-
1
-
-
0033578005
-
G-protein-coupled receptor heterodimerization modulates receptor function
-
Jordan, B.A.; Devi, L.A. G-protein-coupled receptor heterodimerization modulates receptor function. Nature, 1999, 399, 697-700.
-
(1999)
Nature
, vol.399
, pp. 697-700
-
-
Jordan, B.A.1
Devi, L.A.2
-
2
-
-
60249098735
-
Building a new conceptual framework for receptor heteromers
-
Ferre, S.; Baler, R.; Bouvier, M.; Caron, M.G.; Devi, L.A.; Durroux, T.; Fuxe, K.; George, S.R.; Javitch, J.A.; Lohse, M.J.; Mackie, K.; Milligan, G.; Pfleger, K.D.; Pin, J.P.; Volkow, N.D.; Waldhoer, M.; Woods, A.S.; Franco, R. Building a new conceptual framework for receptor heteromers. Nat. Chem. Biol., 2009, 5, 131-134.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 131-134
-
-
Ferre, S.1
Baler, R.2
Bouvier, M.3
Caron, M.G.4
Devi, L.A.5
Durroux, T.6
Fuxe, K.7
George, S.R.8
Javitch, J.A.9
Lohse, M.J.10
Mackie, K.11
Milligan, G.12
Pfleger, K.D.13
Pin, J.P.14
Volkow, N.D.15
Waldhoer, M.16
Woods, A.S.17
Franco, R.18
-
3
-
-
70349109589
-
GPCR homomers and heteromers: A better choice as targets for drug development than GPCR monomers?
-
Casado, V.; Cortes, A.; Mallol, J.; Perez-Capote, K.; Ferre, S.; Lluis, C.; Franco, R.; Canela, E.I. GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers? Pharmacol. Ther., 2009, 124, 248-257.
-
(2009)
Pharmacol. Ther
, vol.124
, pp. 248-257
-
-
Casado, V.1
Cortes, A.2
Mallol, J.3
Perez-Capote, K.4
Ferre, S.5
Lluis, C.6
Franco, R.7
Canela, E.I.8
-
4
-
-
21344433619
-
Methods to monitor the quaternary structure of G protein-coupled receptors
-
Milligan, G.; Bouvier, M. Methods to monitor the quaternary structure of G protein-coupled receptors. FEBS J., 2005, 272, 2914-2925.
-
(2005)
FEBS J
, vol.272
, pp. 2914-2925
-
-
Milligan, G.1
Bouvier, M.2
-
5
-
-
13444274883
-
Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers
-
El-Asmar, L.; Springael, J.Y.; Ballet, S.; Andrieu, E.U.; Vassart, G.; Parmentier, M. Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers. Mol. Pharmacol., 2005, 67, 460-469.
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 460-469
-
-
El-Asmar, L.1
Springael, J.Y.2
Ballet, S.3
Andrieu, E.U.4
Vassart, G.5
Parmentier, M.6
-
6
-
-
33645802812
-
Allosteric modulation of binding properties between units of chemokine receptor homo-and hetero-oligomers
-
Springael, J.Y.; Le Minh, P.N.; Urizar, E.; Costagliola, S.; Vassart, G.; Parmentier, M. Allosteric modulation of binding properties between units of chemokine receptor homo-and hetero-oligomers. Mol. Pharmacol., 2006, 69, 1652-1661.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 1652-1661
-
-
Springael, J.Y.1
Le Minh, P.N.2
Urizar, E.3
Costagliola, S.4
Vassart, G.5
Parmentier, M.6
-
7
-
-
33646343978
-
Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)
-
Pfleger, K.D.; Eidne, K.A. Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET). Nat. Methods, 2006, 3, 165-174.
-
(2006)
Nat. Methods
, vol.3
, pp. 165-174
-
-
Pfleger, K.D.1
Eidne, K.A.2
-
8
-
-
40349088830
-
G-protein-coupled receptor heteromers: Function and ligand pharmacology
-
Franco, R.; Casado, V.; Cortes, A.; Mallol, J.; Ciruela, F.; Ferre, S.; Lluis, C.; Canela, E.I. G-protein-coupled receptor heteromers: function and ligand pharmacology. Br. J. Pharmacol., 2008, 153(Suppl 1), S90-S98.
-
(2008)
Br. J. Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Franco, R.1
Casado, V.2
Cortes, A.3
Mallol, J.4
Ciruela, F.5
Ferre, S.6
Lluis, C.7
Canela, E.I.8
-
9
-
-
76849085436
-
Receptor-receptor interactions: A novel concept in brain integration
-
Agnati, L.F.; Guidolin, D.; Leo, G.; Carone, C.; Genedani, S.; Fuxe, K. Receptor-receptor interactions: a novel concept in brain integration. Prog. Neurobiol., 2010, 90(2), 157-175.
-
(2010)
Prog. Neurobiol
, vol.90
, Issue.2
, pp. 157-175
-
-
Agnati, L.F.1
Guidolin, D.2
Leo, G.3
Carone, C.4
Genedani, S.5
Fuxe, K.6
-
10
-
-
33845911715
-
Intramembrane receptor-receptor interactions: A novel principle in molecular medicine
-
Fuxe, K.; Canals, M.; Torvinen, M.; Marcellino, D.; Terasmaa, A.; Genedani, S.; Leo, G.; Guidolin, D.; Diaz-Cabiale, Z.; Rivera, A.; Lundstrom, L.; Langel, U.; Narvaez, J.; Tanganelli, S.; Lluis, C.; Ferre, S.; Woods, A.; Franco, R.; Agnati, L.F. Intramembrane receptor-receptor interactions: a novel principle in molecular medicine. J. Neural Transm., 2007, 114, 49-75.
-
(2007)
J. Neural Transm
, vol.114
, pp. 49-75
-
-
Fuxe, K.1
Canals, M.2
Torvinen, M.3
Marcellino, D.4
Terasmaa, A.5
Genedani, S.6
Leo, G.7
Guidolin, D.8
Diaz-Cabiale, Z.9
Rivera, A.10
Lundstrom, L.11
Langel, U.12
Narvaez, J.13
Tanganelli, S.14
Lluis, C.15
Ferre, S.16
Woods, A.17
Franco, R.18
Agnati, L.F.19
-
11
-
-
46249098051
-
Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology
-
Fuxe, K.; Marcellino, D.; Rivera, A.; Diaz-Cabiale, Z.; Filip, M.; Gago, B.; Roberts, D.C.; Langel, U.; Genedani, S.; Ferraro, L.; de la Calle, A.; Narvaez, J.; Tanganelli, S.; Woods, A.; Agnati, L.F. Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology. Brain Res. Rev., 2008, 58, 415-452.
-
(2008)
Brain Res. Rev
, vol.58
, pp. 415-452
-
-
Fuxe, K.1
Marcellino, D.2
Rivera, A.3
Diaz-Cabiale, Z.4
Filip, M.5
Gago, B.6
Roberts, D.C.7
Langel, U.8
Genedani, S.9
Ferraro, L.10
de la Calle, A.11
Narvaez, J.12
Tanganelli, S.13
Woods, A.14
Agnati, L.F.15
-
12
-
-
72449173500
-
Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes
-
Cottet, M.; Albizu, L.; Perkovska, S.; Jean-Alphonse, F.; Rahmeh, R.; Orcel, H.; Mejean, C.; Granier, S.; Mendre, C.; Mouillac, B.; Durroux, T. Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes. Curr. Opin. Pharmacol., 2009, 10(1), 59-66.
-
(2009)
Curr. Opin. Pharmacol
, vol.10
, Issue.1
, pp. 59-66
-
-
Cottet, M.1
Albizu, L.2
Perkovska, S.3
Jean-Alphonse, F.4
Rahmeh, R.5
Orcel, H.6
Mejean, C.7
Granier, S.8
Mendre, C.9
Mouillac, B.10
Durroux, T.11
-
13
-
-
33751195311
-
Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding
-
Albizu, L.; Balestre, M.N.; Breton, C.; Pin, J.P.; Manning, M.; Mouillac, B.; Barberis, C.; Durroux, T. Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding. Mol. Pharmacol., 2006, 70, 1783-1791.
-
(2006)
Mol. Pharmacol
, vol.70
, pp. 1783-1791
-
-
Albizu, L.1
Balestre, M.N.2
Breton, C.3
Pin, J.P.4
Manning, M.5
Mouillac, B.6
Barberis, C.7
Durroux, T.8
-
14
-
-
0035318509
-
Oligomerization of G-protein-coupled transmitter receptors
-
Bouvier, M. Oligomerization of G-protein-coupled transmitter receptors. Nat. Rev. Neurosci., 2001, 2, 274-286.
-
(2001)
Nat. Rev. Neurosci
, vol.2
, pp. 274-286
-
-
Bouvier, M.1
-
15
-
-
17144473106
-
Chemokine receptor homoor heterodimerization activates distinct signaling pathways
-
Mellado, M.; Rodriguez-Frade, J.M.; Vila-Coro, A.J.; Fernandez, S.; Martin de Ana, A.; Jones, D.R.; Toran, J.L.; Martinez, A.C. Chemokine receptor homoor heterodimerization activates distinct signaling pathways. EMBO J., 2001, 20, 2497-2507.
-
(2001)
EMBO J
, vol.20
, pp. 2497-2507
-
-
Mellado, M.1
Rodriguez-Frade, J.M.2
Vila-Coro, A.J.3
Fernandez, S.4
Martin de Ana, A.5
Jones, D.R.6
Toran, J.L.7
Martinez, A.C.8
-
16
-
-
0036878162
-
Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method
-
Filizola, M.; Olmea, O.; Weinstein, H. Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method. Protein Eng., 2002, 15, 881-885.
-
(2002)
Protein Eng
, vol.15
, pp. 881-885
-
-
Filizola, M.1
Olmea, O.2
Weinstein, H.3
-
17
-
-
0042467972
-
Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons
-
Agnati, L.F.; Ferre, S.; Lluis, C.; Franco, R.; Fuxe, K. Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol. Rev., 2003, 55, 509-550.
-
(2003)
Pharmacol. Rev
, vol.55
, pp. 509-550
-
-
Agnati, L.F.1
Ferre, S.2
Lluis, C.3
Franco, R.4
Fuxe, K.5
-
18
-
-
4544278502
-
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors
-
Ciruela, F.; Burgueno, J.; Casado, V.; Canals, M.; Marcellino, D.; Goldberg, S.R.; Bader, M.; Fuxe, K.; Agnati, L.F.; Lluis, C.; Franco, R.; Ferre, S.; Woods, A.S. Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors. Anal. Chem., 2004, 76, 5354-5363.
-
(2004)
Anal. Chem
, vol.76
, pp. 5354-5363
-
-
Ciruela, F.1
Burgueno, J.2
Casado, V.3
Canals, M.4
Marcellino, D.5
Goldberg, S.R.6
Bader, M.7
Fuxe, K.8
Agnati, L.F.9
Lluis, C.10
Franco, R.11
Ferre, S.12
Woods, A.S.13
-
19
-
-
1242276192
-
Roles of G-protein-coupled receptor dimerization
-
Terrillon, S.; Bouvier, M. Roles of G-protein-coupled receptor dimerization. EMBO Rep., 2004, 5, 30-34.
-
(2004)
EMBO Rep
, vol.5
, pp. 30-34
-
-
Terrillon, S.1
Bouvier, M.2
-
20
-
-
23344447877
-
The CXCR1 and CXCR2 receptors form constitutive homo-and heterodimers selectively and with equal apparent affinities
-
Wilson, S.; Wilkinson, G.; Milligan, G. The CXCR1 and CXCR2 receptors form constitutive homo-and heterodimers selectively and with equal apparent affinities. J. Biol. Chem., 2005, 280, 28663-28674.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 28663-28674
-
-
Wilson, S.1
Wilkinson, G.2
Milligan, G.3
-
21
-
-
0035793079
-
Oligomerization of opioid receptors with beta 2-adrenergic receptors: A role in trafficking and mitogen-activated protein kinase activation
-
Jordan, B.A.; Trapaidze, N.; Gomes, I.; Nivarthi, R.; Devi, L.A. Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation. Proc. Natl. Acad. Sci. USA, 2001, 98, 343-348.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 343-348
-
-
Jordan, B.A.1
Trapaidze, N.2
Gomes, I.3
Nivarthi, R.4
Devi, L.A.5
-
22
-
-
0037205489
-
Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization
-
Pfeiffer, M.; Koch, T.; Schroder, H.; Laugsch, M.; Hollt, V.; Schulz, S. Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. J. Biol. Chem., 2002, 277, 19762-19772.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 19762-19772
-
-
Pfeiffer, M.1
Koch, T.2
Schroder, H.3
Laugsch, M.4
Hollt, V.5
Schulz, S.6
-
23
-
-
0037518126
-
Heterodimerization of alpha 2A-and beta 1-adrenergic receptors
-
Xu, J.; He, J.; Castleberry, A.M.; Balasubramanian, S.; Lau, A.G.; Hall, R.A. Heterodimerization of alpha 2A-and beta 1-adrenergic receptors. J. Biol. Chem., 2003, 278, 10770-10777.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 10770-10777
-
-
Xu, J.1
He, J.2
Castleberry, A.M.3
Balasubramanian, S.4
Lau, A.G.5
Hall, R.A.6
-
24
-
-
0141890300
-
Oligomerization of the alpha 1a-and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization
-
Stanasila, L.; Perez, J.B.; Vogel, H.; Cotecchia, S. Oligomerization of the alpha 1a-and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization. J. Biol. Chem., 2003, 278, 40239-40251.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 40239-40251
-
-
Stanasila, L.1
Perez, J.B.2
Vogel, H.3
Cotecchia, S.4
-
25
-
-
0037144542
-
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy
-
Lavoie, C.; Mercier, J.F.; Salahpour, A.; Umapathy, D.; Breit, A.; Villeneuve, L.R.; Zhu, W.Z.; Xiao, R.P.; Lakatta, E.G.; Bouvier, M.; Hebert, T.E. Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy. J. Biol. Chem., 2002, 277, 35402-35410.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 35402-35410
-
-
Lavoie, C.1
Mercier, J.F.2
Salahpour, A.3
Umapathy, D.4
Breit, A.5
Villeneuve, L.R.6
Zhu, W.Z.7
Xiao, R.P.8
Lakatta, E.G.9
Bouvier, M.10
Hebert, T.E.11
-
26
-
-
3142617997
-
Hetero-oligomerization between beta2-and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties
-
Breit, A.; Lagace, M.; Bouvier, M. Hetero-oligomerization between beta2-and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties. J. Biol. Chem., 2004, 279, 28756-28765.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 28756-28765
-
-
Breit, A.1
Lagace, M.2
Bouvier, M.3
-
27
-
-
1242274647
-
Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns
-
Terrillon, S.; Barberis, C.; Bouvier, M. Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns. Proc. Natl. Acad. Sci. USA, 2004, 101, 1548-1553.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1548-1553
-
-
Terrillon, S.1
Barberis, C.2
Bouvier, M.3
-
28
-
-
20544449873
-
Principles: A model for the allosteric interactions between ligand binding sites within a dimeric GPCR
-
Durroux, T. Principles: a model for the allosteric interactions between ligand binding sites within a dimeric GPCR. Trends Pharmacol. Sci., 2005, 26, 376-384.
-
(2005)
Trends Pharmacol. Sci
, vol.26
, pp. 376-384
-
-
Durroux, T.1
-
29
-
-
0035958027
-
Homo-and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A)
-
Pfeiffer, M.; Koch, T.; Schroder, H.; Klutzny, M.; Kirscht, S.; Kreienkamp, H.J.; Hollt, V.; Schulz, S. Homo-and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A). J. Biol. Chem., 2001, 276, 14027-14036.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 14027-14036
-
-
Pfeiffer, M.1
Koch, T.2
Schroder, H.3
Klutzny, M.4
Kirscht, S.5
Kreienkamp, H.J.6
Hollt, V.7
Schulz, S.8
-
30
-
-
21244460359
-
Glycoprotein hormone receptors: Link between receptor homodimerization and negative cooperativity
-
Urizar, E.; Montanelli, L.; Loy, T.; Bonomi, M.; Swillens, S.; Gales, C.; Bouvier, M.; Smits, G.; Vassart, G.; Costagliola, S. Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity. EMBO J., 2005, 24, 1954-1964.
-
(2005)
EMBO J
, vol.24
, pp. 1954-1964
-
-
Urizar, E.1
Montanelli, L.2
Loy, T.3
Bonomi, M.4
Swillens, S.5
Gales, C.6
Bouvier, M.7
Smits, G.8
Vassart, G.9
Costagliola, S.10
-
31
-
-
23344449115
-
Heterodimerization of beta1-and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility
-
Zhu, W.Z.; Chakir, K.; Zhang, S.; Yang, D.; Lavoie, C.; Bouvier, M.; Hebert, T.E.; Lakatta, E.G.; Cheng, H.; Xiao, R.P. Heterodimerization of beta1-and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circ. Res., 2005, 97, 244-255.
-
(2005)
Circ. Res
, vol.97
, pp. 244-255
-
-
Zhu, W.Z.1
Chakir, K.2
Zhang, S.3
Yang, D.4
Lavoie, C.5
Bouvier, M.6
Hebert, T.E.7
Lakatta, E.G.8
Cheng, H.9
Xiao, R.P.10
-
32
-
-
1442284465
-
Allosteric modulation of G-protein coupled receptors
-
Jensen, A.A.; Spalding, T.A. Allosteric modulation of G-protein coupled receptors. Eur. J. Pharm. Sci, 2004, 21, 407-420.
-
(2004)
Eur. J. Pharm. Sci
, vol.21
, pp. 407-420
-
-
Jensen, A.A.1
Spalding, T.A.2
-
33
-
-
0036490942
-
Allosteric binding sites on cell-surface receptors: Novel targets for drug discovery
-
Christopoulos, A. Allosteric binding sites on cell-surface receptors: novel targets for drug discovery. Nat. Rev. Drug Discov., 2002, 1, 198-210.
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 198-210
-
-
Christopoulos, A.1
-
34
-
-
0034616021
-
Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
-
Rocheville, M.; Lange, D.C.; Kumar, U.; Patel, S.C.; Patel, R.C.; Patel, Y.C. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science, 2000, 288, 154-157.
-
(2000)
Science
, vol.288
, pp. 154-157
-
-
Rocheville, M.1
Lange, D.C.2
Kumar, U.3
Patel, S.C.4
Patel, R.C.5
Patel, Y.C.6
-
35
-
-
0034618268
-
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
-
AbdAlla, S.; Lother, H.; Quitterer, U. AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature, 2000, 407, 94-98.
-
(2000)
Nature
, vol.407
, pp. 94-98
-
-
Abdalla, S.1
Lother, H.2
Quitterer, U.3
-
36
-
-
30044447860
-
Heterodimers of alpha1B-and alpha1D-adrenergic receptors form a single functional entity
-
Hague, C.; Lee, S.E.; Chen, Z.; Prinster, S.C.; Hall, R.A.; Minneman, K.P. Heterodimers of alpha1B-and alpha1D-adrenergic receptors form a single functional entity. Mol. Pharmacol., 2006, 69, 45-55.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 45-55
-
-
Hague, C.1
Lee, S.E.2
Chen, Z.3
Prinster, S.C.4
Hall, R.A.5
Minneman, K.P.6
-
37
-
-
33747585593
-
Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors
-
Prinster, S.C.; Holmqvist, T.G.; Hall, R.A. Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors. J. Pharmacol. Exp. Ther., 2006, 318, 974-981.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.318
, pp. 974-981
-
-
Prinster, S.C.1
Holmqvist, T.G.2
Hall, R.A.3
-
38
-
-
33746290412
-
The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization
-
Levoye, A.; Dam, J.; Ayoub, M.A.; Guillaume, J.L.; Couturier, C.; Delagrange, P.; Jockers, R. The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. EMBO J., 2006, 25, 3012-3023.
-
(2006)
EMBO J
, vol.25
, pp. 3012-3023
-
-
Levoye, A.1
Dam, J.2
Ayoub, M.A.3
Guillaume, J.L.4
Couturier, C.5
Delagrange, P.6
Jockers, R.7
-
39
-
-
0043235844
-
Ligand-selective receptor conformations revisited: The promise and the problem
-
Kenakin, T. Ligand-selective receptor conformations revisited: the promise and the problem. Trends Pharmacol. Sci., 2003, 24, 346-354.
-
(2003)
Trends Pharmacol. Sci
, vol.24
, pp. 346-354
-
-
Kenakin, T.1
-
40
-
-
0034714335
-
Oligomerization of mu-and delta-opioid receptors. Generation of novel functional properties
-
George, S.R.; Fan, T.; Xie, Z.; Tse, R.; Tam, V.; Varghese, G.; O'Dowd, B.F. Oligomerization of mu-and delta-opioid receptors. Generation of novel functional properties. J. Biol. Chem., 2000, 275, 26128-26135.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 26128-26135
-
-
George, S.R.1
Fan, T.2
Xie, Z.3
Tse, R.4
Tam, V.5
Varghese, G.6
O'Dowd, B.F.7
-
41
-
-
34547759878
-
Receptor heterodimerization leads to a switch in signaling: Beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers
-
Rozenfeld, R.; Devi, L.A. Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers. FASEB J., 2007, 21, 2455-2465.
-
(2007)
FASEB J
, vol.21
, pp. 2455-2465
-
-
Rozenfeld, R.1
Devi, L.A.2
-
42
-
-
3543083733
-
Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal
-
Lee, S.P.; So, C.H.; Rashid, A.J.; Varghese, G.; Cheng, R.; Lanca, A.J.; O'Dowd, B.F.; George, S.R. Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. J. Biol. Chem., 2004, 279, 35671-35678.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 35671-35678
-
-
Lee, S.P.1
So, C.H.2
Rashid, A.J.3
Varghese, G.4
Cheng, R.5
Lanca, A.J.6
O'Dowd, B.F.7
George, S.R.8
-
43
-
-
33846328669
-
D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum
-
Rashid, A.J.; So, C.H.; Kong, M.M.; Furtak, T.; El-Ghundi, M.; Cheng, R.; O'Dowd, B.F.; George, S.R. D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proc. Natl. Acad. Sci. USA, 2007, 104, 654-659.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 654-659
-
-
Rashid, A.J.1
So, C.H.2
Kong, M.M.3
Furtak, T.4
El-Ghundi, M.5
Cheng, R.6
O'Dowd, B.F.7
George, S.R.8
-
44
-
-
0036780743
-
G-protein-coupled receptor oligomerization and its potential for drug discovery
-
George, S.R.; O'Dowd, B.F.; Lee, S.P. G-protein-coupled receptor oligomerization and its potential for drug discovery. Nat. Rev. Drug Discov., 2002, 1, 808-820.
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 808-820
-
-
George, S.R.1
O'Dowd, B.F.2
Lee, S.P.3
-
45
-
-
0030861647
-
Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
-
Ferre, S.; Fredholm, B.B.; Morelli, M.; Popoli, P.; Fuxe, K. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci., 1997, 20, 482-487.
-
(1997)
Trends Neurosci
, vol.20
, pp. 482-487
-
-
Ferre, S.1
Fredholm, B.B.2
Morelli, M.3
Popoli, P.4
Fuxe, K.5
-
46
-
-
33750289921
-
-
The nigrostriatal DA pathway and Parkinson's disease
-
Fuxe, K.; Manger, P.; Genedani, S.; Agnati, L. The nigrostriatal DA pathway and Parkinson's disease. J. Neural Transm. Suppl., 2006, 71-83.
-
(2006)
J. Neural Transm. Suppl
, pp. 71-83
-
-
Fuxe, K.1
Manger, P.2
Genedani, S.3
Agnati, L.4
-
47
-
-
7944228085
-
Dopamine receptor agonists in the therapy of Parkinson's disease
-
Foley, P.; Gerlach, M.; Double, K.L.; Riederer, P. Dopamine receptor agonists in the therapy of Parkinson's disease. J. Neural Transm., 2004, 111, 1375-1446.
-
(2004)
J. Neural Transm
, vol.111
, pp. 1375-1446
-
-
Foley, P.1
Gerlach, M.2
Double, K.L.3
Riederer, P.4
-
49
-
-
0036009015
-
D1 dopamine receptor: A putative neurochemical and behavioral link to cocaine action
-
Hummel, M.; Unterwald, E.M. D1 dopamine receptor: a putative neurochemical and behavioral link to cocaine action. J. Cell Physiol., 2002, 191, 17-27.
-
(2002)
J. Cell Physiol
, vol.191
, pp. 17-27
-
-
Hummel, M.1
Unterwald, E.M.2
-
50
-
-
0345932930
-
Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens
-
Toda, S.; Alguacil, L.F.; Kalivas, P.W. Repeated cocaine administration changes the function and subcellular distribution of adenosine A1 receptor in the rat nucleus accumbens. J. Neurochem., 2003, 87, 1478-1484.
-
(2003)
J. Neurochem
, vol.87
, pp. 1478-1484
-
-
Toda, S.1
Alguacil, L.F.2
Kalivas, P.W.3
-
51
-
-
0242416171
-
A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation
-
Angulo, E.; Casado, V.; Mallol, J.; Canela, E.I.; Vinals, F.; Ferrer, I.; Lluis, C.; Franco, R. A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation. Brain Pathol., 2003, 13, 440-451.
-
(2003)
Brain Pathol
, vol.13
, pp. 440-451
-
-
Angulo, E.1
Casado, V.2
Mallol, J.3
Canela, E.I.4
Vinals, F.5
Ferrer, I.6
Lluis, C.7
Franco, R.8
-
52
-
-
0028177264
-
Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor
-
Ng, G.Y.; Mouillac, B.; George, S.R.; Caron, M.; Dennis, M.; Bouvier, M.; O'Dowd, B.F. Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. Eur. J. Pharmacol., 1994, 267, 7-19.
-
(1994)
Eur. J. Pharmacol
, vol.267
, pp. 7-19
-
-
Ng, G.Y.1
Mouillac, B.2
George, S.R.3
Caron, M.4
Dennis, M.5
Bouvier, M.6
O'Dowd, B.F.7
-
53
-
-
0029417184
-
Immunological identification of A1 adenosine receptors in brain cortex
-
Ciruela, F.; Casado, V.; Mallol, J.; Canela, E.I.; Lluis, C.; Franco, R. Immunological identification of A1 adenosine receptors in brain cortex. J. Neurosci. Res., 1995, 42, 818-828.
-
(1995)
J. Neurosci. Res
, vol.42
, pp. 818-828
-
-
Ciruela, F.1
Casado, V.2
Mallol, J.3
Canela, E.I.4
Lluis, C.5
Franco, R.6
-
54
-
-
0030567986
-
Dopamine D2 receptor dimers and receptor-blocking peptides. Biochem
-
Ng, G.Y.; O'Dowd, B.F.; Lee, S.P.; Chung, H.T.; Brann, M.R.; Seeman, P.; George, S.R. Dopamine D2 receptor dimers and receptor-blocking peptides. Biochem. Biophys. Res. Commun., 1996, 227, 200-204.
-
(1996)
Biophys. Res. Commun
, vol.227
, pp. 200-204
-
-
Ng, G.Y.1
O'Dowd, B.F.2
Lee, S.P.3
Chung, H.T.4
Brann, M.R.5
Seeman, P.6
George, S.R.7
-
55
-
-
33644551294
-
Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers
-
Ciruela, F.; Casado, V.; Rodrigues, R.J.; Lujan, R.; Burgueno, J.; Canals, M.; Borycz, J.; Rebola, N.; Goldberg, S.R.; Mallol, J.; Cortes, A.; Canela, E.I.; Lopez-Gimenez, J.F.; Milligan, G.; Lluis, C.; Cunha, R.A.; Ferre, S.; Franco, R. Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. J. Neurosci., 2006, 26, 2080-2087.
-
(2006)
J. Neurosci
, vol.26
, pp. 2080-2087
-
-
Ciruela, F.1
Casado, V.2
Rodrigues, R.J.3
Lujan, R.4
Burgueno, J.5
Canals, M.6
Borycz, J.7
Rebola, N.8
Goldberg, S.R.9
Mallol, J.10
Cortes, A.11
Canela, E.I.12
Lopez-Gimenez, J.F.13
Milligan, G.14
Lluis, C.15
Cunha, R.A.16
Ferre, S.17
Franco, R.18
-
56
-
-
23944467820
-
D1 and D2 dopamine receptors form heterooligomers and cointernalize after selective activation of either receptor
-
So, C.H.; Varghese, G.; Curley, K.J.; Kong, M.M.; Alijaniaram, M.; Ji, X.; Nguyen, T.; O'Dowd B, F.; George, S.R. D1 and D2 dopamine receptors form heterooligomers and cointernalize after selective activation of either receptor. Mol. Pharmacol., 2005, 68, 568-578.
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 568-578
-
-
So, C.H.1
Varghese, G.2
Curley, K.J.3
Kong, M.M.4
Alijaniaram, M.5
Ji, X.6
Nguyen, T.7
O'Dowd, B.F.8
George, S.R.9
-
57
-
-
54449099573
-
Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum
-
Marcellino, D.; Ferre, S.; Casado, V.; Cortes, A.; Le Foll, B.; Mazzola, C.; Drago, F.; Saur, O.; Stark, H.; Soriano, A.; Barnes, C.; Goldberg, S.R.; Lluis, C.; Fuxe, K.; Franco, R. Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum. J. Biol. Chem., 2008, 283, 26016-26025.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 26016-26025
-
-
Marcellino, D.1
Ferre, S.2
Casado, V.3
Cortes, A.4
Le Foll, B.5
Mazzola, C.6
Drago, F.7
Saur, O.8
Stark, H.9
Soriano, A.10
Barnes, C.11
Goldberg, S.R.12
Lluis, C.13
Fuxe, K.14
Franco, R.15
-
58
-
-
45649085857
-
Reciprocal regulation of dopamine D1 and D3 receptor function and trafficking by heterodimerization
-
Fiorentini, C.; Busi, C.; Gorruso, E.; Gotti, C.; Spano, P.; Missale, C. Reciprocal regulation of dopamine D1 and D3 receptor function and trafficking by heterodimerization. Mol. Pharmacol., 2008, 74, 59-69.
-
(2008)
Mol. Pharmacol
, vol.74
, pp. 59-69
-
-
Fiorentini, C.1
Busi, C.2
Gorruso, E.3
Gotti, C.4
Spano, P.5
Missale, C.6
-
59
-
-
0142241355
-
Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole
-
Maggio, R.; Scarselli, M.; Novi, F.; Millan, M.J.; Corsini, G.U. Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole. J. Neurochem., 2003, 87, 631-641.
-
(2003)
J. Neurochem
, vol.87
, pp. 631-641
-
-
Maggio, R.1
Scarselli, M.2
Novi, F.3
Millan, M.J.4
Corsini, G.U.5
-
60
-
-
33646694071
-
The dopamine D3 receptor: A therapeutic target for the treatment of neuropsychiatric disorders
-
Sokoloff, P.; Diaz, J.; Le Foll, B.; Guillin, O.; Leriche, L.; Bezard, E.; Gross, C. The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders. CNS Neurol. Disord. Drug Targets, 2006, 5, 25-43.
-
(2006)
CNS Neurol. Disord. Drug Targets
, vol.5
, pp. 25-43
-
-
Sokoloff, P.1
Diaz, J.2
Le Foll, B.3
Guillin, O.4
Leriche, L.5
Bezard, E.6
Gross, C.7
-
61
-
-
0035839599
-
D2/D3 dopamine receptor heterodimers exhibit unique functional properties
-
Scarselli, M.; Novi, F.; Schallmach, E.; Lin, R.; Baragli, A.; Colzi, A.; Griffon, N.; Corsini, G.U.; Sokoloff, P.; Levenson, R.; Vogel, Z.; Maggio, R. D2/D3 dopamine receptor heterodimers exhibit unique functional properties. J. Biol. Chem., 2001, 276, 30308-30314.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 30308-30314
-
-
Scarselli, M.1
Novi, F.2
Schallmach, E.3
Lin, R.4
Baragli, A.5
Colzi, A.6
Griffon, N.7
Corsini, G.U.8
Sokoloff, P.9
Levenson, R.10
Vogel, Z.11
Maggio, R.12
-
62
-
-
0033806207
-
Evidence for adenosine/dopamine receptor interactions: Indications for heteromerization
-
Franco, R.; Ferre, S.; Agnati, L.; Torvinen, M.; Gines, S.; Hillion, J.; Casado, V.; Lledo, P.; Zoli, M.; Lluis, C.; Fuxe, K. Evidence for adenosine/dopamine receptor interactions: indications for heteromerization. Neuropsychopharmacology, 2000, 23, S50-S59.
-
(2000)
Neuropsychopharmacology
, vol.23
-
-
Franco, R.1
Ferre, S.2
Agnati, L.3
Torvinen, M.4
Gines, S.5
Hillion, J.6
Casado, V.7
Lledo, P.8
Zoli, M.9
Lluis, C.10
Fuxe, K.11
-
63
-
-
0037124032
-
Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors
-
Hillion, J.; Canals, M.; Torvinen, M.; Casado, V.; Scott, R.; Terasmaa, A.; Hansson, A.; Watson, S.; Olah, M.E.; Mallol, J.; Canela, E.I.; Zoli, M.; Agnati, L.F.; Ibanez, C.F.; Lluis, C.; Franco, R.; Ferre, S.; Fuxe, K. Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors. J. Biol. Chem., 2002, 277, 18091-18097.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 18091-18097
-
-
Hillion, J.1
Canals, M.2
Torvinen, M.3
Casado, V.4
Scott, R.5
Terasmaa, A.6
Hansson, A.7
Watson, S.8
Olah, M.E.9
Mallol, J.10
Canela, E.I.11
Zoli, M.12
Agnati, L.F.13
Ibanez, C.F.14
Lluis, C.15
Franco, R.16
Ferre, S.17
Fuxe, K.18
-
64
-
-
0037009163
-
Interactions among adenosine deaminase, adenosine A(1) receptors and dopamine D(1) receptors in stably cotransfected fibroblast cells and neurons
-
Torvinen, M.; Gines, S.; Hillion, J.; Latini, S.; Canals, M.; Ciruela, F.; Bordoni, F.; Staines, W.; Pedata, F.; Agnati, L.F.; Lluis, C.; Franco, R.; Ferre, S.; Fuxe, K. Interactions among adenosine deaminase, adenosine A(1) receptors and dopamine D(1) receptors in stably cotransfected fibroblast cells and neurons. Neuroscience, 2002, 113, 709-719.
-
(2002)
Neuroscience
, vol.113
, pp. 709-719
-
-
Torvinen, M.1
Gines, S.2
Hillion, J.3
Latini, S.4
Canals, M.5
Ciruela, F.6
Bordoni, F.7
Staines, W.8
Pedata, F.9
Agnati, L.F.10
Lluis, C.11
Franco, R.12
Ferre, S.13
Fuxe, K.14
-
65
-
-
12944279339
-
Biochemical identification of the dopamine D2 receptor domains interacting with the adenosine A2A receptor
-
Torvinen, M.; Kozell, L.B.; Neve, K.A.; Agnati, L.F.; Fuxe, K. Biochemical identification of the dopamine D2 receptor domains interacting with the adenosine A2A receptor. J. Mol. Neurosci., 2004, 24, 173-180.
-
(2004)
J. Mol. Neurosci
, vol.24
, pp. 173-180
-
-
Torvinen, M.1
Kozell, L.B.2
Neve, K.A.3
Agnati, L.F.4
Fuxe, K.5
-
66
-
-
0344875553
-
Adenosine A2A-dopamine D2 receptor-receptor heteromerization: Qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer
-
Canals, M.; Marcellino, D.; Fanelli, F.; Ciruela, F.; de Benedetti, P.; Goldberg, S.R.; Neve, K.; Fuxe, K.; Agnati, L.F.; Woods, A.S.; Ferre, S.; Lluis, C.; Bouvier, M.; Franco, R. Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J. Biol. Chem., 2003, 278, 46741-46749.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 46741-46749
-
-
Canals, M.1
Marcellino, D.2
Fanelli, F.3
Ciruela, F.4
de Benedetti, P.5
Goldberg, S.R.6
Neve, K.7
Fuxe, K.8
Agnati, L.F.9
Woods, A.S.10
Ferre, S.11
Lluis, C.12
Bouvier, M.13
Franco, R.14
-
67
-
-
0034682445
-
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes
-
Gines, S.; Hillion, J.; Torvinen, M.; Le Crom, S.; Casado, V.; Canela, E.I.; Rondin, S.; Lew, J.Y.; Watson, S.; Zoli, M.; Agnati, L.F.; Verniera, P.; Lluis, C.; Ferre, S.; Fuxe, K.; Franco, R. Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes. Proc. Natl. Acad. Sci. USA, 2000, 97, 8606-8611.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8606-8611
-
-
Gines, S.1
Hillion, J.2
Torvinen, M.3
Le Crom, S.4
Casado, V.5
Canela, E.I.6
Rondin, S.7
Lew, J.Y.8
Watson, S.9
Zoli, M.10
Agnati, L.F.11
Verniera, P.12
Lluis, C.13
Ferre, S.14
Fuxe, K.15
Franco, R.16
-
68
-
-
0032548504
-
Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells
-
Ferre, S.; Torvinen, M.; Antoniou, K.; Irenius, E.; Civelli, O.; Arenas, E.; Fredholm, B.B.; Fuxe, K. Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. J. Biol. Chem., 1998, 273, 4718-4724.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 4718-4724
-
-
Ferre, S.1
Torvinen, M.2
Antoniou, K.3
Irenius, E.4
Civelli, O.5
Arenas, E.6
Fredholm, B.B.7
Fuxe, K.8
-
69
-
-
33947528124
-
The enhancement of dopamine D1 receptor desensitization by adenosine A1 receptor activation
-
Cao, Y.; Xie, K.Q.; Zhu, X.Z. The enhancement of dopamine D1 receptor desensitization by adenosine A1 receptor activation. Eur. J. Pharmacol., 2007, 562, 34-38.
-
(2007)
Eur. J. Pharmacol
, vol.562
, pp. 34-38
-
-
Cao, Y.1
Xie, K.Q.2
Zhu, X.Z.3
-
70
-
-
0036734967
-
Autocrine activation of adenosine A1 receptors blocks D1A but not D1B dopamine receptor desensitization
-
Le Crom, S.; Prou, D.; Vernier, P. Autocrine activation of adenosine A1 receptors blocks D1A but not D1B dopamine receptor desensitization. J. Neurochem., 2002, 82, 1549-1552.
-
(2002)
J. Neurochem
, vol.82
, pp. 1549-1552
-
-
Le Crom, S.1
Prou, D.2
Vernier, P.3
-
71
-
-
33749065788
-
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum
-
Yabuuchi, K.; Kuroiwa, M.; Shuto, T.; Sotogaku, N.; Snyder, G.L.; Higashi, H.; Tanaka, M.; Greengard, P.; Nishi, A. Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum. Neuroscience, 2006, 141, 19-25.
-
(2006)
Neuroscience
, vol.141
, pp. 19-25
-
-
Yabuuchi, K.1
Kuroiwa, M.2
Shuto, T.3
Sotogaku, N.4
Snyder, G.L.5
Higashi, H.6
Tanaka, M.7
Greengard, P.8
Nishi, A.9
-
72
-
-
33748686166
-
Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells
-
Cao, Y.; Sun, W.C.; Jin, L.; Xie, K.Q.; Zhu, X.Z. Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells. Eur. J. Pharmacol., 2006, 548, 29-35.
-
(2006)
Eur. J. Pharmacol
, vol.548
, pp. 29-35
-
-
Cao, Y.1
Sun, W.C.2
Jin, L.3
Xie, K.Q.4
Zhu, X.Z.5
-
73
-
-
36949021554
-
Adenosine A1 receptor-mediated inhibition of dopamine release from rat striatal slices is modulated by D1 dopamine receptors
-
O'Neill, C.; Nolan, B.J.; Macari, A.; O'Boyle, K.M.; O'Connor, J.J. Adenosine A1 receptor-mediated inhibition of dopamine release from rat striatal slices is modulated by D1 dopamine receptors. Eur. J. Neurosci., 2007, 26, 3421-3428.
-
(2007)
Eur. J. Neurosci
, vol.26
, pp. 3421-3428
-
-
O'Neill, C.1
Nolan, B.J.2
Macari, A.3
O'Boyle, K.M.4
O'Connor, J.J.5
-
74
-
-
0028986566
-
Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia
-
Rivkees, S.A.; Price, S.L.; Zhou, F.C. Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia. Brain Res., 1995, 677, 193-203.
-
(1995)
Brain Res
, vol.677
, pp. 193-203
-
-
Rivkees, S.A.1
Price, S.L.2
Zhou, F.C.3
-
75
-
-
0030593688
-
Ultrastructural localization of D1 dopamine receptor immunoreactivity in rat striatonigral neurons and its relation with dopaminergic innervation
-
Caille, I.; Dumartin, B.; Bloch, B. Ultrastructural localization of D1 dopamine receptor immunoreactivity in rat striatonigral neurons and its relation with dopaminergic innervation. Brain Res., 1996, 730, 17-31.
-
(1996)
Brain Res
, vol.730
, pp. 17-31
-
-
Caille, I.1
Dumartin, B.2
Bloch, B.3
-
76
-
-
0025768754
-
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes
-
Ferre, S.; von Euler, G.; Johansson, B.; Fredholm, B.B.; Fuxe, K. Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proc. Natl. Acad. Sci. USA, 1991, 88, 7238-7241.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7238-7241
-
-
Ferre, S.1
von Euler, G.2
Johansson, B.3
Fredholm, B.B.4
Fuxe, K.5
-
77
-
-
0026437722
-
Dopamine denervation leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum
-
Ferre, S.; Fuxe, K. Dopamine denervation leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum. Brain Res., 1992, 594, 124-130.
-
(1992)
Brain Res
, vol.594
, pp. 124-130
-
-
Ferre, S.1
Fuxe, K.2
-
78
-
-
25844477182
-
Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function
-
Fuxe, K.; Ferre, S.; Canals, M.; Torvinen, M.; Terasmaa, A.; Marcellino, D.; Goldberg, S.R.; Staines, W.; Jacobsen, K.X.; Lluis, C.; Woods, A.S.; Agnati, L.F.; Franco, R. Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function. J. Mol. Neurosci., 2005, 26, 209-220.
-
(2005)
J. Mol. Neurosci
, vol.26
, pp. 209-220
-
-
Fuxe, K.1
Ferre, S.2
Canals, M.3
Torvinen, M.4
Terasmaa, A.5
Marcellino, D.6
Goldberg, S.R.7
Staines, W.8
Jacobsen, K.X.9
Lluis, C.10
Woods, A.S.11
Agnati, L.F.12
Franco, R.13
-
79
-
-
0037870163
-
Oligomerization of adenosine A2A and dopamine D2 receptors in living cells
-
Kamiya, T.; Saitoh, O.; Yoshioka, K.; Nakata, H. Oligomerization of adenosine A2A and dopamine D2 receptors in living cells. Biochem. Biophys. Res. Commun., 2003, 306, 544-549.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.306
, pp. 544-549
-
-
Kamiya, T.1
Saitoh, O.2
Yoshioka, K.3
Nakata, H.4
-
80
-
-
70350504371
-
Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors
-
Navarro, G.; Aymerich, M.S.; Marcellino, D.; Cortes, A.; Casado, V.; Mallol, J.; Canela, E.I.; Agnati, L.; Woods, A.S.; Fuxe, K.; Lluis, C.; Lanciego, J.L.; Ferre, S.; Franco, R. Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors. J. Biol. Chem., 2009, 284, 28058-28068.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 28058-28068
-
-
Navarro, G.1
Aymerich, M.S.2
Marcellino, D.3
Cortes, A.4
Casado, V.5
Mallol, J.6
Canela, E.I.7
Agnati, L.8
Woods, A.S.9
Fuxe, K.10
Lluis, C.11
Lanciego, J.L.12
Ferre, S.13
Franco, R.14
-
81
-
-
2942552330
-
Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders
-
Ferre, S.; Ciruela, F.; Canals, M.; Marcellino, D.; Burgueno, J.; Casado, V.; Hillion, J.; Torvinen, M.; Fanelli, F.; Benedetti Pd, P.; Goldberg, S.R.; Bouvier, M.; Fuxe, K.; Agnati, L.F.; Lluis, C.; Franco, R.; Woods, A. Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders. Parkinsonism Relat. Disord., 2004, 10, 265-271.
-
(2004)
Parkinsonism Relat. Disord
, vol.10
, pp. 265-271
-
-
Ferre, S.1
Ciruela, F.2
Canals, M.3
Marcellino, D.4
Burgueno, J.5
Casado, V.6
Hillion, J.7
Torvinen, M.8
Fanelli, F.9
Benedetti Pd, P.10
Goldberg, S.R.11
Bouvier, M.12
Fuxe, K.13
Agnati, L.F.14
Lluis, C.15
Franco, R.16
Woods, A.17
-
82
-
-
47349126631
-
An update on adenosine A2A-dopamine D2 receptor interactions: Implications for the function of G protein-coupled receptors
-
Ferre, S.; Quiroz, C.; Woods, A.S.; Cunha, R.; Popoli, P.; Ciruela, F.; Lluis, C.; Franco, R.; Azdad, K.; Schiffmann, S.N. An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors. Curr. Pharm. Des., 2008, 14, 1468-1474.
-
(2008)
Curr. Pharm. Des
, vol.14
, pp. 1468-1474
-
-
Ferre, S.1
Quiroz, C.2
Woods, A.S.3
Cunha, R.4
Popoli, P.5
Ciruela, F.6
Lluis, C.7
Franco, R.8
Azdad, K.9
Schiffmann, S.N.10
-
83
-
-
10744224952
-
Receptor heteromerization in adenosine A2A receptor signaling: Relevance for striatal function and Parkinson's disease
-
Fuxe, K.; Agnati, L.F.; Jacobsen, K.; Hillion, J.; Canals, M.; Torvinen, M.; Tinner-Staines, B.; Staines, W.; Rosin, D.; Terasmaa, A.; Popoli, P.; Leo, G.; Vergoni, V.; Lluis, C.; Ciruela, F.; Franco, R.; Ferre, S. Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology, 2003, 61, S19-S23.
-
(2003)
Neurology
, vol.61
-
-
Fuxe, K.1
Agnati, L.F.2
Jacobsen, K.3
Hillion, J.4
Canals, M.5
Torvinen, M.6
Tinner-Staines, B.7
Staines, W.8
Rosin, D.9
Terasmaa, A.10
Popoli, P.11
Leo, G.12
Vergoni, V.13
Lluis, C.14
Ciruela, F.15
Franco, R.16
Ferre, S.17
-
84
-
-
33947307050
-
Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal
-
Marcellino, D.; Roberts, D.C.; Navarro, G.; Filip, M.; Agnati, L.; Lluis, C.; Franco, R.; Fuxe, K. Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal. Brain Res., 2007, 1143, 208-220.
-
(2007)
Brain Res
, vol.1143
, pp. 208-220
-
-
Marcellino, D.1
Roberts, D.C.2
Navarro, G.3
Filip, M.4
Agnati, L.5
Lluis, C.6
Franco, R.7
Fuxe, K.8
-
85
-
-
0031594271
-
Adenosine A2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys
-
Kanda, T.; Jackson, M.J.; Smith, L.A.; Pearce, R.K.; Nakamura, J.; Kase, H.; Kuwana, Y.; Jenner, P. Adenosine A2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys. Ann. Neurol., 1998, 43, 507-513.
-
(1998)
Ann. Neurol
, vol.43
, pp. 507-513
-
-
Kanda, T.1
Jackson, M.J.2
Smith, L.A.3
Pearce, R.K.4
Nakamura, J.5
Kase, H.6
Kuwana, Y.7
Jenner, P.8
-
86
-
-
0035040326
-
Adenosine/dopamine interaction: Implications for the treatment of Parkinson's disease
-
Ferre, S.; Popoli, P.; Gimenez-Llort, L.; Rimondini, R.; Muller, C.E.; Stromberg, I.; Ogren, S.O.; Fuxe, K. Adenosine/dopamine interaction: implications for the treatment of Parkinson's disease. Parkinsonism Relat. Disord., 2001, 7, 235-241.
-
(2001)
Parkinsonism Relat. Disord
, vol.7
, pp. 235-241
-
-
Ferre, S.1
Popoli, P.2
Gimenez-Llort, L.3
Rimondini, R.4
Muller, C.E.5
Stromberg, I.6
Ogren, S.O.7
Fuxe, K.8
-
87
-
-
0030610581
-
Adenosine A2A agonists: A potential new type of atypical antipsychotic
-
Rimondini, R.; Ferre, S.; Ogren, S.O.; Fuxe, K. Adenosine A2A agonists: a potential new type of atypical antipsychotic. Neuropsychopharmacology, 1997, 17, 82-91.
-
(1997)
Neuropsychopharmacology
, vol.17
, pp. 82-91
-
-
Rimondini, R.1
Ferre, S.2
Ogren, S.O.3
Fuxe, K.4
-
88
-
-
0042626108
-
Adenosine A(2A) receptor antagonist treatment of Parkinson's disease
-
Bara-Jimenez, W.; Sherzai, A.; Dimitrova, T.; Favit, A.; Bibbiani, F.; Gillespie, M.; Morris, M.J.; Mouradian, M.M.; Chase, T.N. Adenosine A(2A) receptor antagonist treatment of Parkinson's disease. Neurology, 2003, 61, 293-296.
-
(2003)
Neurology
, vol.61
, pp. 293-296
-
-
Bara-Jimenez, W.1
Sherzai, A.2
Dimitrova, T.3
Favit, A.4
Bibbiani, F.5
Gillespie, M.6
Morris, M.J.7
Mouradian, M.M.8
Chase, T.N.9
-
89
-
-
26444445618
-
New therapies for the treatment of Parkinson's disease: Adenosine A2A receptor antagonists
-
Pinna, A.; Wardas, J.; Simola, N.; Morelli, M. New therapies for the treatment of Parkinson's disease: adenosine A2A receptor antagonists. Life Sci., 2005, 77, 3259-3267.
-
(2005)
Life Sci
, vol.77
, pp. 3259-3267
-
-
Pinna, A.1
Wardas, J.2
Simola, N.3
Morelli, M.4
-
90
-
-
47349112609
-
Adenosine A2A receptor antagonists and Parkinson's disease: State of the art and future directions
-
Simola, N.; Morelli, M.; Pinna, A. Adenosine A2A receptor antagonists and Parkinson's disease: state of the art and future directions. Curr. Pharm. Des., 2008, 14, 1475-1489.
-
(2008)
Curr. Pharm. Des
, vol.14
, pp. 1475-1489
-
-
Simola, N.1
Morelli, M.2
Pinna, A.3
-
91
-
-
70450219517
-
Inactivation of neuronal forebrain A(2A) receptors protects dopaminergic neurons in a mouse model of Parkinson's disease
-
Carta, A.R.; Kachroo, A.; Schintu, N.; Xu, K.; Schwarzschild, M.A.; Wardas, J.; Morelli, M. Inactivation of neuronal forebrain A(2A) receptors protects dopaminergic neurons in a mouse model of Parkinson's disease. J. Neurochem., 2009, 111(6), 1478-1489.
-
(2009)
J. Neurochem
, vol.111
, Issue.6
, pp. 1478-1489
-
-
Carta, A.R.1
Kachroo, A.2
Schintu, N.3
Xu, K.4
Schwarzschild, M.A.5
Wardas, J.6
Morelli, M.7
-
92
-
-
0027948322
-
Antagonistic interaction between adenosine A2A receptors and dopamine D2 receptors in the ventral striopallidal system. Implications for the treatment of schizophrenia
-
Ferre, S.; O'Connor, W.T.; Snaprud, P.; Ungerstedt, U.; Fuxe, K. Antagonistic interaction between adenosine A2A receptors and dopamine D2 receptors in the ventral striopallidal system. Implications for the treatment of schizophrenia. Neuroscience, 1994, 63, 765-773.
-
(1994)
Neuroscience
, vol.63
, pp. 765-773
-
-
Ferre, S.1
O'Connor, W.T.2
Snaprud, P.3
Ungerstedt, U.4
Fuxe, K.5
-
93
-
-
0034069595
-
Dipyridamole in the treatment of schizophrenia: Adenosine-dopamine receptor interactions
-
Akhondzadeh, S.; Shasavand, E.; Jamilian, H.; Shabestari, O.; Kamalipour, A. Dipyridamole in the treatment of schizophrenia: adenosine-dopamine receptor interactions. J. Clin. Pharm. Ther., 2000, 25, 131-137.
-
(2000)
J. Clin. Pharm. Ther
, vol.25
, pp. 131-137
-
-
Akhondzadeh, S.1
Shasavand, E.2
Jamilian, H.3
Shabestari, O.4
Kamalipour, A.5
-
94
-
-
0037015027
-
Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: Implications for striatal neuronal function
-
Ferre, S.; Karcz-Kubicha, M.; Hope, B.T.; Popoli, P.; Burgueno, J.; Gutierrez, M.A.; Casado, V.; Fuxe, K.; Goldberg, S.R.; Lluis, C.; Franco, R.; Ciruela, F. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc. Natl. Acad. Sci. USA, 2002, 99, 11940-11945.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11940-11945
-
-
Ferre, S.1
Karcz-Kubicha, M.2
Hope, B.T.3
Popoli, P.4
Burgueno, J.5
Gutierrez, M.A.6
Casado, V.7
Fuxe, K.8
Goldberg, S.R.9
Lluis, C.10
Franco, R.11
Ciruela, F.12
-
95
-
-
4444382866
-
Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum
-
Domenici, M.R.; Pepponi, R.; Martire, A.; Tebano, M.T.; Potenza, R.L.; Popoli, P. Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum. J. Neurochem., 2004, 90, 1276-1279.
-
(2004)
J. Neurochem
, vol.90
, pp. 1276-1279
-
-
Domenici, M.R.1
Pepponi, R.2
Martire, A.3
Tebano, M.T.4
Potenza, R.L.5
Popoli, P.6
-
96
-
-
13244264871
-
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
-
Rodrigues, R.J.; Alfaro, T.M.; Rebola, N.; Oliveira, C.R.; Cunha, R.A. Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. J. Neurochem., 2005, 92, 433-441.
-
(2005)
J. Neurochem
, vol.92
, pp. 433-441
-
-
Rodrigues, R.J.1
Alfaro, T.M.2
Rebola, N.3
Oliveira, C.R.4
Cunha, R.A.5
-
97
-
-
0032587703
-
Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum
-
Ferre, S.; Popoli, P.; Rimondini, R.; Reggio, R.; Kehr, J.; Fuxe, K. Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum. Neuropharmacology, 1999, 38, 129-140.
-
(1999)
Neuropharmacology
, vol.38
, pp. 129-140
-
-
Ferre, S.1
Popoli, P.2
Rimondini, R.3
Reggio, R.4
Kehr, J.5
Fuxe, K.6
-
98
-
-
0034856088
-
The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: Interactions with adenosine A(2a) receptors
-
Popoli, P.; Pezzola, A.; Torvinen, M.; Reggio, R.; Pintor, A.; Scarchilli, L.; Fuxe, K.; Ferre, S. The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: interactions with adenosine A(2a) receptors. Neuropsychopharmacology, 2001, 25, 505-513.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 505-513
-
-
Popoli, P.1
Pezzola, A.2
Torvinen, M.3
Reggio, R.4
Pintor, A.5
Scarchilli, L.6
Fuxe, K.7
Ferre, S.8
-
99
-
-
0037123728
-
Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors
-
Diaz-Cabiale, Z.; Vivo, M.; Del Arco, A.; O'Connor, W.T.; Harte, M.K.; Muller, C.E.; Martinez, E.; Popoli, P.; Fuxe, K.; Ferre, S. Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors. Neurosci. Lett., 2002, 324, 154-158.
-
(2002)
Neurosci. Lett
, vol.324
, pp. 154-158
-
-
Diaz-Cabiale, Z.1
Vivo, M.2
Del Arco, A.3
O'Connor, W.T.4
Harte, M.K.5
Muller, C.E.6
Martinez, E.7
Popoli, P.8
Fuxe, K.9
Ferre, S.10
-
100
-
-
3242765264
-
Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats
-
Coccurello, R.; Breysse, N.; Amalric, M. Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats. Neuropsychopharmacology, 2004, 29, 1451-1461.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1451-1461
-
-
Coccurello, R.1
Breysse, N.2
Amalric, M.3
-
101
-
-
27744450594
-
Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice
-
Kachroo, A.; Orlando, L.R.; Grandy, D.K.; Chen, J.F.; Young, A.B.; Schwarzschild, M.A. Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. J. Neurosci., 2005, 25, 10414-10419.
-
(2005)
J. Neurosci
, vol.25
, pp. 10414-10419
-
-
Kachroo, A.1
Orlando, L.R.2
Grandy, D.K.3
Chen, J.F.4
Young, A.B.5
Schwarzschild, M.A.6
-
102
-
-
65549160499
-
Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cells
-
Cabello, N.; Gandia, J.; Bertarelli, D.C.; Watanabe, M.; Lluis, C.; Franco, R.; Ferre, S.; Lujan, R.; Ciruela, F. Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cells. J. Neurochem., 2009, 109, 1497-1507.
-
(2009)
J. Neurochem
, vol.109
, pp. 1497-1507
-
-
Cabello, N.1
Gandia, J.2
Bertarelli, D.C.3
Watanabe, M.4
Lluis, C.5
Franco, R.6
Ferre, S.7
Lujan, R.8
Ciruela, F.9
-
103
-
-
0037417810
-
Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling
-
Nishi, A.; Liu, F.; Matsuyama, S.; Hamada, M.; Higashi, H.; Nairn, A.C.; Greengard, P. Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling. Proc. Natl. Acad. Sci. USA, 2003, 100, 1322-1327.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1322-1327
-
-
Nishi, A.1
Liu, F.2
Matsuyama, S.3
Hamada, M.4
Higashi, H.5
Nairn, A.C.6
Greengard, P.7
-
104
-
-
0037273830
-
Glutamate receptors and Parkinson's disease: Opportunities for intervention
-
Marino, M.J.; Valenti, O.; Conn, P.J. Glutamate receptors and Parkinson's disease: opportunities for intervention. Drugs Aging, 2003, 20, 377-397.
-
(2003)
Drugs Aging
, vol.20
, pp. 377-397
-
-
Marino, M.J.1
Valenti, O.2
Conn, P.J.3
-
105
-
-
14544288232
-
Therapeutic potential of adenosine A(2A) receptor antagonists in Parkinson's disease
-
Xu, K.; Bastia, E.; Schwarzschild, M. Therapeutic potential of adenosine A(2A) receptor antagonists in Parkinson's disease. Pharmacol. Ther., 2005, 105, 267-310.
-
(2005)
Pharmacol. Ther
, vol.105
, pp. 267-310
-
-
Xu, K.1
Bastia, E.2
Schwarzschild, M.3
-
106
-
-
38949186761
-
Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats
-
Adams, C.L.; Cowen, M.S.; Short, J.L.; Lawrence, A.J. Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats. Int. J. Neuropsychopharmacol., 2008, 11, 229-241.
-
(2008)
Int. J. Neuropsychopharmacol
, vol.11
, pp. 229-241
-
-
Adams, C.L.1
Cowen, M.S.2
Short, J.L.3
Lawrence, A.J.4
-
107
-
-
33144488036
-
Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens
-
Pickel, V.M.; Chan, J.; Kearn, C.S.; Mackie, K. Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens. J. Comp. Neurol., 2006, 495, 299-313.
-
(2006)
J. Comp. Neurol
, vol.495
, pp. 299-313
-
-
Pickel, V.M.1
Chan, J.2
Kearn, C.S.3
Mackie, K.4
-
108
-
-
33744490080
-
Frequency-specific and D2 receptor-mediated inhibition of glutamate release by retrograde endocannabinoid signaling
-
Yin, H.H.; Lovinger, D.M. Frequency-specific and D2 receptor-mediated inhibition of glutamate release by retrograde endocannabinoid signaling. Proc. Natl. Acad. Sci. USA, 2006, 103, 8251-8256.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8251-8256
-
-
Yin, H.H.1
Lovinger, D.M.2
-
109
-
-
0038663171
-
Neuroanatomical relationship between type 1 cannabinoid receptors and dopaminergic systems in the rat basal ganglia
-
Julian, M.D.; Martin, A.B.; Cuellar, B.; Rodriguez De Fonseca, F.; Navarro, M.; Moratalla, R.; Garcia-Segura, L.M. Neuroanatomical relationship between type 1 cannabinoid receptors and dopaminergic systems in the rat basal ganglia. Neuroscience, 2003, 119, 309-318.
-
(2003)
Neuroscience
, vol.119
, pp. 309-318
-
-
Julian, M.D.1
Martin, A.B.2
Cuellar, B.3
Rodriguez De Fonseca, F.4
Navarro, M.5
Moratalla, R.6
Garcia-Segura, L.M.7
-
110
-
-
3242810641
-
Immunolocalization of CB1 receptor in rat striatal neurons: A confocal microscopy study
-
Fusco, F.R.; Martorana, A.; Giampa, C.; De March, Z.; Farini, D.; D'Angelo, V.; Sancesario, G.; Bernardi, G. Immunolocalization of CB1 receptor in rat striatal neurons: a confocal microscopy study. Synapse, 2004, 53, 159-167.
-
(2004)
Synapse
, vol.53
, pp. 159-167
-
-
Fusco, F.R.1
Martorana, A.2
Giampa, C.3
de March, Z.4
Farini, D.5
D'Angelo, V.6
Sancesario, G.7
Bernardi, G.8
-
111
-
-
15244356828
-
Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: A combined immunochemical and pharmacological analysis
-
Kofalvi, A.; Rodrigues, R.J.; Ledent, C.; Mackie, K.; Vizi, E.S.; Cunha, R.A.; Sperlagh, B. Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis. J. Neurosci., 2005, 25, 2874-2884.
-
(2005)
J. Neurosci
, vol.25
, pp. 2874-2884
-
-
Kofalvi, A.1
Rodrigues, R.J.2
Ledent, C.3
Mackie, K.4
Vizi, E.S.5
Cunha, R.A.6
Sperlagh, B.7
-
112
-
-
29744460503
-
Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia
-
Matyas, F.; Yanovsky, Y.; Mackie, K.; Kelsch, W.; Misgeld, U.; Freund, T.F. Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia. Neuroscience, 2006, 137, 337-361.
-
(2006)
Neuroscience
, vol.137
, pp. 337-361
-
-
Matyas, F.1
Yanovsky, Y.2
Mackie, K.3
Kelsch, W.4
Misgeld, U.5
Freund, T.F.6
-
113
-
-
69949139695
-
Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum
-
Tebano, M.T.; Martire, A.; Chiodi, V.; Pepponi, R.; Ferrante, A.; Domenici, M.R.; Frank, C.; Chen, J.F.; Ledent, C.; Popoli, P. Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum. J. Neurochem., 2009, 110, 1921-1930.
-
(2009)
J. Neurochem
, vol.110
, pp. 1921-1930
-
-
Tebano, M.T.1
Martire, A.2
Chiodi, V.3
Pepponi, R.4
Ferrante, A.5
Domenici, M.R.6
Frank, C.7
Chen, J.F.8
Ledent, C.9
Popoli, P.10
-
114
-
-
34548538764
-
Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids
-
Carriba, P.; Ortiz, O.; Patkar, K.; Justinova, Z.; Stroik, J.; Themann, A.; Muller, C.; Woods, A.S.; Hope, B.T.; Ciruela, F.; Casado, V.; Canela, E.I.; Lluis, C.; Goldberg, S.R.; Moratalla, R.; Franco, R.; Ferre, S. Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids. Neuropsychopharmacology, 2007, 32, 2249-2259.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 2249-2259
-
-
Carriba, P.1
Ortiz, O.2
Patkar, K.3
Justinova, Z.4
Stroik, J.5
Themann, A.6
Muller, C.7
Woods, A.S.8
Hope, B.T.9
Ciruela, F.10
Casado, V.11
Canela, E.I.12
Lluis, C.13
Goldberg, S.R.14
Moratalla, R.15
Franco, R.16
Ferre, S.17
-
115
-
-
4944240410
-
Adenosine A2A receptors are involved in physical dependence and place conditioning induced by THC
-
Soria, G.; Castane, A.; Berrendero, F.; Ledent, C.; Parmentier, M.; Maldonado, R.; Valverde, O. Adenosine A2A receptors are involved in physical dependence and place conditioning induced by THC. Eur. J. Neurosci., 2004, 20, 2203-2213.
-
(2004)
Eur. J. Neurosci
, vol.20
, pp. 2203-2213
-
-
Soria, G.1
Castane, A.2
Berrendero, F.3
Ledent, C.4
Parmentier, M.5
Maldonado, R.6
Valverde, O.7
-
116
-
-
0034981628
-
Signal transduction interactions between CB1 cannabinoid and dopamine receptors in the rat and monkey striatum
-
Meschler, J.P.; Howlett, A.C. Signal transduction interactions between CB1 cannabinoid and dopamine receptors in the rat and monkey striatum. Neuropharmacology, 2001, 40, 918-926.
-
(2001)
Neuropharmacology
, vol.40
, pp. 918-926
-
-
Meschler, J.P.1
Howlett, A.C.2
-
117
-
-
1342344556
-
D2 dopamine receptors modulate Galpha-subunit coupling of the CB1 cannabinoid receptor
-
Jarrahian, A.; Watts, V.J.; Barker, E.L. D2 dopamine receptors modulate Galpha-subunit coupling of the CB1 cannabinoid receptor. J. Pharmacol. Exp. Ther., 2004, 308, 880-886.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.308
, pp. 880-886
-
-
Jarrahian, A.1
Watts, V.J.2
Barker, E.L.3
-
118
-
-
43649097012
-
Expression and function of CB1 receptor in the rat striatum: Localization and effects on D1 and D2 dopamine receptor-mediated motor behaviors
-
Martin, A.B.; Fernandez-Espejo, E.; Ferrer, B.; Gorriti, M.A.; Bilbao, A.; Navarro, M.; Rodriguez de Fonseca, F.; Moratalla, R. Expression and function of CB1 receptor in the rat striatum: localization and effects on D1 and D2 dopamine receptor-mediated motor behaviors. Neuropsychopharmacology, 2008, 33, 1667-1679.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 1667-1679
-
-
Martin, A.B.1
Fernandez-Espejo, E.2
Ferrer, B.3
Gorriti, M.A.4
Bilbao, A.5
Navarro, M.6
Rodriguez de Fonseca, F.7
Moratalla, R.8
-
119
-
-
0036166628
-
Involvement of CB1 cannabinoid receptors in emotional behaviour
-
Martin, M.; Ledent, C.; Parmentier, M.; Maldonado, R.; Valverde, O. Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology (Berl.), 2002, 159, 379-387.
-
(2002)
Psychopharmacology (Berl.)
, vol.159
, pp. 379-387
-
-
Martin, M.1
Ledent, C.2
Parmentier, M.3
Maldonado, R.4
Valverde, O.5
-
120
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent, C.; Valverde, O.; Cossu, G.; Petitet, F.; Aubert, J.F.; Beslot, F.; Bohme, G.A.; Imperato, A.; Pedrazzini, T.; Roques, B.P.; Vassart, G.; Fratta, W.; Parmentier, M. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science, 1999, 283, 401-404.
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
Petitet, F.4
Aubert, J.F.5
Beslot, F.6
Bohme, G.A.7
Imperato, A.8
Pedrazzini, T.9
Roques, B.P.10
Vassart, G.11
Fratta, W.12
Parmentier, M.13
-
121
-
-
33646751913
-
Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats
-
Yao, L.; McFarland, K.; Fan, P.; Jiang, Z.; Ueda, T.; Diamond, I. Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats. Proc. Natl. Acad. Sci. USA, 2006, 103, 7877-7882.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7877-7882
-
-
Yao, L.1
McFarland, K.2
Fan, P.3
Jiang, Z.4
Ueda, T.5
Diamond, I.6
-
122
-
-
45349087157
-
Pharmacological activation of CB1 and D2 receptors in rats: Predominant role of CB1 in the increase of alcohol relapse
-
Alen, F.; Moreno-Sanz, G.; Isabel de Tena, A.; Brooks, R.D.; Lopez-Jimenez, A.; Navarro, M.; Lopez-Moreno, J.A. Pharmacological activation of CB1 and D2 receptors in rats: predominant role of CB1 in the increase of alcohol relapse. Eur. J. Neurosci., 2008, 27, 3292-3298.
-
(2008)
Eur. J. Neurosci
, vol.27
, pp. 3292-3298
-
-
Alen, F.1
Moreno-Sanz, G.2
Isabel de Tena, A.3
Brooks, R.D.4
Lopez-Jimenez, A.5
Navarro, M.6
Lopez-Moreno, J.A.7
-
123
-
-
61349156089
-
Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB(1)-dopamine D(2) receptor mechanism
-
[Epub ahead of print]
-
Rasmussen, B.A.; Kim, E.; Unterwald, E.M.; Rawls, S.M. Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB(1)-dopamine D(2) receptor mechanism. Brain Res., 2009, [Epub ahead of print].
-
(2009)
Brain Res
-
-
Rasmussen, B.A.1
Kim, E.2
Unterwald, E.M.3
Rawls, S.M.4
-
124
-
-
17844410926
-
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: A mechanism for receptor cross-talk?
-
Kearn, C.S.; Blake-Palmer, K.; Daniel, E.; Mackie, K.; Glass, M. Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? Mol. Pharmacol., 2005, 67, 1697-1704.
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 1697-1704
-
-
Kearn, C.S.1
Blake-Palmer, K.2
Daniel, E.3
Mackie, K.4
Glass, M.5
-
125
-
-
40849137554
-
Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis
-
Marcellino, D.; Carriba, P.; Filip, M.; Borgkvist, A.; Frankowska, M.; Bellido, I.; Tanganelli, S.; Muller, C.E.; Fisone, G.; Lluis, C.; Agnati, L.F.; Franco, R.; Fuxe, K. Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis. Neuropharmacology, 2008, 54, 815-823.
-
(2008)
Neuropharmacology
, vol.54
, pp. 815-823
-
-
Marcellino, D.1
Carriba, P.2
Filip, M.3
Borgkvist, A.4
Frankowska, M.5
Bellido, I.6
Tanganelli, S.7
Muller, C.E.8
Fisone, G.9
Lluis, C.10
Agnati, L.F.11
Franco, R.12
Fuxe, K.13
-
126
-
-
58149096475
-
Looking for the role of cannabinoid receptor heteromers in striatal function
-
Suppl
-
Ferre, S.; Goldberg, S.R.; Lluis, C.; Franco, R. Looking for the role of cannabinoid receptor heteromers in striatal function. Neuropharmacology, 2009, 56(Suppl 1), 226-234.
-
(2009)
Neuropharmacology
, vol.56
, Issue.1
, pp. 226-234
-
-
Ferre, S.1
Goldberg, S.R.2
Lluis, C.3
Franco, R.4
-
127
-
-
55549147195
-
Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer
-
Navarro, G.; Carriba, P.; Gandia, J.; Ciruela, F.; Casado, V.; Cortes, A.; Mallol, J.; Canela, E.I.; Lluis, C.; Franco, R. Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer. Sci. World J., 2008, 8, 1088-1097.
-
(2008)
Sci. World J
, vol.8
, pp. 1088-1097
-
-
Navarro, G.1
Carriba, P.2
Gandia, J.3
Ciruela, F.4
Casado, V.5
Cortes, A.6
Mallol, J.7
Canela, E.I.8
Lluis, C.9
Franco, R.10
-
128
-
-
48449100036
-
Detection of heteromerization of more than two proteins by sequential BRET-FRET
-
Carriba, P.; Navarro, G.; Ciruela, F.; Ferre, S.; Casado, V.; Agnati, L.; Cortes, A.; Mallol, J.; Fuxe, K.; Canela, E.I.; Lluis, C.; Franco, R. Detection of heteromerization of more than two proteins by sequential BRET-FRET. Nat. Methods, 2008, 5, 727-733.
-
(2008)
Nat. Methods
, vol.5
, pp. 727-733
-
-
Carriba, P.1
Navarro, G.2
Ciruela, F.3
Ferre, S.4
Casado, V.5
Agnati, L.6
Cortes, A.7
Mallol, J.8
Fuxe, K.9
Canela, E.I.10
Lluis, C.11
Franco, R.12
-
129
-
-
37249010179
-
Bimolecular fluorescence complementation: Visualization of molecular interactions in living cells
-
Kerppola, T.K. Bimolecular fluorescence complementation: visualization of molecular interactions in living cells. Methods Cell Biol., 2008, 85, 431-470.
-
(2008)
Methods Cell Biol
, vol.85
, pp. 431-470
-
-
Kerppola, T.K.1
-
130
-
-
0037416297
-
Up-regulation of striatal adenosine A(2A) receptors in schizophrenia
-
Deckert, J.; Brenner, M.; Durany, N.; Zochling, R.; Paulus, W.; Ransmayr, G.; Tatschner, T.; Danielczyk, W.; Jellinger, K.; Riederer, P. Up-regulation of striatal adenosine A(2A) receptors in schizophrenia. Neuroreport, 2003, 14, 313-316.
-
(2003)
Neuroreport
, vol.14
, pp. 313-316
-
-
Deckert, J.1
Brenner, M.2
Durany, N.3
Zochling, R.4
Paulus, W.5
Ransmayr, G.6
Tatschner, T.7
Danielczyk, W.8
Jellinger, K.9
Riederer, P.10
-
131
-
-
33847409606
-
Neurobiology of dopamine in schizophrenia
-
Guillin, O.; Abi-Dargham, A.; Laruelle, M. Neurobiology of dopamine in schizophrenia. Int. Rev. Neurobiol., 2007, 78, 1-39.
-
(2007)
Int. Rev. Neurobiol
, vol.78
, pp. 1-39
-
-
Guillin, O.1
Abi-Dargham, A.2
Laruelle, M.3
-
132
-
-
0035961131
-
Studies on [3H]CP-55940 binding in the human central nervous system: Regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use
-
Dean, B.; Sundram, S.; Bradbury, R.; Scarr, E.; Copolov, D. Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience, 2001, 103, 9-15.
-
(2001)
Neuroscience
, vol.103
, pp. 9-15
-
-
Dean, B.1
Sundram, S.2
Bradbury, R.3
Scarr, E.4
Copolov, D.5
-
133
-
-
23944440689
-
Clozapine decreases [3H] CP 55940 binding to the cannabinoid 1 receptor in the rat nucleus accumbens
-
Sundram, S.; Copolov, D.; Dean, B. Clozapine decreases [3H] CP 55940 binding to the cannabinoid 1 receptor in the rat nucleus accumbens. Naunyn Schmiedebergs Arch. Pharmacol., 2005, 371, 428-433.
-
(2005)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.371
, pp. 428-433
-
-
Sundram, S.1
Copolov, D.2
Dean, B.3
-
134
-
-
69549105668
-
Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: Effect of antipsychotic treatment
-
Uriguen, L.; Garcia-Fuster, M.J.; Callado, L.F.; Morentin, B.; La Harpe, R.; Casado, V.; Lluis, C.; Franco, R.; Garcia-Sevilla, J.A.; Meana, J.J. Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatment. Psychopharmacology (Berl.), 2009, 206, 313-324.
-
(2009)
Psychopharmacology (Berl.)
, vol.206
, pp. 313-324
-
-
Uriguen, L.1
Garcia-Fuster, M.J.2
Callado, L.F.3
Morentin, B.4
la Harpe, R.5
Casado, V.6
Lluis, C.7
Franco, R.8
Garcia-Sevilla, J.A.9
Meana, J.J.10
-
135
-
-
44849104847
-
Serotonin receptors
-
Nichols, D.E.; Nichols, C.D. Serotonin receptors. Chem. Rev., 2008, 108, 1614-1641.
-
(2008)
Chem. Rev
, vol.108
, pp. 1614-1641
-
-
Nichols, D.E.1
Nichols, C.D.2
-
136
-
-
40449139964
-
Identification of a serotonin/glutamate receptor complex implicated in psychosis
-
Gonzalez-Maeso, J.; Ang, R.L.; Yuen, T.; Chan, P.; Weisstaub, N.V.; Lopez-Gimenez, J.F.; Zhou, M.; Okawa, Y.; Callado, L.F.; Milligan, G.; Gingrich, J.A.; Filizola, M.; Meana, J.J.; Sealfon, S.C. Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature, 2008, 452, 93-97.
-
(2008)
Nature
, vol.452
, pp. 93-97
-
-
Gonzalez-Maeso, J.1
Ang, R.L.2
Yuen, T.3
Chan, P.4
Weisstaub, N.V.5
Lopez-Gimenez, J.F.6
Zhou, M.7
Okawa, Y.8
Callado, L.F.9
Milligan, G.10
Gingrich, J.A.11
Filizola, M.12
Meana, J.J.13
Sealfon, S.C.14
-
138
-
-
65649143515
-
Agonist-trafficking and hallucinogens
-
Gonzalez-Maeso, J.; Sealfon, S.C. Agonist-trafficking and hallucinogens. Curr. Med. Chem., 2009, 16, 1017-1027.
-
(2009)
Curr. Med. Chem
, vol.16
, pp. 1017-1027
-
-
Gonzalez-Maeso, J.1
Sealfon, S.C.2
-
139
-
-
70849108405
-
Group II metabotropic glutamate receptors and schizophrenia
-
Moreno, J.L.; Sealfon, S.C.; Gonzalez-Maeso, J. Group II metabotropic glutamate receptors and schizophrenia. Cell Mol. Life Sci., 2009, 66, 3777-3785.
-
(2009)
Cell Mol. Life Sci
, vol.66
, pp. 3777-3785
-
-
Moreno, J.L.1
Sealfon, S.C.2
Gonzalez-Maeso, J.3
-
141
-
-
0141753077
-
Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex
-
Gonzalez-Maeso, J.; Yuen, T.; Ebersole, B.J.; Wurmbach, E.; Lira, A.; Zhou, M.; Weisstaub, N.; Hen, R.; Gingrich, J.A.; Sealfon, S.C. Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. J. Neurosci., 2003, 23, 8836-8843.
-
(2003)
J. Neurosci
, vol.23
, pp. 8836-8843
-
-
Gonzalez-Maeso, J.1
Yuen, T.2
Ebersole, B.J.3
Wurmbach, E.4
Lira, A.5
Zhou, M.6
Weisstaub, N.7
Hen, R.8
Gingrich, J.A.9
Sealfon, S.C.10
-
142
-
-
33846549510
-
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior
-
Gonzalez-Maeso, J.; Weisstaub, N.V.; Zhou, M.; Chan, P.; Ivic, L.; Ang, R.; Lira, A.; Bradley-Moore, M.; Ge, Y.; Zhou, Q.; Sealfon, S.C.; Gingrich, J.A. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron, 2007, 53, 439-452.
-
(2007)
Neuron
, vol.53
, pp. 439-452
-
-
Gonzalez-Maeso, J.1
Weisstaub, N.V.2
Zhou, M.3
Chan, P.4
Ivic, L.5
Ang, R.6
Lira, A.7
Bradley-Moore, M.8
Ge, Y.9
Zhou, Q.10
Sealfon, S.C.11
Gingrich, J.A.12
-
143
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
Patil, S.T.; Zhang, L.; Martenyi, F.; Lowe, S.L.; Jackson, K.A.; Andreev, B.V.; Avedisova, A.S.; Bardenstein, L.M.; Gurovich, I.Y.; Morozova, M.A.; Mosolov, S.N.; Neznanov, N.G.; Reznik, A.M.; Smulevich, A.B.; Tochilov, V.A.; Johnson, B.G.; Monn, J.A.; Schoepp, D.D. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat. Med., 2007, 13, 1102-1107.
-
(2007)
Nat. Med
, vol.13
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
Andreev, B.V.6
Avedisova, A.S.7
Bardenstein, L.M.8
Gurovich, I.Y.9
Morozova, M.A.10
Mosolov, S.N.11
Neznanov, N.G.12
Reznik, A.M.13
Smulevich, A.B.14
Tochilov, V.A.15
Johnson, B.G.16
Monn, J.A.17
Schoepp, D.D.18
-
144
-
-
0034055690
-
Serotonin model of schizophrenia: Emerging role of glutamate mechanisms
-
Aghajanian, G.K.; Marek, G.J. Serotonin model of schizophrenia: emerging role of glutamate mechanisms. Brain Res. Brain Res. Rev., 2000, 31, 302-312.
-
(2000)
Brain Res. Brain Res. Rev
, vol.31
, pp. 302-312
-
-
Aghajanian, G.K.1
Marek, G.J.2
-
145
-
-
0742323781
-
Metabotropic glutamate 2/3 receptors as drug targets
-
Marek, G.J. Metabotropic glutamate 2/3 receptors as drug targets. Curr. Opin. Pharmacol., 2004, 4, 18-22.
-
(2004)
Curr. Opin. Pharmacol
, vol.4
, pp. 18-22
-
-
Marek, G.J.1
-
146
-
-
0019361586
-
Clonidine activates membrane potassium conductance in myenteric neurones
-
Morita, K.; North, R.A. Clonidine activates membrane potassium conductance in myenteric neurones. Br. J. Pharmacol., 1981, 74, 419-428.
-
(1981)
Br. J. Pharmacol
, vol.74
, pp. 419-428
-
-
Morita, K.1
North, R.A.2
-
147
-
-
0031978653
-
Alpha 2-adrenergic receptors increase cell migration and decrease F-actin labeling in rat aortic smooth muscle cells
-
Richman, J.G.; Regan, J.W. Alpha 2-adrenergic receptors increase cell migration and decrease F-actin labeling in rat aortic smooth muscle cells. Am. J. Physiol., 1998, 274, C654-662.
-
(1998)
Am. J. Physiol
, vol.274
-
-
Richman, J.G.1
Regan, J.W.2
-
148
-
-
0031874288
-
Molecular mechanisms of opioid receptor signal transduction
-
Jordan, B.; Devi, L.A. Molecular mechanisms of opioid receptor signal transduction. Br. J. Anaesth., 1998, 81, 12-19.
-
(1998)
Br. J. Anaesth
, vol.81
, pp. 12-19
-
-
Jordan, B.1
Devi, L.A.2
-
149
-
-
0018130198
-
Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture
-
Macdonald, R.L.; Nelson, P.G. Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture. Science, 1978, 199, 1449-1451.
-
(1978)
Science
, vol.199
, pp. 1449-1451
-
-
Macdonald, R.L.1
Nelson, P.G.2
-
150
-
-
0030611098
-
The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy
-
Stone, L.S.; MacMillan, L.B.; Kitto, K.F.; Limbird, L.E.; Wilcox, G.L. The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy. J. Neurosci., 1997, 17, 7157-7165.
-
(1997)
J. Neurosci
, vol.17
, pp. 7157-7165
-
-
Stone, L.S.1
Macmillan, L.B.2
Kitto, K.F.3
Limbird, L.E.4
Wilcox, G.L.5
-
151
-
-
0023176530
-
Central and systemic morphine-induced antinociception in mice: Contribution of descending serotonergic and noradrenergic pathways
-
Wigdor, S.; Wilcox, G.L. Central and systemic morphine-induced antinociception in mice: contribution of descending serotonergic and noradrenergic pathways. J. Pharmacol. Exp. Ther., 1987, 242, 90-95.
-
(1987)
J. Pharmacol. Exp. Ther
, vol.242
, pp. 90-95
-
-
Wigdor, S.1
Wilcox, G.L.2
-
152
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
Matthes, H.W.; Maldonado, R.; Simonin, F.; Valverde, O.; Slowe, S.; Kitchen, I.; Befort, K.; Dierich, A.; Le Meur, M.; Dolle, P.; Tzavara, E.; Hanoune, J.; Roques, B.P.; Kieffer, B.L. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature, 1996, 383, 819-823.
-
(1996)
Nature
, vol.383
, pp. 819-823
-
-
Matthes, H.W.1
Maldonado, R.2
Simonin, F.3
Valverde, O.4
Slowe, S.5
Kitchen, I.6
Befort, K.7
Dierich, A.8
Le Meur, M.9
Dolle, P.10
Tzavara, E.11
Hanoune, J.12
Roques, B.P.13
Kieffer, B.L.14
-
153
-
-
0036498037
-
Alpha(2A)-adrenergic receptors are present in mu-opioid receptor containing neurons in rat medial nucleus tractus solitarius
-
Glass, M.J.; Pickel, V.M. Alpha(2A)-adrenergic receptors are present in mu-opioid receptor containing neurons in rat medial nucleus tractus solitarius. Synapse, 2002, 43, 208-218.
-
(2002)
Synapse
, vol.43
, pp. 208-218
-
-
Glass, M.J.1
Pickel, V.M.2
-
154
-
-
0346996861
-
Functional interactions between mu opioid and alpha 2A-adrenergic receptors
-
Jordan, B.A.; Gomes, I.; Rios, C.; Filipovska, J.; Devi, L.A. Functional interactions between mu opioid and alpha 2A-adrenergic receptors. Mol. Pharmacol., 2003, 64, 1317-1324.
-
(2003)
Mol. Pharmacol
, vol.64
, pp. 1317-1324
-
-
Jordan, B.A.1
Gomes, I.2
Rios, C.3
Filipovska, J.4
Devi, L.A.5
-
155
-
-
8744259035
-
Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles
-
Zhang, Y.Q.; Limbird, L.E. Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles. Biochem. Soc. Trans., 2004, 32, 856-860.
-
(2004)
Biochem. Soc. Trans
, vol.32
, pp. 856-860
-
-
Zhang, Y.Q.1
Limbird, L.E.2
-
156
-
-
38349054282
-
Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling
-
Vilardaga, J.P.; Nikolaev, V.O.; Lorenz, K.; Ferrandon, S.; Zhuang, Z.; Lohse, M.J. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nat. Chem. Biol., 2008, 4, 126-131.
-
(2008)
Nat. Chem. Biol
, vol.4
, pp. 126-131
-
-
Vilardaga, J.P.1
Nikolaev, V.O.2
Lorenz, K.3
Ferrandon, S.4
Zhuang, Z.5
Lohse, M.J.6
-
157
-
-
0018353187
-
Antinociceptive activity of clonidine and its potentiation of morphine analgesia
-
Spaulding, T.C.; Fielding, S.; Venafro, J.J.; Lal, H. Antinociceptive activity of clonidine and its potentiation of morphine analgesia. Eur. J. Pharmacol., 1979, 58, 19-25.
-
(1979)
Eur. J. Pharmacol
, vol.58
, pp. 19-25
-
-
Spaulding, T.C.1
Fielding, S.2
Venafro, J.J.3
Lal, H.4
-
158
-
-
0023096148
-
Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord
-
Wilcox, G.L.; Carlsson, K.H.; Jochim, A.; Jurna, I. Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord. Brain Res., 1987, 405, 84-93.
-
(1987)
Brain Res
, vol.405
, pp. 84-93
-
-
Wilcox, G.L.1
Carlsson, K.H.2
Jochim, A.3
Jurna, I.4
-
159
-
-
65249109909
-
P38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons
-
Tan, M.; Walwyn, W.M.; Evans, C.J.; Xie, C.W. p38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons. J. Biol. Chem., 2009, 284, 6270-6281.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 6270-6281
-
-
Tan, M.1
Walwyn, W.M.2
Evans, C.J.3
Xie, C.W.4
-
160
-
-
0023633892
-
Modulation of brain alpha 2-adrenoceptor and mu-opioid receptor densities during morphine dependence and spontaneous withdrawal in rats
-
Ulibarri, I.; Garcia-Sevilla, J.A.; Ugedo, L. Modulation of brain alpha 2-adrenoceptor and mu-opioid receptor densities during morphine dependence and spontaneous withdrawal in rats. Naunyn Schmiedebergs Arch. Pharmacol., 1987, 336, 530-537.
-
(1987)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.336
, pp. 530-537
-
-
Ulibarri, I.1
Garcia-Sevilla, J.A.2
Ugedo, L.3
-
161
-
-
0024513213
-
Changes in alpha 2-adrenoceptor number and function in brains of morphine-dependent rats
-
Smith, C.B.; Moises, H.C.; Spengler, R.N.; Hollingsworth, P.J. Changes in alpha 2-adrenoceptor number and function in brains of morphine-dependent rats. Eur. J. Pharmacol., 1989, 161, 111-119.
-
(1989)
Eur. J. Pharmacol
, vol.161
, pp. 111-119
-
-
Smith, C.B.1
Moises, H.C.2
Spengler, R.N.3
Hollingsworth, P.J.4
-
162
-
-
0028237284
-
Mu-Opioid receptor and alpha 2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts
-
Gabilondo, A.M.; Meana, J.J.; Barturen, F.; Sastre, M.; GarciaSevilla, J.A. Mu-Opioid receptor and alpha 2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts. Psychopharmacology (Berl.), 1994, 115, 135-140.
-
(1994)
Psychopharmacology (Berl.)
, vol.115
, pp. 135-140
-
-
Gabilondo, A.M.1
Meana, J.J.2
Barturen, F.3
Sastre, M.4
Garciasevilla, J.A.5
-
163
-
-
0033918387
-
Mu-opioid receptor and alpha2-adrenoceptor agonist stimulation of [35S]GTPgammaS binding to G-proteins in postmortem brains of opioid addicts
-
Meana, J.J.; Gonzalez-Maeso, J.; Garcia-Sevilla, J.A.; Guimon, J. mu-opioid receptor and alpha2-adrenoceptor agonist stimulation of [35S]GTPgammaS binding to G-proteins in postmortem brains of opioid addicts. Mol. Psychiatry, 2000, 5, 308-315.
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 308-315
-
-
Meana, J.J.1
Gonzalez-Maeso, J.2
Garcia-Sevilla, J.A.3
Guimon, J.4
-
164
-
-
0242460494
-
Metabotropic glutamate 1alpha and adenosine A1 receptors assemble into functionally interacting complexes
-
Ciruela, F.; Escriche, M.; Burgueno, J.; Angulo, E.; Casado, V.; Soloviev, M.M.; Canela, E.I.; Mallol, J.; Chan, W.Y.; Lluis, C.; McIlhinney, R.A.; Franco, R. Metabotropic glutamate 1alpha and adenosine A1 receptors assemble into functionally interacting complexes. J. Biol. Chem., 2001, 276, 18345-18351.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 18345-18351
-
-
Ciruela, F.1
Escriche, M.2
Burgueno, J.3
Angulo, E.4
Casado, V.5
Soloviev, M.M.6
Canela, E.I.7
Mallol, J.8
Chan, W.Y.9
Lluis, C.10
McIlhinney, R.A.11
Franco, R.12
-
165
-
-
0035898279
-
Adenosine preferentially suppresses serotonin2A receptor-enhanced excitatory postsynaptic currents in layer V neurons of the rat medial prefrontal cortex
-
Stutzmann, G.E.; Marek, G.J.; Aghajanian, G.K. Adenosine preferentially suppresses serotonin2A receptor-enhanced excitatory postsynaptic currents in layer V neurons of the rat medial prefrontal cortex. Neuroscience, 2001, 105, 55-69.
-
(2001)
Neuroscience
, vol.105
, pp. 55-69
-
-
Stutzmann, G.E.1
Marek, G.J.2
Aghajanian, G.K.3
-
166
-
-
67349099505
-
Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats
-
Marek, G.J. Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats. Neuropharmacology, 2009, 56, 1082-1087.
-
(2009)
Neuropharmacology
, vol.56
, pp. 1082-1087
-
-
Marek, G.J.1
-
167
-
-
47349118854
-
Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function
-
Ferrada, C.; Ferre, S.; Casado, V.; Cortes, A.; Justinova, Z.; Barnes, C.; Canela, E.I.; Goldberg, S.R.; Leurs, R.; Lluis, C.; Franco, R. Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function. Neuropharmacology, 2008, 55, 190-197.
-
(2008)
Neuropharmacology
, vol.55
, pp. 190-197
-
-
Ferrada, C.1
Ferre, S.2
Casado, V.3
Cortes, A.4
Justinova, Z.5
Barnes, C.6
Canela, E.I.7
Goldberg, S.R.8
Leurs, R.9
Lluis, C.10
Franco, R.11
-
168
-
-
34548299078
-
Heterooligomerization between vasotocin and corticotropin-releasing hormone (CRH) receptors augments CRH-stimulated 3',5'-cyclic adenosine monophosphate production
-
Mikhailova, M.V.; Mayeux, P.R.; Jurkevich, A.; Kuenzel, W.J.; Madison, F.; Periasamy, A.; Chen, Y.; Cornett, L.E. Heterooligomerization between vasotocin and corticotropin-releasing hormone (CRH) receptors augments CRH-stimulated 3',5'-cyclic adenosine monophosphate production. Mol. Endocrinol., 2007, 21, 2178-2188.
-
(2007)
Mol. Endocrinol
, vol.21
, pp. 2178-2188
-
-
Mikhailova, M.V.1
Mayeux, P.R.2
Jurkevich, A.3
Kuenzel, W.J.4
Madison, F.5
Periasamy, A.6
Chen, Y.7
Cornett, L.E.8
-
169
-
-
34248524346
-
Dimerization between vasopressin V1b and corticotropin releasing hormone type 1 receptors
-
Young, S.F.; Griffante, C.; Aguilera, G. Dimerization between vasopressin V1b and corticotropin releasing hormone type 1 receptors. Cell Mol. Neurobiol., 2007, 27, 439-461.
-
(2007)
Cell Mol. Neurobiol
, vol.27
, pp. 439-461
-
-
Young, S.F.1
Griffante, C.2
Aguilera, G.3
-
170
-
-
51649126450
-
Transmembrane domain IV of the Gallus gallus VT2 vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor
-
Mikhailova, M.V.; Blansett, J.; Jacobi, S.; Mayeux, P.R.; Cornett, L.E. Transmembrane domain IV of the Gallus gallus VT2 vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor. J. Biomed. Opt., 2008, 13, 031208.
-
(1208)
J. Biomed. Opt
, vol.13
, Issue.3
, pp. 2008
-
-
Mikhailova, M.V.1
Blansett, J.2
Jacobi, S.3
Mayeux, P.R.4
Cornett, L.E.5
-
171
-
-
33646526069
-
G-protein-coupled receptor heterodimers: Pharmacology, function and relevance to drug discovery
-
Milligan, G. G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery. Drug Discov. Today, 2006, 11, 541-549.
-
(2006)
Drug Discov. Today
, vol.11
, pp. 541-549
-
-
Milligan, G.1
-
172
-
-
34548421579
-
G-protein-coupled receptor heterodimerization: Assay technologies to clinical significance
-
Kent, T.; McAlpine, C.; Sabetnia, S.; Presland, J. G-protein-coupled receptor heterodimerization: assay technologies to clinical significance. Curr. Opin. Drug Discov. Devel., 2007, 10, 580-589.
-
(2007)
Curr. Opin. Drug Discov. Devel
, vol.10
, pp. 580-589
-
-
Kent, T.1
McAlpine, C.2
Sabetnia, S.3
Presland, J.4
-
173
-
-
44649101927
-
G protein-coupled receptor dimers: Functional consequences, disease states and drug targets
-
Dalrymple, M.B.; Pfleger, K.D.; Eidne, K.A. G protein-coupled receptor dimers: functional consequences, disease states and drug targets. Pharmacol. Ther., 2008, 118, 359-371.
-
(2008)
Pharmacol. Ther
, vol.118
, pp. 359-371
-
-
Dalrymple, M.B.1
Pfleger, K.D.2
Eidne, K.A.3
-
174
-
-
21144446486
-
A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers
-
Waldhoer, M.; Fong, J.; Jones, R.M.; Lunzer, M.M.; Sharma, S.K.; Kostenis, E.; Portoghese, P.S.; Whistler, J.L. A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers. Proc. Natl. Acad. Sci. USA, 2005, 102, 9050-9055.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9050-9055
-
-
Waldhoer, M.1
Fong, J.2
Jones, R.M.3
Lunzer, M.M.4
Sharma, S.K.5
Kostenis, E.6
Portoghese, P.S.7
Whistler, J.L.8
-
175
-
-
30044442319
-
Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series
-
Daniels, D.J.; Lenard, N.R.; Etienne, C.L.; Law, P.Y.; Roerig, S.C.; Portoghese, P.S. Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series. Proc. Natl. Acad. Sci. USA, 2005, 102, 19208-19213.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 19208-19213
-
-
Daniels, D.J.1
Lenard, N.R.2
Etienne, C.L.3
Law, P.Y.4
Roerig, S.C.5
Portoghese, P.S.6
-
176
-
-
25144488303
-
Interaction of bivalent ligand KDN21 with heterodimeric delta-kappa opioid receptors in human embryonic kidney 293 cells
-
Xie, Z.; Bhushan, R.G.; Daniels, D.J.; Portoghese, P.S. Interaction of bivalent ligand KDN21 with heterodimeric delta-kappa opioid receptors in human embryonic kidney 293 cells. Mol. Pharmacol., 2005, 68, 1079-1086.
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 1079-1086
-
-
Xie, Z.1
Bhushan, R.G.2
Daniels, D.J.3
Portoghese, P.S.4
-
177
-
-
33746256433
-
Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling
-
Breit, A.; Gagnidze, K.; Devi, L.A.; Lagace, M.; Bouvier, M. Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling. Mol. Pharmacol., 2006, 70, 686-696.
-
(2006)
Mol. Pharmacol
, vol.70
, pp. 686-696
-
-
Breit, A.1
Gagnidze, K.2
Devi, L.A.3
Lagace, M.4
Bouvier, M.5
-
178
-
-
19444364640
-
The paradoxical effects of SKF83959, a novel dopamine D1-like receptor agonist, in the rat acoustic startle reflex paradigm
-
Zhang, Z.J.; Jiang, X.L.; Zhang, S.E.; Hough, C.J.; Li, H.; Chen, J.G.; Zhen, X.C. The paradoxical effects of SKF83959, a novel dopamine D1-like receptor agonist, in the rat acoustic startle reflex paradigm. Neurosci. Lett., 2005, 382, 134-138.
-
(2005)
Neurosci. Lett
, vol.382
, pp. 134-138
-
-
Zhang, Z.J.1
Jiang, X.L.2
Zhang, S.E.3
Hough, C.J.4
Li, H.5
Chen, J.G.6
Zhen, X.C.7
-
179
-
-
46649088122
-
The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist
-
Natesan, S.; Reckless, G.E.; Barlow, K.B.; Odontiadis, J.; Nobrega, J.N.; Baker, G.B.; George, S.R.; Mamo, D.; Kapur, S. The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist. Psychopharmacology (Berl.), 2008, 199, 275-289.
-
(2008)
Psychopharmacology (Berl.)
, vol.199
, pp. 275-289
-
-
Natesan, S.1
Reckless, G.E.2
Barlow, K.B.3
Odontiadis, J.4
Nobrega, J.N.5
Baker, G.B.6
George, S.R.7
Mamo, D.8
Kapur, S.9
-
180
-
-
65449123343
-
Design of multivalent ligand targeting G-protein-coupled receptors
-
Liu, Z.; Zhang, J.; Zhang, A. Design of multivalent ligand targeting G-protein-coupled receptors. Curr. Pharm. Des., 2009, 15, 682-718.
-
(2009)
Curr. Pharm. Des
, vol.15
, pp. 682-718
-
-
Liu, Z.1
Zhang, J.2
Zhang, A.3
-
181
-
-
33847623714
-
Receptor dimerization--rationale for the design of bivalent ligands
-
Zhang, A.; Liu, Z.; Kan, Y. Receptor dimerization--rationale for the design of bivalent ligands. Curr. Top. Med. Chem., 2007, 7, 343-345.
-
(2007)
Curr. Top. Med. Chem
, vol.7
, pp. 343-345
-
-
Zhang, A.1
Liu, Z.2
Kan, Y.3
-
182
-
-
70349192980
-
Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers
-
Soriano, A.; Ventura, R.; Molero, A.; Hoen, R.; Casado, V.; Cortes, A.; Fanelli, F.; Albericio, F.; Lluis, C.; Franco, R.; Royo, M. Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers. J. Med. Chem., 2009, 52, 5590-5602.
-
(2009)
J. Med. Chem
, vol.52
, pp. 5590-5602
-
-
Soriano, A.1
Ventura, R.2
Molero, A.3
Hoen, R.4
Casado, V.5
Cortes, A.6
Fanelli, F.7
Albericio, F.8
Lluis, C.9
Franco, R.10
Royo, M.11
-
183
-
-
34548398610
-
Allosteric properties of G protein-coupled receptor oligomers
-
Springael, J.Y.; Urizar, E.; Costagliola, S.; Vassart, G.; Parmentier, M. Allosteric properties of G protein-coupled receptor oligomers. Pharmacol. Ther., 2007, 115, 410-418.
-
(2007)
Pharmacol. Ther
, vol.115
, pp. 410-418
-
-
Springael, J.Y.1
Urizar, E.2
Costagliola, S.3
Vassart, G.4
Parmentier, M.5
-
184
-
-
39149104024
-
GPCR monomers and oligomers: It takes all kinds
-
Gurevich, V.V.; Gurevich, E.V. GPCR monomers and oligomers: it takes all kinds. Trends Neurosci., 2008, 31, 74-81.
-
(2008)
Trends Neurosci
, vol.31
, pp. 74-81
-
-
Gurevich, V.V.1
Gurevich, E.V.2
-
185
-
-
68249159980
-
Crosstalk between GABA(B) and mGlu1a receptors reveals new insight into GPCR signal integration
-
Rives, M.L.; Vol, C.; Fukazawa, Y.; Tinel, N.; Trinquet, E.; Ayoub, M.A.; Shigemoto, R.; Pin, J.P.; Prezeau, L. Crosstalk between GABA(B) and mGlu1a receptors reveals new insight into GPCR signal integration. EMBO J., 2009, 28, 2195-2208.
-
(2009)
EMBO J
, vol.28
, pp. 2195-2208
-
-
Rives, M.L.1
Vol, C.2
Fukazawa, Y.3
Tinel, N.4
Trinquet, E.5
Ayoub, M.A.6
Shigemoto, R.7
Pin, J.P.8
Prezeau, L.9
-
186
-
-
0043029571
-
Detection of sweet and umami taste in the absence of taste receptor T1r3
-
Damak, S.; Rong, M.; Yasumatsu, K.; Kokrashvili, Z.; Varadarajan, V.; Zou, S.; Jiang, P.; Ninomiya, Y.; Margolskee, R.F. Detection of sweet and umami taste in the absence of taste receptor T1r3. Science, 2003, 301, 850-853.
-
(2003)
Science
, vol.301
, pp. 850-853
-
-
Damak, S.1
Rong, M.2
Yasumatsu, K.3
Kokrashvili, Z.4
Varadarajan, V.5
Zou, S.6
Jiang, P.7
Ninomiya, Y.8
Margolskee, R.F.9
-
187
-
-
0344823647
-
The receptors for mammalian sweet and umami taste
-
Zhao, G.Q.; Zhang, Y.; Hoon, M.A.; Chandrashekar, J.; Erlenbach, I.; Ryba, N.J.; Zuker, C.S. The receptors for mammalian sweet and umami taste. Cell, 2003, 115, 255-266.
-
(2003)
Cell
, vol.115
, pp. 255-266
-
-
Zhao, G.Q.1
Zhang, Y.2
Hoon, M.A.3
Chandrashekar, J.4
Erlenbach, I.5
Ryba, N.J.6
Zuker, C.S.7
-
188
-
-
0034668742
-
Heterodimerization of mu and delta opioid receptors: A role in opiate synergy
-
Gomes, I.; Jordan, B.A.; Gupta, A.; Trapaidze, N.; Nagy, V.; Devi, L.A. Heterodimerization of mu and delta opioid receptors: A role in opiate synergy. J. Neurosci., 2000, 20, RC110.
-
(2000)
J. Neurosci
, vol.20
-
-
Gomes, I.1
Jordan, B.A.2
Gupta, A.3
Trapaidze, N.4
Nagy, V.5
Devi, L.A.6
-
189
-
-
1842687121
-
A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia
-
Gomes, I.; Gupta, A.; Filipovska, J.; Szeto, H.H.; Pintar, J.E.; Devi, L.A. A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proc. Natl. Acad. Sci. USA, 2004, 101, 5135-5139.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5135-5139
-
-
Gomes, I.1
Gupta, A.2
Filipovska, J.3
Szeto, H.H.4
Pintar, J.E.5
Devi, L.A.6
-
190
-
-
0141841603
-
Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: A functional role for receptor-receptor interaction in vivo
-
Barki-Harrington, L.; Luttrell, L.M.; Rockman, H.A. Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation, 2003, 108, 1611-1618.
-
(2003)
Circulation
, vol.108
, pp. 1611-1618
-
-
Barki-Harrington, L.1
Luttrell, L.M.2
Rockman, H.A.3
-
191
-
-
14844300114
-
Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice
-
Deighan, C.; Methven, L.; Naghadeh, M.M.; Wokoma, A.; Macmillan, J.; Daly, C.J.; Tanoue, A.; Tsujimoto, G.; McGrath, J.C. Insights into the functional roles of alpha(1)-adrenoceptor subtypes in mouse carotid arteries using knockout mice. Br. J. Pharmacol., 2005, 144, 558-565.
-
(2005)
Br. J. Pharmacol
, vol.144
, pp. 558-565
-
-
Deighan, C.1
Methven, L.2
Naghadeh, M.M.3
Wokoma, A.4
Macmillan, J.5
Daly, C.J.6
Tanoue, A.7
Tsujimoto, G.8
McGrath, J.C.9
-
192
-
-
0021824455
-
Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo-and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting
-
Mattera, R.; Pitts, B.J.; Entman, M.L.; Birnbaumer, L. Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo-and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting. J. Biol. Chem., 1985, 260, 7410-7421.
-
(1985)
J. Biol. Chem
, vol.260
, pp. 7410-7421
-
-
Mattera, R.1
Pitts, B.J.2
Entman, M.L.3
Birnbaumer, L.4
-
193
-
-
0029083945
-
Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors
-
Wreggett, K.A.; Wells, J.W. Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. J. Biol. Chem., 1995, 270, 22488-22499.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 22488-22499
-
-
Wreggett, K.A.1
Wells, J.W.2
-
194
-
-
54049106162
-
Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: Insight into nanoscale organization of signal transduction
-
Pontier, S.M.; Percherancier, Y.; Galandrin, S.; Breit, A.; Gales, C.; Bouvier, M. Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction. J. Biol. Chem., 2008, 283, 24659-24672.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 24659-24672
-
-
Pontier, S.M.1
Percherancier, Y.2
Galandrin, S.3
Breit, A.4
Gales, C.5
Bouvier, M.6
-
195
-
-
62149128233
-
Differential coupling of the vasopressin V1b receptor through compartmentalization within the plasma membrane
-
Orcel, H.; Albizu, L.; Perkovska, S.; Durroux, T.; Mendre, C.; Ansanay, H.; Mouillac, B.; Rabie, A. Differential coupling of the vasopressin V1b receptor through compartmentalization within the plasma membrane. Mol. Pharmacol., 2009, 75, 637-647.
-
(2009)
Mol. Pharmacol
, vol.75
, pp. 637-647
-
-
Orcel, H.1
Albizu, L.2
Perkovska, S.3
Durroux, T.4
Mendre, C.5
Ansanay, H.6
Mouillac, B.7
Rabie, A.8
-
196
-
-
0036733284
-
Caveolae: From cell biology to animal physiology
-
Razani, B.; Woodman, S.E.; Lisanti, M.P. Caveolae: from cell biology to animal physiology. Pharmacol. Rev., 2002, 54, 431-467.
-
(2002)
Pharmacol. Rev
, vol.54
, pp. 431-467
-
-
Razani, B.1
Woodman, S.E.2
Lisanti, M.P.3
-
197
-
-
34948854685
-
Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands
-
Albizu, L.; Teppaz, G.; Seyer, R.; Bazin, H.; Ansanay, H.; Manning, M.; Mouillac, B.; Durroux, T. Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands. J. Med. Chem., 2007, 50, 4976-4985.
-
(2007)
J. Med. Chem
, vol.50
, pp. 4976-4985
-
-
Albizu, L.1
Teppaz, G.2
Seyer, R.3
Bazin, H.4
Ansanay, H.5
Manning, M.6
Mouillac, B.7
Durroux, T.8
-
198
-
-
77955874300
-
Time-resolved FRET between ligands bound on asymmetric G protein-coupled receptors reveals oligomers in native tissues
-
in press
-
Albizu, L.; Cottet, M.; Stoev, S.; Seyer, R.; Brabet, I.; Roux, T.; Bazin, H.; Bourrier, E.; Lamarque, L.; Breton, C.; Rives, M-L.; Kralikova, M.; Newman A.H.; Javitch, J.A.; Trinquet, E.; Manning, M.; Pin, J-P.; Mouillac, B.; Durroux, T. Time-resolved FRET between ligands bound on asymmetric G protein-coupled receptors reveals oligomers in native tissues. Nat. Chem. Biol., 2010, in press.
-
(2010)
Nat. Chem. Biol
-
-
Albizu, L.1
Cottet, M.2
Stoev, S.3
Seyer, R.4
Brabet, I.5
Roux, T.6
Bazin, H.7
Bourrier, E.8
Lamarque, L.9
Breton, C.10
Rives, M.-L.11
Kralikova, M.12
Newman, A.H.13
Javitch, J.A.14
Trinquet, E.15
Manning, M.16
Pin, J.-P.17
Mouillac, B.18
Durroux, T.19
-
199
-
-
0027661965
-
Receptor-receptor interactions as an integrative mechanism in nerve cells
-
Zoli, M.; Agnati, L.F.; Hedlund, P.B.; Li, X.M.; Ferre, S.; Fuxe, K. Receptor-receptor interactions as an integrative mechanism in nerve cells. Mol. Neurobiol., 1993, 7, 293-334.
-
(1993)
Mol. Neurobiol
, vol.7
, pp. 293-334
-
-
Zoli, M.1
Agnati, L.F.2
Hedlund, P.B.3
Li, X.M.4
Ferre, S.5
Fuxe, K.6
-
200
-
-
0142010014
-
Possible role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: Focus on motor learning in the basal ganglia
-
Agnati, L.F.; Franzen, O.; Ferre, S.; Leo, G.; Franco, R.; Fuxe, K. Possible role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia. J. Neural Transm. Suppl., 2003, 1-28.
-
(2003)
J. Neural Transm. Suppl
, pp. 1-28
-
-
Agnati, L.F.1
Franzen, O.2
Ferre, S.3
Leo, G.4
Franco, R.5
Fuxe, K.6
-
201
-
-
33847419390
-
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers
-
Pin, J.P.; Neubig, R.; Bouvier, M.; Devi, L.; Filizola, M.; Javitch, J.A.; Lohse, M.J.; Milligan, G.; Palczewski, K.; Parmentier, M.; Spedding, M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacol. Rev., 2007, 59, 5-13.
-
(2007)
Pharmacol. Rev
, vol.59
, pp. 5-13
-
-
Pin, J.P.1
Neubig, R.2
Bouvier, M.3
Devi, L.4
Filizola, M.5
Javitch, J.A.6
Lohse, M.J.7
Milligan, G.8
Palczewski, K.9
Parmentier, M.10
Spedding, M.11
-
202
-
-
33947362780
-
The alpha1b-adrenoceptor exists as a higher-order oligomer: Effective oligomerization is required for receptor maturation, surface delivery, and function
-
Lopez-Gimenez, J.F.; Canals, M.; Pediani, J.D.; Milligan, G. The alpha1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function. Mol. Pharmacol., 2007, 71, 1015-1029.
-
(2007)
Mol. Pharmacol
, vol.71
, pp. 1015-1029
-
-
Lopez-Gimenez, J.F.1
Canals, M.2
Pediani, J.D.3
Milligan, G.4
-
203
-
-
51049112029
-
Dopamine D2 receptors form higher order oligomers at physiological expression levels
-
Guo, W.; Urizar, E.; Kralikova, M.; Mobarec, J.C.; Shi, L.; Filizola, M.; Javitch, J.A. Dopamine D2 receptors form higher order oligomers at physiological expression levels. EMBO J., 2008, 27, 2293-2304.
-
(2008)
EMBO J
, vol.27
, pp. 2293-2304
-
-
Guo, W.1
Urizar, E.2
Kralikova, M.3
Mobarec, J.C.4
Shi, L.5
Filizola, M.6
Javitch, J.A.7
-
204
-
-
70649113078
-
G-protein-coupled receptor oligomers: Two or more for what? Lessons from mGlu and GABA(B) receptors
-
Pin, J.P.; Comps-Agrar, L.; Maurel, D.; Monnier, C.; Rives, M.L.; Trinquet, E.; Kniazeff, J.; Rondard, P.; Prezeau, L. G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABA(B) receptors. J. Physiol., 2009, 587, 5337-5344.
-
(2009)
J. Physiol
, vol.587
, pp. 5337-5344
-
-
Pin, J.P.1
Comps-Agrar, L.2
Maurel, D.3
Monnier, C.4
Rives, M.L.5
Trinquet, E.6
Kniazeff, J.7
Rondard, P.8
Prezeau, L.9
-
205
-
-
44449096254
-
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: Application to GPCR oligomerization
-
Maurel, D.; Comps-Agrar, L.; Brock, C.; Rives, M.L.; Bourrier, E.; Ayoub, M.A.; Bazin, H.; Tinel, N.; Durroux, T.; Prezeau, L.; Trinquet, E.; Pin, J.P. Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization. Nat. Methods, 2008, 5, 561-567.
-
(2008)
Nat. Methods
, vol.5
, pp. 561-567
-
-
Maurel, D.1
Comps-Agrar, L.2
Brock, C.3
Rives, M.L.4
Bourrier, E.5
Ayoub, M.A.6
Bazin, H.7
Tinel, N.8
Durroux, T.9
Prezeau, L.10
Trinquet, E.11
Pin, J.P.12
-
206
-
-
4944256731
-
GPCR-GIP networks: A first step in the discovery of new therapeutic drugs
-
Bockaert, J.; Dumuis, A.; Fagni, L.; Marin, P. GPCR-GIP networks: a first step in the discovery of new therapeutic drugs? Curr. Opin. Drug Discov. Devel., 2004, 7, 649-657.
-
(2004)
Curr. Opin. Drug Discov. Devel
, vol.7
, pp. 649-657
-
-
Bockaert, J.1
Dumuis, A.2
Fagni, L.3
Marin, P.4
-
207
-
-
34548789127
-
A proteomic approach to receptor signaling: Molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex
-
Kabbani, N.; Levenson, R. A proteomic approach to receptor signaling: molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex. Eur. J. Pharmacol., 2007, 572, 83-93.
-
(2007)
Eur. J. Pharmacol
, vol.572
, pp. 83-93
-
-
Kabbani, N.1
Levenson, R.2
|