Measuring and modeling chloride-hydroxyl exchange in the guinea-pig ventricular myocyte

Biophysical Journal

Volumn 94, Issue 6, 2008, Pages 2385-2403

  Niederer, S A ^a,b   Swietach, P ^a   Wilson, D A ^a   Smith, N P ^b   Vaughan Jones, R D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANION TRANSPORT PROTEIN; BICARBONATE SODIUM COTRANSPORTER; CHLORIDE; HYDROXYL RADICAL; PROTON;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOPHYSICS; CHEMISTRY; CYTOLOGY; GUINEA PIG; HEART VENTRICLE; METABOLISM; METHODOLOGY; MUSCLE CELL; PH; THEORETICAL MODEL;

ANIMALS; ANION TRANSPORT PROTEINS; BIOPHYSICS; CHLORIDES; GUINEA PIGS; HEART VENTRICLES; HYDROGEN-ION CONCENTRATION; HYDROXYL RADICAL; MODELS, BIOLOGICAL; MODELS, THEORETICAL; MUSCLE CELLS; PROTONS; SODIUM-BICARBONATE SYMPORTERS;

EID: 42549134089     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.107.118885     Document Type: Article

References (46)

1. 2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes. J. Physiol. 529: 661-668.
2. Bountra, C., and R. Vaughan-Jones. 1989. Effect of intracellular and extracellular pH on contraction in isolated, mammalian cardiac muscle. J. Physiol. 418:163-187.
3. Komukai, K., F. Brette, C. Pascarel, and C. H. Orchard. 2002. Electrophysiological response of rat ventricular myocytes to acidosis. Am. J. Physiol. Heart Circ. Physiol. 283:H412-H422.
4. Leem, C. H., D. Lagadic-Gossmann, and R. D. Vaughan-Jones. 1999. Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte. J. Physiol. 517:159-180.
5. Poole, R. C., and A. P. Halestrap. 1993. Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am. J. Physiol. Cell Physiol. 264:C761-C782.
6. Sun, B., C. H. Leem, and R. D. Vaughan-Jones. 1996. Novel chloride- dependent acid loader in the guinea-pig ventricular myocyte: part of a dual acid-loading mechanism. J. Physiol. 495:65-82.
7. Leem, C. H., and R. D. Vaughan-Jones. 1998. Sarcolemmal mechanisms for pHi recovery from alkalosis in the guinea-pig ventricular myocyte. J. Physiol. 509:487-496.
8. - exchange in ventricular myocytes. Biophys. J. 74:A160.
9. Leem, C. H. and R. D. Vaughan-Jones. 1997. Chloride-hydroxyl exchange in the guinea-pig ventricular myocyte: no role for bicarbonate. J. Mol. Cell. Cardiol. 29:2483-2489.
10. Alper, S. L. 2006. Molecular physiology of SLC4 anion exchangers. Exp. Physiol. 91:153-161.
11. Alvarez, B. V., D. M. Kieller, A. L. Quon, D. Markovich, and J. R. Casey. 2004. SLC26A6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart. J. Physiol. 561:721-734.
12. Xie, Q., R. Welch, A. Mercado, M. F. Romero, and D. B. Mount. 2002. Molecular characterization of the murine SLC26A6 anion exchanger: functional comparison with SLC26A1. Am. J. Physiol. 283:F826-F838.
13. 3 transport in cystic fibrosis. EMBO J. 21:5662-5672.
14. - exchange by SLC26A3 and SLC26A6. J. Gen. Physiol. 127:511-524.
15. Chernova, M. N., L. Jiang, D. J. Friedman, R. B. Darman, H. Lohi, J. Kere, D. H. Vandorpe, and S. L. Alper. 2005. Functional comparison of mouse SLC26A6 anion exchanger with human SLC26A6 polypeptide variants: differences in anion selectivity, regulation, and electro-genicity. J. Biol. Chem. 280:8564-8580.
16. - antiporters. Am. J. Physiol. 40:C1612-C1628.
17. Lagadic-Gossmann, D., K. J. Buckler, and R. D. Vaughan-Jones. 1992. Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte. J. Physiol. 458:361-384.
18. Thomas, J. A., R. N. Buchsbaum, A. Zimniak, and E. Racker. 1979. Intracellular pH measurements in Ehrlich ascites tumor-cells utilizing spectroscopic probes generated in situ. Biochemistry. 18:2210-2218.
19. Kleyman, T. R., and E. J. Cragoe. 1988. Amiloride and its analogs as tools in the study of ion transport. J. Membr. Biol. 105:1-21.
20. Zaniboni, M., P. Swietach, A. Rossini, T. Yamamoto, K. W. Spitzer, and R. D. Vaughan-Jones. 2003. Intracellular proton mobility and buffering power in cardiac ventricular myocytes from rat, rabbit, and guinea-pig. Am. J. Physiol. 285:H1236-H1246.
21. Swietach, P., and R. D. Vaughan-Jones. 2005. Relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes. J. Physiol. 566:793-806.
22. Yamamoto, T., P. Swietach, A. Rossini, S. H. Loh, R. D. Vaughan- Jones, and K. W. Spitzer. 2005. Functional diversity of electrogenic sodium-bicarbonate cotransport in ventricular myocytes from rat, rabbit and guinea-pig. FASEB J. 19:A1632.
23. Fozzard, H. A., and C. O. Lee. 1976. Influence of changes in external potassium and chloride ions on membrane potential and intracellular potassium ion activity in rabbit ventricular muscle. J. Physiol. 256:663-689.
24. + exchanger in renal microvillus membrane- vesicles. Nature. 299:161-163.
25. - cotransport by cGMP and atrial natriuretic factor. J. Gen. Physiol. 100:89-114.
26. - homeostasis and volume regulation of the cardiac cell. Phil. Trans. Roy. Soc. A. Math. Phys. Eng. Sci. 364:1245-1265.
27. Vaughan-Jones, R. D. 1979. Regulation of chloride in quiescent sheep- heart Purkinje fibers studied using intracellular chloride and pH-sensitive micro-electrodes. J. Physiol. 295:111-137.
28. Vaughan-Jones, R. D. 1986. An investigation of chloride-bicarbonate exchange in the sheep cardiac Purkinje fiber. J. Physiol. 379:377-406.
29. Carmeliet, E. E. 1961. Chloride ions and the membrane potential of Purkinje fibers. J. Physiol. 156:375-388.
30. Swietach, P., C. H. Leem, K. W. Spitzer, and R. D. Vaughan-Jones. 2005. Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes. Biophys. J. 88:3018-3037.
31. van Beaumont, W., J. C. Strand, J. S. Petrofsky, S. G. Hipskind, and J. E. Greenleaf. 1973. Changes in total plasma content of electrolytes and proteins with maximal exercise. J. Appl. Physiol. 34:102-106.
32. Vaughan-Jones, R., and K. Spitzer. 2002. Role of bicarbonate in the regulation of intracellular pH in the mammalian ventricular myocyte. Biochem. Cell Biol. 80:579-596.
33. - uptake in apical membrane-vesicles of rat distal colon. Am. J. Physiol. 264:G874-G879.
34. - conductance. Am. J. Physiol. 242:G272-G280.
35. + exchange system in rat brain synaptosomes. Interdependence of internal and external pH control of the exchange activity. J. Biol. Chem. 260:9678-9684.
36. + exchange in sheep cardiac Purkinje fibers. J. Mol. Cell. Cardiol. 29:1131-1140.
37. - affinity. Biochemistry. 35:15228-15235.
38. Stein, W. D. 1986. Transport and Diffusion Across Cell Membranes. Academic Press, San Diego, CA.
39. Papageorgiou, P., B. E. Shmukler, A. K. Stuart-Tilley, L. Jiang, and S. L. Alper. 2001. AE anion exchangers in atrial tumor cells. Am. J. Physiol. 280:H937-H945.
40. Knauf, F., C.-L. Yang, R. B. Thomson, S. A. Mentone, G. Giebisch, and P. S. Aronson. 2001. Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc. Natl. Acad. Sci. USA. 98:9425-9430.
41. Waldegger, S., I. Moschen, A. Ramirez, R. J. H. Smith, H. Ayadi, F. Lang, and C. Kubisch. 2001. Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family. Genomics. 72:43-50.
42. + exchange in the sheep cardiac Purkinje fiber. J. Physiol. 428:441-466.
43. + exchanger. J. Gen. Physiol. 92:239-261.
44. + exchangers by measurement of reverse mode reaction. J. Biol. Chem. 278:43580-43585.
45. + exchanger NHE-1 by cytoplasmic acidification and mitogens. EMBO Rep. 5:91-96.
46. Smith, N. P., and E. J. Crampin. 2004. Development of models of active ion transport for whole-cell modeling: cardiac sodium-potassium pump as a case study. Prog. Biophys. Mol. Biol. 85:387-405.