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Volumn 66, Issue 6, 1999, Pages 642-646

Effect of the gene dosage of CYP2C19 on diazepam metabolism in Chinese subjects

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C19; DIAZEPAM; NORDAZEPAM;

EID: 0033375477     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0009-9236(99)90075-9     Document Type: Article
Times cited : (96)

References (31)
  • 1
    • 0021237993 scopus 로고
    • Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man
    • 1. Küpfer A, Preisig R. Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man. Eur J Clin Pharmacol 1984;26:753-9.
    • (1984) Eur J Clin Pharmacol , vol.26 , pp. 753-759
    • Küpfer, A.1    Preisig, R.2
  • 3
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome p450 2c19: Correlation between 2c19 and s-mephenytoin 4′-hydroxylation
    • 3. Wrighton SA, Stevens JC, Becker GW, VanderBranden M. Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4′-hydroxylation. Arch Biochem Biophys 1993;306:240-5.
    • (1993) Arch Biochem Biophys , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    VanderBranden, M.4
  • 5
    • 0025572192 scopus 로고
    • Hydroxylation polymorphisms of debrisoquine and mephenytoin in european populations
    • 5. Alván G, Bechtel P, Iselius L, Gundert-Remy U. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations. Eur J Clin Pharmacol 1990;39: 533-7.
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 533-537
    • Alván, G.1    Bechtel, P.2    Iselius, L.3    Gundert-Remy, U.4
  • 6
    • 0029028932 scopus 로고
    • Geographic/interracial differences in polymorphic drug oxidation: Current state of knowledge of cytochrome p450 (cyp) 2d6 and 2c19
    • 6. Bertilsson L. Geographic/interracial differences in polymorphic drug oxidation: current state of knowledge of cytochrome P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 1995;29:192-209.
    • (1995) Clin Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 7
    • 0030012268 scopus 로고    scopus 로고
    • Genetic polymorphisms of debrisoquine and s-mephenytoin oxidation metabolism in chinese populations: A meta-analysis
    • 7. Xie HG, Xu ZH, Luo X, Huang SL, Zeng FD, Zhou HH. Genetic polymorphisms of debrisoquine and S-mephenytoin oxidation metabolism in Chinese populations: a meta-analysis. Pharmacogenetics 1996;6:235-8.
    • (1996) Pharmacogenetics , vol.6 , pp. 235-238
    • Xie, H.G.1    Xu, Z.H.2    Luo, X.3    Huang, S.L.4    Zeng, F.D.5    Zhou, H.H.6
  • 9
    • 8244249473 scopus 로고    scopus 로고
    • Differences in the incidence of the cyp2c19 polymorphism affecting the s-mephenytoin phenotype in chinese han and bai populations and identification of a new rare cyp2c19 mutant allele
    • 9. Xiao ZS, Goldstein JA, Xie HG, Blaisdell J, Wang W, Jiang CH, et al. Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele. J Pharmacol Exp Ther 1997;281:604-9.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 604-609
    • Xiao, Z.S.1    Goldstein, J.A.2    Xie, H.G.3    Blaisdell, J.4    Wang, W.5    Jiang, C.H.6
  • 10
    • 0024580554 scopus 로고
    • Importance of genetic factors in the regulation of diazepam metabolism: Relationship to s-mephenytoin, but not debrisoquine, hydroxylation phenotype
    • 10. Bertilsson L, Henthorn TK, Sanz E, Tybring G, Säwe EJ, Villén T. Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquine, hydroxylation phenotype. Clin Pharmacol Ther 1989;45:348-55.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 348-355
    • Bertilsson, L.1    Henthorn, T.K.2    Sanz, E.3    Tybring, G.4    Säwe, E.J.5    Villén, T.6
  • 11
    • 0025223056 scopus 로고
    • Diazepam metabolism in native chinese poor and extensive hydroxylators of s-mephenytoin: Interethnic differences in comparison with white subjects
    • 11. Zhang Y, Reviriego J, Lou YQ, Sjöqvist F, Bertilsson L. Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: interethnic differences in comparison with white subjects. Clin Pharmacol Ther 1990;48:496-502.
    • (1990) Clin Pharmacol Ther , vol.48 , pp. 496-502
    • Zhang, Y.1    Reviriego, J.2    Lou, Y.Q.3    Sjöqvist, F.4    Bertilsson, L.5
  • 12
    • 0026705708 scopus 로고
    • Incidence of s-mephenytoin hydroxylation deficiency in a korean population and the interphenotypic differences in diazepam pharmacokinetics
    • 12. Sohn DR, Kusaka M, Ishizaki T, Shin SG, Jang IJ, Shin JG, et al. Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics. Clin Pharmacol Ther 1992;52:160-9.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 160-169
    • Sohn, D.R.1    Kusaka, M.2    Ishizaki, T.3    Shin, S.G.4    Jang, I.J.5    Shin, J.G.6
  • 13
    • 0029842851 scopus 로고    scopus 로고
    • The elimination of diazepam in chinese subjects is dependent on the mephenytoin oxidation phenotype
    • 13. Wan J, Xia H, He N, Lu YQ, Zhou HH. The elimination of diazepam in Chinese subjects is dependent on the mephenytoin oxidation phenotype. Br J Clin Pharmacol 1996;42:471-4.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 471-474
    • Wan, J.1    Xia, H.2    He, N.3    Lu, Y.Q.4    Zhou, H.H.5
  • 14
    • 0027208084 scopus 로고
    • Why are diazepam metabolism and polymorphic s-mephenytoin hydroxylation associated with each other in white and korean populations but not in chinese populations?
    • 14. Bertilsson L, Kalow W. Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations? [letter]. Clin Pharmacol Ther 1993;53:608-10.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 608-610
    • Bertilsson, L.1    Kalow, W.2
  • 16
    • 0029587180 scopus 로고
    • Use of omeprazole as a probe drug for cyp2c19 phenotype in swedish caucasians: Comparison with s-mephenytoin hydroxylation phenotype and cyp2c19 genotype
    • 16. Chang M, Dahl ML, Tybring G, Gotharson E, Bertilsson L. Use of omeprazole as a probe drug for CYP2C19 phenotype in Swedish Caucasians: comparison with S-mephenytoin hydroxylation phenotype and CYP2C19 genotype. Pharmacogenetics 1995;5:358-63.
    • (1995) Pharmacogenetics , vol.5 , pp. 358-363
    • Chang, M.1    Dahl, M.L.2    Tybring, G.3    Gotharson, E.4    Bertilsson, L.5
  • 17
    • 0022212549 scopus 로고
    • Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation
    • 17. Küpfer A, Branch RA. Stereoselective mephobarbital hydroxylation cosegregates with mephenytoin hydroxylation. Clin Pharmacol Ther 1985;38:414-8.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 414-418
    • Küpfer, A.1    Branch, R.A.2
  • 18
    • 0028207548 scopus 로고
    • Stereoselective disposition of hexobarbital and its metabolites: Relationship to the s-mephenytoin polymorphism in caucasian and chinese subjects
    • 18. Adedoyin A, Prakash C, O'Shea D, Blair IA, Wilkinson GR. Stereoselective disposition of hexobarbital and its metabolites: relationship to the S-mephenytoin polymorphism in Caucasian and Chinese subjects. Pharmacogenetics 1994;4:27-38.
    • (1994) Pharmacogenetics , vol.4 , pp. 27-38
    • Adedoyin, A.1    Prakash, C.2    O'Shea, D.3    Blair, I.A.4    Wilkinson, G.R.5
  • 19
    • 0028228630 scopus 로고
    • In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by cyp3a4 isoforms as well as by s-mephenytoin hydroxylase
    • 19. Birkett DJ, Rees D, Andersson T, Gonzalez FJ, Miners JO, Veronese ME. In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A4 isoforms as well as by S-mephenytoin hydroxylase. Br J Clin Pharmacol 1994;37:413-20.
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 413-420
    • Birkett, D.J.1    Rees, D.2    Andersson, T.3    Gonzalez, F.J.4    Miners, J.O.5    Veronese, M.E.6
  • 20
    • 0030899603 scopus 로고    scopus 로고
    • Inhibition by omeprazole of proguanil metabolism: Mechanism of the interaction in vitro and prediction of in vivo results from the in vitro experiments
    • 20. Funck-Brentano C, Becquemont L, Leneveu A, Roux A, Jaillon P, Beaune P. Inhibition by omeprazole of proguanil metabolism: mechanism of the interaction in vitro and prediction of in vivo results from the in vitro experiments. J Pharmacol Exp Ther 1997;280:730-8.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 730-738
    • Funck-Brentano, C.1    Becquemont, L.2    Leneveu, A.3    Roux, A.4    Jaillon, P.5    Beaune, P.6
  • 21
    • 0031427039 scopus 로고    scopus 로고
    • Direct evidence for the higher frequency of cyp2c19 allelic heterozygotes in chinese subjects than in white subjects
    • 21. Xie HG. Direct evidence for the higher frequency of CYP2C19 allelic heterozygotes in Chinese subjects than in white subjects [letter]. Clin Pharmacol Ther 1997;62:691-2.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 691-692
    • Xie, H.G.1
  • 25
    • 0031787036 scopus 로고    scopus 로고
    • Relationship between proguanil metabolic ratio and cyp2c19 genotype in a caucasian population
    • 25. Hoskins JM, Shenfield GM, Gross AS. Relationship between proguanil metabolic ratio and CYP2C19 genotype in a Caucasian population. Br J Clin Pharmacol 1998;46:499-504.
    • (1998) Br J Clin Pharmacol , vol.46 , pp. 499-504
    • Hoskins, J.M.1    Shenfield, G.M.2    Gross, A.S.3
  • 26
    • 0030878213 scopus 로고    scopus 로고
    • Genetic polymorphism of cyp2c19 and lansoprazole pharmacokinetics in japanese subjects
    • 26. Katsuki H, Nakamura C, Arimori K, Fujiyama S, Nakano M. Genetic polymorphism of CYP2C19 and lansoprazole pharmacokinetics in Japanese subjects. Eur J Clin Pharmacol 1997;52:391-6.
    • (1997) Eur J Clin Pharmacol , vol.52 , pp. 391-396
    • Katsuki, H.1    Nakamura, C.2    Arimori, K.3    Fujiyama, S.4    Nakano, M.5
  • 27
    • 0021064223 scopus 로고
    • Pharmacokinetic model for diazepam and its major metabolite desmethyldiazepam following diazepam administration
    • 27. Jack ML, Colburn WA. Pharmacokinetic model for diazepam and its major metabolite desmethyldiazepam following diazepam administration. J Pharm Sci 1983;72: 1318-23.
    • (1983) J Pharm Sci , vol.72 , pp. 1318-1323
    • Jack, M.L.1    Colburn, W.A.2
  • 28
    • 0028589604 scopus 로고
    • Lack of low km diazepam n-demethylase in livers of poor metabolizers for s-mephenytoin 4′-hydroxylation
    • 28. Yasumori T, Li QH, Yamazoe Y, Ueda M, Tsuzaki T, Kato R. Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4′-hydroxylation. Pharmacogenetics 1994;4:323-31.
    • (1994) Pharmacogenetics , vol.4 , pp. 323-331
    • Yasumori, T.1    Li, Q.H.2    Yamazoe, Y.3    Ueda, M.4    Tsuzaki, T.5    Kato, R.6
  • 29
    • 0031034344 scopus 로고    scopus 로고
    • Diazepam metabolism by cdna-expressed hyman 2c p450s: Indentification of p4502c18 and p4502c19 as low km diazepam n-demethylase
    • 29. Jung F, Richardson TH, Raucy JL, Johnson EF. Diazepam metabolism by cDNA-expressed hyman 2C P450s: indentification of P4502C18 and P4502C19 as low Km diazepam N-demethylase. Drug Metab Dispos 1997;25: 133-9.
    • (1997) Drug Metab Dispos , vol.25 , pp. 133-139
    • Jung, F.1    Richardson, T.H.2    Raucy, J.L.3    Johnson, E.F.4
  • 31
    • 0030909951 scopus 로고    scopus 로고
    • Evidence for the effect of gender on activity of (s)-mephenytoin 4′-hydroxylase (cyp2c19) in a chinese population
    • 31. Xie HG, Huang SL, Xu ZH, Xiao ZS, He N, Zhou HH. Evidence for the effect of gender on activity of (S)-mephenytoin 4′-hydroxylase (CYP2C19) in a Chinese population. Pharmacogenetics 1997;7:115-9
    • (1997) Pharmacogenetics , vol.7 , pp. 115-119
    • Xie, H.G.1    Huang, S.L.2    Xu, Z.H.3    Xiao, Z.S.4    He, N.5    Zhou, H.H.6


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