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Volumn 26, Issue 1, 2006, Pages 23-33

Osmol gap as a surrogate marker for serum propylene glycol concentrations in patients receiving lorazepam for sedation

Author keywords

Hyperosmolality; Lactate; Lorazepam; Osmol gap; Propylene glycol; Toxicology

Indexed keywords

AMPRENAVIR; CHLORDIAZEPOXIDE; COTRIMOXAZOLE; DIAZEPAM; DIGOXIN; DIMENHYDRINATE; ESMOLOL; ETOMIDATE; GLYCERYL TRINITRATE; HYDRALAZINE; LACTIC ACID; LORAZEPAM; LOXAPINE; MULTIVITAMIN; PENTOBARBITAL; PHENOBARBITAL; PHENYTOIN; PHYTOMENADIONE; PROPYLENE GLYCOL; SEDATIVE AGENT; SULFADIAZINE SILVER;

EID: 30544455514     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.2006.26.1.23     Document Type: Article
Times cited : (61)

References (51)
  • 1
    • 30544433361 scopus 로고    scopus 로고
    • Title 21, part 582, subpart B, section 582.1666. April 1, Rockville, MD: Food and Drug Administration
    • Anonymous. 1976 Code of federal regulations. Title 21, volume 6, part 582, subpart B, section 582.1666. April 1, 2003. Rockville, MD: Food and Drug Administration.
    • (2003) 1976 Code of Federal Regulations , vol.6
  • 3
    • 0021995479 scopus 로고
    • A method for predicting survival and mortality of ICU patients using objectively derived weights
    • Lemeshow S, Teres D, Pastides H, Avrunin JS, Steingrub JS. A method for predicting survival and mortality of ICU patients using objectively derived weights. Crit Care Med 1985;13(7):519-25.
    • (1985) Crit Care Med , vol.13 , Issue.7 , pp. 519-525
    • Lemeshow, S.1    Teres, D.2    Pastides, H.3    Avrunin, J.S.4    Steingrub, J.S.5
  • 4
    • 0027422556 scopus 로고
    • Mortality probability models (MPM II) based on an international cohort of intensive care unit patients
    • Lemeshow S, Teres D, Klar J, Avrunin JS, Gehlbach SH, Rapoport J. Mortality probability models (MPM II) based on an international cohort of intensive care unit patients. JAMA 1993;270(20):2478-86.
    • (1993) JAMA , vol.270 , Issue.20 , pp. 2478-2486
    • Lemeshow, S.1    Teres, D.2    Klar, J.3    Avrunin, J.S.4    Gehlbach, S.H.5    Rapoport, J.6
  • 5
    • 0028018017 scopus 로고
    • Mortality probability models for patients in the intensive care unit for 48 or 72 hours: A prospective, multicenter study
    • Lemeshow S, Klar J, Teres D, et al. Mortality probability models for patients in the intensive care unit for 48 or 72 hours: a prospective, multicenter study. Crit Care Med 1994;22(9):1351-8.
    • (1994) Crit Care Med , vol.22 , Issue.9 , pp. 1351-1358
    • Lemeshow, S.1    Klar, J.2    Teres, D.3
  • 6
    • 0029142658 scopus 로고
    • A comparison of severity of illness scoring systems for intensive care unit patients: Results of a multicenter, multinational study: The European/North American severity study group
    • Castella X, Artigas A, Bipn J, Kari A. A comparison of severity of illness scoring systems for intensive care unit patients: results of a multicenter, multinational study: the European/North American severity study group. Crit Care Med 1995;23(8):1327-35.
    • (1995) Crit Care Med , vol.23 , Issue.8 , pp. 1327-1335
    • Castella, X.1    Artigas, A.2    Bipn, J.3    Kari, A.4
  • 7
    • 0033838944 scopus 로고    scopus 로고
    • Performance of the mortality probability models in assessing severity of illness during the first week in the intensive care unit
    • Rue M, Artigas A, Alvarez M, Quintana S, Valero C. Performance of the mortality probability models in assessing severity of illness during the first week in the intensive care unit. Crit Care Med 2000;28(8):2819-24.
    • (2000) Crit Care Med , vol.28 , Issue.8 , pp. 2819-2824
    • Rue, M.1    Artigas, A.2    Alvarez, M.3    Quintana, S.4    Valero, C.5
  • 8
    • 0016585051 scopus 로고
    • Comparison of methods for calculating serum osmolality from chemical concentrations, and the prognostic value of such calculations
    • Dorwart WV, Chalmers L. Comparison of methods for calculating serum osmolality from chemical concentrations, and the prognostic value of such calculations. Clin Chem 1975;21(2):190-4.
    • (1975) Clin Chem , vol.21 , Issue.2 , pp. 190-194
    • Dorwart, W.V.1    Chalmers, L.2
  • 9
    • 0141791620 scopus 로고    scopus 로고
    • Osmolality and osmolarity: Narrowing the terminology gap
    • Erstad BL. Osmolality and osmolarity: narrowing the terminology gap. Pharmacotherapy 2003;23(9):1085-6.
    • (2003) Pharmacotherapy , vol.23 , Issue.9 , pp. 1085-1086
    • Erstad, B.L.1
  • 11
    • 0036265681 scopus 로고    scopus 로고
    • Propylene glycol toxicity associated with lorazepam infusion in a patient receiving continuous veno-venous hemofiltration with dialysis
    • Al Khafaji AH, Dewhirst WE, Manning HL. Propylene glycol toxicity associated with lorazepam infusion in a patient receiving continuous veno-venous hemofiltration with dialysis. Anesth Analg 2002;94(6):1583-5.
    • (2002) Anesth Analg , vol.94 , Issue.6 , pp. 1583-1585
    • Al Khafaji, A.H.1    Dewhirst, W.E.2    Manning, H.L.3
  • 12
    • 0033895507 scopus 로고    scopus 로고
    • Osmolar gap metabolic acidosis in a 60-year-old man treated for hypoxemic respiratory failure
    • Arbour R, Esparis B. Osmolar gap metabolic acidosis in a 60-year-old man treated for hypoxemic respiratory failure. Chest 2000;118(2):545-6.
    • (2000) Chest , vol.118 , Issue.2 , pp. 545-546
    • Arbour, R.1    Esparis, B.2
  • 13
    • 0032605184 scopus 로고    scopus 로고
    • Propylene glycol toxicity related to high-dose lorazepam infusion: Case report and discussion
    • Arbour RB. Propylene glycol toxicity related to high-dose lorazepam infusion: case report and discussion. Am J Crit Care 1999;8(1):499-506.
    • (1999) Am J Crit Care , vol.8 , Issue.1 , pp. 499-506
    • Arbour, R.B.1
  • 14
    • 0034861426 scopus 로고    scopus 로고
    • Short-term lorazepam infusion and concern for propylene glycol toxicity: Case report and review
    • Cawley MJ. Short-term lorazepam infusion and concern for propylene glycol toxicity: case report and review. Pharmacotherapy 2001;21(9):1140-4.
    • (2001) Pharmacotherapy , vol.21 , Issue.9 , pp. 1140-1144
    • Cawley, M.J.1
  • 15
    • 0036885169 scopus 로고    scopus 로고
    • Propylene glycol accumulation associated with continuous infusion of lorazepam in pediatric intensive care patients
    • Chicella M, Jansen P, Parthiban A, et al. Propylene glycol accumulation associated with continuous infusion of lorazepam in pediatric intensive care patients. Crit Care Med 2002;30(12):2752-6.
    • (2002) Crit Care Med , vol.30 , Issue.12 , pp. 2752-2756
    • Chicella, M.1    Jansen, P.2    Parthiban, A.3
  • 16
    • 0001356582 scopus 로고
    • Propylene glycol-induced lactic acidosis secondary to a continuous infusion of lorazepam
    • D'Ambrosio J, Borchart-Phelps P, Nolen J, Cerra F. Propylene glycol-induced lactic acidosis secondary to a continuous infusion of lorazepam [abstr]. Pharmacotherapy 1993;13(3):274.
    • (1993) Pharmacotherapy , vol.13 , Issue.3 , pp. 274
    • D'Ambrosio, J.1    Borchart-Phelps, P.2    Nolen, J.3    Cerra, F.4
  • 17
    • 18044389814 scopus 로고    scopus 로고
    • Monitoring lorazepam induced propylene glycol toxicity in a critical care population: A prospective case series
    • Hayman M, Seidl E, Anderson J, Harchelroad F. Monitoring lorazepam induced propylene glycol toxicity in a critical care population: a prospective case series [abstr]. Crit Care Med 2001;30(12):A157.
    • (2001) Crit Care Med , vol.30 , Issue.12
    • Hayman, M.1    Seidl, E.2    Anderson, J.3    Harchelroad, F.4
  • 18
    • 0141857175 scopus 로고    scopus 로고
    • Acute tubular necrosis associated with propylene glycol from concomitant administration of intravenous lorazepam and trimethoprimsulfamethoxazole
    • Hayman M, Seidl E, Ali M, Malik K. Acute tubular necrosis associated with propylene glycol from concomitant administration of intravenous lorazepam and trimethoprimsulfamethoxazole. Pharmacotherapy 2003;23(9):1190-4.
    • (2003) Pharmacotherapy , vol.23 , Issue.9 , pp. 1190-1194
    • Hayman, M.1    Seidl, E.2    Ali, M.3    Malik, K.4
  • 19
    • 30544433133 scopus 로고    scopus 로고
    • Significant osmolar gap and anion gap metabolic acidosis from high-dose lorazepam infusion in a critically ill adolescent
    • Kallas P. Significant osmolar gap and anion gap metabolic acidosis from high-dose lorazepam infusion in a critically ill adolescent. J Toxicol 2000;38:538-9.
    • (2000) J Toxicol , vol.38 , pp. 538-539
    • Kallas, P.1
  • 20
    • 0028879080 scopus 로고
    • Polyethylene glycol nephrotoxicity secondary to prolonged high-dose intravenous lorazepam
    • Laine GA, Hossain SM, Solls RT, Adams SC. Polyethylene glycol nephrotoxicity secondary to prolonged high-dose intravenous lorazepam. Ann Pharmacother 1995;29(11):1110-14.
    • (1995) Ann Pharmacother , vol.29 , Issue.11 , pp. 1110-1114
    • Laine, G.A.1    Hossain, S.M.2    Solls, R.T.3    Adams, S.C.4
  • 21
    • 0036163664 scopus 로고    scopus 로고
    • Removal of propylene glycol and correction of increased osmolar gap by hemodialysis in a patient on high dose lorazepam infusion therapy
    • Parker MG, Fraser GL, Watson DM, Riker RR. Removal of propylene glycol and correction of increased osmolar gap by hemodialysis in a patient on high dose lorazepam infusion therapy. Intensive Care Med 2002;28(1):81-4.
    • (2002) Intensive Care Med , vol.28 , Issue.1 , pp. 81-84
    • Parker, M.G.1    Fraser, G.L.2    Watson, D.M.3    Riker, R.R.4
  • 22
    • 0034039761 scopus 로고    scopus 로고
    • Hyperlactatemia, increased osmolar gap, and renal dysfunction during continuous lorazepam infusion
    • Reynolds HN, Teiken P, Regan ME, et al. Hyperlactatemia, increased osmolar gap, and renal dysfunction during continuous lorazepam infusion. Crit Care Med 2000;28(5):1631-4.
    • (2000) Crit Care Med , vol.28 , Issue.5 , pp. 1631-1634
    • Reynolds, H.N.1    Teiken, P.2    Regan, M.E.3
  • 23
    • 0030947364 scopus 로고    scopus 로고
    • Comment: Possible toxicity from propylene glycol in lorazepam infusion
    • Seay RE, Graves PJ, Wilkin MK. Comment: possible toxicity from propylene glycol in lorazepam infusion. Ann Pharmacother 1997;31(5):647-8.
    • (1997) Ann Pharmacother , vol.31 , Issue.5 , pp. 647-648
    • Seay, R.E.1    Graves, P.J.2    Wilkin, M.K.3
  • 24
    • 0037129444 scopus 로고    scopus 로고
    • Severe hyperosmolar metabolic acidosis due to a large dose of intravenous lorazepam
    • Tayar J, Jabbour G, Saggi SJ. Severe hyperosmolar metabolic acidosis due to a large dose of intravenous lorazepam. N Engl J Med 2002;346(16):1253-4.
    • (2002) N Engl J Med , vol.346 , Issue.16 , pp. 1253-1254
    • Tayar, J.1    Jabbour, G.2    Saggi, S.J.3
  • 26
    • 0141456730 scopus 로고    scopus 로고
    • Propylene glycol-associated renal toxicity from lorazepam infusion
    • Taucher N, Fish J, Smith H, Wells J. Propylene glycol-associated renal toxicity from lorazepam infusion. Pharmacotherapy 2003;23(9):1094-9.
    • (2003) Pharmacotherapy , vol.23 , Issue.9 , pp. 1094-1099
    • Taucher, N.1    Fish, J.2    Smith, H.3    Wells, J.4
  • 27
    • 3943098025 scopus 로고    scopus 로고
    • Relationship of continuous infusion lorazepam to serum propylene glycol concentration in critically ill adults
    • Arroliga AC, Shehab N, McCarthy K, Gonzales JP. Relationship of continuous infusion lorazepam to serum propylene glycol concentration in critically ill adults. Crit Care Med 2004;32:1709-14.
    • (2004) Crit Care Med , vol.32 , pp. 1709-1714
    • Arroliga, A.C.1    Shehab, N.2    McCarthy, K.3    Gonzales, J.P.4
  • 28
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16(1):31-41.
    • (1976) Nephron , vol.16 , Issue.1 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 29
    • 0021828788 scopus 로고
    • Pharmacokinetics of propylene glycol in humans during multiple dosing regimens
    • Yu DK, Elmquist WF, Sawchuk RJ. Pharmacokinetics of propylene glycol in humans during multiple dosing regimens. J Pharm Sci 1985;74(8):876-9.
    • (1985) J Pharm Sci , vol.74 , Issue.8 , pp. 876-879
    • Yu, D.K.1    Elmquist, W.F.2    Sawchuk, R.J.3
  • 30
    • 0023191970 scopus 로고
    • Propylene glycol pharmacokinetics and effects after intravenous infusion in humans
    • Speth PA, Vree TB, Neilen NF, et al. Propylene glycol pharmacokinetics and effects after intravenous infusion in humans. Ther Drug Monit 1987;9(3):255-8.
    • (1987) Ther Drug Monit , vol.9 , Issue.3 , pp. 255-258
    • Speth, P.A.1    Vree, T.B.2    Neilen, N.F.3
  • 31
    • 0015265455 scopus 로고
    • Toxicology, metabolism, and biochemistry of 1,2-propanediol
    • Ruddick JA. Toxicology, metabolism, and biochemistry of 1,2-propanediol. Toxicol Appl Pharmacol 1972;21(1):102-11.
    • (1972) Toxicol Appl Pharmacol , vol.21 , Issue.1 , pp. 102-111
    • Ruddick, J.A.1
  • 33
    • 0018841136 scopus 로고
    • Hyperosmolality in the burn patient: Analysis of an osmolal discrepancy
    • Kulick MI, Lewis NS, Bansal V, Warpeha R. Hyperosmolality in the burn patient: analysis of an osmolal discrepancy. J Trauma 1980;20(3):223-8.
    • (1980) J Trauma , vol.20 , Issue.3 , pp. 223-228
    • Kulick, M.I.1    Lewis, N.S.2    Bansal, V.3    Warpeha, R.4
  • 34
    • 0021989981 scopus 로고
    • Hyperosmolality induced by propylene glycol: A complication of silver sulfadiazine therapy
    • Fligner CL, Jack R, Twiggs GA, Raisys VA. Hyperosmolality induced by propylene glycol: a complication of silver sulfadiazine therapy. JAMA 1985;253(11):1606-9.
    • (1985) JAMA , vol.253 , Issue.11 , pp. 1606-1609
    • Fligner, C.L.1    Jack, R.2    Twiggs, G.A.3    Raisys, V.A.4
  • 35
    • 0031734769 scopus 로고    scopus 로고
    • Coma in a premature infant associated with the transdermal absorption of propylene glycol
    • Peleg O, Bar-Oz B, Arad I. Coma in a premature infant associated with the transdermal absorption of propylene glycol. Acta Paediatr 1998;87(11):1195-6.
    • (1998) Acta Paediatr , vol.87 , Issue.11 , pp. 1195-1196
    • Peleg, O.1    Bar-Oz, B.2    Arad, I.3
  • 37
    • 0029132678 scopus 로고
    • Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema
    • Levy ML, Aranda M, Zelman V, Giannotta SL. Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema. Neurosurgery 1995;37(2):363-9.
    • (1995) Neurosurgery , vol.37 , Issue.2 , pp. 363-369
    • Levy, M.L.1    Aranda, M.2    Zelman, V.3    Giannotta, S.L.4
  • 40
    • 0023951963 scopus 로고
    • Propylene glycol-induced side effects during intravenous nitroglycerin therapy
    • Demey HE, Daelemans RA, Verpooten GA, et al. Propylene glycol-induced side effects during intravenous nitroglycerin therapy. Intensive Care Med 1988;14(3):221-6.
    • (1988) Intensive Care Med , vol.14 , Issue.3 , pp. 221-226
    • Demey, H.E.1    Daelemans, R.A.2    Verpooten, G.A.3
  • 41
    • 0031712201 scopus 로고    scopus 로고
    • Pediatric use of intravenous and intramuscular phenytoin: Lessons learned
    • Wheless JW. Pediatric use of intravenous and intramuscular phenytoin: lessons learned. J Child Neurol 1998;13(suppl 1):S11-14.
    • (1998) J Child Neurol , vol.13 , Issue.SUPPL. 1
    • Wheless, J.W.1
  • 42
    • 0029825880 scopus 로고    scopus 로고
    • Propylene glycol: The safe diluent that continues to cause harm
    • Glover ML, Reed MD. Propylene glycol: the safe diluent that continues to cause harm. Pharmacotherapy 1996;16(4):690-3.
    • (1996) Pharmacotherapy , vol.16 , Issue.4 , pp. 690-693
    • Glover, M.L.1    Reed, M.D.2
  • 43
    • 0028067884 scopus 로고
    • Propylene glycol dermatitis: Reevaluation of an old problem
    • Funk JO, Maibach HI. Propylene glycol dermatitis: reevaluation of an old problem. Contact Dermatitis 1994;31(4):236-41.
    • (1994) Contact Dermatitis , vol.31 , Issue.4 , pp. 236-241
    • Funk, J.O.1    Maibach, H.I.2
  • 44
    • 0029027327 scopus 로고
    • Systemic contact dermatitis due to intravenous Valium in a person sensitive to propylene glycol
    • Fisher AA. Systemic contact dermatitis due to intravenous Valium in a person sensitive to propylene glycol. Cutis 1995;55(6):327-8.
    • (1995) Cutis , vol.55 , Issue.6 , pp. 327-328
    • Fisher, A.A.1
  • 46
    • 0017892941 scopus 로고
    • Central nervous system toxicity associated with ingestion of propylene glycol
    • Arulanantham K, Genel M. Central nervous system toxicity associated with ingestion of propylene glycol. J Pediatr 1978;93(3):515-16.
    • (1978) J Pediatr , vol.93 , Issue.3 , pp. 515-516
    • Arulanantham, K.1    Genel, M.2
  • 47
    • 0023734960 scopus 로고
    • Cerebral depression due to propylene glycol in a patient with chronic epilepsy: The value of the plasma osmolal gap in diagnosis
    • Lolin Y, Francis DA, Flanagan RJ, Little P, Lascelles PT. Cerebral depression due to propylene glycol in a patient with chronic epilepsy: the value of the plasma osmolal gap in diagnosis. Postgrad Med J 1988;64(754):610-13.
    • (1988) Postgrad Med J , vol.64 , Issue.754 , pp. 610-613
    • Lolin, Y.1    Francis, D.A.2    Flanagan, R.J.3    Little, P.4    Lascelles, P.T.5
  • 48
    • 0022301449 scopus 로고
    • Propylene glycol-induced heparin resistance during nitroglycerin infusion
    • Col J, Col-Debeys C, Lavenne-Pardonge E, et al. Propylene glycol-induced heparin resistance during nitroglycerin infusion. Am Heart J 1985;110(1 pt 1):171-3.
    • (1985) Am Heart J , vol.110 , Issue.1 PART 1 , pp. 171-173
    • Col, J.1    Col-Debeys, C.2    Lavenne-Pardonge, E.3
  • 49
    • 0023248353 scopus 로고
    • Heparin resistance induced by intravenous nitroglycerin: A word of caution when both drugs are used concomitantly
    • Habbab MA, Haft JI. Heparin resistance induced by intravenous nitroglycerin: a word of caution when both drugs are used concomitantly. Arch Intern Med 1987;147(5):857-60.
    • (1987) Arch Intern Med , vol.147 , Issue.5 , pp. 857-860
    • Habbab, M.A.1    Haft, J.I.2
  • 50
    • 0034648744 scopus 로고    scopus 로고
    • Propylene glycol toxicity in a patient receiving intravenous diazepam
    • Wilson KC, Reardon C, Farber HW. Propylene glycol toxicity in a patient receiving intravenous diazepam [letter]. N Engl J Med 2000;343(11):815.
    • (2000) N Engl J Med , vol.343 , Issue.11 , pp. 815
    • Wilson, K.C.1    Reardon, C.2    Farber, H.W.3
  • 51
    • 0025837105 scopus 로고
    • A case of propylene glycol toxic reaction associated with etomidate infusion
    • Bedichek E, Kirschbaum B. A case of propylene glycol toxic reaction associated with etomidate infusion. Arch Intern Med 1991;151(11):2297-8.
    • (1991) Arch Intern Med , vol.151 , Issue.11 , pp. 2297-2298
    • Bedichek, E.1    Kirschbaum, B.2


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