-
1
-
-
4444376712
-
Signaling to NF-κB
-
Hayden MS and Ghosh S (2004) Signaling to NF-κB. Genes Dev. 18: 2195-2224
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
2
-
-
2342464085
-
The two NF-κB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G and Karin M (2004) The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25: 280-288
-
(2004)
Trends Immunol.
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
3
-
-
0033596121
-
Activators and target genes of Rel/NF-κB transcription factors
-
Pahl HL (1999) Activators and target genes of Rel/NF-κB transcription factors. Oncogene 18: 6853-6866
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Pahl, H.L.1
-
4
-
-
1642553460
-
To be, or not to be: NF-κB is the answer - Role of Rel/NF- κB in the regulation of apoptosis
-
Kucharczak J, Simmons MJ, Fan YJ and Gelinas C (2003) To be, or not to be: NF-κB is the answer - role of Rel/NF- κB in the regulation of apoptosis. Oncogene 22: 8961-8982
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
Simmons, M.J.2
Fan, Y.J.3
Gelinas, C.4
-
5
-
-
0346505340
-
The IKK NF-κB system: A treasure trove for drug development
-
Karin M, Yamamoto Y and Wang QM (2004) The IKK NF-κB system: A treasure trove for drug development. Nat. Rev. Drug Discov. 3: 17-26
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
6
-
-
14544269951
-
NF-κB in human disease: Current inhibitors and prospects for de novo structure based design of inhibitors
-
Pande V and Ramos MJ (2005) NF-κB in human disease: Current inhibitors and prospects for de novo structure based design of inhibitors. Curr. Med. Chem. 12: 357-374
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 357-374
-
-
Pande, V.1
Ramos, M.J.2
-
8
-
-
0442323562
-
NF-κB: Tumor promoter or suppressor?
-
Perkins ND (2004) NF-κB: Tumor promoter or suppressor? Trends Cell. Biol. 14: 64-69
-
(2004)
Trends Cell. Biol.
, vol.14
, pp. 64-69
-
-
Perkins, N.D.1
-
9
-
-
0031461976
-
Achieving transcriptional specificity with NF-κB
-
Perkins ND (1997) Achieving transcriptional specificity with NF-κB. Int. J. Biochem. Cell. Biol. 29: 1433-1448
-
(1997)
Int. J. Biochem. Cell. Biol.
, vol.29
, pp. 1433-1448
-
-
Perkins, N.D.1
-
10
-
-
0038771214
-
Modulation of NF-κB activity by exchange of dimers
-
Saccani S, Pantano S and Natoli G (2003) Modulation of NF-κB activity by exchange of dimers. Mol. Cell 11: 1563-1574
-
(2003)
Mol. Cell
, vol.11
, pp. 1563-1574
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
11
-
-
11844269840
-
Phosphorylation of NF-κB and IκB proteins: Implications in cancer and inflammation
-
Viatour P, Merville MP, Bours V and Chariot A (2005) Phosphorylation of NF-κB and IκB proteins: Implications in cancer and inflammation. Trends Biochem. Sci. 30: 43-52
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 43-52
-
-
Viatour, P.1
Merville, M.P.2
Bours, V.3
Chariot, A.4
-
12
-
-
7444254365
-
Oscillations in NF-κB signaling control the dynamics of gene expression
-
Nelson DE, Ihekwaba AE, Elliott M, Johnson JR, Gibney CA, Foreman BE, Nelson G, See V, Horton CA, Spiller DG, Edwards SW, McDowell HP, Unitt JF, Sullivan E, Grimley R, Benson N, Broomhead D, Kell DB and White MR (2004) Oscillations in NF-κB signaling control the dynamics of gene expression. Science 306: 704-708
-
(2004)
Science
, vol.306
, pp. 704-708
-
-
Nelson, D.E.1
Ihekwaba, A.E.2
Elliott, M.3
Johnson, J.R.4
Gibney, C.A.5
Foreman, B.E.6
Nelson, G.7
See, V.8
Horton, C.A.9
Spiller, D.G.10
Edwards, S.W.11
McDowell, H.P.12
Unitt, J.F.13
Sullivan, E.14
Grimley, R.15
Benson, N.16
Broomhead, D.17
Kell, D.B.18
White, M.R.19
-
13
-
-
10644248286
-
Post-translational modification of RelA(p65) NF-κB
-
Campbell KJ and Perkins ND (2004) Post-translational modification of RelA(p65) NF-κB. Biochem. Soc. Trans. 32: 1087-1089
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 1087-1089
-
-
Campbell, K.J.1
Perkins, N.D.2
-
14
-
-
0037044575
-
The IκB-NF-κB signaling module: Temporal control and selective gene activation
-
Hoffmann A, Levchenko A, Scott ML and Baltimore D (2002) The IκB-NF-κB signaling module: Temporal control and selective gene activation. Science 298: 1241-1245
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
15
-
-
0142105387
-
Genetic analysis of NF-κB/Rel transcription factors defines functional specificities
-
Hoffmann A, Leung TH and Baltimore D (2003) Genetic analysis of NF-κB/ Rel transcription factors defines functional specificities. EMBO J. 22: 5530-5539
-
(2003)
EMBO J.
, vol.22
, pp. 5530-5539
-
-
Hoffmann, A.1
Leung, T.H.2
Baltimore, D.3
-
16
-
-
9144275033
-
Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers
-
Bonizzi G, Bebien M, Otero DC, Johnson-Vroom KE, Cao Y, Vu D, Jegga AG, Aronow BJ, Ghosh G, Rickert RC and Karin M (2004) Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers. EMBO J. 23: 4202-4210
-
(2004)
EMBO J.
, vol.23
, pp. 4202-4210
-
-
Bonizzi, G.1
Bebien, M.2
Otero, D.C.3
Johnson-Vroom, K.E.4
Cao, Y.5
Vu, D.6
Jegga, A.G.7
Aronow, B.J.8
Ghosh, G.9
Rickert, R.C.10
Karin, M.11
-
17
-
-
6344264987
-
Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IκB kinase-induced proteolysis of NF-κB1 p105
-
Beinke S, Robinson MJ, Hugunin M and Ley SC (2004) Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IκB kinase-induced proteolysis of NF-κB1 p105. Mol. Cell. Biol. 24: 9658-9667
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9658-9667
-
-
Beinke, S.1
Robinson, M.J.2
Hugunin, M.3
Ley, S.C.4
-
18
-
-
0242298578
-
CK2 is a C-terminal IκB kinase responsible for NF-κB activation during the UV response
-
Kato T, Delhase M, Hoffmann A and Karin M (2003) CK2 is a C-terminal IκB kinase responsible for NF-κB activation during the UV response. Mol. Cell 12: 829-839
-
(2003)
Mol. Cell
, vol.12
, pp. 829-839
-
-
Kato, T.1
Delhase, M.2
Hoffmann, A.3
Karin, M.4
-
19
-
-
0037112514
-
Protein kinase CK2 promotes aberrant activation of nuclear factor-κB, transformed phenotype, and survival of breast cancer cells
-
Romieu-Mourez R, Landesman-Bollag E, Seldin DC and Sonenshein GE (2002) Protein kinase CK2 promotes aberrant activation of nuclear factor-κB, transformed phenotype, and survival of breast cancer cells. Cancer Res. 62: 6770-6778
-
(2002)
Cancer Res.
, vol.62
, pp. 6770-6778
-
-
Romieu-Mourez, R.1
Landesman-Bollag, E.2
Seldin, D.C.3
Sonenshein, G.E.4
-
20
-
-
0242664121
-
IκB kinase-independent IκBα degradation pathway: Functional NF-κB activity and implications for cancer therapy
-
Tergaonkar V, Bottero V, Ikawa M, Li QT and Verma IM (2003) IκB kinase-independent IκBα degradation pathway: Functional NF-κB activity and implications for cancer therapy. Mol. Cell. Biol. 23: 8070-8083
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8070-8083
-
-
Tergaonkar, V.1
Bottero, V.2
Ikawa, M.3
Li, Q.T.4
Verma, I.M.5
-
21
-
-
16044365828
-
Tyrosine phosphorylation of IκB-α activates NF-κB without proteolytic degradation of IκB-α
-
Imbert V, Rupec RA, Livolsi A, Pahl HL, Traenckner EB, Mueller-Dieckmann C, Farahifar D, Rossi B, Auberger P, Baeuerle PA and Peyron J (1996) Tyrosine phosphorylation of IκB-α activates NF-κB without proteolytic degradation of IκB-α. Cell 86: 787-798
-
(1996)
Cell
, vol.86
, pp. 787-798
-
-
Imbert, V.1
Rupec, R.A.2
Livolsi, A.3
Pahl, H.L.4
Traenckner, E.B.5
Mueller-Dieckmann, C.6
Farahifar, D.7
Rossi, B.8
Auberger, P.9
Baeuerle, P.A.10
Peyron, J.11
-
22
-
-
0034655179
-
Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of IκBα in NF-κB activation by an oxidative stress
-
Schoonbroodt S, Ferreira V, Best-Belpomme M, Boelaert JR, Legrand-Poels S, Korner M and Piette J (2000) Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of IκBα in NF-κB activation by an oxidative stress. J. Immunol. 164: 4292-4300
-
(2000)
J. Immunol.
, vol.164
, pp. 4292-4300
-
-
Schoonbroodt, S.1
Ferreira, V.2
Best-Belpomme, M.3
Boelaert, J.R.4
Legrand-Poels, S.5
Korner, M.6
Piette, J.7
-
23
-
-
0034708775
-
Pervanadate-induced nuclear factor-κB activation requires tyrosine phosphorylation and degradation of IκBα. Comparison with tumor necrosis factor-α
-
Mukhopadhyay A, Manna SK and Aggarwal BB (2000) Pervanadate-induced nuclear factor-κB activation requires tyrosine phosphorylation and degradation of IκBα. Comparison with tumor necrosis factor-α. J. Biol. Chem. 275: 8549-8555
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8549-8555
-
-
Mukhopadhyay, A.1
Manna, S.K.2
Aggarwal, B.B.3
-
24
-
-
0035911153
-
Activation of nuclear factor κB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IκBα
-
Bui NT, Livolsi A, Peyron JF and Prehn JH (2001) Activation of nuclear factor κB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IκBα. J. Cell. Biol. 152: 753-764
-
(2001)
J. Cell. Biol.
, vol.152
, pp. 753-764
-
-
Bui, N.T.1
Livolsi, A.2
Peyron, J.F.3
Prehn, J.H.4
-
25
-
-
0032491410
-
Tumor necrosis factor-α activation of nuclear transcription factor-κB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of IκBα
-
Abu-Amer Y, Ross FP, McHugh KP, Livolsi A, Peyron JF and Teitelbaum SL (1998) Tumor necrosis factor-α activation of nuclear transcription factor-κB in marrow macrophages is mediated by c-Src tyrosine phosphorylation of IκBα. J. Biol. Chem. 273: 29417-29423
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29417-29423
-
-
Abu-Amer, Y.1
Ross, F.P.2
McHugh, K.P.3
Livolsi, A.4
Peyron, J.F.5
Teitelbaum, S.L.6
-
26
-
-
0344305376
-
Sequential modification of NEMO/IKK gamma by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress
-
Huang TT, Wuerzbrger-Davis SM, Wu ZH and Miyamoto S (2003) Sequential modification of NEMO/IKK gamma by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress. Cell 115: 565-576
-
(2003)
Cell
, vol.115
, pp. 565-576
-
-
Huang, T.T.1
Wuerzbrger-Davis, S.M.2
Wu, Z.H.3
Miyamoto, S.4
-
27
-
-
2942716907
-
P53 induces NF-κB activation by an IκB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
-
Bohuslav J, Chen LF, Kwon H, Mu Y and Greene WC (2004) p53 induces NF-κB activation by an IκB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J. Biol. Chem. 279: 26115-26125
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26115-26125
-
-
Bohuslav, J.1
Chen, L.F.2
Kwon, H.3
Mu, Y.4
Greene, W.C.5
-
28
-
-
2442429408
-
Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import
-
Mattioli I, Sebald A, Bucher C, Charles RP, Nakano H, Doi T, Kracht M and Schmitz ML (2004) Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import. J. Immunol. 172: 6336-6344
-
(2004)
J. Immunol.
, vol.172
, pp. 6336-6344
-
-
Mattioli, I.1
Sebald, A.2
Bucher, C.3
Charles, R.P.4
Nakano, H.5
Doi, T.6
Kracht, M.7
Schmitz, M.L.8
-
29
-
-
27144459692
-
Phosphorylation of RelA/p65 on serine 536 defines an IκBα -independent NF-κB pathway
-
Sasaki CY, Barberi TJ, Ghosh P and Longo DL (2005) Phosphorylation of RelA/p65 on serine 536 defines an IκBα -independent NF-κB pathway. J. Biol. Chem. 280: 34538-34547
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 34538-34547
-
-
Sasaki, C.Y.1
Barberi, T.J.2
Ghosh, P.3
Longo, D.L.4
-
30
-
-
17844386319
-
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
-
Lawrence T, Bebien M, Liu GY, Nizet V and Karin M (2005) IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation. Nature 434: 1138-1143
-
(2005)
Nature
, vol.434
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
31
-
-
3142771914
-
Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response
-
Saccani S, Marazzi I, Beg AA and Natoli G (2004) Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response. J. Exp. Med. 200: 107-113
-
(2004)
J. Exp. Med.
, vol.200
, pp. 107-113
-
-
Saccani, S.1
Marazzi, I.2
Beg, A.A.3
Natoli, G.4
-
32
-
-
6344241039
-
SMRT derepression by the IκB kinase α: A prerequisite to NF-κB transcription and survival
-
Hoberg JE, Yeung F and Mayo MW (2004) SMRT derepression by the IκB kinase α: A prerequisite to NF-κB transcription and survival. Mol. Cell 16: 245-255
-
(2004)
Mol. Cell
, vol.16
, pp. 245-255
-
-
Hoberg, J.E.1
Yeung, F.2
Mayo, M.W.3
-
33
-
-
15944379896
-
Formation of an IKKα-dependent transcription complex is required for estrogen receptor-mediated gene activation
-
Park KJ, Krishnan V, O'Malley BW, Yamamoto Y and Gaynor RB (2005) Formation of an IKKα-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol. Cell 18: 71-82
-
(2005)
Mol. Cell
, vol.18
, pp. 71-82
-
-
Park, K.J.1
Krishnan, V.2
O'Malley, B.W.3
Yamamoto, Y.4
Gaynor, R.B.5
-
34
-
-
22544461297
-
Convergent actions of IκB kinase β and protein kinase Cδ modulate mRNA stability through phosphorylation of 14-3-3β complexed with tristetraprolin
-
Gringhuis SI, Garcia-Vallejo JJ, van Het Hof B and van Dijk W (2005) Convergent actions of IκB kinase β and protein kinase Cδ modulate mRNA stability through phosphorylation of 14-3-3β complexed with tristetraprolin. Mol. Cell. Biol. 25: 6454-6463
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6454-6463
-
-
Gringhuis, S.I.1
Garcia-Vallejo, J.J.2
van Het Hof, B.3
van Dijk, W.4
-
35
-
-
10644252695
-
IκB kinase β phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation
-
Lee S, Andrieu C, Saltel F, Destaing O, Auclair J, Pouchkine V, Michelon J, Salaun B, Kobayashi R, Jurdic P, Kieff ED and Sylla BS (2004) IκB kinase β phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation. Proc. Natl. Acad. Sci. USA 101: 17416-17421
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17416-17421
-
-
Lee, S.1
Andrieu, C.2
Saltel, F.3
Destaing, O.4
Auclair, J.5
Pouchkine, V.6
Michelon, J.7
Salaun, B.8
Kobayashi, R.9
Jurdic, P.10
Kieff, E.D.11
Sylla, B.S.12
-
36
-
-
11144357466
-
IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, Zou Y, Bao S, Hanada N, Saso H, Kobayashi R and Hung MC (2004) IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117: 225-237
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.1
Lee, D.F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.Y.6
Zou, Y.7
Bao, S.8
Hanada, N.9
Saso, H.10
Kobayashi, R.11
Hung, M.C.12
-
37
-
-
0346497823
-
NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK
-
Zhang JY, Green CL, Tao S and Khavari PA (2004) NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK. Genes Dev. 18: 17-22
-
(2004)
Genes Dev.
, vol.18
, pp. 17-22
-
-
Zhang, J.Y.1
Green, C.L.2
Tao, S.3
Khavari, P.A.4
-
38
-
-
0035809983
-
IKK α controls formation of the epidermis independently of NF-κB
-
Hu YL, Baud V, Oga T, Kim KII, Yoshida K and Karin M (2001) IKK α controls formation of the epidermis independently of NF-κB. Nature 410: 710-714
-
(2001)
Nature
, vol.410
, pp. 710-714
-
-
Hu, Y.L.1
Baud, V.2
Oga, T.3
Kim, K.I.I.4
Yoshida, K.5
Karin, M.6
-
39
-
-
0442309823
-
A dual role for IKK α in tooth development
-
Ohazama A, Hu Y, Schmidt-Ullrich R, Cao Y, Scheidereit C, Karin M and Sharpe PT (2004) A dual role for IKK α in tooth development. Dev. Cell 6: 219-227
-
(2004)
Dev. Cell
, vol.6
, pp. 219-227
-
-
Ohazama, A.1
Hu, Y.2
Schmidt-Ullrich, R.3
Cao, Y.4
Scheidereit, C.5
Karin, M.6
Sharpe, P.T.7
-
40
-
-
17144420466
-
Activity of hypoxia-inducible factor 2α is regulated by association with the NF-κB essential modulator
-
Bracken CP, Whitelaw ML and Peet DJ (2005) Activity of hypoxia-inducible factor 2α is regulated by association with the NF-κB essential modulator. J. Biol. Chem. 280: 14240-14251
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14240-14251
-
-
Bracken, C.P.1
Whitelaw, M.L.2
Peet, D.J.3
-
41
-
-
0035379555
-
Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
-
Madrid LV, Mayo MW, Reuther JY and Baldwin AS (2001) Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276: 18934-18940
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18934-18940
-
-
Madrid, L.V.1
Mayo, M.W.2
Reuther, J.Y.3
Baldwin, A.S.4
-
42
-
-
27144477415
-
Activated AKT regulates NF-κB activation, p53 inhibition and cell survival in HTLV-1-transformed cells
-
Jeong SJ, Pise-Masison CA, Radonovich MF, Park HU and Brady JN (2005) Activated AKT regulates NF-κB activation, p53 inhibition and cell survival in HTLV-1-transformed cells. Oncogene 24: 6719-6728
-
(2005)
Oncogene
, vol.24
, pp. 6719-6728
-
-
Jeong, S.J.1
Pise-Masison, C.A.2
Radonovich, M.F.3
Park, H.U.4
Brady, J.N.5
-
43
-
-
0037064052
-
IKKβ and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-κB activation in both primary and intestinal epithelial cell lines
-
Haller D, Russo MP, Sartor RB and Jobin C (2002) IKKβ and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-κB activation in both primary and intestinal epithelial cell lines. J. Biol. Chem. 277: 38168-38178
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38168-38178
-
-
Haller, D.1
Russo, M.P.2
Sartor, R.B.3
Jobin, C.4
-
44
-
-
0032488837
-
P38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor κB p65 transactivation mediated by tumor necrosis factor
-
Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W and Haegeman G (1998) p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor κB p65 transactivation mediated by tumor necrosis factor. J. Biol. Chem. 273: 3285-3290
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3285-3290
-
-
Vanden Berghe, W.1
Plaisance, S.2
Boone, E.3
De Bosscher, K.4
Schmitz, M.L.5
Fiers, W.6
Haegeman, G.7
-
45
-
-
0036143654
-
P38-dependent marking of inflammatory genes for increased NF-κB recruitment
-
Saccani S, Pantano S and Natoli G (2002) p38-dependent marking of inflammatory genes for increased NF-κB recruitment. Nat. Immunol. 3: 69-75
-
(2002)
Nat. Immunol.
, vol.3
, pp. 69-75
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
46
-
-
0038182524
-
MSK2 and MSK1 mediate the mitogen-and stress-induced phosphorylation of histone H3 and HMG-14
-
Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, Mahadevan LC and Arthur JS (2003) MSK2 and MSK1 mediate the mitogen-and stress-induced phosphorylation of histone H3 and HMG-14. EMBO J. 22: 2788-2797
-
(2003)
EMBO J.
, vol.22
, pp. 2788-2797
-
-
Soloaga, A.1
Thomson, S.2
Wiggin, G.R.3
Rampersaud, N.4
Dyson, M.H.5
Hazzalin, C.A.6
Mahadevan, L.C.7
Arthur, J.S.8
-
47
-
-
5644264889
-
The nuclear factor κB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation
-
Hanson JL, Hawke NA, Kashatus D and Baldwin AS (2004) The nuclear factor κB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation. Cancer Res. 64: 7248-7255
-
(2004)
Cancer Res.
, vol.64
, pp. 7248-7255
-
-
Hanson, J.L.1
Hawke, N.A.2
Kashatus, D.3
Baldwin, A.S.4
-
48
-
-
0037711555
-
Mutations within a conserved protein kinase A recognition sequence confer temperature-sensitive and partially defective activities onto mouse c-Rel
-
Gapuzan M-E, Pitoc GA and Gilmore TD (2003) Mutations within a conserved protein kinase A recognition sequence confer temperature-sensitive and partially defective activities onto mouse c-Rel. Biochem. Biophys. Res. Commun. 307: 92-99
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.307
, pp. 92-99
-
-
Gapuzan, M.-E.1
Pitoc, G.A.2
Gilmore, T.D.3
-
49
-
-
0347955360
-
Regulation of NF-κB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
-
Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, Rottapel R, Yamaoka S and Lu KP (2003) Regulation of NF-κB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol. Cell 12: 1413-1426
-
(2003)
Mol. Cell
, vol.12
, pp. 1413-1426
-
-
Ryo, A.1
Suizu, F.2
Yoshida, Y.3
Perrem, K.4
Liou, Y.C.5
Wulf, G.6
Rottapel, R.7
Yamaoka, S.8
Lu, K.P.9
-
50
-
-
2942702021
-
Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-κB activation by protein phosphatase 4-mediated NF-κB p65 Thr dephosphorylation
-
Yeh PY, Yeh KH, Chuang SE, Song YC and Cheng AL (2004) Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-κB activation by protein phosphatase 4-mediated NF-κB p65 Thr dephosphorylation. J. Biol. Chem. 279: 26143-26148
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26143-26148
-
-
Yeh, P.Y.1
Yeh, K.H.2
Chuang, S.E.3
Song, Y.C.4
Cheng, A.L.5
-
51
-
-
17144422434
-
Regulation of NF-κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
-
Rocha S, Garrett MD, Campbell KJ, Schumm K and Perkins ND (2005) Regulation of NF-κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor. EMBO J. 24: 1157-1169
-
(2005)
EMBO J.
, vol.24
, pp. 1157-1169
-
-
Rocha, S.1
Garrett, M.D.2
Campbell, K.J.3
Schumm, K.4
Perkins, N.D.5
-
52
-
-
0041324898
-
The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression
-
De Bosscher K, Vanden Berghe W and Haegeman G (2003) The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression. Endocr. Rev. 24: 488-522
-
(2003)
Endocr. Rev.
, vol.24
, pp. 488-522
-
-
De Bosscher, K.1
Vanden Berghe, W.2
Haegeman, G.3
-
53
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65) NF-κB
-
Campbell KJ, Rocha S and Perkins ND (2004) Active repression of antiapoptotic gene expression by RelA(p65) NF-κB. Mol. Cell 13: 853-865
-
(2004)
Mol. Cell
, vol.13
, pp. 853-865
-
-
Campbell, K.J.1
Rocha, S.2
Perkins, N.D.3
-
54
-
-
20144365514
-
Nuclear factor-κB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-κB-dependent transcription in cancer cells
-
Ho WC, Dickson KM and Barker PA (2005) Nuclear factor-κB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-κB-dependent transcription in cancer cells. Cancer Res. 65: 4273-4281
-
(2005)
Cancer Res.
, vol.65
, pp. 4273-4281
-
-
Ho, W.C.1
Dickson, K.M.2
Barker, P.A.3
-
56
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA and Mayo MW (2004) Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23: 2369-2380
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
57
-
-
24344468250
-
NF-κB RelA phosphorylation regulates RelA acetylation
-
Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L and Greene WC (2005) NF-κB RelA phosphorylation regulates RelA acetylation. Mol. Cell. Biol. 25: 7966-7975
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7966-7975
-
-
Chen, L.F.1
Williams, S.A.2
Mu, Y.3
Nakano, H.4
Duerr, J.M.5
Buckbinder, L.6
Greene, W.C.7
-
58
-
-
18244379306
-
Interactions of NF-κB with chromatin: The art of being at the right place at the right time
-
Natoli G, Saccani S, Bosisio D and Marazzi I (2005) Interactions of NF-κB with chromatin: The art of being at the right place at the right time. Nat. Immunol. 6: 439-445
-
(2005)
Nat. Immunol.
, vol.6
, pp. 439-445
-
-
Natoli, G.1
Saccani, S.2
Bosisio, D.3
Marazzi, I.4
-
60
-
-
0035929147
-
Nucleosome sliding via TBP DNA binding in vivo
-
Lomvardas S and Thanos D (2001) Nucleosome sliding via TBP DNA binding in vivo. Cell 106: 685-696
-
(2001)
Cell
, vol.106
, pp. 685-696
-
-
Lomvardas, S.1
Thanos, D.2
-
61
-
-
3042834382
-
The IκB kinase complex and NF-κB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1
-
Krappmann D, Wegener E, Sunami Y, Esen M, Thiel A, Mordmuller B and Scheidereit C (2004) The IκB kinase complex and NF-κB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1. Mol. Cell. Biol. 24: 6488-6500
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6488-6500
-
-
Krappmann, D.1
Wegener, E.2
Sunami, Y.3
Esen, M.4
Thiel, A.5
Mordmuller, B.6
Scheidereit, C.7
-
62
-
-
4644252538
-
One nucleotide in a κB site can determine cofactor specificity for NF-κB dimers
-
Leung TH, Hoffmann A and Baltimore D (2004) One nucleotide in a κB site can determine cofactor specificity for NF-κB dimers. Cell 118: 453-464
-
(2004)
Cell
, vol.118
, pp. 453-464
-
-
Leung, T.H.1
Hoffmann, A.2
Baltimore, D.3
-
63
-
-
0141780826
-
NF-κB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism
-
Sitcheran R, Cogswell PC and Baldwin Jr AS (2003) NF-κB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes Dev. 17: 2368-2373
-
(2003)
Genes Dev.
, vol.17
, pp. 2368-2373
-
-
Sitcheran, R.1
Cogswell, P.C.2
Baldwin Jr., A.S.3
-
64
-
-
0037474269
-
NF-κB and IκBα are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-κB
-
Cogswell PC, Kashatus DF, Keifer JA, Guttridge DC, Reuther JY, Bristow C, Roy S, Nicholson DW and Baldwin Jr AS (2003) NF-κB and IκBα are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-κB. J. Biol. Chem. 278: 2963-2968
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2963-2968
-
-
Cogswell, P.C.1
Kashatus, D.F.2
Keifer, J.A.3
Guttridge, D.C.4
Reuther, J.Y.5
Bristow, C.6
Roy, S.7
Nicholson, D.W.8
Baldwin Jr., A.S.9
-
65
-
-
21744444276
-
Nucleolar sequestration of RelA (p65) regulates NF-κB-driven transcription and apoptosis
-
Stark LA and Dunlop MG (2005) Nucleolar sequestration of RelA (p65) regulates NF-κB-driven transcription and apoptosis. Mol. Cell. Biol. 25: 5985-6004
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5985-6004
-
-
Stark, L.A.1
Dunlop, M.G.2
-
66
-
-
26444605834
-
IKK/NF-κB signaling: Balancing life and death - A new approach to cancer therapy
-
Luo JL, Kamata H and Karin M (2005) IKK/NF-κB signaling: Balancing life and death - a new approach to cancer therapy. J. Clin. Invest. 115: 2625-2632
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2625-2632
-
-
Luo, J.L.1
Kamata, H.2
Karin, M.3
-
67
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF and Karin M (2004) IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118: 285-296
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
68
-
-
0036599406
-
P53 stabilization is decreased upon NFκB activation: A role for NFκB in acquisition of resistance to chemotherapy
-
Tergaonkar V, Pando M, Vafa O, Wahl G and Verma I (2002) p53 stabilization is decreased upon NFκB activation: A role for NFκB in acquisition of resistance to chemotherapy. Cancer Cell 1: 493-503
-
(2002)
Cancer Cell
, vol.1
, pp. 493-503
-
-
Tergaonkar, V.1
Pando, M.2
Vafa, O.3
Wahl, G.4
Verma, I.5
-
69
-
-
0034689773
-
Role of NF-κB in p53-mediated programmed cell death
-
Ryan KM, Ernst MK, Rice NR and Vousden KH (2000) Role of NF-κB in p53-mediated programmed cell death. Nature 404: 892-897
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
70
-
-
0038409927
-
P53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-κB subunit with histone deacetylase 1
-
Rocha S, Martin AM, Meek DW and Perkins ND (2003) p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-κB subunit with histone deacetylase 1. Mol. Cell. Biol. 23: 4713-4727
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4713-4727
-
-
Rocha, S.1
Martin, A.M.2
Meek, D.W.3
Perkins, N.D.4
-
71
-
-
0043172452
-
P53- and Mdm2-independent repression of NF-κB transactivation by the ARF tumor suppressor
-
Rocha S, Campbell KJ and Perkins ND (2003) p53- and Mdm2-independent repression of NF-κB transactivation by the ARF tumor suppressor. Mol. Cell 12: 15-25
-
(2003)
Mol. Cell
, vol.12
, pp. 15-25
-
-
Rocha, S.1
Campbell, K.J.2
Perkins, N.D.3
-
72
-
-
0037061742
-
Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-κB have a malignantly transformed phenotype
-
Gapuzan M-ER, Yufit PV and Gilmore TD (2002) Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-κB have a malignantly transformed phenotype. Oncogene 21: 2484-2492
-
(2002)
Oncogene
, vol.21
, pp. 2484-2492
-
-
Gapuzan, M.-E.R.1
Yufit, P.V.2
Gilmore, T.D.3
-
73
-
-
26944478633
-
Immortalized fibroblasts from NF-κB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor α after transformation by v-Ras
-
Gapuzan M-E, Schmah O, Pollock AD, Hoffmann A and Gilmore TD (2005) Immortalized fibroblasts from NF-κB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor α after transformation by v-Ras. Oncogene 24: 6574-6583
-
(2005)
Oncogene
, vol.24
, pp. 6574-6583
-
-
Gapuzan, M.-E.1
Schmah, O.2
Pollock, A.D.3
Hoffmann, A.4
Gilmore, T.D.5
-
74
-
-
3042780178
-
Loss of nuclear factor-κB is tumor promoting but does not substitute for loss of p53
-
Ryan KM, O'Prey J and Vousden KH (2004) Loss of nuclear factor-κB is tumor promoting but does not substitute for loss of p53. Cancer Res. 64: 4415-4418
-
(2004)
Cancer Res.
, vol.64
, pp. 4415-4418
-
-
Ryan, K.M.1
O'Prey, J.2
Vousden, K.H.3
-
75
-
-
19744371746
-
Impaired inhibition of NF-κB activity by melanoma-associated p16INK4a mutations
-
Becker TM, Rizos H, de la Pena A, Leclercq IA, Woodruff S, Kefford RF and Mann GJ (2005) Impaired inhibition of NF-κB activity by melanoma-associated p16INK4a mutations. Biochem. Biophys. Res. Commun. 332: 873-879
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, pp. 873-879
-
-
Becker, T.M.1
Rizos, H.2
de la Pena, A.3
Leclercq, I.A.4
Woodruff, S.5
Kefford, R.F.6
Mann, G.J.7
-
76
-
-
3843099360
-
Inverse correlation between p16INK4A expression and NF-κB activation in melanoma progression
-
Ghiorzo P, Mantelli M, Gargiulo S, Gramigni C, Pastorino L, Banelli B, Villaggio B, Coccia MC, Sementa AR, Garre C and Bianchi-Scarra G (2004) Inverse correlation between p16INK4A expression and NF-κB activation in melanoma progression. Hum. Pathol. 35: 1029-1037
-
(2004)
Hum. Pathol.
, vol.35
, pp. 1029-1037
-
-
Ghiorzo, P.1
Mantelli, M.2
Gargiulo, S.3
Gramigni, C.4
Pastorino, L.5
Banelli, B.6
Villaggio, B.7
Coccia, M.C.8
Sementa, A.R.9
Garre, C.10
Bianchi-Scarra, G.11
-
77
-
-
1642586297
-
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
-
Garkavtsev I, Kozin SV, Chernova O, Xu L, Winkler F, Brown E, Barnett GH and Jain RK (2004) The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature 428: 328-332
-
(2004)
Nature
, vol.428
, pp. 328-332
-
-
Garkavtsev, I.1
Kozin, S.V.2
Chernova, O.3
Xu, L.4
Winkler, F.5
Brown, E.6
Barnett, G.H.7
Jain, R.K.8
-
78
-
-
0037192829
-
PTEN blocks tumor necrosis factor-induced NF-κB-dependent transcription by inhibiting the transactivation potential of the p65 subunit
-
Mayo MW, Madrid LV, Westerheide SD, Jones DR, Yuan XJ, Baldwin Jr AS and Whang YE (2002) PTEN blocks tumor necrosis factor-induced NF-κB-dependent transcription by inhibiting the transactivation potential of the p65 subunit. J. Biol. Chem. 277: 11116-11125
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11116-11125
-
-
Mayo, M.W.1
Madrid, L.V.2
Westerheide, S.D.3
Jones, D.R.4
Yuan, X.J.5
Baldwin Jr., A.S.6
Whang, Y.E.7
-
79
-
-
0035139943
-
Hostile takeovers: Viral appropriation of the NF-κB pathway
-
Hiscott J, Kwon H and Genin P (2001) Hostile takeovers: Viral appropriation of the NF-κB pathway. J. Clin. Invest. 107: 143-151
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 143-151
-
-
Hiscott, J.1
Kwon, H.2
Genin, P.3
-
80
-
-
0036781671
-
β-catenin interacts with and inhibits NF-κB in human colon and breast cancer
-
Deng JO, Miller SA, Wang HY, Xia WY, Wen Y, Zhou BHP, Li Y, Lin SY and Hung MC (2002) β-catenin interacts with and inhibits NF-κB in human colon and breast cancer. Cancer Cell 2: 323-334
-
(2002)
Cancer Cell
, vol.2
, pp. 323-334
-
-
Deng, J.O.1
Miller, S.A.2
Wang, H.Y.3
Xia, W.Y.4
Wen, Y.5
Zhou, B.H.P.6
Li, Y.7
Lin, S.Y.8
Hung, M.C.9
-
81
-
-
1542618320
-
Crossregulation of NF-κB by the APC/GSK-3β/β-catenin pathway
-
Deng J, Xia W, Miller SA, Wen Y, Wang HY and Hung MC (2004) Crossregulation of NF-κB by the APC/GSK-3β/β-catenin pathway. Mol. Carcinog. 39: 139-146
-
(2004)
Mol. Carcinog.
, vol.39
, pp. 139-146
-
-
Deng, J.1
Xia, W.2
Miller, S.A.3
Wen, Y.4
Wang, H.Y.5
Hung, M.C.6
-
82
-
-
17244378084
-
Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes
-
Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG and Baek SH (2005) Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes. Nature 434: 921-926
-
(2005)
Nature
, vol.434
, pp. 921-926
-
-
Kim, J.H.1
Kim, B.2
Cai, L.3
Choi, H.J.4
Ohgi, K.A.5
Tran, C.6
Chen, C.7
Chung, C.H.8
Huber, O.9
Rose, D.W.10
Sawyers, C.L.11
Rosenfeld, M.G.12
Baek, S.H.13
-
83
-
-
0036782443
-
A novel protein overexpressed in hepatoma accelerates export of NF-κB from the nucleus and inhibits p53-dependent apoptosis
-
Higashitsuji H, Nagao T, Nonoguchi K, Fujii S, Itoh K and Fujita J (2002) A novel protein overexpressed in hepatoma accelerates export of NF-κB from the nucleus and inhibits p53-dependent apoptosis. Cancer Cell 2: 335-346
-
(2002)
Cancer Cell
, vol.2
, pp. 335-346
-
-
Higashitsuji, H.1
Nagao, T.2
Nonoguchi, K.3
Fujii, S.4
Itoh, K.5
Fujita, J.6
-
85
-
-
17144384376
-
NF-κB and JNK: An intricate affair
-
Bubici C, Papa S, Pham CG, Zazzeroni F and Franzoso G (2004) NF-κB and JNK: An intricate affair. Cell Cycle 3: 1524-1529
-
(2004)
Cell Cycle
, vol.3
, pp. 1524-1529
-
-
Bubici, C.1
Papa, S.2
Pham, C.G.3
Zazzeroni, F.4
Franzoso, G.5
-
86
-
-
14844327760
-
Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata H, Honda S, Maeda S, Chang L, Hirata H and Karin M (2005) Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120: 649-661
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
87
-
-
0037421484
-
NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
-
Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ, Marinkovich MP, Tao SY, Lin Q, Kubo Y and Khavari PA (2003) NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 421: 639-643
-
(2003)
Nature
, vol.421
, pp. 639-643
-
-
Dajee, M.1
Lazarov, M.2
Zhang, J.Y.3
Cai, T.4
Green, C.L.5
Russell, A.J.6
Marinkovich, M.P.7
Tao, S.Y.8
Lin, Q.9
Kubo, Y.10
Khavari, P.A.11
-
88
-
-
0033565763
-
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling
-
van Hogerlinden M, Rozell BL, Ährlund-Richter L and Toftgård R (1999) Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling. Cancer Res. 59: 3299-3303
-
(1999)
Cancer Res.
, vol.59
, pp. 3299-3303
-
-
van Hogerlinden, M.1
Rozell, B.L.2
Ährlund-Richter, L.3
Toftgård, R.4
-
89
-
-
1842788118
-
Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition
-
Lind MH, Rozell B, Wallin RP, van Hogerlinden M, Ljunggren HG, Toftgård R and Sur I (2004) Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition. Proc. Natl. Acad. Sci. USA 101: 4972-4977
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4972-4977
-
-
Lind, M.H.1
Rozell, B.2
Wallin, R.P.3
van Hogerlinden, M.4
Ljunggren, H.G.5
Toftgård, R.6
Sur, I.7
-
90
-
-
13944253943
-
CDK4 regulation by TNFR1 and JNK is required for NF-κB-mediated epidermal growth control
-
Zhang JY, Tao S, Kimmel R and Khavari PA (2005) CDK4 regulation by TNFR1 and JNK is required for NF-κB-mediated epidermal growth control. J. Cell. Biol. 168: 561-566
-
(2005)
J. Cell. Biol.
, vol.168
, pp. 561-566
-
-
Zhang, J.Y.1
Tao, S.2
Kimmel, R.3
Khavari, P.A.4
-
91
-
-
0037417129
-
Divergent gene regulation and growth effects by NF-κB in epithelial and mesenchymal cells of human skin
-
Hinata K, Gervin AM, Zhang YJ and Khavari PA (2003) Divergent gene regulation and growth effects by NF-κB in epithelial and mesenchymal cells of human skin. Oncogene 22: 1955-1964
-
(2003)
Oncogene
, vol.22
, pp. 1955-1964
-
-
Hinata, K.1
Gervin, A.M.2
Zhang, Y.J.3
Khavari, P.A.4
-
92
-
-
21244472975
-
IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
Maeda S, Kamata H, Luo JL, Leffert H and Karin M (2005) IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121: 977-990
-
(2005)
Cell
, vol.121
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.L.3
Leffert, H.4
Karin, M.5
-
94
-
-
6344269169
-
A role for NF-κB subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock
-
Gadjeva M, Tomczak MF, Zhang M, Wang YY, Dull K, Rogers AB, Erdman SE, Fox JG, Carroll M and Horwitz BH (2004) A role for NF-κB subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock. J. Immunol. 173: 5786-5793
-
(2004)
J. Immunol.
, vol.173
, pp. 5786-5793
-
-
Gadjeva, M.1
Tomczak, M.F.2
Zhang, M.3
Wang, Y.Y.4
Dull, K.5
Rogers, A.B.6
Erdman, S.E.7
Fox, J.G.8
Carroll, M.9
Horwitz, B.H.10
-
95
-
-
0035861314
-
IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development
-
Cao YX, Bonizzi G, Seagroves TN, Greten FR, Johnson R, Schmidt EV and Karin M (2001) IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development. Cell 107: 763-775
-
(2001)
Cell
, vol.107
, pp. 763-775
-
-
Cao, Y.X.1
Bonizzi, G.2
Seagroves, T.N.3
Greten, F.R.4
Johnson, R.5
Schmidt, E.V.6
Karin, M.7
-
96
-
-
0037142027
-
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
-
Pasparakis M, Courtois G, Hafner M, Schmidt-Supprian M, Nenci A, Toksoy A, Krampert M, Goebeler M, Gillitzer R, Israel A, Krieg T, Rajewsky K and Haase I (2002) TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 417: 861-866
-
(2002)
Nature
, vol.417
, pp. 861-866
-
-
Pasparakis, M.1
Courtois, G.2
Hafner, M.3
Schmidt-Supprian, M.4
Nenci, A.5
Toksoy, A.6
Krampert, M.7
Goebeler, M.8
Gillitzer, R.9
Israel, A.10
Krieg, T.11
Rajewsky, K.12
Haase, I.13
-
97
-
-
20144388823
-
Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury
-
Luedde T, Assmus U, Wustefeld T, Meyer zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M and Trautwein C (2005) Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/ reperfusion injury. J. Clin. Invest. 115: 849-859
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 849-859
-
-
Luedde, T.1
Assmus, U.2
Wustefeld, T.3
Meyer zu Vilsendorf, A.4
Roskams, T.5
Schmidt-Supprian, M.6
Rajewsky, K.7
Brenner, D.A.8
Manns, M.P.9
Pasparakis, M.10
Trautwein, C.11
-
98
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
-
Wang CY, Cusack Jr JC, Liu R and Baldwin Jr AS (1999) Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB. Nat Med 5: 412-417
-
(1999)
Nat Med
, vol.5
, pp. 412-417
-
-
Wang, C.Y.1
Cusack Jr., J.C.2
Liu, R.3
Baldwin Jr., A.S.4
-
99
-
-
31044445246
-
Inhibition of transcription factor NF-κB signaling proteins IKKβ and p65 through specific cysteine residues by epoxyquinone A monomer: Correlation with its anti-cancer cell growth activity
-
in press
-
Liang M-C, Bardhan S, Porco Jr JA and Gilmore TD (2006) Inhibition of transcription factor NF-κB signaling proteins IKKβ and p65 through specific cysteine residues by epoxyquinone A monomer: Correlation with its anti-cancer cell growth activity. Biochem. Pharmacol., in press
-
(2006)
Biochem. Pharmacol.
-
-
Liang, M.-C.1
Bardhan, S.2
Porco Jr., J.A.3
Gilmore, T.D.4
-
100
-
-
3543018495
-
Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer
-
Curry III EA, Murry DJ, Yoder C, Fife K, Armstrong V, Nakshatri H, O'Connell M and Sweeney CJ (2004) Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer. Invest. New Drugs 22: 299-305
-
(2004)
Invest. New Drugs
, vol.22
, pp. 299-305
-
-
Curry III, E.A.1
Murry, D.J.2
Yoder, C.3
Fife, K.4
Armstrong, V.5
Nakshatri, H.6
O'Connell, M.7
Sweeney, C.J.8
|