Functional consequences of α-synuclein tyrosine nitration: Diminished binding to lipid vesicles and increased fibril formation

Journal of Biological Chemistry

Volumn 279, Issue 46, 2004, Pages 47746-47753

  Hodara, Roberto ^a   Norris, Erin H ^a   Giasson, Benoit I ^a   Mishizen Eberz, Amanda J ^a   Lynch, David R ^a   Lee, Virginia M Y ^a   Ischiropoulos, Harry ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CHROMATOGRAPHIC ANALYSIS; CONFORMATIONS; DIMERS; ELECTRON MICROSCOPY; LIPIDS; OLIGOMERS; OXIDATION;

IMMUNOELECTRON MICROSCOPY; LIPID BINDING; PARKINSON DISEASE; PROTEOLYTIC DEGRADATION;

NITRATION;

ALPHA SYNUCLEIN; CALPAIN; DIMER; LIPOSOME; MONOMER; OLIGOMER; PROTEASOME; TYROSINE;

ALPHA HELIX; ARTICLE; CELL INCLUSION; CONTROLLED STUDY; FIBER; GEL FILTRATION CHROMATOGRAPHY; IMMUNOELECTRON MICROSCOPY; LIPID VESICLE; NITRATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FUNCTION;

ALPHA-SYNUCLEIN; ANIMALS; CALPAIN; HUMANS; INSULIN; LIPID METABOLISM; MICE; MOLECULAR CHAPERONES; NERVE TISSUE PROTEINS; NITRATES; OXYGEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, QUATERNARY; SYNUCLEINS; TYROSINE;

EID: 9144229591     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408906200     Document Type: Article

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