-
1
-
-
16444387677
-
GABAA receptor structure-function studies: A reexamination in light of new acetylcholine receptor structures
-
Akabas MH (2004) GABAA receptor structure-function studies: a reexamination in light of new acetylcholine receptor structures. Int Rev Neurobiol 62:1-43.
-
(2004)
Int Rev Neurobiol
, vol.62
, pp. 1-43
-
-
Akabas, M.H.1
-
3
-
-
0038178877
-
The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia
-
Belelli D, Muntoni AL, Merrywest SD, Gentet LJ, Casula A, Callachan H, Madau P, Gemmell DK, Hamilton NM, Lambert JJ, et al. (2003) The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia. Neuropharmacology 45:57-71.
-
(2003)
Neuropharmacology
, vol.45
, pp. 57-71
-
-
Belelli, D.1
Muntoni, A.L.2
Merrywest, S.D.3
Gentet, L.J.4
Casula, A.5
Callachan, H.6
Madau, P.7
Gemmell, D.K.8
Hamilton, N.M.9
Lambert, J.J.10
-
4
-
-
0035237928
-
Molecular modeling of ligand-gated ion channels: Progress and challenges
-
Bertaccini E and Trudell JR (2001) Molecular modeling of ligand-gated ion channels: progress and challenges. Int Rev Neurobiol 48:141-166.
-
(2001)
Int Rev Neurobiol
, vol.48
, pp. 141-166
-
-
Bertaccini, E.1
Trudell, J.R.2
-
5
-
-
0033492836
-
Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: Three residues are required for allosteric coupling
-
Boileau AJ and Czajkowski C (1999) Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: three residues are required for allosteric coupling. J Neurosci 19:10213-10220.
-
(1999)
J Neurosci
, vol.19
, pp. 10213-10220
-
-
Boileau, A.J.1
Czajkowski, C.2
-
6
-
-
4344616080
-
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel
-
Bouzat C, Gumilar F, Spitzmaul G, Wang HL, Rayes D, Hansen SB, Taylor P, and Sine SM (2004) Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature (Lond) 430:896-900.
-
(2004)
Nature (Lond)
, vol.430
, pp. 896-900
-
-
Bouzat, C.1
Gumilar, F.2
Spitzmaul, G.3
Wang, H.L.4
Rayes, D.5
Hansen, S.B.6
Taylor, P.7
Sine, S.M.8
-
7
-
-
0342424187
-
Fast prediction and visualization of protein binding pockets with PASS
-
Brady GP and Stouten PFW (2000) Fast prediction and visualization of protein binding pockets with PASS. J Comput-Aided Mol Des 14:383-401.
-
(2000)
J Comput-Aided Mol Des
, vol.14
, pp. 383-401
-
-
Brady, G.P.1
Stouten, P.F.W.2
-
8
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, and Sixma TK (2001) Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature (Lond) 411:269-276.
-
(2001)
Nature (Lond)
, vol.411
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van Der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
10
-
-
0038771238
-
Comparative modeling of GABA(A) receptors: Limits, insights, future developments
-
Ernst M, Brauchart D, Boresch S, and Sieghart W (2003) Comparative modeling of GABA(A) receptors: limits, insights, future developments. Neuroscience 119:933-943.
-
(2003)
Neuroscience
, vol.119
, pp. 933-943
-
-
Ernst, M.1
Brauchart, D.2
Boresch, S.3
Sieghart, W.4
-
12
-
-
0001962564
-
The molecular modeling toolkit: A new approach to molecular simulations
-
Hinsen K (2000) The molecular modeling toolkit: a new approach to molecular simulations. J Comp Chem 21:79-85.
-
(2000)
J Comp Chem
, vol.21
, pp. 79-85
-
-
Hinsen, K.1
-
13
-
-
0035869928
-
Evidence for a common binding cavity for three general anesthetics within the GABAA receptor
-
Jenkins A, Greenblatt EP, Faulkner HJ, Bertaccini E, Light A, Lin A, Andreasen A, Viner A, Trudell JR, and Harrison NL (2001) Evidence for a common binding cavity for three general anesthetics within the GABAA receptor. J Neurosci 21:RC136.
-
(2001)
J Neurosci
, vol.21
-
-
Jenkins, A.1
Greenblatt, E.P.2
Faulkner, H.J.3
Bertaccini, E.4
Light, A.5
Lin, A.6
Andreasen, A.7
Viner, A.8
Trudell, J.R.9
Harrison, N.L.10
-
16
-
-
0037448581
-
Coupling of agonist binding to channel gating in the GABA(A) receptor
-
Kash TL, Jenkins A, Kelley JC, Trudell JR, and Harrison NL (2003) Coupling of agonist binding to channel gating in the GABA(A) receptor. Nature (Lond) 421:272-275.
-
(2003)
Nature (Lond)
, vol.421
, pp. 272-275
-
-
Kash, T.L.1
Jenkins, A.2
Kelley, J.C.3
Trudell, J.R.4
Harrison, N.L.5
-
17
-
-
7444260900
-
Evaluation of a proposed mechanism of ligand-gated ion channel activation in the GABAA and glycine receptors
-
Kash TL, Kim T, Trudell JR, and Harrison NL (2004b) Evaluation of a proposed mechanism of ligand-gated ion channel activation in the GABAA and glycine receptors. Neurosci Lett 371:230-234.
-
(2004)
Neurosci Lett
, vol.371
, pp. 230-234
-
-
Kash, T.L.1
Kim, T.2
Trudell, J.R.3
Harrison, N.L.4
-
18
-
-
3042515233
-
Structural elements involved in activation of the gamma-aminobutyric acid type A (GABAA) receptor
-
Kash TL, Trudell JR, and Harrison NL (2004c) Structural elements involved in activation of the gamma-aminobutyric acid type A (GABAA) receptor. Biochem Soc Trans 32:540-546.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 540-546
-
-
Kash, T.L.1
Trudell, J.R.2
Harrison, N.L.3
-
19
-
-
0000243829
-
PROCHECK: A program to check the sterochemical quality of protein structures
-
Laskowski RA, MacArthur MW, Moss DS, and Thornton JM (1993) PROCHECK: a program to check the sterochemical quality of protein structures. J Appl Cryst 26:283-291.
-
(1993)
J Appl Cryst
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
20
-
-
4143058002
-
Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening
-
Lobo IA, Trudell JR, and Harris RA (2004) Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. J Neurochem 90:962-969.
-
(2004)
J Neurochem
, vol.90
, pp. 962-969
-
-
Lobo, I.A.1
Trudell, J.R.2
Harris, R.A.3
-
21
-
-
0033873929
-
Comparative protein structure modeling of genes and genomes
-
Marti-Renom MA, Stuart AC, Fiser A, Sanchez R, Melo F, and Sali A (2000) Comparative protein structure modeling of genes and genomes. Annu Rev Biophys Biomol Struct 29:291-325.
-
(2000)
Annu Rev Biophys Biomol Struct
, vol.29
, pp. 291-325
-
-
Marti-Renom, M.A.1
Stuart, A.C.2
Fiser, A.3
Sanchez, R.4
Melo, F.5
Sali, A.6
-
22
-
-
0034255021
-
Specific binding sites for alcohols and anesthetics on ligand-gated ion channels
-
Mascia MP, Trudell JR, and Harris RA (2000) Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proc Natl Acad Sci USA 97:9305-9310.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9305-9310
-
-
Mascia, M.P.1
Trudell, J.R.2
Harris, R.A.3
-
23
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A, Fujiyoshi Y, and Unwin N (2003) Structure and gating mechanism of the acetylcholine receptor pore. Nature (Lond) 423:949-955.
-
(2003)
Nature (Lond)
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
24
-
-
13444272079
-
The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis
-
Pearl F, Todd A, Sillitoe I, Dibley M, Redfern O, Lewis T, Bennett C, Marsden R, Grant A, Lee D, et al. (2005) The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis. Nucleic Acids Res 33:D247-D251.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Pearl, F.1
Todd, A.2
Sillitoe, I.3
Dibley, M.4
Redfern, O.5
Lewis, T.6
Bennett, C.7
Marsden, R.8
Grant, A.9
Lee, D.10
-
26
-
-
0033835533
-
Structure-derived substitution matrices for alignment of distantly related sequences
-
Prlic A, Domingues FS, and Sippl MJ (2000) Structure-derived substitution matrices for alignment of distantly related sequences. Protein Eng 13:545-550.
-
(2000)
Protein Eng
, vol.13
, pp. 545-550
-
-
Prlic, A.1
Domingues, F.S.2
Sippl, M.J.3
-
27
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A and Blundell TL (1993) Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 234:779-815.
-
(1993)
J Mol Biol
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
29
-
-
0035967880
-
FUGUE: Sequence-structure homology recognition using environment- specific substitution tables and structure-dependent gap penalties
-
Shi J, Blundell TL, and Mizuguchi K (2001) FUGUE: sequence-structure homology recognition using environment- specific substitution tables and structure-dependent gap penalties. J Mol Biol 310:243-257.
-
(2001)
J Mol Biol
, vol.310
, pp. 243-257
-
-
Shi, J.1
Blundell, T.L.2
Mizuguchi, K.3
-
30
-
-
0028981088
-
A receptor subtypes
-
A receptor subtypes. Pharmacol Rev 47:181-234.
-
(1995)
Pharmacol Rev
, vol.47
, pp. 181-234
-
-
Sieghart, W.1
-
31
-
-
0036673411
-
Subunit composition, distribution and function of GABA(A) receptor subtypes
-
Sieghart W and Sperk G (2002) Subunit composition, distribution and function of GABA(A) receptor subtypes. Curr Top Med Chem 2:795-816.
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 795-816
-
-
Sieghart, W.1
Sperk, G.2
-
32
-
-
0031574072
-
The CLUSTAL_X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, and Higgins DG (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876-4882.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
33
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson JD, Higgins DG, and Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673-4680.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
34
-
-
0032976785
-
Residues in transmembrane domains I and II determine γ-aminobutyric acid type A receptor subtype-selective antagonism by furosemide
-
Thompson SA, Arden SA, Marshall G, Wingrove PB, Whiting PJ, and Wafford KA (1999) Residues in transmembrane domains I and II determine γ-aminobutyric acid type A receptor subtype-selective antagonism by furosemide. Mol Pharmacol 55:993-999.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 993-999
-
-
Thompson, S.A.1
Arden, S.A.2
Marshall, G.3
Wingrove, P.B.4
Whiting, P.J.5
Wafford, K.A.6
-
35
-
-
4143088670
-
Comparative modeling of a GABAA alpha1 receptor using three crystal structures as templates
-
Trudell JR and Bertaccini E (2004) Comparative modeling of a GABAA alpha1 receptor using three crystal structures as templates. J Mol Graph Model 23:39-49.
-
(2004)
J Mol Graph Model
, vol.23
, pp. 39-49
-
-
Trudell, J.R.1
Bertaccini, E.2
-
36
-
-
0242488935
-
Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy
-
Unwin N (2003) Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy. FEBS Lett 555:91-95.
-
(2003)
FEBS Lett
, vol.555
, pp. 91-95
-
-
Unwin, N.1
-
37
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
Unwin N (2005) Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J Mol Biol 346:967-989.
-
(2005)
J Mol Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
38
-
-
0036304564
-
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits
-
Unwin N, Miyazawa A, Li J, and Fujiyoshi Y (2002) Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits. J Mol Biol 319:1165-1176.
-
(2002)
J Mol Biol
, vol.319
, pp. 1165-1176
-
-
Unwin, N.1
Miyazawa, A.2
Li, J.3
Fujiyoshi, Y.4
-
39
-
-
0036759617
-
Structural evidence that propofol stabilizes different GABA(A) receptor states at potentiating and activating concentrations
-
Williams DB and Akabas MH (2002) Structural evidence that propofol stabilizes different GABA(A) receptor states at potentiating and activating concentrations. J Neurosci 22:7417-7424.
-
(2002)
J Neurosci
, vol.22
, pp. 7417-7424
-
-
Williams, D.B.1
Akabas, M.H.2
-
40
-
-
0029865892
-
Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit
-
Xu M and Akabas MH (1996) Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit. J Gen Physiol 107:195-205.
-
(1996)
J Gen Physiol
, vol.107
, pp. 195-205
-
-
Xu, M.1
Akabas, M.H.2
|