-
1
-
-
0038392702
-
Structure-based analysis of GPCR function: Evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein
-
Baneres JL and Parello J (2003) Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein. J Mol Biol 329:815-829.
-
(2003)
J Mol Biol
, vol.329
, pp. 815-829
-
-
Baneres, J.L.1
Parello, J.2
-
2
-
-
0030712312
-
Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by Ccr5delta32
-
Benkirane M, Jin DY, Chun RF, Koup RA, and Jeang KT (1997) Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by Ccr5delta32. J Biol Chem 272:30603-30606.
-
(1997)
J Biol Chem
, vol.272
, pp. 30603-30606
-
-
Benkirane, M.1
Jin, D.Y.2
Chun, R.F.3
Koup, R.A.4
Jeang, K.T.5
-
3
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism and disease
-
Berger EA, Murphy PM, and Farber JM (1999) Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism and disease. Annu Rev Immunol 17:657-700.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
4
-
-
0033516460
-
Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity
-
Blanpain C, Lee B, Vakili J, Doranz BJ, Govaerts C, Migeotte I, Sharron M, Dupriez V, Vassart G, Doms RW, et al. (1999a) Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity. J Biol Chem 274:18902-18908.
-
(1999)
J Biol Chem
, vol.274
, pp. 18902-18908
-
-
Blanpain, C.1
Lee, B.2
Vakili, J.3
Doranz, B.J.4
Govaerts, C.5
Migeotte, I.6
Sharron, M.7
Dupriez, V.8
Vassart, G.9
Doms, R.W.10
-
5
-
-
0033567969
-
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist
-
Blanpain C, Migeotte I, Lee B, Vakili J, Doranz BJ, Govaerts C, Vassart G, Doms RW, and Parmentier M (1999b) CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood 94:1899-1905.
-
(1999)
Blood
, vol.94
, pp. 1899-1905
-
-
Blanpain, C.1
Migeotte, I.2
Lee, B.3
Vakili, J.4
Doranz, B.J.5
Govaerts, C.6
Vassart, G.7
Doms, R.W.8
Parmentier, M.9
-
6
-
-
0032572719
-
Decreased lesion formation in CCR2-/- Mice reveals a role for chemokines in the initiation of atherosclerosis
-
Boring L, Gosling J, Cleary M, and Charo IF (1998) Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature (Lond) 394:894-897.
-
(1998)
Nature (Lond)
, vol.394
, pp. 894-897
-
-
Boring, L.1
Gosling, J.2
Cleary, M.3
Charo, I.F.4
-
7
-
-
0028316908
-
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails
-
Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, and Coughlin SR (1994) Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci USA 91:2752-2756.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2752-2756
-
-
Charo, I.F.1
Myers, S.J.2
Herman, A.3
Franci, C.4
Connolly, A.J.5
Coughlin, S.R.6
-
8
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia growth and development study, multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
-
Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, Goedert JJ, Buchbinder SP, Vittinghoff E, Gomperts E, et al. (1996) Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia growth and development study, multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science (Wash DC) 273:1856-1862.
-
(1996)
Science (Wash DC)
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
Huttley, G.A.4
Smith, M.W.5
Allikmets, R.6
Goedert, J.J.7
Buchbinder, S.P.8
Vittinghoff, E.9
Gomperts, E.10
-
9
-
-
0031296740
-
Characterization of the CCR2 chemokine receptor: Functional CCR2 receptor expression in B cells
-
Frade JM, Mellado M, del Real G, Gutierrez-Ramos JC, Lind P, and Martinez A (1997) Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. J Immunol 159:5576-5584.
-
(1997)
J Immunol
, vol.159
, pp. 5576-5584
-
-
Frade, J.M.1
Mellado, M.2
Del Real, G.3
Gutierrez-Ramos, J.C.4
Lind, P.5
Martinez, A.6
-
11
-
-
10744223537
-
Identification of amino acid residues crucial for chemokine receptor dimerization
-
Hernanz-Falcon P, Rodriguez-Frade JM, Serrano A, Juan D, del Sol A, Soriano SF, Roncal F, Gomez L, Valencia A, Martinez A, et al. (2004) Identification of amino acid residues crucial for chemokine receptor dimerization. Nat Immunol 5:216-223.
-
(2004)
Nat Immunol
, vol.5
, pp. 216-223
-
-
Hernanz-Falcon, P.1
Rodriguez-Frade, J.M.2
Serrano, A.3
Juan, D.4
Del Sol, A.5
Soriano, S.F.6
Roncal, F.7
Gomez, L.8
Valencia, A.9
Martinez, A.10
-
12
-
-
0037144581
-
Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors
-
Issafras H, Angers S, Bulenger S, Blanpain C, Parmentier M, Labbe-Jullie C, Bouvier M, and Marullo S (2002) Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors. J Biol Chem 277:34666-34673.
-
(2002)
J Biol Chem
, vol.277
, pp. 34666-34673
-
-
Issafras, H.1
Angers, S.2
Bulenger, S.3
Blanpain, C.4
Parmentier, M.5
Labbe-Jullie, C.6
Bouvier, M.7
Marullo, S.8
-
13
-
-
0033578005
-
G-Protein-coupled receptor heterodimerization modulates receptor function
-
Jordan BA and Devi LA (1999) G-Protein-coupled receptor heterodimerization modulates receptor function. Nature (Lond) 399:697-700.
-
(1999)
Nature (Lond)
, vol.399
, pp. 697-700
-
-
Jordan, B.A.1
Devi, L.A.2
-
14
-
-
0029991350
-
Transfecting mammalian cells: Optimization of critical parameters affecting calcium-phosphate precipitate formation
-
Jordan M, Schallhorn A, and Wurm FM (1996) Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation. Nucleic Acids Res 24:596-601.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 596-601
-
-
Jordan, M.1
Schallhorn, A.2
Wurm, F.M.3
-
15
-
-
0032542382
-
GABA(B)-receptor subtypes assemble into functional heteromeric complexes
-
Kaupmann K, Malitschek B, Schuler V, Heid J, Froestl W, Beck P, Mosbacher J, Bischoff S, Kulik A, Shigemoto R, et al. (1998) GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature (Lond) 396:683-687.
-
(1998)
Nature (Lond)
, vol.396
, pp. 683-687
-
-
Kaupmann, K.1
Malitschek, B.2
Schuler, V.3
Heid, J.4
Froestl, W.5
Beck, P.6
Mosbacher, J.7
Bischoff, S.8
Kulik, A.9
Shigemoto, R.10
-
16
-
-
0033515588
-
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function
-
Lee B, Sharron M, Blanpain C, Doranz BJ, Vakili J, Setoh P, Berg E, Liu G, Guy HR, Durell SR, et al. (1999) Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem 274:9617-9626.
-
(1999)
J Biol Chem
, vol.274
, pp. 9617-9626
-
-
Lee, B.1
Sharron, M.2
Blanpain, C.3
Doranz, B.J.4
Vakili, J.5
Setoh, P.6
Berg, E.7
Liu, G.8
Guy, H.R.9
Durell, S.R.10
-
17
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 Infection
-
Liu R, Paxton WA, Choe S, Ceradini D, Martin SR, Horuk R, MacDonald ME, Stuhlmann H, Koup RA, and Landau NR (1996) Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 Infection. Cell 86:367-377.
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
Ceradini, D.4
Martin, S.R.5
Horuk, R.6
MacDonald, M.E.7
Stuhlmann, H.8
Koup, R.A.9
Landau, N.R.10
-
18
-
-
17144473106
-
Chemokine receptor homo- or heterodimerization activates distinct signaling pathways
-
Mellado M, Rodriguez-Frade JM, Vila-Coro AJ, Fernandez S, Martin d A, Jones DR, Toran JL, and Martinez A (2001) Chemokine receptor homo- or heterodimerization activates distinct signaling pathways. EMBO (Eur Mol Biol Organ) J 20:2497-2507.
-
(2001)
EMBO (Eur Mol Biol Organ) J
, vol.20
, pp. 2497-2507
-
-
Mellado, M.1
Rodriguez-Frade, J.M.2
Vila-Coro, A.J.3
Fernandez, S.4
Martin, D.A.5
Jones, D.R.6
Toran, J.L.7
Martinez, A.8
-
19
-
-
0030797831
-
The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression
-
Michael NL, Louie LG, Rohrbaugh AL, Schultz KA, Dayhoff DE, Wang CE, and Sheppard HW (1997) The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression. Nat Med 3:1160-1162.
-
(1997)
Nat Med
, vol.3
, pp. 1160-1162
-
-
Michael, N.L.1
Louie, L.G.2
Rohrbaugh, A.L.3
Schultz, K.A.4
Dayhoff, D.E.5
Wang, C.E.6
Sheppard, H.W.7
-
20
-
-
0033214480
-
Enhanced expression, native purification and characterization of CCR5, a principal HIV-1 coreceptor
-
Mirzabekov T, Bannert N, Farzan M, Hofmann W, Kolchinsky P, Wu L, Wyatt R, and Sodroski J (1999) Enhanced expression, native purification and characterization of CCR5, a principal HIV-1 coreceptor. J Biol Chem 274:28745-28750.
-
(1999)
J Biol Chem
, vol.274
, pp. 28745-28750
-
-
Mirzabekov, T.1
Bannert, N.2
Farzan, M.3
Hofmann, W.4
Kolchinsky, P.5
Wu, L.6
Wyatt, R.7
Sodroski, J.8
-
21
-
-
0034092634
-
International Union of Pharmacology. XXII. Nomenclature for chemokine receptors
-
Murphy PM, Baggiolini M, Charo IF, Hebert CA, Horuk R, Matsushima K, Miller LH, Oppenheim JJ, and Power CA (2000) International Union of Pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 52:145-176.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 145-176
-
-
Murphy, P.M.1
Baggiolini, M.2
Charo, I.F.3
Hebert, C.A.4
Horuk, R.5
Matsushima, K.6
Miller, L.H.7
Oppenheim, J.J.8
Power, C.A.9
-
22
-
-
0033120514
-
Chemokine receptor responses on t cells are achieved through regulation of both receptor expression and signaling
-
Rabin RL, Park MK, Liao F, Swofford R, Stephany D, and Farber JM (1999) Chemokine receptor responses on t cells are achieved through regulation of both receptor expression and signaling. J Immunol 162:3840-3850.
-
(1999)
J Immunol
, vol.162
, pp. 3840-3850
-
-
Rabin, R.L.1
Park, M.K.2
Liao, F.3
Swofford, R.4
Stephany, D.5
Farber, J.M.6
-
23
-
-
0033616765
-
The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2
-
Rodriguez-Frade JM, Vila-Coro AJ, de Ana AM, Albar JP, Martinez A, and Mellado M (1999) The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2. Proc Natl Acad Sci USA 96:3628-3633.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3628-3633
-
-
Rodriguez-Frade, J.M.1
Vila-Coro, A.J.2
De Ana, A.M.3
Albar, J.P.4
Martinez, A.5
Mellado, M.6
-
24
-
-
0029986131
-
Molecular cloning and functional expression of a new human CC-chemokine receptor gene
-
Samson M, Labbe O, Mollereau C, Vassart G, and Parmentier M (1996a) molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry 35:3362-3367.
-
(1996)
Biochemistry
, vol.35
, pp. 3362-3367
-
-
Samson, M.1
Labbe, O.2
Mollereau, C.3
Vassart, G.4
Parmentier, M.5
-
25
-
-
0030763382
-
The second extracellular loop of CCR5 is the major determinant of ligand specificity
-
Samson M, LaRosa G, Libert F, Paindavoine P, Detheux M, Vassart G, and Parmentier M (1997) The second extracellular loop of CCR5 is the major determinant of ligand specificity. J Biol Chem 272:24934-24941.
-
(1997)
J Biol Chem
, vol.272
, pp. 24934-24941
-
-
Samson, M.1
LaRosa, G.2
Libert, F.3
Paindavoine, P.4
Detheux, M.5
Vassart, G.6
Parmentier, M.7
-
26
-
-
16044373004
-
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor Gene
-
Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, Saragosti S, Lapoumeroulie C, Cognaux J, Forceille C, et al. (1996b) Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor Gene. Nature (Lond) 382:722-725.
-
(1996)
Nature (Lond)
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
Rucker, J.4
Liesnard, C.5
Farber, C.M.6
Saragosti, S.7
Lapoumeroulie, C.8
Cognaux, J.9
Forceille, C.10
-
27
-
-
0030861904
-
Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study
-
Smith MW, Dean M, Carrington M, Winkler C, Huttley GA, Lomb DA, Goedert JJ, O'Brien TR, Jacobson LP, Kaslow R, et al. (1997) Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science (Wash DC) 277:959-965.
-
(1997)
Science (Wash DC)
, vol.277
, pp. 959-965
-
-
Smith, M.W.1
Dean, M.2
Carrington, M.3
Winkler, C.4
Huttley, G.A.5
Lomb, D.A.6
Goedert, J.J.7
O'Brien, T.R.8
Jacobson, L.P.9
Kaslow, R.10
-
28
-
-
0034724420
-
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization
-
Vila-Coro AJ, Mellado M, Martin d A, Lucas P, del Real G, Martinez A, and Rodriguez-Frade JM (2000) HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization. Proc Natl Acad Sci USA 97:3388-3393.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3388-3393
-
-
Vila-Coro, A.J.1
Mellado, M.2
Martin, D.A.3
Lucas, P.4
Del Real, G.5
Martinez, A.6
Rodriguez-Frade, J.M.7
-
29
-
-
17444380779
-
Heterodimerization is required for the formation of a functional GABA(B) receptor
-
White JH, Wise A, Main MJ, Green A, Fraser NJ, Disney GH, Barnes AA, Emson P, Foord SM, and Marshall FH (1998) Heterodimerization is required for the formation of a functional GABA(B) receptor. Nature (Lond) 396:679-682.
-
(1998)
Nature (Lond)
, vol.396
, pp. 679-682
-
-
White, J.H.1
Wise, A.2
Main, M.J.3
Green, A.4
Fraser, N.J.5
Disney, G.H.6
Barnes, A.A.7
Emson, P.8
Foord, S.M.9
Marshall, F.H.10
-
30
-
-
0035912846
-
Heteromeric association creates a P2Y-like adenosine receptor
-
Yoshioka K, Saitoh O, and Nakata H (2001) Heteromeric association creates a P2Y-like adenosine receptor. Proc Natl Acad Sci USA 98:7617-7622.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7617-7622
-
-
Yoshioka, K.1
Saitoh, O.2
Nakata, H.3
|