메뉴 건너뛰기




Volumn 27, Issue 1, 1999, Pages 102-109

Eight inhibitory monoclonal antibodies define the role of individual P- 450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYIMIPRAMINE; 7 ETHOXYCOUMARIN; CYTOCHROME P450; DESIPRAMINE; DIAZEPAM; IMIPRAMINE; MONOCLONAL ANTIBODY; NORDAZEPAM; TEMAZEPAM;

EID: 0033010360     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (28)
  • 1
    • 0014771599 scopus 로고
    • Studies on the hydroxylation of 3,4-benzpyrene by hepatic microsomes: Effect of albumin on the rate of hydroxylation of 3,4-benzpyrene
    • Alvares AV, Schilling G, Garbut A and Kuntzman R (1970) Studies on the hydroxylation of 3,4-benzpyrene by hepatic microsomes: Effect of albumin on the rate of hydroxylation of 3,4-benzpyrene. Biochem Pharmacol 19:1449-1455.
    • (1970) Biochem Pharmacol , vol.19 , pp. 1449-1455
    • Alvares, A.V.1    Schilling, G.2    Garbut, A.3    Kuntzman, R.4
  • 2
    • 0030834105 scopus 로고    scopus 로고
    • Venlafaxine: In vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs. And effects on human hepatic CYP3A4, CYP2C9 and CYPIA2
    • Ball SE, Ahern D, Scatina J and Kao J (1997) Venlafaxine: In vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs. and effects on human hepatic CYP3A4, CYP2C9 and CYPIA2. Br J Clin Pharmacol 43:619-626.
    • (1997) Br J Clin Pharmacol , vol.43 , pp. 619-626
    • Ball, S.E.1    Ahern, D.2    Scatina, J.3    Kao, J.4
  • 3
    • 0028324344 scopus 로고
    • 7-ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensions
    • Bayliss MK, Bell JA, Wilson K and Park GR (1994) 7-Ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensions. Xenobiotica 24:231-241.
    • (1994) Xenobiotica , vol.24 , pp. 231-241
    • Bayliss, M.K.1    Bell, J.A.2    Wilson, K.3    Park, G.R.4
  • 4
    • 0027759647 scopus 로고
    • Cytochromc P450 and monoclonal antibodies
    • Gelboin HV (1993) Cytochromc P450 and monoclonal antibodies. Pharmacol Rev 45:413-453.
    • (1993) Pharmacol Rev , vol.45 , pp. 413-453
    • Gelboin, H.V.1
  • 7
    • 0009635380 scopus 로고    scopus 로고
    • Inhibitory monoclonal antibodies define the role of cytochrome P450 in human tissue: Polymorphically expressed P450 2D6 as paradigm
    • Gelboin HV, Krausz KW, Shou M, Gonzalez FJ and Yang TJ (1997) Inhibitory monoclonal antibodies define the role of cytochrome P450 in human tissue: Polymorphically expressed P450 2D6) as paradigm. Pharmacogenetics 7:467-477.
    • (1997) Pharmacogenetics , vol.7 , pp. 467-477
    • Gelboin, H.V.1    Krausz, K.W.2    Shou, M.3    Gonzalez, F.J.4    Yang, T.J.5
  • 8
    • 0024236331 scopus 로고
    • The molecular biology of cytochrome P450s
    • Gonzalez FJ (1988) The molecular biology of cytochrome P450s. Pharmacol Rev 40:243-288.
    • (1988) Pharmacol Rev , vol.40 , pp. 243-288
    • Gonzalez, F.J.1
  • 9
    • 0026324032 scopus 로고
    • Expression of mammalian cytochrome P450 using vaccinia virus
    • Gonzalez FJ, Aoyama T, and Gelboin HV (1991a) Expression of mammalian cytochrome P450 using vaccinia virus. Methods Enzymol 206:85-92.
    • (1991) Methods Enzymol , vol.206 , pp. 85-92
    • Gonzalez, F.J.1    Aoyama, T.2    Gelboin, H.V.3
  • 10
    • 0026082836 scopus 로고
    • CDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment
    • V, GH
    • Gonzalez FJ, Crespi CL and V, GH (1991b) cDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment. Mutat Res 247:113-127.
    • (1991) Mutat Res , vol.247 , pp. 113-127
    • Gonzalez, F.J.1    Crespi, C.L.2
  • 14
    • 0030898353 scopus 로고    scopus 로고
    • Imipramine demethylation in vivo: Impact of CYP1A2, CYP2C19, and CYP3A4
    • Madsen H, Rasmussen BB and Brosen K (1997) Imipramine demethylation in vivo: Impact of CYP1A2, CYP2C19, and CYP3A4. Clin Pharmacol Ther 61:319-324.
    • (1997) Clin Pharmacol Ther , vol.61 , pp. 319-324
    • Madsen, H.1    Rasmussen, B.B.2    Brosen, K.3
  • 16
    • 0027475463 scopus 로고
    • High-performance liquid chromatography of imipramine and six metabolites in human plasma and urine
    • Nielsen KK and Brosen K (1993) High-performance liquid Chromatography of imipramine and six metabolites in human plasma and urine. J Chromatogr 612:87-94.
    • (1993) J Chromatogr , vol.612 , pp. 87-94
    • Nielsen, K.K.1    Brosen, K.2
  • 17
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura T and Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239:2370-2378.
    • (1964) J Biol Chem , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 18
    • 0029974085 scopus 로고    scopus 로고
    • Human liver microsomal diazepam metabolism using cDNA-expressed cylochrome P450s: Role of CYP2B6, 2C19 and the 3A subfamily
    • Ono S, Hatanaka T, Miyazawa S, Tsutsui M, Aoyama T, Gonzalez FJ and Satoh T (1996) Human liver microsomal diazepam metabolism using cDNA-expressed cylochrome P450s: Role of CYP2B6, 2C19 and the 3A subfamily. Xenobiotica 26:1155-66.
    • (1996) Xenobiotica , vol.26 , pp. 1155-1166
    • Ono, S.1    Hatanaka, T.2    Miyazawa, S.3    Tsutsui, M.4    Aoyama, T.5    Gonzalez, F.J.6    Satoh, T.7
  • 19
    • 0020071879 scopus 로고
    • Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450
    • Park SS, Fujino T, West D, Guengerich FP and Gelboin HV (1982) Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450. Cancer Res 42:1798-808.
    • (1982) Cancer Res , vol.42 , pp. 1798-1808
    • Park, S.S.1    Fujino, T.2    West, D.3    Guengerich, F.P.4    Gelboin, H.V.5
  • 20
    • 0024456420 scopus 로고
    • Monoclonal antibodies to rat liver cytochrome P-450 2c/RLM5 that regiospecifically inhibit steroid metabolism
    • Park SS, Waxman DJ, Lapenson DP, Schenkman JB and Gelboin HV (1989) Monoclonal antibodies to rat liver cytochrome P-450 2c/RLM5 that regiospecifically inhibit steroid metabolism. Biochem Pharmacol 38:3067-74.
    • (1989) Biochem Pharmacol , vol.38 , pp. 3067-3074
    • Park, S.S.1    Waxman, D.J.2    Lapenson, D.P.3    Schenkman, J.B.4    Gelboin, H.V.5
  • 23
    • 0026750647 scopus 로고
    • The human hepatic cytochromes P450 involved in drug metabolism
    • Wrighton SA and Stevens JC (1992) The human hepatic cytochromes P450 involved in drug metabolism. Crit Rev Toxicol 22:1-21.
    • (1992) Crit Rev Toxicol , vol.22 , pp. 1-21
    • Wrighton, S.A.1    Stevens, J.C.2
  • 24
    • 0030064194 scopus 로고    scopus 로고
    • 7-ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes
    • Yamazaki H, Inoue K, Mimura M, Oda Y, Guengerich FP and Shimada T (1996) 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes. Biochem Pharmacol 51:313-9.
    • (1996) Biochem Pharmacol , vol.51 , pp. 313-319
    • Yamazaki, H.1    Inoue, K.2    Mimura, M.3    Oda, Y.4    Guengerich, F.P.5    Shimada, T.6
  • 26
    • 0031717524 scopus 로고    scopus 로고
    • Specific inhibitory monoclonal antibodies to human cytochrome P450 1A2: Analysis of phenacetin O-deethylalion in human liver
    • Yang TJ, Sai Y, Krausz KW, Gonzalez FJ and Gelboin HV (1998b) Specific inhibitory monoclonal antibodies to human cytochrome P450 1A2: Analysis of phenacetin O-deethylalion in human liver. Pharmacogenetics 8:375-382.
    • (1998) Pharmacogenetics , vol.8 , pp. 375-382
    • Yang, T.J.1    Sai, Y.2    Krausz, K.W.3    Gonzalez, F.J.4    Gelboin, H.V.5
  • 28
    • 0027744044 scopus 로고
    • Cytochrome P450 mediated metabolism of diazepam in human and rat: Involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner
    • Yasumori T, Nagata K, Yang SK, Chen L, Murayama N, Yamazoe Y and Kato R (1993) Cytochrome P450 mediated metabolism of diazepam in human and rat: Involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner. Pharmacogenetics 3:291-301.
    • (1993) Pharmacogenetics , vol.3 , pp. 291-301
    • Yasumori, T.1    Nagata, K.2    Yang, S.K.3    Chen, L.4    Murayama, N.5    Yamazoe, Y.6    Kato, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.