Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes

International Journal of Molecular Medicine

Volumn 20, Issue 6, 2007, Pages 783-792

  Drel, Viktor R ^a   Pacher, Pal ^b   Vareniuk, Igor ^a   Pavlov, Ivan A ^a   Ilnytska, Olga ^a   Lyzogubov, Valeriy V ^a   Bell, Seth R ^c   Groves, John T ^c   Obrosova, Irina G ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c PRINCETON UNIVERSITY   (United States)

Author keywords

Nerve conduction; Nitrosative stress; Peripheral diabetic neuropathy; Peroxynitrite decomposition catalysts; Poly(ADP ribose) polymerase

Indexed keywords

5,10,15,20 TETRAKIS(2,4,6 TRIMETHYL 3,3 DISULFONATOPHENYL)PORPHYRINATO IRON(III); 5,10,15,20-TETRAKIS(2,4,6-TRIMETHYL-3,3-DISULFONATOPHENYL)PORPHYRINATO IRON(III); FERRIC ION; METALLOPORPHYRIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXYNITROUS ACID; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL BEHAVIOR; ARTICLE; C57BL MOUSE; CHEMISTRY; DIABETIC NEUROPATHY; DISEASE MODEL; EVALUATION; EXPERIMENTAL DIABETES MELLITUS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; MOUSE; NERVE CONDUCTION; OXIDATIVE STRESS; PHYSIOLOGY; SCIATIC NERVE;

ANIMALS; BEHAVIOR, ANIMAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; FERRIC COMPOUNDS; HUMANS; METALLOPORPHYRINS; MICE; MICE, INBRED C57BL; NEURAL CONDUCTION; OXIDATIVE STRESS; PEROXYNITROUS ACID; POLY(ADP-RIBOSE) POLYMERASES; SCIATIC NERVE;

EID: 42149132763     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.20.6.783     Document Type: Article

References (42)

1. Boulton AJ, Vinik AI, Arezzo JC, Bril V, Feldman EL, Freeman R, Malik RA, Maser RE, Sosenko JM and Ziegler D: American Diabetes Association. Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care 28: 956-962, 2005.
2. Nagamatsu M, Nickander KK, Schmelzer JD, Raya A, Wittrock DA, Tritschler H and Low PA: Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care 18: 1160-1167, 1995.
3. Cameron NE, Tuck Z, McCabe L and Cotter MA: Effect of the hydroxyl radical scavenger, dimethylthiourea, on peripheral nerve tissue perfusion, conduction velocity and nociception in experimental diabetes. Diabetologia 44: 1161-1169, 2001.
4. Coppey LJ, Gellett JS, Davidson EP, Dunlap JA, Lund DD and Yorek MA: Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 50: 1927-1937, 2001.
5. Pacher P, Beckman JS and Liaudet L: Nitric oxide and peroxynitrite in health and disease. Physiol Rev 87: 315-424, 2007.
6. Hoeldtke RD: Nitrosative stress in early Type 1 diabetes. David H.P. Streeten Memorial Lecture. Clin Auton Res 13: 406-421, 2003.
7. Ceriello A, Piconi L, Esposito K and Giugliano D: Telmisartan shows an equivalent effect of vitamin C in further improving endothelial dysfunction after glycemia normalization in type 1 diabetes. Diabetes Care 30: 1694-1698, 2007. (Pubitemid 47036338)
8. Ziegler D, Sohr CG and Nourooz-Zadeh J: Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy. Diabetes Care 27: 2178-2183, 2004.
9. Nangle MR, Cotter MA and Cameron NE: Effects of the peroxynitrite decomposition catalyst, FeTMPyP, on function of corpus cavernosum from diabetic mice. Eur J Pharmacol 502: 143-148, 2004.
10. Obrosova IG, Mabley JG, Zsengeller Z, Charniauskaya T, Abatan OI, Groves JT and Szabo C: Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst. FASEB J 19: 401-403, 2005.
11. Shimanovich R and Groves JT: Mechanisms of peroxynitrite decomposition catalyzed by FeTMPS, a bioactive sulfonated iron porphyrin. Arch Biochem Biophys 387: 307-317, 2001.
12. Garcia Soriano F, Virag L, Jagtap P, Szabo E, Mabley JG, Liaudet L, Marton A, Hoyt DG, Murthy KG, Salzman AL, Southan GJ and Szabo C: Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med 7: 108-113, 2001.
13. Jagtap P and Szabo C: Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4: 421-440, 2005.
14. Andrabi SA, Kim NS, Yu SW, Wang H, Koh DW, Sasaki M, Klaus JA, Otsuka T, Zhang Z, Koehler RC, Hurn PD, Poirier GG, Dawson VL and Dawson TM: Poly(ADP-ribose) (PAR) polymer is a death signal. Proc Natl Acad Sci USA 103: 18308-18313, 2006.
15. Obrosova IG, Li F, Abatan OI, Forsell MA, Komjati K, Pacher P, Szabo C and Stevens MJ: Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy. Diabetes 53: 711-720, 2004.
16. Ilnytska O, Lyzogubov VV, Stevens MJ, Drel VR, Mashtalir N, Pacher P, Yorek MA and Obrosova IG: Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy. Diabetes 55: 1686-1694, 2006.
17. Drel VR, Mashtalir N, Ilnytska O, Shin J, Li F, Lyzogubov VV and Obrosova IG: The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of type 2 diabetes and obesity. Diabetes 55: 3335-3343, 2006.
18. Levrand S, Vannay-Bouchiche C, Pesse B, Pacher P, Feihl F, Waeber B and Liaudet L: Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo. Free Radic Biol Med 41: 886-895, 2006.
19. Obrosova IG, Pacher P, Szabo C, Zsengeller Z, Hirooka H, Stevens MJ and Yorek MA: Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications. Diabetes 54: 234-242, 2005. (Pubitemid 40105118)
20. Cheng C and Zochodne DW: Sensory neurons with activated caspase-3 survive long-term experimental diabetes. Diabetes 52: 2363-2371, 2003.
21. Schmeichel AM, Schmelzer JD and Low PA: Oxidative injury and apoptosis of dorsal root ganglion neurons in chronic experimental diabetic neuropathy. Diabetes 52: 165-171, 2003.
22. Yagihashi S, Yamagishi SI, Wada Ri R, Baba M, Hohman TC, Yabe-Nishimura C and Kokai Y: Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor. Brain 124: 2448-2458, 2001.
23. Christianson JA, Riekhof JT and Wright DE: Restorative effects of neurotrophin treatment on diabetes-induced cutaneous axon loss in mice. Exp Neurol 179: 188-199, 2003.
24. Ho EC, Lam KS, Chen YS, Yip JC, Arvindakshan M, Yamagishi S, Yagihashi S, Oates PJ, Ellery CA, Chung SS and Chung SK: Aldose reductase-deficient mice are protected from delayed motor nerve conduction velocity, increased c-Jun NH2-terminal kinase activation, depletion of reduced glutathione, increased superoxide accumulation, and DNA damage. Diabetes 55: 1946-1953, 2006.
25. Kato N, Mizuno K, Makino M, Suzuki T and Yagihashi S: Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats. Diabetes Res Clin Pract 50: 77-85, 2000.
26. Stevens MJ, Zhang W, Li F and Sima AA: C-peptide corrects endoneurial blood flow but not oxidative stress in type 1 BB/Wor rats. Am J Physiol Endocrinol Metab 287: E497-E505, 2004.
27. Cameron NE, Eaton SE, Cotter MA and Tesfaye S: Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 44: 1973-1988, 2001.
28. Obrosova IG: Update on the pathogenesis of diabetic neuropathy. Curr Diabetes Rep 3: 439-445, 2003.
29. Obrosova IG, Lyzogubov V, Ilnytska O, Mashtalir N, Vareniuk I, Pavlov I, Xu W, Zhang J and Drel VR: PARP inhibition or gene deficiency counteract intraepidermal nerve fiber loss and neuropathic pain associated with Type 1 diabetes. Diabetes 56 (suppl 1): A1, 2007.
30. Dyck PJ, Dyck PJ, Larson TS, O'Brien PC and Velosa JA: Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy: a study of three cohorts. Nerve growth factor study group. Diabetes Care 23: 510-517, 2000.
31. Stevens MJ, Li F, Drel VR, Abatan OI, Kim H, Burnett D, Larkin D and Obrosova IG: Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats. J Pharmacol Exp Ther 320: 458-464, 2007. (Pubitemid 46025758)
32. Vinik AI, Suwanwalaikorn S, Stansberry KB, Holland MT, McNitt PM and Colen LE: Quantitative measurement of cutaneous perception in diabetic neuropathy. Muscle Nerve 18: 574-584, 1995.
33. Christianson JA, Ryals JM, Johnson MS, Dobrowsky RT and Wright DE: Neurotrophic modulation of myelinated cutaneous innervation and mechanical sensory loss in diabetic mice. Neuroscience 145: 303-313, 2007.
34. Sumner CJ, Sheth S, Griffin JW, Cornblath DR and Polydefkis M: The spectrum of neuropathy in diabetes and impaired glucose tolerance. Neurology 60: 108-111, 2003.
35. Pittenger G, Burkus N, McNulty P, Basta B and Vinik A: Intraepidermal nerve fibers are indicators of small fiber neuropathy in both diabetic and non-diabetic patients. Diabetes Care 27: 1974-1979, 2004.
36. Toth C, Brussee V and Zochodne DW: Remote neurotrophic support of epidermal nerve fibres in experimental diabetes. Diabetologia 49: 1081-1088, 2006.
37. Vinik AI, Ullal J, Parson HK, Barlow PM and Casellini CM: Pioglitazone treatment improves nitrosative stress in type 2 diabetes. Diabetes Care 29: 869-876, 2006.
38. Szabo C, Zanchi A, Komjati K, Pacher P, Krolewski AS, Quist WC, LoGerfo FW, Horton ES and Veves A: Poly(ADP-ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity. Circulation 106: 2680-2686, 2002.
39. Ha HC, Hester LD and Snyder SH: Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia. Proc Natl Acad Sci USA 99: 3270-3275, 2002.
40. Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM and Dawson VL: Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297: 259-263, 2002.
41. Vareniuk I, Pavlov IA, Drel VR, Lyzogubov VV, Ilnytska O, Bell SR, Tibrewala J, Groves JT and Obrosova IG: Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice. Exp Neurol 205: 425-436, 2007.
42. Sima AA and Kamiya H: Diabetic neuropathy differs in type 1 and type 2 diabetes. Ann NY Acad Sci 1084: 235-249, 2006.