DILTIAZEM; MIDAZOLAM; MIDAZOLAM MALEATE; PROPOFOL;

ADULT; ANESTHETIC RECOVERY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; FIRST PASS EFFECT; GAS CHROMATOGRAPHY; HUMAN; MALE; PHARMACODYNAMICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADJUVANTS, ANESTHESIA; ALFENTANIL; ANESTHESIA RECOVERY PERIOD; ANESTHETICS, INTRAVENOUS; AREA UNDER CURVE; CALCIUM CHANNEL BLOCKERS; CORONARY ARTERY BYPASS; DILTIAZEM; DOUBLE-BLIND METHOD; DRUG INTERACTIONS; FEMALE; HUMANS; MALE; MIDAZOLAM; MIDDLE AGED;

EID: 0030444880     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199612000-00004     Document Type: Article

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