-
1
-
-
0032530455
-
Tumor necrosis factor receptor-associated factors (TRAFs) - A family of adapter proteins that regulates life and death
-
Arch, R. H., R. W. Gedrich, and C. B. Thompson. 1998. Tumor necrosis factor receptor-associated factors (TRAFs) - a family of adapter proteins that regulates life and death. Genes Dev. 12:2821-2830.
-
(1998)
Genes Dev.
, vol.12
, pp. 2821-2830
-
-
Arch, R.H.1
Gedrich, R.W.2
Thompson, C.B.3
-
2
-
-
0033563101
-
Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino terminal effector domain
-
Baud, V., Z.-G. Liu, B. Bennett, N. Suzuki, Y. Xia, and M. Karin. 1999. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino terminal effector domain. Genes Dev. 13:1297-1308.
-
(1999)
Genes Dev.
, vol.13
, pp. 1297-1308
-
-
Baud, V.1
Liu, Z.-G.2
Bennett, B.3
Suzuki, N.4
Xia, Y.5
Karin, M.6
-
3
-
-
0024503589
-
Prolonged activation of c-jun and collagenase genes by tumor necrosis factor-alpha
-
Brenner, D. A., M. O'Hara, P. Angel, M. Chojkier, and M. Karin. 1989. Prolonged activation of c-jun and collagenase genes by tumor necrosis factor-alpha. Nature 337:661-663.
-
(1989)
Nature
, vol.337
, pp. 661-663
-
-
Brenner, D.A.1
O'Hara, M.2
Angel, P.3
Chojkier, M.4
Karin, M.5
-
4
-
-
0032544309
-
Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx
-
Chang, H. Y., H. Nishitoh, X. Yang, H. Ichijo, and D. Baltimore. 1998. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 281:1860-1863.
-
(1998)
Science
, vol.281
, pp. 1860-1863
-
-
Chang, H.Y.1
Nishitoh, H.2
Yang, X.3
Ichijo, H.4
Baltimore, D.5
-
5
-
-
0029090167
-
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
-
Goossens, V., J. Grooten, K. De Vos, and W. Fiers. 1995. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. Proc. Natl. Acad. Sci. USA 92:8115-8119.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8115-8119
-
-
Goossens, V.1
Grooten, J.2
De Vos, K.3
Fiers, W.4
-
6
-
-
0032504189
-
Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor - α signal transduction
-
Gotoh, Y., and J. A. Cooper. 1998. Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor - α signal transduction. J. Biol. Chem. 273:17477-17482.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17477-17482
-
-
Gotoh, Y.1
Cooper, J.A.2
-
7
-
-
0033554554
-
Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
-
Hoeflich, K. P., W.-C. Yeh, Z. Yao, T. W. Mak, and J. R. Woodgett. 1999. Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1). Oncogene 18:5814-5820.
-
(1999)
Oncogene
, vol.18
, pp. 5814-5820
-
-
Hoeflich, K.P.1
Yeh, W.-C.2
Yao, Z.3
Mak, T.W.4
Woodgett, J.R.5
-
8
-
-
0030825190
-
MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemopterous
-
Holland, P. M., M. Suzanne, J. S. Campbell, S. Noselli, and J. A. Cooper. 1997. MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemopterous. J. Biol. Chem. 272:24994-24998.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24994-24998
-
-
Holland, P.M.1
Suzanne, M.2
Campbell, J.S.3
Noselli, S.4
Cooper, J.A.5
-
10
-
-
0024393963
-
Thioredoxin and glutaredoxin systems
-
Holmgren, A. 1989. Thioredoxin and glutaredoxin systems. J. Biol. Chem. 264:13963-13966.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13963-13966
-
-
Holmgren, A.1
-
11
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo, H., E. Nishida, K. Irie, P. ten Dijke, M. Saitoh, T. Moriguchi, M. Takagi, K. Matsumoto, K. Miyazono, and Y. Gotoh. 1997. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275:90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
12
-
-
0032054723
-
Signal transduction by the c-Jun N-terminal kinase (JNK)-from inflammation to development
-
Ip, Y. T., and R. J. Davis. 1998. Signal transduction by the c-Jun N-terminal kinase (JNK)-from inflammation to development. Curr. Opin. Cell Biol. 10:205-219.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 205-219
-
-
Ip, Y.T.1
Davis, R.J.2
-
14
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis, J. M., and J. Avruch. 1996. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271:24313-24316.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
15
-
-
0033605292
-
Signaling by the germinal center kinase family of protein kinases
-
Kyriakis, J. M. 1999. Signaling by the germinal center kinase family of protein kinases. J. Biol. Chem. 274:5259-5262.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5259-5262
-
-
Kyriakis, J.M.1
-
16
-
-
0008206988
-
TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival
-
Lee, S. Y., A. Reichlin, A. Santana, K. A. Sokol, M. C. Nussenzweig, and Y. Choi. 1997. TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival. Immunity 7:703-713.
-
(1997)
Immunity
, vol.7
, pp. 703-713
-
-
Lee, S.Y.1
Reichlin, A.2
Santana, A.3
Sokol, K.A.4
Nussenzweig, M.C.5
Choi, Y.6
-
17
-
-
0032484215
-
Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3
-
Leung, I. W.-L., and N. Lassam. 1998. Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3. J. Biol. Chem. 273:32408-32415.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32408-32415
-
-
Leung, I.W.-L.1
Lassam, N.2
-
18
-
-
0031714501
-
Molecular determinants of NF-κB-inducing kinase action
-
Lin, X., Y. Mu, E. T. Cunningham, Jr., K. B. Marcu, R. Geleziunas, and W. C. Greene. 1998. Molecular determinants of NF-κB-inducing kinase action. Mol. Cell. Biol. 18:5899-5907.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5899-5907
-
-
Lin, X.1
Mu, Y.2
Cunningham E.T., Jr.3
Marcu, K.B.4
Geleziunas, R.5
Greene, W.C.6
-
19
-
-
0030298294
-
Dissection of TNF receptor-1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
-
Liu, Z.-G., H. Hsu, D. V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor-1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87:565-576.
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.-G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
20
-
-
0029811985
-
Oligomerization activates c-Raf-1 through a Ras-dependent mechanism
-
Luo, Z., G. Tzivion, P. J. Belshaw, D. Vavvas, M. Marshall, and J. Avruch. 1996. Oligomerization activates c-Raf-1 through a Ras-dependent mechanism. Nature 383:181-184.
-
(1996)
Nature
, vol.383
, pp. 181-184
-
-
Luo, Z.1
Tzivion, G.2
Belshaw, P.J.3
Vavvas, D.4
Marshall, M.5
Avruch, J.6
-
21
-
-
0029028962
-
Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor
-
Maeda, T., M. Takekawa, and H. Saito. 1995. Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 269:554-558.
-
(1995)
Science
, vol.269
, pp. 554-558
-
-
Maeda, T.1
Takekawa, M.2
Saito, H.3
-
22
-
-
0031017618
-
MAP3K-related kinase involved in NF-κB induction by TNF, CD-95 and IL-1
-
Malinin, N. L., M. P. Boldin, A. V. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κB induction by TNF, CD-95 and IL-1. Nature 385:540-544.
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
Wallach, D.4
-
23
-
-
0033587691
-
Crystallographic analysis of CD40 recognition and signaling by human TRAF2
-
McWhirter, S. M., S. S. Pullen, J. M. Holton, J. J. Crute, M. R. Kehry, and T. Alber. 1999. Crystallographic analysis of CD40 recognition and signaling by human TRAF2. Proc. Natl. Acad. Sci. USA 96:8408-8413.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8408-8413
-
-
McWhirter, S.M.1
Pullen, S.S.2
Holton, J.M.3
Crute, J.J.4
Kehry, M.R.5
Alber, T.6
-
24
-
-
0024425516
-
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α
-
Meier, B., H. H. Radeke, S. Selle, M. Younes, H. Seis, K. Resch, and G. G. Habermehl. 1989. Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α. Biochem. J. 263:539-545.
-
(1989)
Biochem. J.
, vol.263
, pp. 539-545
-
-
Meier, B.1
Radeke, H.H.2
Selle, S.3
Younes, M.4
Seis, H.5
Resch, K.6
Habermehl, G.G.7
-
25
-
-
0033179775
-
Loss of Daxx, a promiscuously interacting protein results in extensive apoptosis in early mouse development
-
Michaelson, D. Bader, F. Kuo, C. Kozak, and P. Leder. 1999. Loss of Daxx, a promiscuously interacting protein results in extensive apoptosis in early mouse development. Genes Dev. 13:1918-1923.
-
(1999)
Genes Dev.
, vol.13
, pp. 1918-1923
-
-
Bader, D.1
Kuo, F.2
Kozak, C.3
Leder, P.4
-
26
-
-
0031013545
-
Activation of SAPK/JNK by TNF receptor-1 through a noncytotoxic TRAF2-dependent pathway
-
Natoli, G., A. Costanzo, A. Ianni, D. J. Templeton, J. R. Woodgett, C. Balsano, and M. Levrero. 1997. Activation of SAPK/JNK by TNF receptor-1 through a noncytotoxic TRAF2-dependent pathway. Science 275:200-203.
-
(1997)
Science
, vol.275
, pp. 200-203
-
-
Natoli, G.1
Costanzo, A.2
Ianni, A.3
Templeton, D.J.4
Woodgett, J.R.5
Balsano, C.6
Levrero, M.7
-
27
-
-
0033580466
-
The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji, J., K. Kishioto, A. Hiyama, J.-I. Inoue, Z. Cao, and K. Matsumoto. 1999. The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398:252-256.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishioto, K.2
Hiyama, A.3
Inoue, J.-I.4
Cao, Z.5
Matsumoto, K.6
-
28
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
Nishitoh, H., M. Saitoh, Y. Mochida, K. Takeda, H. Nakano, M. Rothe, K. Miyazono, and H. Ichijo. 1998. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell 2:389-395.
-
(1998)
Mol. Cell
, vol.2
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
Miyazono, K.7
Ichijo, H.8
-
29
-
-
0001033803
-
Structural basis for self-association and receptor recognition of human TRAF2
-
Park, Y. C., V. Burkitt, V., A. R. Villa, L. Tong, and H. Wu. 1999. Structural basis for self-association and receptor recognition of human TRAF2. Nature 398:533-538.
-
(1999)
Nature
, vol.398
, pp. 533-538
-
-
Park, Y.C.1
V Burkitt, V.2
Villa, A.R.3
Tong, L.4
Wu, H.5
-
30
-
-
0030815562
-
Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK
-
Posas, F., and H. Saito. 1997. Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK. Science 276:1702-1705.
-
(1997)
Science
, vol.276
, pp. 1702-1705
-
-
Posas, F.1
Saito, H.2
-
31
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75-kDa tumor necrosis factor receptor
-
Rothe, M., S. C. Wong, W. J. Henzel, and D. V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75-kDa tumor necrosis factor receptor. Cell 78:681-692.
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
Goeddel, D.V.4
-
32
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh, M., H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Y. Sawada, M. Kawabata, K. Miyazono, and H. Ichyo. 1998. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17:2596-2606.
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichyo, H.9
-
33
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
34
-
-
0031437885
-
Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathway
-
Shi, C.-S., and J. H. Kehrl. 1997. Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2- and germinal center kinase related-dependent pathway. J. Biol. Chem. 272:32102-32107.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32102-32107
-
-
Shi, C.-S.1
Kehrl, J.H.2
-
35
-
-
0033568595
-
TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related
-
Shi, C.-S., A. Leonardi, J. Kyriakis, U. Siebenlist, and J. H. Kehrl. 1999. TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related. J. Immunol. 163:3279-3285.
-
(1999)
J. Immunol.
, vol.163
, pp. 3279-3285
-
-
Shi, C.-S.1
Leonardi, A.2
Kyriakis, J.3
Siebenlist, U.4
Kehrl, J.H.5
-
36
-
-
0033229827
-
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs)
-
Torii, S., D. A. Egan, R. A. Evans, and J. C. Reed. 1999. Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs). EMBO J. 18:6037-6049.
-
(1999)
EMBO J.
, vol.18
, pp. 6037-6049
-
-
Torii, S.1
Egan, D.A.2
Evans, R.A.3
Reed, J.C.4
-
37
-
-
0030786344
-
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase
-
Tournier, C., A. J. Whitmarsh, J. Cavanagh, T. Barrett, and R. J. Davis. 1997. Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc. Natl. Acad. Sci. USA 94:7337-7342.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7337-7342
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
38
-
-
0027333425
-
Tumor necrosis factor, other cytokines and disease
-
Tracey, K. J., and A. Cerami. 1993. Tumor necrosis factor, other cytokines and disease. Annu. Rev. Cell Biol. 9:317-343.
-
(1993)
Annu. Rev. Cell Biol.
, vol.9
, pp. 317-343
-
-
Tracey, K.J.1
Cerami, A.2
-
39
-
-
0029114596
-
Two tumour necrosis factor receptors: Structure and function
-
Vandenabeele, P., W. Declercq, R. Beyaert, and W. Fiers. 1995. Two tumour necrosis factor receptors: structure and function. Trends Cell Biol. 5:392-399.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 392-399
-
-
Vandenabeele, P.1
Declercq, W.2
Beyaert, R.3
Fiers, W.4
-
40
-
-
0031587883
-
Daxx, a novel Fas-binding protein that activates JNK and apoptosis
-
Yang, X., R. Khosravi-Far, H. Y. Chang, and D. Baltimore. 1997. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89:1067-1076.
-
(1997)
Cell
, vol.89
, pp. 1067-1076
-
-
Yang, X.1
Khosravi-Far, R.2
Chang, H.Y.3
Baltimore, D.4
-
41
-
-
0031463025
-
Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
Yeh, W.-C., A. Shahinian, D. Speiser, J. Kraunus, F. Billia, A. Wakeham, J. L. de la Pompa, D. Ferrick, B. Hum, N. Iscove, P. Ohashi, M. Rothe, D. V. Goeddel, and T. W. Mak. 1997. Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 7:715-725.
-
(1997)
Immunity
, vol.7
, pp. 715-725
-
-
Yeh, W.-C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
De La Pompa, J.L.7
Ferrick, D.8
Hum, B.9
Iscove, N.10
Ohashi, P.11
Rothe, M.12
Goeddel, D.V.13
Mak, T.W.14
-
42
-
-
0032575591
-
Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38
-
Yuasa, T., S. Ohno, J. H. Kehrl, and J. M. Kyriakis. 1998. Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. J. Biol. Chem. 273:22681-22692.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22681-22692
-
-
Yuasa, T.1
Ohno, S.2
Kehrl, J.H.3
Kyriakis, J.M.4
|