TAK1 is critical for IκB kinase-mediated activation of the NF-κB pathway

Journal of Molecular Biology

Volumn 326, Issue 1, 2003, Pages 105-115

  Takaesu, Giichi ^a   Surabhi, Rama M ^a   Park, Kyu Jin ^a   Ninomiya Tsuji, Jun ^b   Matsumoto, Kunihiro ^c   Gaynor, Richard B ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

I B kinase; NF B; RNA interference; Signal transduction; TAK1

Indexed keywords

CYTOKINE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; PHOSPHOTRANSFERASE; RNA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHUK PROTEIN, HUMAN; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; MAP KINASE KINASE KINASE 7; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2;

ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME BINDING; FIBROBLAST; GENETIC PROCEDURES; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HELA CELL; METABOLISM; SIGNAL TRANSDUCTION;

ENZYME ACTIVATION; GENE EXPRESSION; HELA CELLS; HUMANS; I-KAPPA B KINASE; INTERLEUKIN-1; MAP KINASE KINASE KINASES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037422858     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)01404-3     Document Type: Article

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