The selective mGlu5 receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D2 receptors in the rat striatum: Interactions with adenosine A2a receptors

Neuropsychopharmacology

Volumn 25, Issue 4, 2001, Pages 505-513

  Popoli, Patrizia ^a   Pèzzola, Antonella ^a   Torvinen, Maria ^b   Reggio, Rosaria ^a   Pintor, Annita ^a   Scarchilli, Laura ^a   Fuxe, Kjell ^b   Ferré, Sergi ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adenosine A2A receptors; CHPG; Dopamine D2 receptors; Metabotropic glutamate (mGlu) receptors; Parkinson's disease; Striatum

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLORO 5 HYDROXYPHENYLGLYCINE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; APOMORPHINE; DOPAMINE 2 RECEPTOR; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; OXIDOPAMINE; QUINPIROLE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; DRUG EFFECT; DRUG INHIBITION; DRUG POTENTIATION; MALE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; ANIMALS; DOPAMINE; DOPAMINE AGONISTS; EXCITATORY AMINO ACID AGONISTS; EXTRACELLULAR SPACE; FUNCTIONAL LATERALITY; GLYCINE; INJECTIONS, INTRAVENTRICULAR; MALE; MICRODIALYSIS; MOTOR ACTIVITY; NEOSTRIATUM; OXIDOPAMINE; PHENYLACETATES; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A2A; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, PURINERGIC P1; STEREOTYPED BEHAVIOR; SYMPATHECTOMY, CHEMICAL;

EID: 0034856088     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(01)00256-1     Document Type: Article

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