The role of carbonic anhydrase 9 in regulating extracellular and intracellular pH in three-dimensional tumor cell growths

Journal of Biological Chemistry

Volumn 284, Issue 30, 2009, Pages 20299-20310

  Swietach, Pawel ^a   Patiar, Shalini ^b   Supuran, Claudiu T ^c   Harris, Adrian L ^b   Vaughan Jones, Richard D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONIC ANHYDRASE; EMISSION RATIO; EMPTY VECTOR; EXTRACELLULAR; EXTRACELLULAR SPACE; FLUORESCENT DYES; HUMAN COLON; INTRACELLULAR PH; ISOFORM; MEMBRANE-IMPERMEANT; MULTICELLULAR SPHEROID; MULTICELLULAR STRUCTURE; NET EFFECT; TUMOR DEVELOPMENT; TUMOR PROLIFERATION;

BODY FLUIDS; CELL MEMBRANES; ENZYME ACTIVITY; ENZYMES; GROWTH KINETICS; LACTIC ACID; ORGANIC ACIDS; OXYGENATION; TUMORS;

PH EFFECTS;

BICARBONATE; CARBON DIOXIDE; CARBONATE DEHYDRATASE IX; FLUORESCENT DYE; HYDROGEN; ISOENZYME; LACTIC ACID;

ARTICLE; CARBON DIOXIDE EXCRETION; CARCINOGENESIS; CELL GROWTH; CELL MEMBRANE TRANSPORT; CELL PH; CELL PROLIFERATION; CELL STRAIN HCT116; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR SPACE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MULTICELLULAR SPHEROID; OXYGENATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTON TRANSPORT; REGULATORY MECHANISM; TUMOR GROWTH;

ACIDS; ANTIGENS, NEOPLASM; BICARBONATES; CARBON DIOXIDE; CARBONIC ANHYDRASES; CARCINOMA; CELL LINE, TUMOR; COLONIC NEOPLASMS; FLUORESCEIN; GENE EXPRESSION; HUMANS; HYDROGEN-ION CONCENTRATION; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 67749145635     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.006478     Document Type: Article

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