Intra-tumoural extra-cellular pH: A useful parameter of response to chemotherapy in syngeneic tumour lines

British Journal of Cancer

Volumn 100, Issue 8, 2009, Pages 1287-1291

  Lindner, D ^a   Raghavan, D ^a  

^a TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

Chemotherapy; Extra cellular; Intra tumoural; ph; Response; Syngeneic tumour

Indexed keywords

DOXORUBICIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CANCER CHEMOTHERAPY; CELL PH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTRODE; LEUKEMIA P 388 CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SAMPLE; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR CELL DESTRUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TUMOR; CYCLOPHOSPHAMIDE; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; DRUG TOLERANCE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LEUKEMIA P388; MICE; MICE, INBRED C57BL; TUMOR MARKERS, BIOLOGICAL;

EID: 64949196701     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605022     Document Type: Article

References (15)

1. Budd GT, Cristofanilli M, Ellis MJ, Stopeck A, Borden E, Miller MC, Matera J, Repollet M, Doyle GV, Terstappen LW, Hayes DF (2006) Circulating tumor cells versus imaging - predicting overall survival in metastatic breast cancer. Clin Cancer Res 12: 6403-6409
2. Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, Reuben JM, Doyle GV, Allard WJ, Terstappen LW, Hayes DF (2004) Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med 351: 781-791
3. de Bono JS, Scher HI, Montgomery RB, Parker C, Miller MC, Tissing H, Doyle GV, Terstappen LW, Pienta KJ, Raghavan D (2008) Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 14: 6302-6309
4. Ganapathi R, Schmidt H, Grabowski D, Melia M, Ratliff N (1988) Modulation in vitro and in vivo of cytotoxicity but not cellular levels of doxorubicin by the calmodulin inhibitor trifluoperazine is dependent on the level of resistance. Br J Cancer 58: 335-340
5. Husband JE, Schwartz LH, Spencer J, Ollivier L, King DM, Johnson R, Reznek R (2004) Evaluation of the response to treatment of solid tumours - a consensus statement of the International Cancer Imaging Society. Br J Cancer 90: 2256-2260
6. Hussain M, Tangen CM, Higano C, Schelhammer PF, Faulkner J, Crawford ED, Wilding G, Akdas A, Small EJ, Donnelly B, Mac Vicar G, Raghavan D (2006) Absolute prostate-specific antigen value after androgen deprivation is a strong independent predictor of survival in new metastatic prostate cancer: data from Southwest Oncology Group Trial 9346 (INT-0162). J Clin Oncol 24: 3984-3990
7. Lee YJ, Song JJ, Kim JH, Kim HR, Song YK (2004) Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway. Exp Cell Res 293: 129-143
8. Meurette O, Huc L, Rebillard A, Le Moigne G, Lagadic-Gossmann D, Dimanche-Boitrel MT (2005) TRAIL (TNF-related apoptosis-inducing ligand) induces necrosis-like cell death in tumor cells at acidic extracellular pH. Ann NY Acad Sci 1056: 379-387
9. Meurette O, Rebillard A, Huc L, Le Moigne G, Merino D, Micheau O, Lagadic-Gossmann D, Dimanche-Boitrel MT (2007) TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions. Cancer Res 67: 218-226
10. Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren JT, Bokesch H, Kenney S, Boyd MR (1990) New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107-1112
11. Therasse P, Le Cesne A, Van Glabbeke M, Verweij J, Judson I (2005) RECIST vs WHO: prospective comparison of response criteria in an EORTC phase II clinical trial investigating ET-743 in advanced soft tissue sarcoma. Eur J Cancer 41: 1426-1430
12. Tiu RV, Mountantonakis SE, Dunbar AJ, Schreiber Jr MJ (2007) Tumor lysis syndrome. Semin Thromb Hemost 33: 397-407
13. Tredan O, Galmarini CM, Patel K, Tannock IF (2007) Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst 99: 144-1454
14. Warr D, McKinney S, Tannock I (1984) Influence of measurement error on assessment of response to anticancer chemotherapy: proposal for new criteria of tumor response. J Clin Oncol 2: 1040-1046
15. Wike-Hooley JL, van den Berg AP, van der Zee J, Reinhold HS (1985) Human tumour pH and its variation. Eur J Cancer Clin Oncol 21: 785-791