Poly(ADP-ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity

Circulation

Volumn 106, Issue 21, 2002, Pages 2680-2686

  Szabó, Csaba ^c,d   Zanchi, Anne ^a   Komjáti, Katalin ^c,d   Pacher, Pál ^d   Krolewski, Andrzej S ^a   Quist, William C ^b   LoGerfo, Frank W ^b   Horton, Edward S ^a   Veves, Aristidis ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

^d INOTEK CORPORATION   (United States)

Author keywords

Acetylcholine; Diabetes mellitus; Endothelium; Microcirculation

Indexed keywords

3 NITROTYROSINE; ACETYLCHOLINE; ADVANCED GLYCATION END PRODUCT RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE SYNTHASE;

ADULT; ARTICLE; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME ACTIVATION; FAMILY HISTORY; FEMALE; GENETIC POLYMORPHISM; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMPAIRED GLUCOSE TOLERANCE; MALE; MICROCIRCULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN BIOPSY; SKIN BLOOD FLOW; VASCULAR DISEASE; VASCULAR ENDOTHELIUM;

ACETYLCHOLINE; ANTIGENS, CD31; BIOPSY; CELL NUCLEUS; DIABETES MELLITUS, TYPE 2; DISEASE PROGRESSION; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FEMALE; FOREARM; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROCIRCULATION; MIDDLE AGED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; POLY(ADP-RIBOSE) POLYMERASES; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; RECEPTORS, IMMUNOLOGIC; REFERENCE VALUES; RISK ASSESSMENT; SKIN; STATISTICS; TYROSINE;

EID: 0037137287     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000038365.78031.9C     Document Type: Article

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