Dimerization between vasopressin V1b and corticotropin releasing hormone type 1 receptors

Cellular and Molecular Neurobiology

Volumn 27, Issue 4, 2007, Pages 439-461

  Young, Sharla F ^a   Griffante, Cristiana ^a,b   Aguilera, Greti ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b GSK   (Italy)

Author keywords

BRET; Corticotropin releasing hormone type 1 receptor; Dimerization; Immunoprecipitation; Receptor binding; Vasopressin V1b receptor

Indexed keywords

1 [5 CHLORO 1 (2,4 DIMETHOXYLPHENYLSULFONYL) 2,3 DIHYDRO 3 (2 METHOXYPHENYL) 2 OXO 1H INDOL 3 YL] 4 HYDROXY N,N DIMETHYL 2 PYRROLIDINECARBOXAMIDE; 8 (2,4 DICHLOROPHENYL) 4 [2 METHOXY 1 (METHOXYMETHYL)ETHYLAMINO] 2,7 DIMETHYLPYRAZOLO[1,5 A][1,3,5]TRIAZINE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; RENILLA LUCIFERIN 2 MONOOXYGENASE; VASOPRESSIN V1B RECEPTOR; YELLOW FLUORESCENT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; DIMERIZATION; GENETIC TRANSFECTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOPRECIPITATION; IN VITRO STUDY; INCUBATION TIME; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY;

ANIMALS; CHO CELLS; CORTICOTROPIN-RELEASING HORMONE; CRICETINAE; CRICETULUS; DIMERIZATION; HUMANS; PROTEIN BINDING; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, VASOPRESSIN; RECOMBINANT FUSION PROTEINS; TRANSFECTION; VASOPRESSINS;

RENILLA LUCIFERASE;

EID: 34248524346     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-006-9135-8     Document Type: Article

References (51)

1. AbdAlla, S., Lother, H., and Quitterer, U. (2000). AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature 407:94-98.
2. Abou-Samra, A. B., Harwood, J. P., Manganiello, V. C., Catt, K. J., and Aguilera, G. (1987). Phorbol 12-myristate 13-acetate and vasopressin potentiate the effect of corticotropin-releasing factor on cyclic AMP production in rat anterior pituitary cells: Mechanisms of action. J. Biol. Chem. 262:1129-1136.
3. Aguilera, G. (1994). Regulation of pituitary ACTH secretion during chronic stress. Front. Neuroendocrinol. 15:321-350.
4. Aguilera, G., Pham, Q., and Rabadan-Diehl, C. (1994). Regulation of pituitary vasopressin receptors during chronic stress: Relationship to corticotroph responsiveness. J. Neuroendocrinol. 6:299-304.
5. Ayoub, M. A., Couturier, C., Lucas-Meunier, E., Angers, S., Fossier, P., Bouvier, M., and Jockers, R. (2002). Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer. J. Biol. Chem. 277:21522-21528.
6. Berrada, K., Plesnicher, C. L., Luo, X., and Thibonnier, M. (2000). Dynamic interaction of human vasopressin/oxytocin receptor subtypes with G protein-coupled receptor kinases and protein kinase C after agonist stimulation. J. Biol. Chem. 275:27229-27237.
7. Bilezikjian, L. M., Blount, A. L., and Vale, W. W. (1987). The cellular actions of vasopressin on corticotrophs of the anterior pituitary: Resistance to glucocorticoid action. Mol. Endocrinol. 1:451-458.
8. Breit, A., Lagace, M., and Bouvierm, M. (2004). Hetero-oligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties. J. Biol. Chem. 279:28756-28765.
9. Bulenger, S., Marullo, S., and Bouvier, M. (2005). Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation. Trends Pharmacol. Sci. 26:131-137.
10. Calver, A. R., Robbins, M. J., Cosio, C., Rice, S. Q., Babbs, A. J., Hirst, W. D., Boyfield, I., Wood, M. D., Russell, R. B., Price, G. W., Couve, A., Moss, S. J., and Pangalos, M. N. (2001). The C-terminal domains of the GABA(b) receptor subunits mediate intracellular trafficking but are not required for receptor signaling. J. Neurosci. 21:1203-1210.
11. Castro, M. G., Morrisonm, E., Perone, M. J., Brown, O. A., Murray, C. A., Ahmed, I., Perkins, A. V., Europe-Finner, G., Lowenstein, P. R., and Linton, E. A. (1996). Corticotrophin-releasing hormone receptor type 1: Generation and characterization of polyclonal antipeptide antibodies and their localization in pituitary cells and cortical neurones in vitro. J. Neuroendocrinol. 8:521-531.
12. Childs, G. V., and Unabia, G. (1989). Activation of protein kinase C and L calcium channels enhances binding of biotinylated corticotropin-releasing hormone by anterior pituitary corticotropes. Mol. Endocrinol. 3:117-126.
13. Childs, G. V., Westlund, K. N., and Unabia, G. (1989). Characterization of anterior pituitary target cells for arginine vasopressin: including cells that store adrenocorticotropin, thyrotropin-beta, and both hormones. Endocrinology 125:554-559.
14. Cvejic, S., and Devi, L. (1997). Dimerization of the delta opioid receptor: Implication for a role in receptor internalization. J. Biol. Chem. 272:26959-26964.
15. Flores, M., Carvallo, P., and Aguilera, G. (1990). Physicochemical characterization of corticotrophin releasing factor receptor in rat pituitary and brain. Life Sci. 47:2035-2040.
16. George, S. R., Fan, T., Xie, Z., Tse, R., Tam, V., Varghese, G., and O'Dowd, B. F. (2000). Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties. J. Biol. Chem. 275:26128-26135.
17. Gillies, G. E., Linton, E. A., and Lowry, P. J. (1982). Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin. Nature 299:355-357.
18. Gines, S., Hillion, J., Torvinen, M., Le Crom, S., Casado, V., Canela, E. I., Rondin, S., Lew, J. Y., Watson, S., Zoli, M., Agnati, L. F., Verniera, P., Lluis, C., Ferre, S., Fuxe, K., and Franco, R. (2000). Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes. Proc. Natl. Acad. Sci. USA. 97:8606-8611.
19. Gomes, I., Jordan, B. A., Gupta, A., Rios, C., Trapaidze, N., and Devi, L. A. (2001). G protein coupled receptor dimerization: implications in modulating receptor function. J. Mol. Med. 79:226-242.
20. Green, J. L., Figueroa, J. P., Massman, G. A., Schwartz, J., and Rose, J. C. (2000). Corticotropin-releasing hormone type I receptor messenger ribonucleic acid and protein levels in the ovine fetal pituitary: Ontogeny and effect of chronic cortisol administration. Endocrinology 141:2870-2876.
21. Grigoriadis, D. E., and De Souza, E. B. (1988). The brain corticotropin-releasing factor (CRF) receptor is of lower apparent molecular weight than the CRF receptor in anterior pituitary. Evidence from chemical cross-linking studies. J. Biol. Chem. 263:10927-10931.
22. Hague, C., Uberti, M. A., Chen, Z., Hall, R. A., and Minneman, K. P. (2004). Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors. J. Biol. Chem. 279:15541-15549.
23. Hanyaloglu, A. C., Seeber, R. M., Kohout, T. A., Lefkowitz, R. J., and Eidne, K. A. (2002). Homo-and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2. J. Biol. Chem. 277:50422-50430.
24. Hebert, T. E., Moffett, S., Morello, J. P., Loisel, T. P., Bichet, D. G., Barret, C., and Bouvier, M. (1996). A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. J. Biol. Chem. 271:16384-16392.
25. Jia, L. G., Canny, B. J., Orth, D. N., and Leong, D. A. (1991). Distinct classes of corticotropes mediate corticotropin-releasing hormone- and arginine vasopressin-stimulated adrenocorticotropin release. Endocrinology 128:197-203.
26. Jordan, B. A., Cvejic, S., and Devi, L. (2000). Opioids and their complicated receptor complexes. Neuropsychopharmacology 23:S5-S18.
27. Kaupmann, K., Malitschek, B., Schuler, V., Heid, J., Froestl, W., Beck, P., Mosbacher, J., Bischoff, S., Kulik, A., Shigemoto, R., Karschin, A., and Bettler, B. (1998). GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature 396:683-687.
28. Konig, M., Mahan, L. C., Marsg, J. W., Fink, J. S., and Brownstein, M. J. (1991). Method for identifying ligands that bind to cloned Gs- or Gi-coupled receptors. Mol. Cell. Neurosci. 2:331-337.
29. Kraetke, O., Wiesner, B., Eichhorst, J., Furkert, J., Bienert, M., and Beyermann, M. (2005). Dimerization of corticotropin-releasing factor receptor type 1 is not coupled to ligand binding. J. Recept. Signal Transduct. Res. 25:251-276.
30. Kroeger, K. M., Hanyaloglu, A. C., Seeber, R. M., Miles, L. E., and Eidne, K. A. (2001). Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor. Detection in living cells using bioluminescence resonance energy transfer. J. Biol. Chem. 276:12736-12743.
31. Kroeger, K. M., Pfleger, K. D., and Eidne, K. A. (2003). G-protein receptor oligomerization in neuroendocrine pathways. Front. Neuroendocrinol. 24:254-278.
32. Liu, J. P., Engler, D., Funder, J. W., and Robinson, P. J. (1992). Evidence that the stimulation by arginine vasopressin of the release of adrenocorticotropin from the ovine anterior pituitary involves the activation of protein kinase C. Mol. Cell. Endocrinol. 87:35-47.
33. Lolait, S. J., O'Carroll, A. M., Mahan, L. C., Felder, C. C., Button, D. C., Young, W. S., 3rd, Mezey, E., and Brownstein, M. J. (1995). Extrapituitary expression of the rat V1b vasopressin receptor gene. Proc. Natl. Acad. Sci. USA. 92:6783-6787.
34. Nelson, G., Chandrashekar, J., Hoon, M. A., Feng, L., Zhao, G., Ryba, N. J., and Zuker, C. S. (2002). An amino-acid taste receptor. Nature 416:199-202.
35. North, W. G., Fay, M. J., and Du, J. (1999). MCF-7 breast cancer cells express normal forms of all vasopressin receptors plus an abnormal V2R. Peptides 20:837-842.
36. Patel, R. C., Kumar, U., Lamb, D. C., Eid, J. S., Rocheville, M., Grant, M., Rani, A., Hazlett, T., Patel, S. C., Gratton, E., and Patel, Y. C. (2002). Ligand binding to somatostatin receptors induces receptorspecific oligomer formation in live cells. Proc. Natl. Acad. Sci. USA. 99:3294-3299.
37. Pfeiffer, M., Koch, T., Schroder, H., Laugsch, M., Hollt, V., and Schulz, S. (2002). Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. J. Biol. Chem. 277:19762-19772.
38. Robert, J., Auzan, C., Ventura, M. A., and Clauser, E. (2005). Mechanisms of cell-surface rerouting of an ER-retained mutant of the vasopressin V1b/V3 receptor by a pharmacological chaperone. J. Biol. Chem. 280:2300-2308.
39. Rocheville, M., Lange, D. C., Kumar, U., Patel, S. C., Patel, R. C., and Patel, Y. C. (2000a). Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science 288:154-157.
40. Rocheville, M., Lange, D. C., Kumar, U., Sasi, R., Patel, R. C., and Patel, Y. C. (2000b). Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers. J. Biol. Chem. 275:7862-7869.
41. Salahpour, A., Angers, S., and Bouvier, M. (2000). Functional significance of oligomerization of Gprotein-coupled receptors. Trends Endocrinol. Metab. 11:163-168.
42. Sydow, S., Radulovic, J., Dautzenberg, F. M., and Spiess, J. (1997). Structure-function relationship of different domains of the rat corticotropin-releasing factor receptor. Mol. Brain Res. 52:182-193.
43. Terrillon, S., Barberis, C., and Bouvier, M. (2004). Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns. Proc. Natl. Acad. Sci. USA. 101:1548-1553.
44. Terrillon, S., Durroux, T., Mouillac B., Breit, A., Ayoub, M. A., Taulan, M., Jockers, R., Barberis, C., and Bouvier, M. (2003). Oxytocin and vasopressin V1a and V2 receptors form constitutive homoand heterodimers during biosynthesis. Mol. Endocrinol. 17:677-691.
45. van de Pavert, S. A., Clarke, I. J., Rao, A., Vrana, K. E., and Schwartz, J. (1997). Effects of vasopressin and elimination of corticotropin-releasing hormone-target cells on pro-opiomelanocortin mRNA levels and adrenocorticotropin secretion in ovine anterior pituitary cells. J. Endocrinol. 154:139-147.
46. White, J. H., Wise, A., Main, M. J., Green, A., Fraser, N. J., Disney, G. H., Barnes, A. A., Emson, P., Foord, S. M., and Marshall, F. H. (1998). Heterodimerization is required for the formation of a functional GABA(B) receptor. Nature 396:679-682.
47. Xu, G., Rabadan-Diehl, C., Nikodemova, M., Wynn, P., Spiess, J., and Aguilera, G. (2001). Inhibition of corticotropin releasing hormone type-1 receptor translation by an upstream AUG triplet in the 5′ untranslated region. Mol. Pharmacol. 59:485-492.
48. Young, S. F., Smith, J. L., Figueroa, J. P., and Rose, J. C. (2003). Ontogeny and effect of cortisol on vasopressin-1b receptor expression in anterior pituitaries of fetal sheep. AJP - Regul. Integr. Comp. Physiol. 284:R51-R56.
49. Zeng, F., and Wess, J. (2000). Molecular aspects of muscarinic receptor dimerization. Neuropsychopharmacology 23:S19-S31.
50. Zhu, C., Cook, L. B., and Hinkle, P. M. (2002). Dimerization and phosphorylation of thyrotropinreleasing hormone receptors are modulated by agonist stimulation. J. Biol. Chem. 277:28228-28237.
51. Zhu, W., Zeng, X., Zheng, M., and Xiao, R. P. (2005). Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circ. Res. 97:244-251.