메뉴 건너뛰기




Volumn 55, Issue 6, 2006, Pages 1686-1694

Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy

Author keywords

DRG, dorsal root ganglia; ISO, 1,5 isoquinolinediol; PARP, poly(ADP ribose) polymerase; STZ, streptozotocin; TUNEL, transferase mediated dUTP nick end labeling

Indexed keywords

GLUCOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 33748292845     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0067     Document Type: Article
Times cited : (126)

References (51)
  • 1
    • 0034038502 scopus 로고    scopus 로고
    • Effects of DL-α-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy
    • Stevens MJ, Obrosova I, Cao X, Van Huysen C, Greene DA: Effects of DL-α-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy. Diabetes 49:1006-1015, 2000
    • (2000) Diabetes , vol.49 , pp. 1006-1015
    • Stevens, M.J.1    Obrosova, I.2    Cao, X.3    Van Huysen, C.4    Greene, D.A.5
  • 2
    • 0035430412 scopus 로고    scopus 로고
    • Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve
    • Coppey LJ, Gellett JS, Davidson EP, Dunlap JA, Lund DD, Yorek MA: Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 50:1927-1937, 2001
    • (2001) Diabetes , vol.50 , pp. 1927-1937
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Dunlap, J.A.4    Lund, D.D.5    Yorek, M.A.6
  • 3
    • 0034741718 scopus 로고    scopus 로고
    • Effect of the hydroxyl radical scavenger, dimethylthiourea, on peripheral nerve tissue perfusion, conduction velocity and nociception in experimental diabetes
    • Cameron NE, Tuck Z, McCabe L, Cotter MA: Effect of the hydroxyl radical scavenger, dimethylthiourea, on peripheral nerve tissue perfusion, conduction velocity and nociception in experimental diabetes. Diabetologia 44:1161-1169, 2001
    • (2001) Diabetologia , vol.44 , pp. 1161-1169
    • Cameron, N.E.1    Tuck, Z.2    McCabe, L.3    Cotter, M.A.4
  • 4
    • 14644405532 scopus 로고    scopus 로고
    • Role for nitrosative stress in diabetic neuropathy: Evidence from studies with a peroxynitrite decomposition catalyst
    • Obrosova IG, Mabley JG, Zsengeller Z, Charniauskaya T, Abatan OI, Groves JT, Szabo C: Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst. FASEB J 19:401-403, 2005
    • (2005) FASEB J , vol.19 , pp. 401-403
    • Obrosova, I.G.1    Mabley, J.G.2    Zsengeller, Z.3    Charniauskaya, T.4    Abatan, O.I.5    Groves, J.T.6    Szabo, C.7
  • 6
    • 0035054480 scopus 로고    scopus 로고
    • Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy
    • Hounsom L, Corder R, Patel J, Tomlinson DR: Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. Diabetologia 44:424-428, 2001
    • (2001) Diabetologia , vol.44 , pp. 424-428
    • Hounsom, L.1    Corder, R.2    Patel, J.3    Tomlinson, D.R.4
  • 7
    • 0035132956 scopus 로고    scopus 로고
    • Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: Modulation by nitecapone, a COMT inhibitor with antioxidant properties
    • Pertovaara A, Wei H, Kalmari J, Ruotsalainen M: Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: modulation by nitecapone, a COMT inhibitor with antioxidant properties. Exp Neurol 167:425-434, 2001
    • (2001) Exp Neurol , vol.167 , pp. 425-434
    • Pertovaara, A.1    Wei, H.2    Kalmari, J.3    Ruotsalainen, M.4
  • 9
    • 2442701767 scopus 로고    scopus 로고
    • Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor
    • Calcutt NA, Freshwater JD, Mizisin AP: Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor. Diabetologia 47:718-724, 2004
    • (2004) Diabetologia , vol.47 , pp. 718-724
    • Calcutt, N.A.1    Freshwater, J.D.2    Mizisin, A.P.3
  • 12
    • 0036303144 scopus 로고    scopus 로고
    • Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats
    • Freshwater JD, Svensson CI, Malmberg AB, Calcutt NA: Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes 51:2249-2255, 2002
    • (2002) Diabetes , vol.51 , pp. 2249-2255
    • Freshwater, J.D.1    Svensson, C.I.2    Malmberg, A.B.3    Calcutt, N.A.4
  • 16
    • 0036064154 scopus 로고    scopus 로고
    • The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes
    • Pacher P, Liaudet L, Soriano FG, Mabley JG, Szabo E, Szabo C: The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes 51:514-521, 2002
    • (2002) Diabetes , vol.51 , pp. 514-521
    • Pacher, P.1    Liaudet, L.2    Soriano, F.G.3    Mabley, J.G.4    Szabo, E.5    Szabo, C.6
  • 17
    • 7044229731 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB
    • Zheng L, Szabo C, Kern TS: Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB. Diabetes 53:2960-2967, 2004
    • (2004) Diabetes , vol.53 , pp. 2960-2967
    • Zheng, L.1    Szabo, C.2    Kern, T.S.3
  • 19
    • 2442651710 scopus 로고    scopus 로고
    • Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy
    • Li F, Szabo C, Pacher P, Southan GJ, Abatan OI, Charniauskaya T, Stevens MJ, Obrosova IG: Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy. Diabetologia 47:710-717, 2004
    • (2004) Diabetologia , vol.47 , pp. 710-717
    • Li, F.1    Szabo, C.2    Pacher, P.3    Southan, G.J.4    Abatan, O.I.5    Charniauskaya, T.6    Stevens, M.J.7    Obrosova, I.G.8
  • 20
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
    • Virag L, Szabo C: The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54:375-429, 2002
    • (2002) Pharmacol Rev , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 21
    • 0032858197 scopus 로고    scopus 로고
    • Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: A prevention study
    • Obrosova IG, Fathallah L, Lang HJ, Greene DA: Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study. Diabetologia 42:1187-1194, 1999
    • (1999) Diabetologia , vol.42 , pp. 1187-1194
    • Obrosova, I.G.1    Fathallah, L.2    Lang, H.J.3    Greene, D.A.4
  • 22
    • 0033760829 scopus 로고    scopus 로고
    • Diabetic peripheral neuropathy: Evidence for apoptosis and associated mitochondrial dysfunction
    • Srinivasan S, Stevens M, Wiley JW: Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction. Diabetes 49:1932-1938, 2000
    • (2000) Diabetes , vol.49 , pp. 1932-1938
    • Srinivasan, S.1    Stevens, M.2    Wiley, J.W.3
  • 23
    • 2942709609 scopus 로고    scopus 로고
    • Modeling diabetic sensory neuropathy in rats
    • Calcutt NA: Modeling diabetic sensory neuropathy in rats. Methods Mol Med 99:55-65, 2004
    • (2004) Methods Mol Med , vol.99 , pp. 55-65
    • Calcutt, N.A.1
  • 24
    • 12144279066 scopus 로고    scopus 로고
    • Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications
    • Obrosova IG, Pacher P, Szabo C, Zsengeller Z, Hirooka H, Stevens MJ, Yorek MA: Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications. Diabetes 54:234-242, 2005
    • (2005) Diabetes , vol.54 , pp. 234-242
    • Obrosova, I.G.1    Pacher, P.2    Szabo, C.3    Zsengeller, Z.4    Hirooka, H.5    Stevens, M.J.6    Yorek, M.A.7
  • 25
    • 2442482543 scopus 로고    scopus 로고
    • Experimental models of painful diabetic neuropathy
    • Calcutt NA: Experimental models of painful diabetic neuropathy. J Neurol Sci 220:137-139, 2004
    • (2004) J Neurol Sci , vol.220 , pp. 137-139
    • Calcutt, N.A.1
  • 26
    • 0036712066 scopus 로고    scopus 로고
    • Effects of the protein kinase C beta inhibitor LY333531 on neural and vascular function in rats with streptozotocin-induced diabetes
    • Cotter MA, Jack AM, Cameron NE: Effects of the protein kinase C beta inhibitor LY333531 on neural and vascular function in rats with streptozotocin-induced diabetes. Clin Sci (Lond) 103:311-321, 2002
    • (2002) Clin Sci (Lond) , vol.103 , pp. 311-321
    • Cotter, M.A.1    Jack, A.M.2    Cameron, N.E.3
  • 27
    • 0042669971 scopus 로고    scopus 로고
    • Looking to the future: Diabetic neuropathy and effects of rosuvastatin on neurovascular function in diabetes models
    • Cameron N, Cotter M, Inkster M, Nangle M: Looking to the future: diabetic neuropathy and effects of rosuvastatin on neurovascular function in diabetes models. Diabetes Res Clin Pract 61 (Suppl. 1):S35-S39, 2003
    • (2003) Diabetes Res Clin Pract , vol.61 , Issue.1 SUPPL.
    • Cameron, N.1    Cotter, M.2    Inkster, M.3    Nangle, M.4
  • 28
    • 3142761609 scopus 로고    scopus 로고
    • Update on the pathogenesis of diabetic neuropathy
    • Obrosova IG: Update on the pathogenesis of diabetic neuropathy. Curr Diab Rep 3:439-445, 2003
    • (2003) Curr Diab Rep , vol.3 , pp. 439-445
    • Obrosova, I.G.1
  • 29
    • 0035933419 scopus 로고    scopus 로고
    • Role of vanilloid VR1 receptor in thermal allodynia and hyperalgesia in diabetic mice
    • Kamei J, Zushida K, Morita K, Sasaki M, Tanaka S: Role of vanilloid VR1 receptor in thermal allodynia and hyperalgesia in diabetic mice. Eur J Pharmacol 422:83-86, 2001
    • (2001) Eur J Pharmacol , vol.422 , pp. 83-86
    • Kamei, J.1    Zushida, K.2    Morita, K.3    Sasaki, M.4    Tanaka, S.5
  • 30
    • 0141851856 scopus 로고    scopus 로고
    • Quercetin, a bioflavonoid, attenuates thermal hyperalgesia in a mouse model of diabetic neuropathic pain
    • Anjaneyulu M, Chopra K: Quercetin, a bioflavonoid, attenuates thermal hyperalgesia in a mouse model of diabetic neuropathic pain. Prog Neuropsychopharmacol Biol Psychiatry 27:1001-1005, 2003
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 1001-1005
    • Anjaneyulu, M.1    Chopra, K.2
  • 31
    • 17844367634 scopus 로고    scopus 로고
    • Low-dose poly(ADP-Ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy
    • Li F, Drel VR, Szabo C, Stevens MJ, Obrosova IG: Low-dose poly(ADP-Ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy. Diabetes 54:1514-1522, 2005
    • (2005) Diabetes , vol.54 , pp. 1514-1522
    • Li, F.1    Drel, V.R.2    Szabo, C.3    Stevens, M.J.4    Obrosova, I.G.5
  • 32
  • 33
    • 0041663746 scopus 로고    scopus 로고
    • Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice
    • Gustafsson H, Flood K, Berge OG, Brodin E, Olgart L, Stiller CO: Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice. Exp Neurol 182:427-434, 2003
    • (2003) Exp Neurol , vol.182 , pp. 427-434
    • Gustafsson, H.1    Flood, K.2    Berge, O.G.3    Brodin, E.4    Olgart, L.5    Stiller, C.O.6
  • 34
    • 28844459978 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury causes oxidative stress and apoptosis of Schwann cell in acute and chronic experimental diabetic neuropathy
    • Wang Y, Schmeichel AM, Iida H, Schmelzer JD, Low PA: Ischemia-reperfusion injury causes oxidative stress and apoptosis of Schwann cell in acute and chronic experimental diabetic neuropathy. Antioxid Redox Signal 7:1513-1520, 2005
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1513-1520
    • Wang, Y.1    Schmeichel, A.M.2    Iida, H.3    Schmelzer, J.D.4    Low, P.A.5
  • 37
    • 3042544529 scopus 로고    scopus 로고
    • Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice
    • Veres B, Radnai B, Gallyas F Jr, Varbiro G, Berente Z, Osz E, Sumegi B: Regulation of kinase cascades and transcription factors by a poly(ADP-ribose) polymerase-1 inhibitor, 4-hydroxyquinazoline, in lipopolysaccharide-induced inflammation in mice. J Pharmacol Exp Ther 310:247-255, 2004
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 247-255
    • Veres, B.1    Radnai, B.2    Gallyas Jr., F.3    Varbiro, G.4    Berente, Z.5    Osz, E.6    Sumegi, B.7
  • 38
    • 0037022627 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
    • Ha HC, Hester LD, Snyder SH: Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia. Proc Natl Acad Sci U S A 99:3270-3275, 2002
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3270-3275
    • Ha, H.C.1    Hester, L.D.2    Snyder, S.H.3
  • 39
    • 33644681565 scopus 로고    scopus 로고
    • Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: The relation is revisited
    • Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, Stevens MJ, Yorek MA: Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited. Diabetes 54:3435-3441, 2005
    • (2005) Diabetes , vol.54 , pp. 3435-3441
    • Obrosova, I.G.1    Drel, V.R.2    Pacher, P.3    Ilnytska, O.4    Wang, Z.Q.5    Stevens, M.J.6    Yorek, M.A.7
  • 41
    • 0032842640 scopus 로고    scopus 로고
    • Protein kinase C effects on nerve function, perfusion, Na(+), K(+)-ATPase activity and glutathione content in diabetic rats
    • Cameron NE, Cotter MA, Jack AM, Basso MD, Hohman TC: Protein kinase C effects on nerve function, perfusion, Na(+), K(+)-ATPase activity and glutathione content in diabetic rats. Diabetologia 42:1120-1130, 1999
    • (1999) Diabetologia , vol.42 , pp. 1120-1130
    • Cameron, N.E.1    Cotter, M.A.2    Jack, A.M.3    Basso, M.D.4    Hohman, T.C.5
  • 42
    • 0141884368 scopus 로고    scopus 로고
    • Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice
    • Yamagishi S, Uehara K, Otsuki S, Yagihashi S: Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice. J Neurochem 87:497-507, 2003
    • (2003) J Neurochem , vol.87 , pp. 497-507
    • Yamagishi, S.1    Uehara, K.2    Otsuki, S.3    Yagihashi, S.4
  • 43
    • 9444233894 scopus 로고    scopus 로고
    • Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice
    • Uehara K, Yamagishi S, Otsuki S, Chin S, Yagihashi S: Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice. Diabetes 53:3239-3247, 2004
    • (2004) Diabetes , vol.53 , pp. 3239-3247
    • Uehara, K.1    Yamagishi, S.2    Otsuki, S.3    Chin, S.4    Yagihashi, S.5
  • 45
    • 0037341207 scopus 로고    scopus 로고
    • Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: Role of oxidants and protein kinase-C activation
    • Abiko T, Abiko A, Clermont AC, Shoelson B, Horio N, Takahashi J, Adamis AP, King GL, Bursell SE: Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation. Diabetes 52:829-837, 2003
    • (2003) Diabetes , vol.52 , pp. 829-837
    • Abiko, T.1    Abiko, A.2    Clermont, A.C.3    Shoelson, B.4    Horio, N.5    Takahashi, J.6    Adamis, A.P.7    King, G.L.8    Bursell, S.E.9
  • 46
    • 21444439103 scopus 로고    scopus 로고
    • NAD(P)H oxidase activation: A potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome
    • Inoguchi T, Nawata H: NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome. Curr Drug Targets 6:495-501, 2005
    • (2005) Curr Drug Targets , vol.6 , pp. 495-501
    • Inoguchi, T.1    Nawata, H.2
  • 47
    • 0042822014 scopus 로고    scopus 로고
    • Sensory neurons with activated caspase-3 survive long-term experimental diabetes
    • Cheng C, Zochodne DW: Sensory neurons with activated caspase-3 survive long-term experimental diabetes. Diabetes 52:2363-2371, 2003
    • (2003) Diabetes , vol.52 , pp. 2363-2371
    • Cheng, C.1    Zochodne, D.W.2
  • 48
    • 9744252312 scopus 로고    scopus 로고
    • Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes
    • Burnand RC, Price SA, McElhaney M, Barker D, Tomlinson DR: Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes. Brain Res Mol Brain Res 132:235-240, 2004
    • (2004) Brain Res Mol Brain Res , vol.132 , pp. 235-240
    • Burnand, R.C.1    Price, S.A.2    McElhaney, M.3    Barker, D.4    Tomlinson, D.R.5
  • 49
    • 0037222391 scopus 로고    scopus 로고
    • Oxidative injury and apoptosis of dorsal root ganglion neurons in chronic experimental diabetic neuropathy
    • Schmeichel AM, Schmelzer JD, Low PA: Oxidative injury and apoptosis of dorsal root ganglion neurons in chronic experimental diabetic neuropathy. Diabetes 52:165-171, 2003
    • (2003) Diabetes , vol.52 , pp. 165-171
    • Schmeichel, A.M.1    Schmelzer, J.D.2    Low, P.A.3
  • 50
    • 33644680351 scopus 로고    scopus 로고
    • Apoptotic stress is counterbalanced by survival elements preventing programmed cell death of dorsal root ganglions in subacute type 1 diabetic BB/Wor rats
    • Kamiya H, Zhangm W, Sima AA: Apoptotic stress is counterbalanced by survival elements preventing programmed cell death of dorsal root ganglions in subacute type 1 diabetic BB/Wor rats. Diabetes 54:3288-3295, 2005
    • (2005) Diabetes , vol.54 , pp. 3288-3295
    • Kamiya, H.1    Zhangm, W.2    Sima, A.A.3
  • 51
    • 18944390248 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
    • Jagtap P, Szabo C: Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4:421-440, 2005
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 421-440
    • Jagtap, P.1    Szabo, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.