Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: Distribution and functional activity

American Journal of Physiology - Cell Physiology

Volumn 286, Issue 6 55-6, 2004, Pages

  Sennoune, Souad R ^a   Bakunts, Karina ^a   Martínez, Gloria M ^a   Chua Tuan, Jenny L ^a   Kebir, Yamina ^a   Attaya, Mohamed N ^a   Martínez Zaguilán, Raul ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

Bicarbonate transport; Intracellular pH; Metastasis; Migration; Sodium ion hydrogen ion exchanger

Indexed keywords

PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ACIDITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL MEMBRANE; CELL ORGANELLE; CELL SURFACE; CONTROLLED STUDY; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; METASTASIS; PH; PHENOTYPE; PRIORITY JOURNAL;

ACID-BASE EQUILIBRIUM; BICARBONATES; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; ENZYME INHIBITORS; EXTRACELLULAR FLUID; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHENOTYPE; SODIUM-HYDROGEN ANTIPORTER; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 2442560191     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00407.2003     Document Type: Article

References (59)

1. Albuquerque ML and Flozak AS. Lamellipodial motility in wounded endothelial cells exposed to physiologic flow is associated with different patterns of beta 1-integrin and vinculin localization. J Cell Physiol 195: 50-60, 2003.
2. Bernstein BW, Painter WB, Chen H, Minamide LS, Abe H, and Bamburg JR. Intracellular pH modulation of ADF/cofilin proteins. Cell Motil Cytoskeleton 47: 319-336, 2000.
3. Bowman EJ, Gustafson KR, Bowman BJ, and Boyd MR. Identification of a new chondropsin class of antitumor compound that selectively inhibits V-ATPases. J Biol Chem 278: 44147-44152, 2003.
4. +)-ATPase. Nat Med 2: 470-472, 1996.
5. Bretscher MS and Aguado-Velasco C. EGF induces recycling membrane to form ruffles. Curr Biol 8: 721-724, 1998.
6. + V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways. J Exp Biol 203: 137-145, 2000.
7. +)-ATPase in apical membranes from rat distal colon. J Biol Chem 274: 19693-19698, 1999.
8. + translocation. Mol Cell 6: 1425-1436, 2000.
9. Frattini A, Orchard PJ, Sobacchi C, Giliani S, Abinun M, Mattsson JP, Keeling DJ, Andersson AK, Wallbrandt P, Zecca L, Notarangelo LD, Vezzoni P, and Villa A. Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis. Nat Genet 25: 343-346, 2000.
10. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. Am J Physiol Cell Physiol 267: C195-C203, 1994.
11. + exchange by serum. J Biol Chem 266: 1551-1556, 1991.
12. Gillies RJ, Martínez-Zaguilán R, Martínez GM, Serrano R, and Perona R. Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proc Natl Acad Sci USA 87: 7414-7418, 1990.
13. +-ATPase. Annu Rev Physiol 58: 427-445, 1996.
14. +-ATPase. Proc Natl Acad Sci USA 92: 5965-5968, 1995.
15. Griffiths JR. Are cancer cell acidic? Br J Cancer 64: 425-427, 1991.
16. 2 gradients in solid tumors in vivo: high resolution measurements reveal a lack of correlation. Nat Med 3: 177-182, 1997.
17. +-ATPase contains a filamentous actin binding site. J Biol Chem 275: 32331-32337, 2000.
18. Kubota S and Seyama Y. Overexpression of vacuolar ATPase 16-kDa subunit in 10T1/2 fibroblasts enhances invasion with concomitant induction of matrix metalloproteinase-2. Biochem Biophys Res Commun 278: 390-394, 2000.
19. Lang T, Wacker I, Wunderlich I, Rohrbach A, Giese G, Soldati T, and Almers W. Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells. Biophys J 78: 2863-2877, 2000.
20. Laurencot CM, Andrews PA, and Kennedy KA. Inhibitors of intracellular pH regulation induce cisplatin resistance in EMT6 mouse mammary tumor cells. Oncol Res 7: 363-369, 1995.
21. Lippincott-Schwartz J, Roberts TH, and Hirschberg K. Secretory protein trafficking and organelle dynamics in living cells. Annu Rev Cell Dev Biol 16: 557-589, 2000.
22. Lowry OH, Rosebrough NJ, Farr AL, and Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
23. Mareel MM, Van Roy FM, and De Baetseller P. The invasive phenotypes. Cancer Metastasis Rev 9: 45-62, 1990.
24. Marks PW and Maxfield FR. Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils. J Cell Biol 110: 43-52, 1990.
25. Martínez-Zaguilán R. Angiostatin's partners. Science 284: 433-434, 1999.
26. +-ATPases are functionally expressed in plasma membranes of human tumor cells. Am J Physiol Cell Physiol 265: C1015-C1029, 1993.
27. in in human melanoma cells with different metastatic potential. J Cell Physiol 176: 196-205, 1998.
28. +-ATPase in drug-resistant human breast carcinoma cell lines. Biochem Pharmacol 57: 1037-1046, 1999.
29. Martínez-Zaguilán R, Seftor EA, Seftor RE, Chu YW, Gillies RJ, and Hendrix MJ. Acidic pH enhances the invasive behavior of human melanoma cells. Clin Exp Metastasis 14: 176-186, 1996.
30. Matrisian LM. The matrix-degrading metalloproteinases. Bioessays 14: 455-463, 1992.
31. McNeil PL. Repairing a torn cell surface: make way, lysosomes to rescue. J Cell Sci 115: 873-879, 2002.
32. Nanda A, Gukovskaya A, Tseng J, and Grinstein S. Activation of vacuolar-type proton pumps by protein kinase C. Role in neutrophil pH regulation. J Biol Chem 267: 22740-22746, 1992,
33. Nelson N and Harvey WR. Vacuolar and plasma membrane proton adenosinetriphosphatases. Physiol Rev 79: 361-385, 1999.
34. Niessen H, Meisenholder GW, Li HL, Gluck SL, Lee BS, Bowman B, Engler RL, Babior BM, and Gottlieb RA. Granulocyte colony-stimulating factor upregulates the vacuolar proton ATPase in human neutrophils. Blood 90: 4598-4601, 1997.
35. +)-ATPases-nature's most versatile proton pumps. Nat Rev Mol Cell Biol 3: 94-103, 2002.
36. Perona R and Serrano R. Increased pH and tumorigenicity of fibroblasts expressing a yeast proton pump. Nature 334: 438-440, 1988.
37. Pierini LM, Lawson MA, Eddy RJ, Hendey B, and Maxfield FR. Oriented endocytic recycling of alpha 5 beta 1 in motile neutrophils. Blood 29: 2471-2480, 2000.
38. Putnam RW. Intracellular pH regulation. In: Cell Physiology Sourcebook: A Molecular Approach (3rd ed.), edited by Sperelakis N. San Diego, CA: Academic, 2001, p. 357-376.
39. Racker E. Bioenergetics and the problem of tumor growth. Am Sci 60: 56-63, 1972.
40. Raghunand N, Martínez-Zaguilán R, Wright S, and Gillies RJ. pH and drug resistance II: turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. Biochem Pharmacol 57: 1047-1058, 1999.
41. Rojas JG, Sanka SC, Luo D, Martínez GM, and Martí nez-Zaguilán R. Proton pumps, angiogenesis and metastatic breast cancer. Proc Int Soc Optical Engin SPIE 3924: 67-78, 2000.
42. Roos A and Boron WF. Intracellular pH. Physiol Rev 61: 296-434, 1981.
43. Rozhin J, Sameni M, Ziegler G, and Sloane BF. Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res 54: 6517-6525, 1994.
44. Savarese DM, Russell JT, Fatatis A, and Liotta LA. Type IV collagen stimulates an increase in intracellular calcium. Potential role in tumor cell motility. J Biol Chem 267: 21928-21935, 1992.
45. Schlappack OK, Zimmerman A, and Hill RP. Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumor cells. Br J Cancer 64: 663-670, 1991.
46. Selden SC and Schwartz SM. Cytochalasin B inhibition of endothelial proliferation at wound edges in vitro. J Cell Biol 81: 348-354, 1979.
47. Smith AN, Skaug J, Choate KA, Nayir A, Bakkaloglu A, Ozen S, Hulton SA, Sanjad SA, Al-Sabban EA, Lifton RP, Scherer SW, and Karet FE. Mutations in ATP6N1B, encoding a new kidney vacuolar proton pump 116-kDa subunit, cause recessive distal renal tubular acidosis with preserved hearing. Nat Genet 26: 71-75, 2000.
48. Stetler-Stevenson WG. Type IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev 9: 289-303, 1990.
49. Tanigaki K, Sasaki S, and Ohkuma S. In bafilomycin A1-resistant cells, bafilomycin A1 raised lysosomal pH and both prodigiosins and concanamycin A inhibited growth through apoptosis. FEBS Lett 537: 79-84, 2003.
50. Thiebaut F, Currier SJ, Whitaker J, Haugland RP, Gottesman MM, Pastan I, and Willingham MC. Activity of the multidrug transporter results in alkalinization of the cytosol: measurement of cytosolic pH by microinjection of a pH-sensitive dye. J Histochem Cytochem 38: 685-690, 1990.
51. 1 influence cell motility. Biochim Biophys Acta 1452: 285-295, 1999.
52. +-ATPase c subunit gene (ATP6L) in response to anticancer agents. J Biol Chem 277: 36534-36543, 2002.
53. +-ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem 278: 22023-22030, 2003.
54. +-ATPase type in the ruffled borders of osteoclasts. J Cell Biol 111: 1305-1311, 1990.
55. Vassalli JD, Sappino AP, and Belin D. The plasminogen activator/plasmin system. J Clin Invest 88: 1067-1072, 1991.
56. +-V-ATPase to the actin cytoskeleton. J Biol Chem 278: 18499-18505, 2003.
57. Webb SD, Sherratt JA, and Fish RG. Alterations in proteolytic activity at low pH and its association with invasion: a theoretical model. Clin Exp Metastasis 17: 397-407, 1999.
58. Wieczorek H, Gruber G, Harvey WR, Huss M, Merzendorfer H, and Zeiske W. Structure and regulation of insect plasma membrane H+-ATPase. J Exp Biol 203: 127-135, 2000.
59. Xu J, Feng HT, Wang C, Yip KH, Pavlos N, Papadimitriou JM, Wood D, and Zheng MH. Effects of bafilomycin A1: an inhibitor of vacuolar H(+)-ATPases on endocytosis and apoptosis in RAW cells and RAW cell-derived osteoclasts. J Cell Biochem 88: 1256-1264, 2003.