Molecular targets for the myorelaxant action of diazepam

Molecular Pharmacology

Volumn 59, Issue 3, 2001, Pages 442-445

  Crestani, Florence ^a   Löw, Karin ^a,b   Keist, Ruth ^a   Mandelli, Marie Juliette ^a,c   Möhler, Hanns ^a   Rudolph, Uwe ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DIAZEPAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG EFFECT; GABAERGIC TRANSMISSION; IMMUNOHISTOCHEMISTRY; LIMBIC SYSTEM; MOUSE; MUSCLE RELAXATION; MUSCLE TONE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR GENE; TARGET CELL;

EID: 0035122824     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.3.442     Document Type: Article

References (16)

1. A receptors: Classification on the basis of subunit structure and receptor function
2. A-receptor subtypes differentiated by their γ-subunit variants: Prevalence, pharmacology and subunit architecture
3. A receptors rendered diazepam-insensitive by point-mutated α-subunits
4. A-receptor subtypes in the spinal cord: An immunohistochemical study
5. Benzodiazepine antagonist Ro 15-1788: Neurological and behavioural effects
6. Benzodiazepines on trial: A research strategy for their rehabilitation
7. A-receptor heterogeneity in the adult brain: Differential regional and cellular distribution of seven major subunits
8. Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures
9. Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue
10. Molecular and neuronal substrate for the selective attenuation of anxiety
11. A-receptor subtypes really occur in the brain?
12. Abecarnil is a full agonist at some and a partial agonist at other recombinant gamma-aminobutyric acid Type A receptor subtypes
13. A receptor subtypes
14. Immunohistochemical mapping of gamma-aminobutyric acid type A receptor alpha subunits in rat central nervous system
15. A receptors is essential for benzodiazepine agonist binding