Heterodimerization of β1- and β2-adrenergic receptor subtypes optimizes β-adrenergic modulation of cardiac contractility

Circulation Research

Volumn 97, Issue 3, 2005, Pages 244-251

  Zhu, Wei Zhong ^a   Chakir, Khalid ^a   Zhang, Shengjun ^a   Yang, Dongmei ^a   Lavoie, Catherine ^b,c   Bouvier, Michel ^c   Hébert, Terence E ^c   Lakatta, Edward G ^a   Cheng, Heping ^a   Xiao, Rui Ping ^a,d  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b MONTREAL HEART INSTITUTE   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d PEKING UNIVERSITY   (China)

Author keywords

adrenergic receptor; Cardiac contractility; G protein coupled receptors; Ligand binding; Receptor dimerization

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; ISOPRENALINE; RECEPTOR SUBTYPE; LIGAND;

ADRENERGIC ACTIVITY; ANIMAL CELL; ARTICLE; BINDING AFFINITY; DIMERIZATION; DOSE RESPONSE; HEART MUSCLE CONTRACTILITY; IMMUNOPRECIPITATION; LIGAND BINDING; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; ANIMAL; CHEMISTRY; DRUG EFFECT; HEART CONTRACTION; HEART MUSCLE CELL; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADRENERGIC BETA-AGONISTS; ANIMALS; CYCLIC AMP; DIMERIZATION; IMMUNOPRECIPITATION; LIGANDS; MALE; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 23344449115     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000176764.38934.86     Document Type: Article

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