메뉴 건너뛰기




Volumn 165, Issue 12, 2008, Pages 1594-1603

Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia patients

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA6; 4 AMINOBUTYRIC ACID A RECEPTOR BETA3; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; 4 AMINOBUTYRIC ACID CARRIER; CHLORPROMAZINE; CLOZAPINE; DRUG VEHICLE; FLUPHENAZINE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; GLUTAMATE RECEPTOR 6; HALOPERIDOL; KAINIC ACID RECEPTOR; KAINIC ACID RECEPTOR SUBUNIT 2; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2C; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2D; NEURONAL NITRIC OXIDE SYNTHASE; OLANZAPINE; PARVALBUMIN; PERPHENAZINE; RECEPTOR SUBUNIT; RISPERIDONE; THIORIDAZINE; UNCLASSIFIED DRUG;

EID: 56649099232     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2008.07121845     Document Type: Article
Times cited : (87)

References (40)
  • 2
    • 33747872904 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders
    • Akbarian S, Huang HS: Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res Rev 2006; 52:293-304
    • (2006) Brain Res Rev , vol.52 , pp. 293-304
    • Akbarian, S.1    Huang, H.S.2
  • 3
  • 4
    • 0035007327 scopus 로고    scopus 로고
    • GABAergic interneurons: Implications for understanding schizophrenia and bipolar disorder
    • Benes FM, Berretta S: GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 2001; 25:1-27
    • (2001) Neuropsychopharmacology , vol.25 , pp. 1-27
    • Benes, F.M.1    Berretta, S.2
  • 5
    • 0034011252 scopus 로고    scopus 로고
    • Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia
    • Volk DW, Austin MC, Pierri JN, Sampson AR, Lewis DA: Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. Arch Gen Psychiatry 2000; 57:237-245
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 237-245
    • Volk, D.W.1    Austin, M.C.2    Pierri, J.N.3    Sampson, A.R.4    Lewis, D.A.5
  • 8
    • 0036269901 scopus 로고    scopus 로고
    • Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia
    • Heckers S, Stone D, Walsh J, Shick J, Koul P, Benes FM: Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia. Arch Gen Psychiatry 2002; 59:521-529
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 521-529
    • Heckers, S.1    Stone, D.2    Walsh, J.3    Shick, J.4    Koul, P.5    Benes, F.M.6
  • 9
    • 3042782805 scopus 로고    scopus 로고
    • Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder
    • Woo TU, Walsh JP, Benes FM: Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch Gen Psychiatry 2004; 61:649-657
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 649-657
    • Woo, T.U.1    Walsh, J.P.2    Benes, F.M.3
  • 11
    • 9244249796 scopus 로고    scopus 로고
    • GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and reelin proteins in cerebellum
    • Fatemi SH, Stary JM, Earle JA, Araghi-Niknam M, Eagan E: GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and reelin proteins in cerebellum. Schizophr Res 2005; 72:109-122
    • (2005) Schizophr Res , vol.72 , pp. 109-122
    • Fatemi, S.H.1    Stary, J.M.2    Earle, J.A.3    Araghi-Niknam, M.4    Eagan, E.5
  • 12
    • 0035140656 scopus 로고    scopus 로고
    • GABA transporter-1 mRNA in the prefrontal cortex in schizophrenia: Decreased expression in a subset of neurons
    • Volk D, Austin M, Pierri J, Sampson A, Lewis D: GABA transporter-1 mRNA in the prefrontal cortex in schizophrenia: decreased expression in a subset of neurons. Am J Psychiatry 2001; 158:256-265
    • (2001) Am J Psychiatry , vol.158 , pp. 256-265
    • Volk, D.1    Austin, M.2    Pierri, J.3    Sampson, A.4    Lewis, D.5
  • 13
    • 0026612361 scopus 로고
    • Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics
    • Benes FM, Vincent SL, Alsterberg G, Bird ED, SanGiovanni JP: Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics. J Neurosci 1992; 12:924-929
    • (1992) J Neurosci , vol.12 , pp. 924-929
    • Benes, F.M.1    Vincent, S.L.2    Alsterberg, G.3    Bird, E.D.4    SanGiovanni, J.P.5
  • 14
    • 0030331175 scopus 로고    scopus 로고
    • A receptor binding on neurons of the prefrontal cortex in schizophrenic subjects
    • A receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience 1996; 75:1021-1031
    • (1996) Neuroscience , vol.75 , pp. 1021-1031
    • Benes, F.M.1    Vincent, S.L.2    Marie, A.3    Khan, Y.4
  • 15
    • 0036784474 scopus 로고    scopus 로고
    • Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia
    • Volk DW, Pierri JN, Fritschy JM, Auh S, Sampson AR, Lewis DA: Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia. Cereb Cortex 2002; 12:1063-1070
    • (2002) Cereb Cortex , vol.12 , pp. 1063-1070
    • Volk, D.W.1    Pierri, J.N.2    Fritschy, J.M.3    Auh, S.4    Sampson, A.R.5    Lewis, D.A.6
  • 18
    • 0031976207 scopus 로고    scopus 로고
    • The cerebellar cognitive affective syndrome
    • Schmahmann JD, Sherman JC: The cerebellar cognitive affective syndrome. Brain 1998; 121(pt 4):561-579
    • (1998) Brain , vol.121 , Issue.PART 4 , pp. 561-579
    • Schmahmann, J.D.1    Sherman, J.C.2
  • 19
    • 33745635032 scopus 로고    scopus 로고
    • The primate cortico-cerebellar system: Anatomy and function
    • Ramnani N: The primate cortico-cerebellar system: anatomy and function. Nat Rev Neurosci 2006; 7:511-522
    • (2006) Nat Rev Neurosci , vol.7 , pp. 511-522
    • Ramnani, N.1
  • 23
    • 0037221973 scopus 로고    scopus 로고
    • The axonal chemorepellant Semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology
    • Eastwood SL, Law AJ, Everall IP, Harrison PJ: The axonal chemorepellant Semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology. Mol Psychiatry 2003; 8:148-155
    • (2003) Mol Psychiatry , vol.8 , pp. 148-155
    • Eastwood, S.L.1    Law, A.J.2    Everall, I.P.3    Harrison, P.J.4
  • 26
    • 2342451962 scopus 로고    scopus 로고
    • Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus
    • Bai O, Zhang H, Li XM: Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus. Brain Res 2004; 1010:81-86
    • (2004) Brain Res , vol.1010 , pp. 81-86
    • Bai, O.1    Zhang, H.2    Li, X.M.3
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) method
    • Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) method. Methods 2001; 25:402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 30
    • 0029965427 scopus 로고    scopus 로고
    • Glutamate receptors mediate dynamic regulation of nitric oxide synthase expression in cerebellar granule cells
    • Baader SL, Schilling K: Glutamate receptors mediate dynamic regulation of nitric oxide synthase expression in cerebellar granule cells. J Neurosci 1996; 16:1440-1449
    • (1996) J Neurosci , vol.16 , pp. 1440-1449
    • Baader, S.L.1    Schilling, K.2
  • 32
    • 0042318593 scopus 로고    scopus 로고
    • Endogenous nitric oxide modulates GABAergic transmission to granule cells in adult rat cerebellum
    • Wall MJ: Endogenous nitric oxide modulates GABAergic transmission to granule cells in adult rat cerebellum. Eur J Neurosci 2003; 18:869-878
    • (2003) Eur J Neurosci , vol.18 , pp. 869-878
    • Wall, M.J.1
  • 33
    • 0030933984 scopus 로고    scopus 로고
    • Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia
    • Porter RH, Eastwood SL, Harrison PJ: Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Res 1997; 751:217-231
    • (1997) Brain Res , vol.751 , pp. 217-231
    • Porter, R.H.1    Eastwood, S.L.2    Harrison, P.J.3
  • 35
    • 33744945506 scopus 로고    scopus 로고
    • Cerebellar circuitry as a neuronal machine
    • Ito M: Cerebellar circuitry as a neuronal machine. Prog Neurobiol 2006; 78:272-303
    • (2006) Prog Neurobiol , vol.78 , pp. 272-303
    • Ito, M.1
  • 36
    • 23644432374 scopus 로고    scopus 로고
    • Developmental expression of GABA transporter-1 and 3 during formation of the GABAergic synapses in the mouse cerebellar cortex
    • Takayama C, Inoue Y: Developmental expression of GABA transporter-1 and 3 during formation of the GABAergic synapses in the mouse cerebellar cortex. Brain Res Dev Brain Res 2005; 158:41-49
    • (2005) Brain Res Dev Brain Res , vol.158 , pp. 41-49
    • Takayama, C.1    Inoue, Y.2
  • 37
    • 1442349271 scopus 로고    scopus 로고
    • Distribution of calcium-binding proteins in the cerebellum
    • Bastianelli E: Distribution of calcium-binding proteins in the cerebellum. Cerebellum 2003; 2:242-262
    • (2003) Cerebellum , vol.2 , pp. 242-262
    • Bastianelli, E.1
  • 38
    • 35548991088 scopus 로고    scopus 로고
    • NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons
    • Homayoun H, Moghaddam B: NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J Neurosci 2007; 27:11496-11500
    • (2007) J Neurosci , vol.27 , pp. 11496-11500
    • Homayoun, H.1    Moghaddam, B.2
  • 39
  • 40
    • 2942534284 scopus 로고    scopus 로고
    • Cerebellar dysfunction in neuroleptic naive schizophrenia patients: Clinical, cognitive, and neuroanatomic correlates of cerebellar neurologic signs
    • Ho BC, Mola C, Andreasen NC: Cerebellar dysfunction in neuroleptic naive schizophrenia patients: clinical, cognitive, and neuroanatomic correlates of cerebellar neurologic signs. Biol Psychiatry 2004; 55:1146-1153
    • (2004) Biol Psychiatry , vol.55 , pp. 1146-1153
    • Ho, B.C.1    Mola, C.2    Andreasen, N.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.