Induction of p100 processing by NF-κB-inducing kinase involves docking IκB kinase α (IKKα) to p100 and IKKα-mediated phosphorylation

Journal of Biological Chemistry

Volumn 279, Issue 29, 2004, Pages 30099-30105

  Xiao, Gutian ^a,b,c   Fong, Abraham ^a   Sun, Shao Cong ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GENES; GENETIC ENGINEERING; TUMORS;

PHOSPHORYLATION; TUMOR NECROSIS;

BIOCHEMISTRY;

AMINO ACID; GENE PRODUCT; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGENIC AGENT; NUCLEAR FACTOR KAPPA B INDUCING KINASE; NUCLEAR FACTOR KAPPA B2; PROTEASOME; PROTEIN P100; PROTEIN P52; SERINE; TUMOR NECROSIS FACTOR; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UBIQUITINATION;

BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; BINDING SITES; CELL LINE, TUMOR; GENETIC VECTORS; HUMANS; I-KAPPA B KINASE; NF-KAPPA B; NF-KAPPA B P52 SUBUNIT; PEPTIDE HYDROLASES; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SERINE; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 3142663912     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401428200     Document Type: Article

References (45)

1. Baldwin, A. S. (1996) Annu. Rev. Immunol. 14, 649-683
2. Ghosh, S., May, M. J., and Kopp, E. B. (1998) Annu. Rev. Immunol. 16, 225-260
3. Silverman, N., and Maniatis, T. (2001) Genes Dev. 15, 2321-2342
4. Ghosh, S., and Karin, M. (2002) Cell 109, S81-S96
5. Rayet, B., and Gelinas, C. (1999) Oncogene 18, 6938-6947
6. Karin, M., Cao, Y., Greten, F. R., and Li, Z. W. (2002) Nat. Rev. Cancer 2, 301-310
7. Sun, S.-C., and Xiao, G. (2003) Cancer Metastasis Rev. 22, 405-422
8. Siebenlist, U., Franzoso, G., and Brown, K. (1994) Annu. Rev. Cell Biol. 10, 405-455
9. Fan, C. M., and Maniatis, T. (1991) Nature 354, 395-398
10. Betts, J. C., and Nabel, G. J. (1996) Mol. Cell. Biol. 16, 6363-6371
11. Rice, N. R., MacKichan, M. L., and Israel, A. (1992) Cell 71, 243-253
12. Mercurio, F., DiDonato, J. A., Rosette, C., and Karin, M. (1993) Genes Dev. 7, 705-718
13. Karin, M., and Ben-Neriah, Y. (2000) Annu. Rev. Immunol. 18, 621-663
14. Lin, L., DeMartino, G. N., and Greene, W. C. (1998) Cell 92, 819-828
15. Xiao, G., Harhaj, E. W., and Sun, S.-C. (2001) Mol. Cell 7, 401-409
16. Senftleben, U., Cao, Y., Xiao, G., Greten, F. R., Krahn, G., Bonizzi, G., Chen, Y., Hu, Y., Fong, A., Sun, S. C., and Karin, M. (2001) Science 293, 1495-1499
17. Xiao, G., Civijic, M. E., Fong, A., Harhaj, E. W., Uhlik, M. T., Waterfield, M., and Sun, S.-C. (2001) The EMBO J. 20, 6805-6815
18. Dejardin, E., Droin, N. M., Delhase, M., Haas, E., Cao, Y., Makris, C., Li, Z. W., Karin, M., Ware, C. F., and Green, D. R. (2002) Immunity 17, 525-535
19. Claudio, E., Brown, K., Park, S., Wang, H., and Siebenlist, U. (2002) Nat. Immunol. 3, 958-965
20. Kayagaki, N., Yan, M., Seshasayee, D., Wang, H., Lee, W., French, D. M., Grewal, I. S., Cochran, A. G., Gordon, N. C., Yin, J., Starovasnik, M. A., and Dixit, V. M. (2002) Immunity 17, 515-524
21. Coope, H. J., Atkinson, P. G., Huhse, B., Belich, M., Janzen, J., Holman, M. J., Klaus, G. G., Johnston, L. H., and Ley, S. C. (2002) EMBO J. 21, 5375-5385
22. Caamano, J. H., Rizzo, C. A., Durham, S. K., Barton, D. S., Raventos-Suarez, C., Snapper, C. M., and Bravo, R. (1998) J. Exp. Med. 187, 185-196
23. Franzoso, G., Carlson, L., Poljak, L., Shores, E. W., Epstein, S., Leonardi, A., Grinberg, A., Tran, T., Scharton-Kersten, T., Anver, M., Love, P., Brown, K., and Siebenlist, U. (1998) J. Exp. Med. 187, 147-159
24. Sha, W. C., Liou, H. C., Tuomanen, E. I., and Baltimore, D. (1995) Cell 80, 321-330
25. Miyawaki, S., Nakamura, Y., Suzuka, H., Koba, M., Yasumizu, R., Ikehara, S., and Shibata, Y. (1994) Eur. J. Immunol. 24, 429-434
26. Thompson, J. S., Bixler, S. A., Qian, F., Vora, K., Scott, M. L., Cachero, T. G., Hession, C., Schneider, P., Sizing, I. D., Mullen, C., Strauch, K., Zafari, M., Benjamin, C. D., Tschopp, J., Browning, J. L., and Ambrose, C. (2001) Science 293, 2108-2111
27. Ishikawa, H., Carrasco, D., Claudio, E., Ryseck, R. P., and Bravo, R. (1997) J. Exp. Med. 186, 999-1014
28. Fracchiolla, N. S., Lombardi, L., Salina, M., Migliazza, A., Baldini, L., Berti, E., Cro, L., Polli, E., Maiolo, A. T., and Neri, A. (1993) Oncogene 8, 2839-2845
29. Zhang, J., Chang, C. C., Lombardi, L., and Dalla-Favera, R. (1994) Oncogene 9, 1931-1937
30. Thakur, S., Lin, H. C., Tseng, W. T., Kumar, S., Bravo, R., Foss, F., Gelinas, C., and Rabson, A. B. (1994) Oncogene 9, 2335-2344
31. Lanoix, J., Lacoste, J., Pepin, N., Rice, N., and Hiscott, J. (1994) Oncogene 9, 841-852
32. Cogswell, P. C., Guttridge, D. C., Funkhouser, W. K., and Baldwin, A. S., Jr. (2000) Oncogene 19, 1123-1131
33. Xiao, G., and Sun, S. C. (2000) J. Biol. Chem. 275, 21081-21085
34. Fong, A., and Sun, S. C. (2002) J. Biol. Chem. 277, 22111-22114
35. Beraud, C., Sun, S. C., Ganchi, P., Ballard, D. W., and Greene, W. C. (1994) Mol. Cell. Biol. 14, 1374-1382
36. Holbrook, N., Gulino, A., and Ruscetti, F. (1987) Virology 157, 211-219
37. Ling, L., Cao, Z., and Goeddel, D. V. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3792-3797
38. Luftig, M. A., Cahir-McFarland, E., Mosialos, G., and Kieff, E. (2001) J. Biol. Chem. 276, 14602-14606
39. De Togni, P., Goellner, J., Ruddle, N. H., Streeter, P. R., Fick, A., Mariathasan, S., Smith, S. C., Carlson, R., Shornick, L. P., Strauss-Schoenberger, J., Russell, J. H., Karr, R., and Chaplin, D. D. (1994) Science 264, 703-707
40. Futterer, A., Mink, K., Luz, A., Kosco-Vilbois, M. H., and Pfeffer, K. (1998) Immunity 9, 59-70
41. Schiemann, B., Gommerman, J. L., Vora, K., Cachero, T. G., Shulga-Morskaya, S., Dobles, M., Frew, E., and Scott, M. L. (2001) Science 293, 2111-2114
42. Liao, G., and Sun, S. C. (2003) Oncogene 22, 4868-4874
43. Cramer, P., Larson, C. J., Verdine, G. L., and Müller, C. W. (1997) EMBO J. 16, 7078-7090
44. Huxford, T., Huang, D. B., Malek, S., and Ghosh, G. (1998) Cell 95, 759-770
45. Jacobs, M. D., and Harrison, S. C. (1998) Cell 95, 749-758