-
1
-
-
65249144557
-
Commonality but diversity in cancer gene fusions
-
Rabbitts T.H. Commonality but diversity in cancer gene fusions. Cell 2009, 137:391-395.
-
(2009)
Cell
, vol.137
, pp. 391-395
-
-
Rabbitts, T.H.1
-
2
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins S.A., et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005, 310:644-648.
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
-
3
-
-
77950947395
-
Mechanisms of chromosomal rearrangements in solid tumors: the model of papillary thyroid carcinoma
-
Gandhi M., et al. Mechanisms of chromosomal rearrangements in solid tumors: the model of papillary thyroid carcinoma. Mol. Cell Endocrinol. 2010, 321:36-43.
-
(2010)
Mol. Cell Endocrinol.
, vol.321
, pp. 36-43
-
-
Gandhi, M.1
-
4
-
-
42249102663
-
GammaH2AX foci form preferentially in euchromatin after ionising-radiation
-
Cowell I.G., et al. gammaH2AX foci form preferentially in euchromatin after ionising-radiation. PLoS One 2007, 2:e1057.
-
(2007)
PLoS One
, vol.2
-
-
Cowell, I.G.1
-
5
-
-
20744443773
-
Does radial nuclear organisation influence DNA damage?
-
Gazave E., et al. Does radial nuclear organisation influence DNA damage?. Chromosome Res. 2005, 13:377-388.
-
(2005)
Chromosome Res.
, vol.13
, pp. 377-388
-
-
Gazave, E.1
-
6
-
-
34447532525
-
Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals
-
Kim J.A., et al. Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. J. Cell Biol. 2007, 178:209-218.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 209-218
-
-
Kim, J.A.1
-
7
-
-
0031795051
-
Intrachromosomal localization of aberration breakpoints induced by neutrons and gamma rays in Chinese hamster ovary cells
-
Martinez-Lopez W., et al. Intrachromosomal localization of aberration breakpoints induced by neutrons and gamma rays in Chinese hamster ovary cells. Radiat. Res. 1998, 150:585-592.
-
(1998)
Radiat. Res.
, vol.150
, pp. 585-592
-
-
Martinez-Lopez, W.1
-
8
-
-
0024977417
-
Elevated recombination rates in transcriptionally active DNA
-
Thomas B.J., Rothstein R. Elevated recombination rates in transcriptionally active DNA. Cell 1989, 56:619-630.
-
(1989)
Cell
, vol.56
, pp. 619-630
-
-
Thomas, B.J.1
Rothstein, R.2
-
10
-
-
33646126725
-
Interphase chromosome folding determines spatial proximity of genes participating in carcinogenic RET/PTC rearrangements
-
Gandhi M., et al. Interphase chromosome folding determines spatial proximity of genes participating in carcinogenic RET/PTC rearrangements. Oncogene 2006, 25:2360-2366.
-
(2006)
Oncogene
, vol.25
, pp. 2360-2366
-
-
Gandhi, M.1
-
11
-
-
7444236477
-
Antigen receptor genes and the evolution of a recombinase
-
Schatz D.G. Antigen receptor genes and the evolution of a recombinase. Semin. Immunol. 2004, 16:245-256.
-
(2004)
Semin. Immunol.
, vol.16
, pp. 245-256
-
-
Schatz, D.G.1
-
12
-
-
42649123314
-
Mechanism and regulation of class switch recombination
-
Stavnezer J., et al. Mechanism and regulation of class switch recombination. Annu. Rev. Immunol. 2008, 26:261-292.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 261-292
-
-
Stavnezer, J.1
-
13
-
-
76249134265
-
Role of the translocation partner in protection against AID-dependent chromosomal translocations
-
Jankovic M., et al. Role of the translocation partner in protection against AID-dependent chromosomal translocations. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:187-192.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 187-192
-
-
Jankovic, M.1
-
14
-
-
57149146036
-
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
-
Robbiani D.F., et al. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 2008, 135:1028-1038.
-
(2008)
Cell
, vol.135
, pp. 1028-1038
-
-
Robbiani, D.F.1
-
15
-
-
70449641054
-
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations
-
Robbiani D.F., et al. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol. Cell 2009, 36:631-641.
-
(2009)
Mol. Cell
, vol.36
, pp. 631-641
-
-
Robbiani, D.F.1
-
16
-
-
57349185631
-
Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity
-
Tsai A.G., et al. Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell 2008, 135:1130-1142.
-
(2008)
Cell
, vol.135
, pp. 1130-1142
-
-
Tsai, A.G.1
-
17
-
-
77951893700
-
The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci
-
Ji Y., et al. The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. Cell 2010, 141:419-431.
-
(2010)
Cell
, vol.141
, pp. 419-431
-
-
Ji, Y.1
-
18
-
-
0037388165
-
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
-
Bransteitter R., et al. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:4102-4107.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 4102-4107
-
-
Bransteitter, R.1
-
19
-
-
0037926476
-
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
-
Pham P., et al. Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation. Nature 2003, 424:103-107.
-
(2003)
Nature
, vol.424
, pp. 103-107
-
-
Pham, P.1
-
20
-
-
0035150980
-
Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator
-
Tumbar T., Belmont A.S. Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator. Nat. Cell Biol. 2001, 3:134-139.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 134-139
-
-
Tumbar, T.1
Belmont, A.S.2
-
21
-
-
0035928736
-
Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus
-
Vazquez J., et al. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr. Biol. 2001, 11:1227-1239.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1227-1239
-
-
Vazquez, J.1
-
22
-
-
0031009827
-
Chromatin dynamics in interphase nuclei and its implications for nuclear structure
-
Abney J.R., et al. Chromatin dynamics in interphase nuclei and its implications for nuclear structure. J. Cell Biol. 1997, 137:1459-1468.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 1459-1468
-
-
Abney, J.R.1
-
23
-
-
0036006293
-
Chromatin motion is constrained by association with nuclear compartments in human cells
-
Chubb J.R., et al. Chromatin motion is constrained by association with nuclear compartments in human cells. Curr. Biol. 2002, 12:439-445.
-
(2002)
Curr. Biol.
, vol.12
, pp. 439-445
-
-
Chubb, J.R.1
-
24
-
-
12844253014
-
Dynamics of relative chromosome position during the cell cycle
-
Essers J., et al. Dynamics of relative chromosome position during the cell cycle. Mol. Biol. Cell 2005, 16:769-775.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 769-775
-
-
Essers, J.1
-
25
-
-
0345039879
-
Global chromosome positions are transmitted through mitosis in mammalian cells
-
Gerlich D., et al. Global chromosome positions are transmitted through mitosis in mammalian cells. Cell 2003, 112:751-764.
-
(2003)
Cell
, vol.112
, pp. 751-764
-
-
Gerlich, D.1
-
26
-
-
1142281997
-
The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1
-
Thomson I., et al. The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1. Curr. Biol. 2004, 14:166-172.
-
(2004)
Curr. Biol.
, vol.14
, pp. 166-172
-
-
Thomson, I.1
-
27
-
-
0037416135
-
Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages
-
Walter J., et al. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J. Cell Biol. 2003, 160:685-697.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 685-697
-
-
Walter, J.1
-
28
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
Dimitrova N., et al. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 2008, 456:524-528.
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
-
29
-
-
0346993718
-
Visualizing telomere dynamics in living mammalian cells using PNA probes
-
Molenaar C., et al. Visualizing telomere dynamics in living mammalian cells using PNA probes. EMBO J. 2003, 22:6631-6641.
-
(2003)
EMBO J.
, vol.22
, pp. 6631-6641
-
-
Molenaar, C.1
-
30
-
-
62849108417
-
Rapid telomere motions in live human cells analysed by highly time-resolved microscopy
-
Wang X., et al. Rapid telomere motions in live human cells analysed by highly time-resolved microscopy. Epigenetics Chromatin 2008, 1:4.
-
(2008)
Epigenetics Chromatin
, vol.1
, pp. 4
-
-
Wang, X.1
-
31
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak M.J., et al. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 2006, 172:823-834.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 823-834
-
-
Kruhlak, M.J.1
-
32
-
-
0032562595
-
In situ visualization of DNA double-strand break repair in human fibroblasts
-
Nelms B.E., et al. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 1998, 280:590-592.
-
(1998)
Science
, vol.280
, pp. 590-592
-
-
Nelms, B.E.1
-
33
-
-
10344225665
-
DNA breaks promote genomic instability by impeding proper chromosome segregation
-
Kaye J.A., et al. DNA breaks promote genomic instability by impeding proper chromosome segregation. Curr. Biol. 2004, 14:2096-2106.
-
(2004)
Curr. Biol.
, vol.14
, pp. 2096-2106
-
-
Kaye, J.A.1
-
34
-
-
10344240414
-
Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex
-
Lobachev K., et al. Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex. Curr. Biol. 2004, 14:2107-2112.
-
(2004)
Curr. Biol.
, vol.14
, pp. 2107-2112
-
-
Lobachev, K.1
-
35
-
-
34447574977
-
Positional stability of single double-strand breaks in mammalian cells
-
Soutoglou E., et al. Positional stability of single double-strand breaks in mammalian cells. Nat. Cell Biol. 2007, 9:675-682.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 675-682
-
-
Soutoglou, E.1
-
36
-
-
0347988236
-
Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
-
Aten J.A., et al. Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science 2004, 303:92-95.
-
(2004)
Science
, vol.303
, pp. 92-95
-
-
Aten, J.A.1
-
37
-
-
0037083376
-
Capturing chromosome conformation
-
Dekker J., et al. Capturing chromosome conformation. Science 2002, 295:1306-1311.
-
(2002)
Science
, vol.295
, pp. 1306-1311
-
-
Dekker, J.1
-
38
-
-
33745593972
-
Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence
-
Shopland L.S., et al. Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence. J. Cell Biol. 2006, 174:27-38.
-
(2006)
J. Cell Biol.
, vol.174
, pp. 27-38
-
-
Shopland, L.S.1
-
39
-
-
21844444077
-
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes
-
Bolzer A., et al. Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol. 2005, 3:e157.
-
(2005)
PLoS Biol.
, vol.3
-
-
Bolzer, A.1
-
40
-
-
33646729244
-
Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations
-
Branco M.R., Pombo A. Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLoS Biol. 2006, 4:e138.
-
(2006)
PLoS Biol.
, vol.4
-
-
Branco, M.R.1
Pombo, A.2
-
41
-
-
0031437119
-
Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
-
Brown K.E., et al. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 1997, 91:845-854.
-
(1997)
Cell
, vol.91
, pp. 845-854
-
-
Brown, K.E.1
-
42
-
-
19744379789
-
Nuclear re-organisation of the Hoxb complex during mouse embryonic development
-
Chambeyron S., et al. Nuclear re-organisation of the Hoxb complex during mouse embryonic development. Development 2005, 132:2215-2223.
-
(2005)
Development
, vol.132
, pp. 2215-2223
-
-
Chambeyron, S.1
-
43
-
-
0034703717
-
Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene
-
Lundgren M., et al. Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene. Cell 2000, 103:733-743.
-
(2000)
Cell
, vol.103
, pp. 733-743
-
-
Lundgren, M.1
-
44
-
-
33744779614
-
The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation
-
Ragoczy T., et al. The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev. 2006, 20:1447-1457.
-
(2006)
Genes Dev.
, vol.20
, pp. 1447-1457
-
-
Ragoczy, T.1
-
45
-
-
0035554683
-
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes
-
Skok J.A., et al. Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes. Nat. Immunol. 2001, 2:848-854.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 848-854
-
-
Skok, J.A.1
-
46
-
-
0028801067
-
Action at a distance: DNA-looping and initiation of transcription
-
Rippe K., et al. Action at a distance: DNA-looping and initiation of transcription. Trends Biochem. Sci. 1995, 20:500-506.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 500-506
-
-
Rippe, K.1
-
47
-
-
33745743206
-
Genome-wide scanning of HoxB1-associated loci in mouse ES cells using an open-ended chromosome conformation capture methodology
-
Wurtele H., Chartrand P. Genome-wide scanning of HoxB1-associated loci in mouse ES cells using an open-ended chromosome conformation capture methodology. Chromosome Res. 2006, 14:477-495.
-
(2006)
Chromosome Res.
, vol.14
, pp. 477-495
-
-
Wurtele, H.1
Chartrand, P.2
-
48
-
-
33750212321
-
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
-
Simonis M., et al. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat. Genet. 2006, 38:1348-1354.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1348-1354
-
-
Simonis, M.1
-
49
-
-
70349873824
-
Comprehensive mapping of long-range interactions reveals folding principles of the human genome
-
Lieberman-Aiden E., et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009, 326:289-293.
-
(2009)
Science
, vol.326
, pp. 289-293
-
-
Lieberman-Aiden, E.1
-
50
-
-
77952744854
-
A three-dimensional model of the yeast genome
-
Duan Z., et al. A three-dimensional model of the yeast genome. Nature 2010, 465:363-367.
-
(2010)
Nature
, vol.465
, pp. 363-367
-
-
Duan, Z.1
-
51
-
-
45149084413
-
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
-
Guelen L., et al. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature 2008, 453:948-951.
-
(2008)
Nature
, vol.453
, pp. 948-951
-
-
Guelen, L.1
-
52
-
-
38149133051
-
Transcription factories are nuclear subcompartments that remain in the absence of transcription
-
Mitchell J.A., Fraser P. Transcription factories are nuclear subcompartments that remain in the absence of transcription. Genes Dev. 2008, 22:20-25.
-
(2008)
Genes Dev.
, vol.22
, pp. 20-25
-
-
Mitchell, J.A.1
Fraser, P.2
-
53
-
-
45749154811
-
Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription
-
Palstra R.J., et al. Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription. PLoS One 2008, 3:e1661.
-
(2008)
PLoS One
, vol.3
-
-
Palstra, R.J.1
-
54
-
-
33750465872
-
SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
-
Cai S., et al. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat. Genet. 2006, 38:1278-1288.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1278-1288
-
-
Cai, S.1
-
55
-
-
5444255213
-
The active spatial organization of the beta-globin locus requires the transcription factor EKLF
-
Drissen R., et al. The active spatial organization of the beta-globin locus requires the transcription factor EKLF. Genes Dev. 2004, 18:2485-2490.
-
(2004)
Genes Dev.
, vol.18
, pp. 2485-2490
-
-
Drissen, R.1
-
56
-
-
33746063711
-
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
-
Kurukuti S., et al. CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:10684-10689.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10684-10689
-
-
Kurukuti, S.1
-
57
-
-
5444237577
-
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
-
Spilianakis C.G., Flavell R.A. Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat. Immunol. 2004, 5:1017-1027.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1017-1027
-
-
Spilianakis, C.G.1
Flavell, R.A.2
-
58
-
-
33748259774
-
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus
-
Splinter E., et al. CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev. 2006, 20:2349-2354.
-
(2006)
Genes Dev.
, vol.20
, pp. 2349-2354
-
-
Splinter, E.1
-
59
-
-
0036923833
-
Looping and interaction between hypersensitive sites in the active beta-globin locus
-
Tolhuis B., et al. Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol. Cell 2002, 10:1453-1465.
-
(2002)
Mol. Cell
, vol.10
, pp. 1453-1465
-
-
Tolhuis, B.1
-
60
-
-
0033565525
-
Collisions between yeast chromosomal loci in vivo are governed by three layers of organization
-
Burgess S.M., Kleckner N. Collisions between yeast chromosomal loci in vivo are governed by three layers of organization. Genes Dev. 1999, 13:1871-1883.
-
(1999)
Genes Dev.
, vol.13
, pp. 1871-1883
-
-
Burgess, S.M.1
Kleckner, N.2
-
61
-
-
40849105359
-
Examination of interchromosomal interactions in vegetatively growing diploid Schizosaccharomyces pombe cells by Cre/loxP site-specific recombination
-
Molnar M., Kleckner N. Examination of interchromosomal interactions in vegetatively growing diploid Schizosaccharomyces pombe cells by Cre/loxP site-specific recombination. Genetics 2008, 178:99-112.
-
(2008)
Genetics
, vol.178
, pp. 99-112
-
-
Molnar, M.1
Kleckner, N.2
-
62
-
-
3543111494
-
An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster
-
Egli D., et al. An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster. Genome Res. 2004, 14:1382-1393.
-
(2004)
Genome Res.
, vol.14
, pp. 1382-1393
-
-
Egli, D.1
-
63
-
-
0033985437
-
Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications
-
Zheng B., et al. Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications. Mol. Cell Biol. 2000, 20:648-655.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 648-655
-
-
Zheng, B.1
-
64
-
-
0030454561
-
Engineering the Drosophila genome: chromosome rearrangements by design
-
Golic K.G., Golic M.M. Engineering the Drosophila genome: chromosome rearrangements by design. Genetics 1996, 144:1693-1711.
-
(1996)
Genetics
, vol.144
, pp. 1693-1711
-
-
Golic, K.G.1
Golic, M.M.2
-
65
-
-
0035810931
-
Regulated transposition of a fish transposon in the mouse germ line
-
Fischer S.E., et al. Regulated transposition of a fish transposon in the mouse germ line. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:6759-6764.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 6759-6764
-
-
Fischer, S.E.1
-
66
-
-
13144261694
-
Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells
-
Luo G., et al. Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:10769-10773.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 10769-10773
-
-
Luo, G.1
-
67
-
-
68149180869
-
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice
-
Kokubu C., et al. A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice. Nat. Genet. 2009, 41:946-952.
-
(2009)
Nat. Genet.
, vol.41
, pp. 946-952
-
-
Kokubu, C.1
-
68
-
-
33845986339
-
Spatial genome organization in the formation of chromosomal translocations
-
Meaburn K.J., et al. Spatial genome organization in the formation of chromosomal translocations. Semin. Cancer Biol. 2007, 17:80-90.
-
(2007)
Semin. Cancer Biol.
, vol.17
, pp. 80-90
-
-
Meaburn, K.J.1
-
69
-
-
0036968594
-
Influences of chromosome size, gene density and nuclear position on the frequency of constitutional translocations in the human population
-
Bickmore W.A., Teague P. Influences of chromosome size, gene density and nuclear position on the frequency of constitutional translocations in the human population. Chromosome Res. 2002, 10:707-715.
-
(2002)
Chromosome Res.
, vol.10
, pp. 707-715
-
-
Bickmore, W.A.1
Teague, P.2
-
70
-
-
4844223232
-
Tissue-specific spatial organization of genomes
-
Parada L.A., et al. Tissue-specific spatial organization of genomes. Genome Biol. 2004, 5:R44.
-
(2004)
Genome Biol.
, vol.5
-
-
Parada, L.A.1
-
71
-
-
0036795327
-
Conservation of relative chromosome positioning in normal and cancer cells
-
Parada L.A., et al. Conservation of relative chromosome positioning in normal and cancer cells. Curr. Biol. 2002, 12:1692-1697.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1692-1697
-
-
Parada, L.A.1
-
72
-
-
0343484918
-
The topological organization of chromosomes 9 and 22 in cell nuclei has a determinative role in the induction of t(9,22) translocations and in the pathogenesis of t(9,22) leukemias
-
Kozubek S., et al. The topological organization of chromosomes 9 and 22 in cell nuclei has a determinative role in the induction of t(9,22) translocations and in the pathogenesis of t(9,22) leukemias. Chromosoma 1999, 108:426-435.
-
(1999)
Chromosoma
, vol.108
, pp. 426-435
-
-
Kozubek, S.1
-
73
-
-
2642674401
-
Localisation and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukaemia
-
Lukasova E., et al. Localisation and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukaemia. Hum. Genet. 1997, 100:525-535.
-
(1997)
Hum. Genet.
, vol.100
, pp. 525-535
-
-
Lukasova, E.1
-
74
-
-
0033557569
-
The nuclear topography of ABL, BCR, PML, and RARalpha genes: evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation
-
Neves H., et al. The nuclear topography of ABL, BCR, PML, and RARalpha genes: evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation. Blood 1999, 93:1197-1207.
-
(1999)
Blood
, vol.93
, pp. 1197-1207
-
-
Neves, H.1
-
75
-
-
0034613291
-
Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells
-
Nikiforova M.N., et al. Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. Science 2000, 290:138-141.
-
(2000)
Science
, vol.290
, pp. 138-141
-
-
Nikiforova, M.N.1
-
76
-
-
34548210885
-
Myc dynamically and preferentially relocates to a transcription factory occupied by Igh
-
Osborne C.S., et al. Myc dynamically and preferentially relocates to a transcription factory occupied by Igh. PLoS Biol. 2007, 5:e192.
-
(2007)
PLoS Biol.
, vol.5
-
-
Osborne, C.S.1
-
77
-
-
16844364396
-
Proximity of TPR and NTRK1 rearranging loci in human thyrocytes
-
Roccato E., et al. Proximity of TPR and NTRK1 rearranging loci in human thyrocytes. Cancer Res. 2005, 65:2572-2576.
-
(2005)
Cancer Res.
, vol.65
, pp. 2572-2576
-
-
Roccato, E.1
-
78
-
-
0038054340
-
Spatial proximity of translocation-prone gene loci in human lymphomas
-
Roix J.J., et al. Spatial proximity of translocation-prone gene loci in human lymphomas. Nat. Genet. 2003, 34:287-291.
-
(2003)
Nat. Genet.
, vol.34
, pp. 287-291
-
-
Roix, J.J.1
-
79
-
-
67650457059
-
Mechanisms promoting translocations in editing and switching peripheral B cells
-
Wang J.H., et al. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature 2009, 460:231-236.
-
(2009)
Nature
, vol.460
, pp. 231-236
-
-
Wang, J.H.1
-
80
-
-
71249101060
-
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
-
Lin C., et al. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 2009, 139:1069-1083.
-
(2009)
Cell
, vol.139
, pp. 1069-1083
-
-
Lin, C.1
-
81
-
-
70849135782
-
Induced chromosomal proximity and gene fusions in prostate cancer
-
Mani R.S., et al. Induced chromosomal proximity and gene fusions in prostate cancer. Science 2009, 326:1230.
-
(2009)
Science
, vol.326
, pp. 1230
-
-
Mani, R.S.1
-
82
-
-
60549088880
-
Chromosomal location targets different MYC family gene members for oncogenic translocations
-
Gostissa M., et al. Chromosomal location targets different MYC family gene members for oncogenic translocations. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:2265-2270.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 2265-2270
-
-
Gostissa, M.1
-
83
-
-
41149162677
-
Leukaemia lineage specification caused by cell-specific Mll-Enl translocations
-
Cano F., et al. Leukaemia lineage specification caused by cell-specific Mll-Enl translocations. Oncogene 2008, 27:1945-1950.
-
(2008)
Oncogene
, vol.27
, pp. 1945-1950
-
-
Cano, F.1
-
84
-
-
77951836633
-
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis
-
Baranzini S.E., et al. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature 2010, 464:1351-1356.
-
(2010)
Nature
, vol.464
, pp. 1351-1356
-
-
Baranzini, S.E.1
-
85
-
-
34548441098
-
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution
-
Bignell G.R., et al. Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. Genome Res. 2007, 17:1296-1303.
-
(2007)
Genome Res.
, vol.17
, pp. 1296-1303
-
-
Bignell, G.R.1
-
86
-
-
46449095106
-
Mapping translocation breakpoints by next-generation sequencing
-
Chen W., et al. Mapping translocation breakpoints by next-generation sequencing. Genome Res. 2008, 18:1143-1149.
-
(2008)
Genome Res.
, vol.18
, pp. 1143-1149
-
-
Chen, W.1
-
87
-
-
35348988679
-
Paired-end mapping reveals extensive structural variation in the human genome
-
Korbel J.O., et al. Paired-end mapping reveals extensive structural variation in the human genome. Science 2007, 318:420-426.
-
(2007)
Science
, vol.318
, pp. 420-426
-
-
Korbel, J.O.1
-
88
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance E.D., et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 2010, 463:191-196.
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
-
89
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance E.D., et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 2010, 463:184-190.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
-
90
-
-
34250334695
-
Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs)
-
Ruan Y., et al. Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs). Genome Res. 2007, 17:828-838.
-
(2007)
Genome Res.
, vol.17
, pp. 828-838
-
-
Ruan, Y.1
-
91
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
Stephens P.J., et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009, 462:1005-1010.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
-
92
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L., et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010, 464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
-
93
-
-
44349191457
-
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
-
Campbell P.J., et al. Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat. Genet. 2008, 40:722-729.
-
(2008)
Nat. Genet.
, vol.40
, pp. 722-729
-
-
Campbell, P.J.1
-
94
-
-
66749169417
-
Chromosome instability is common in human cleavage-stage embryos
-
Vanneste E., et al. Chromosome instability is common in human cleavage-stage embryos. Nat. Med. 2009, 15:577-583.
-
(2009)
Nat. Med.
, vol.15
, pp. 577-583
-
-
Vanneste, E.1
-
95
-
-
65849336044
-
At loose ends: resecting a double-strand break
-
Bernstein K.A., Rothstein R. At loose ends: resecting a double-strand break. Cell 2009, 137:807-810.
-
(2009)
Cell
, vol.137
, pp. 807-810
-
-
Bernstein, K.A.1
Rothstein, R.2
-
96
-
-
0345307262
-
The Sleeping Beauty transposable element: evolution, regulation and genetic applications
-
Ivics Z., et al. The Sleeping Beauty transposable element: evolution, regulation and genetic applications. Curr. Issues Mol. Biol. 2004, 6:43-55.
-
(2004)
Curr. Issues Mol. Biol.
, vol.6
, pp. 43-55
-
-
Ivics, Z.1
-
97
-
-
0034621854
-
Frequent chromosomal translocations induced by DNA double-strand breaks
-
Richardson C., Jasin M. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 2000, 405:697-700.
-
(2000)
Nature
, vol.405
, pp. 697-700
-
-
Richardson, C.1
Jasin, M.2
-
98
-
-
33750203582
-
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
-
Zhao Z., et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat. Genet. 2006, 38:1341-1347.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1341-1347
-
-
Zhao, Z.1
-
99
-
-
33749400168
-
Chromosome conformation capture carbon copy (5C): a massively parallel solution for mapping interactions between genomic elements
-
Dostie J., et al. Chromosome conformation capture carbon copy (5C): a massively parallel solution for mapping interactions between genomic elements. Genome Res. 2006, 16:1299-1309.
-
(2006)
Genome Res.
, vol.16
, pp. 1299-1309
-
-
Dostie, J.1
|