α5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate

Journal of Neuroscience

Volumn 26, Issue 14, 2006, Pages 3713-3720

  Cheng, Victor Y ^a   Martin, Loren J ^a   Elliott, Erin M ^a   Kim, John H ^a,b   Mount, Howard T J ^a,b   Taverna, Franco A ^c   Roder, John C ^c   MacDonald, John F ^a   Bhambri, Amit ^a   Collinson, Neil ^d   Wafford, Keith A ^d   Orser, Beverley A ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^e SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

Amnesia; Anesthesia; Etomidate; GABAA receptor; Learning and memory; Tonic inhibition

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ETOMIDATE; KETAMINE; RECEPTOR SUBUNIT; ANESTHETIC AGENT; GABRA5 PROTEIN, MOUSE; HYPNOTIC SEDATIVE AGENT;

AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN REGION; COMPARATIVE STUDY; CONDUCTANCE; CONTROLLED STUDY; DRUG EFFECT; DRUG RESEARCH; EGO DEVELOPMENT; EVOKED RESPONSE; GENERAL ANESTHESIA; HIPPOCAMPUS; HYPNOSIS; IMMOBILIZATION; IN VITRO STUDY; IN VIVO STUDY; LEARNING; LONG TERM POTENTIATION; MEMORY; MOTOR ACTIVITY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RIGHTING REFLEX; ROTAROD TEST; SEDATION; STRAIN DIFFERENCE; SYNAPTIC TRANSMISSION; TASK PERFORMANCE; WHOLE CELL; WILD TYPE; ACTION POTENTIAL; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; METABOLISM; METHODOLOGY; PHYSIOLOGY;

ACTION POTENTIALS; AMNESIA; ANESTHETICS, GENERAL; ANIMALS; CELLS, CULTURED; ETOMIDATE; HYPNOSIS, ANESTHETIC; HYPNOTICS AND SEDATIVES; LONG-TERM POTENTIATION; MEMORY; MICE; PYRAMIDAL CELLS; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 33645564153     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5024-05.2006     Document Type: Article

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