Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst3 receptor function by heterodimerization with sst2A

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 14027-14036

  Pfeiffer, Manuela ^b   Koch, Thomas ^b   Schröder, Helmut ^b   Klutzny, Marcus ^b   Kirscht, Susanne ^b   Kreienkamp, Hans Jürgen ^b   Höllt, Volker ^b   Schulz, Stefan ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; CELLS; HORMONES; OLIGOMERS; TISSUE;

EPITOPE-TAGGED RECEPTORS;

PROTEINS;

4 AMINOBUTYRIC ACID; ADENYLATE CYCLASE; CYCLIC AMP; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; RECEPTOR SUBTYPE; SOMATOSTATIN 14; SOMATOSTATIN RECEPTOR; SULFUR 35; AMIDE; EPITOPE; INDOLE DERIVATIVE; L 779976; SOMATOSTATIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; EMBRYO; ENZYME ACTIVATION; ENZYME ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; KIDNEY CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; WESTERN BLOTTING; CELL LINE; CELL MEMBRANE; CHEMISTRY; DOSE RESPONSE; ENDOCYTOSIS; IC 50; IMMUNOHISTOCHEMISTRY; KINETICS; METABOLISM; PROTEIN BINDING; SERODIAGNOSIS; SIGNAL TRANSDUCTION;

ANIMALIA; HOMO; MAMMALIA;

ADENYLATE CYCLASE; AMIDES; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; ENZYME ACTIVATION; EPITOPES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; MITOGEN-ACTIVATED PROTEIN KINASES; PRECIPITIN TESTS; PROTEIN BINDING; RECEPTORS, SOMATOSTATIN; SIGNAL TRANSDUCTION; SOMATOSTATIN; TRANSFECTION;

EID: 0035958027     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006084200     Document Type: Article

References (31)

1. Hebert, T. E., Moffett, S., Morello, J. P., Loisel, T. P., Bichet, D. G., Barret, C., and Bouvier, M. (1996) J. Biol. Chem. 271, 16384-16392
2. Cvejic, S., and Devi, L. A. (1997) J. Biol. Chem. 272, 26959-26964
3. Jordan, B. A., and Devi, L. A. (1999) Nature 399, 697-700
4. Romano, C., Yang, W. L., and O'Malley, K. L. (1996) J. Biol. Chem. 271, 28612-28616
5. Bai, M., Trivedi, S., and Brown, E. M. (1996) J. Biol. Chem. 273, 23605-23610
6. Zeng, P. Y., and Wess, J. (1999) J. Biol. Chem. 274, 19487-19497
7. George, S. R., Lee, S. P., Varghese, G., Zeman, P. R., Seeman, P., Ng, G. Y., and O'Dowd, B. F. (1998) J. Biol. Chem. 273, 30244-30248
8. Ng, G. Y., O'Dowd, B. F., Lee, S. P., Chung, H. T., Brann, M. R., Seeman, P., and George, S. R. (1996) Biochem. Biophys. Res. Commun. 227, 200-204
9. Pace, A. J., Gama, L., and Breitwieser, G. E. (1999) J. Biol. Chem. 274, 11629-11634
10. Ward, D. T., Brown, E. M., and Harris, H. W. (1998) J. Biol. Chem. 273, 14476-14483
11. Angers, S., Salahpour, A., Joly, E., Hilairet, S., Chelsky, D., Dennis, M., and Bouvier, M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 3684-3689
12. AbdAlla, S., Lother, H., and Quitterer, U. (2000) Nature 407, 94-98
13. George, S. R., Fan, T., Xie, Z., Tse, R., Tam, V., Varghese, G., and O'Dowd, B. F. (2000) J. Biol. Chem. 275, 26128-26135
14. Jones, K. A., Borowsky, B., Tamm, J. A., Craig, D. A., Durkin, M. M., Dai, M., Yao, W. J., Johnson, M., Gunwaldsen, C., Huang, L. Y., Tang, C., Shen, Q., Salon, J. A., Morse, K., Laz, T., Smith, K. E., Nagarathnam, D., Noble, S. A., Branchek, T. A., and Gerald, C. (1998) Nature 396, 674-679
15. Kaupmann, K., Malitschek, B., Schuler, V., Heid, J., Froestl, W., Beck, P., Mosbacher, J., Bischoff, S., Kulik, A., Shigemoto, R., Karschin, A., and Bettler, B. (1998) Nature 396, 683-687
16. Kuner, R., Kohr, G., Grunewald, S., Eisenhardt, G., Bach, A., and Kornau, H. C. (1999) Science 283, 74-77
17. Ng, G. Y., Clark, J., Coulombe, N., Ethier, N., Hebert, T. E., Sullivan, R., Kargman, S., Chateauneuf, A., Tsukamoto, N., McDonald, T., Whiting, P., Mezey, E., Johnson, M. P., Liu, Q., Kolakowski, L. F., Jr., Evans, J. F., Bonner, T. I., and O'Neill, G. P. (1999) J. Biol. Chem. 274, 7607-7610
18. White, J. H., Wise, A., Main, M. J., Green, A. Fraser, N. J., Disney, G. H., Barnes, A. A., Emson, P., Foord, S. M., and Marshall, F. H. (1998) Nature 396, 679-682
19. Marshall, F. H., Jones, K. A., Kaupmann, K., and Bettler, B. (1999) Trends Pharmacol. Sci. 20, 396-399
20. Rocheville, M., Lange, D. C., Kumar, U., Patel, S. C., Patel, R. C., and Patel, Y. C. (2000) Science 288, 154-157
21. Meyerhof, W. (1998) Rev. Physiol. Biochem. Pharmacol. 133, 55-108
22. Patel, Y. C. (1999) Front. Neuroendocrinol. 20, 157-198
23. Rocheville, M., Lange, D. C., Kumar, U., Sasi, R., Patel, R. C., and Patel, Y. C. (2000) J. Biol. Chem. 275, 7862-7869
24. Rohrer, S. P., Birzin, E. T., Mosley, R. T., Berk, S. C., Hutchins, S. M., Shen, D. M., Xiong, Y., Hayes, E. C., Parmar, R. M., Foor, F., Mitra, S. W., Degrado, S. J., Shu, M., Klopp, J. M., Cai, S. J., Blake, A., Chan, W. W., Pasternak, A., Yang, L., Patchett, A. A., Smith, R. G., Chapman, K. T., and Schaeffer, J. M. (1998) Science 282, 737-740
25. Schulz, S., Schmidt, H., Handel, M., Schreff, M., and Hollt, V. (1998) Neurosci. Lett. 257, 37-40
26. Schulz, S., Schreff, M., Schmidt, H., Handel, M., Przewlocki, R., and Hollt, V. (1998) Eur. J. Neurosci. 10, 3766-3768
27. Handel, M., Schulz, S., Stanarius, A., Schreff, M., Erdtmann-Vourliotis, M., Schmidt, H., Wolf, G., and Hollt, V. (1999) Neuroscience 89, 909-926
28. Kaupmann, K., Bruns, C., Hoyer, D., Seuwen, K., and Lubbert, H. (1993) FEBS Lett. 331, 53-59
29. Perez, J., Rigo, M., Kaupmann, K., Bruns, C., Yasuda, K., Bell, G. I., Lubbert, H., and Hoyer, D. (1994) Naunyn-Schmiedeberg's Arch. Pharmacol. 349, 145-160
30. Schulz, S., Schmitt, J., Wiborny, D., Schmidt, H., Olbricht, S., Weise, W., Roessner, A., Gramsch, C., and Hollt, V. (1998) Clin. Cancer Res. 4, 2047-2052
31. Schulz, S., Pauli, S. U., Handel, M., Dietzmann, K., Firsching, R., and Hollt, V. (2000) Clin. Cancer Res. 6, 1865-1874