-
1
-
-
0026592867
-
Identification of intramolecular interactions in adrenergic receptors
-
Suryanarayana, S., Von Zastrow, M. & Kobilka, B. K. Identification of intramolecular interactions in adrenergic receptors. J. Biol. Chem. 267, 21991-21994 (1992).
-
(1992)
J. Biol. Chem. 267
, pp. 21991-21994
-
-
Suryanarayana, S.1
Von Zastrow, M.2
Kobilka, B.K.3
-
2
-
-
0033118334
-
Molecular tinkering of G protein- coupled receptors: An evolutionary success
-
Bockaert, J. & Pin, J. P. Molecular tinkering of G protein- coupled receptors: an evolutionary success. EMBO J. 18, 1723-1729 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 1723-1729
-
-
Bockaert, J.1
Pin, J.P.2
-
3
-
-
0028973270
-
Dual effect of β-adrenergic receptors on mitogen-activated protein kinase
-
Crespo, P, Cachero, T. G., Xu, N. & Gutkind, J. S. Dual effect of β-adrenergic receptors on mitogen-activated protein kinase. J. Biol. Chem. 270, 25259-25265 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25259-25265
-
-
Crespo, P.1
Cachero, T.G.2
Xu, N.3
Gutkind, J.S.4
-
4
-
-
0030065777
-
Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy
-
Bogoyevitch, M. A. et al. Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy. Biochem. J. 314, 115-121 (1996).
-
(1996)
Biochem. J.
, vol.314
, pp. 115-121
-
-
Bogoyevitch, M.A.1
-
5
-
-
0030784775
-
Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. Involvement of Gi and Gq/11 subunits
-
Yamamoto, J., Nagao, M., Kaziro, Y. & Itoh, H. Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. Involvement of Gi and Gq/11 subunits. J. Biol. Chem. 272, 27771-27777 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27771-27777
-
-
Yamamoto, J.1
Nagao, M.2
Kaziro, Y.3
Itoh, H.4
-
6
-
-
0032544233
-
Differential coupling of α1-, α2-, and β-adrenergic receptors to mitogen-activated protein kinase pathways and differentiation in transfected PC12 cells
-
Williams, N. G., Zhong, H. & Minneman, K. P. Differential coupling of α1-, α2-, and β-adrenergic receptors to mitogen-activated protein kinase pathways and differentiation in transfected PC12 cells. J. Biol. Chem. 273, 24624-24632 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 24624-24632
-
-
Williams, N.G.1
Zhong, H.2
Minneman, K.P.3
-
7
-
-
0033017879
-
Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human β-3 adrenergic receptor: New pharmacological profile and mechanism of activation
-
Gerhardt, C. C., Gros, J., Strosberg, A. D. & Issad, T. Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human β-3 adrenergic receptor: new pharmacological profile and mechanism of activation. Mol. Pharmacol. 55, 255-262 (1999).
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 255-262
-
-
Gerhardt, C.C.1
Gros, J.2
Strosberg, A.D.3
Issad, T.4
-
8
-
-
0033596981
-
The β-3 adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism
-
Soeder, K. J. et al. The β-3 adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism. J. Biol. Chem. 274, 12017-12022 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12017-12022
-
-
Soeder, K.J.1
-
9
-
-
0028977847
-
Receptor-tyrosine-kinase- and Gβγ- mediated MAP kinase activation by a common signalling pathway
-
van Biesen, T. et al. Receptor-tyrosine-kinase- and Gβγ- mediated MAP kinase activation by a common signalling pathway. Nature 376, 781-784 (1995).
-
(1995)
Nature
, vol.376
, pp. 781-784
-
-
Van Biesen, T.1
-
10
-
-
0033515118
-
Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy
-
s and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy. J. Biol. Chem. 274, 9760-9770 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9760-9770
-
-
Zou, Y.1
-
11
-
-
0030614911
-
Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation
-
Luttrell, L. M., Della, R. G., van Biesen, T, Luttrell, D. K. & Lefkowitz, R. J. Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J. Biol. Chem. 272, 4637-4644 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4637-4644
-
-
Luttrell, L.M.1
Della, R.G.2
Van Biesen, T.3
Luttrell, D.K.4
Lefkowitz, R.J.5
-
12
-
-
0033613938
-
Beta-arrestin-dependent formation of β-2- adrenergic receptor-Src protein kinase complexes
-
Luttrell, L. et al. Beta-arrestin-dependent formation of β-2- adrenergic receptor-Src protein kinase complexes. Science 283, 655-661 (1999).
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.1
-
13
-
-
0032498963
-
The β-2 adrenergic receptor interacts with the Na/H-exchanger regulatory factor to control NA/H exchange
-
Hall, R. A. et al. The β-2 adrenergic receptor interacts with the Na/H-exchanger regulatory factor to control NA/H exchange. Nature 329, 626-630 (1998).
-
(1998)
Nature
, vol.329
, pp. 626-630
-
-
Hall, R.A.1
-
14
-
-
2642641315
-
The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor
-
Mellado, M. et al. The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor. J. Immunol. 161, 805-813 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 805-813
-
-
Mellado, M.1
-
15
-
-
0030874924
-
Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor
-
Ali, M. S. et al. Dependence on the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the angiotensin II AT1 receptor. J. Biol. Chem. 272, 23382-23388 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23382-23388
-
-
Ali, M.S.1
-
16
-
-
0029083945
-
Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors
-
Wreggett, K. A. & Wells, J. W. Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. J. Biol. Chem. 270, 22488-22499 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22488-22499
-
-
Wreggett, K.A.1
Wells, J.W.2
-
17
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin, C. H. Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223 (1995).
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.H.1
-
18
-
-
0016712156
-
Beta- adrenergic receptors: Evidence for negative cooperativity
-
Limbird, L. E., Meyts, P. D. & Lefkowitz, R. J. Beta- adrenergic receptors: evidence for negative cooperativity. Biochem. Biophys. Res. Commun. 64, 1160-1168 (1975).
-
(1975)
Biochem. Biophys. Res. Commun.
, vol.64
, pp. 1160-1168
-
-
Limbird, L.E.1
Meyts, P.D.2
Lefkowitz, R.J.3
-
19
-
-
0025924673
-
Evidence for paired M2 muscarinic receptors
-
Potter, L. T. et al. Evidence for paired M2 muscarinic receptors. Mol. Pharmacol. 39, 211-221 (1991).
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 211-221
-
-
Potter, L.T.1
-
20
-
-
0017190266
-
Negative cooperativity among β-adrenergic receptors in frog erythrocyte membranes
-
Limbird, L. E. & Lefkowitz, R. J. Negative cooperativity among β-adrenergic receptors in frog erythrocyte membranes. J. Biol. Chem. 251, 5007-5014 (1976).
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 5007-5014
-
-
Limbird, L.E.1
Lefkowitz, R.J.2
-
21
-
-
0021824455
-
Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analysed by computer-assisted curve fitting
-
Mattera, R., Pitts, B. J., Entman, M. L. & Birnbaumer, L. Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analysed by computer-assisted curve fitting. J. Biol. Chem. 260, 7410-7421 (1985).
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 7410-7421
-
-
Mattera, R.1
Pitts, B.J.2
Entman, M.L.3
Birnbaumer, L.4
-
22
-
-
0028007135
-
A kinetic model for oxotremorine M binding to recombinant porcine m2 muscarinic receptors expressed in Chinese hamster ovary cells
-
Hirschberg, B. T. & Schimerlik, M. I. A kinetic model for oxotremorine M binding to recombinant porcine m2 muscarinic receptors expressed in Chinese hamster ovary cells. J. Biol. Chem. 269, 26127-26135 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26127-26135
-
-
Hirschberg, B.T.1
Schimerlik, M.I.2
-
23
-
-
0026940042
-
The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography
-
Seeman, P. et al. The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography. Eur. J. Pharmacol. 227, 139-146 (1992).
-
(1992)
Eur. J. Pharmacol.
, vol.227
, pp. 139-146
-
-
Seeman, P.1
-
24
-
-
0020666568
-
-
Avissar, S., Amitai, G. & Sokolovsky, M. Oligomeric structure of muscarinic receptors is shown by photoaffinity labeling: subunit assembly may explain high- and low-affinity agonist states. Proc. Natl Acad. Sci. USA 80, 156-159.
-
-
-
Avissar, S.1
Amitai, G.2
Sokolovsky, M.3
-
25
-
-
0020261813
-
The size of the mammalian lung β-2-adrenergic receptor as determined by target size analysis and immunoaffinity chromatography
-
Fraser, C. M. & Venter, J. C. The size of the mammalian lung β-2-adrenergic receptor as determined by target size analysis and immunoaffinity chromatography. Biochem. Biophys. Res. Commun. 109, 21-29 (1982).
-
(1982)
Biochem. Biophys. Res. Commun.
, vol.109
, pp. 21-29
-
-
Fraser, C.M.1
Venter, J.C.2
-
26
-
-
0021047376
-
Molecular size of the human platelet a2-adrenergic receptor as determined by radiation inactivation
-
Venter, J. C., Schaber, J. S., U'Prichard, D. C. & Fraser, C. M. Molecular size of the human platelet a2-adrenergic receptor as determined by radiation inactivation. Biochem. Biophys. Res. Commun. 116, 1070-1075 (1983).
-
(1983)
Biochem. Biophys. Res. Commun.
, vol.116
, pp. 1070-1075
-
-
Venter, J.C.1
Schaber, J.S.2
U'prichard, D.C.3
Fraser, C.M.4
-
27
-
-
0021738223
-
Alpha 1-adrenergic receptor structure
-
Venter, J. C., Horne, P., Eddy, B., Greguski, R. & Fraser, C. M. Alpha 1-adrenergic receptor structure. Mol. Pharmacol. 26, 196-205 (1984).
-
(1984)
Mol. Pharmacol.
, vol.26
, pp. 196-205
-
-
Venter, J.C.1
Horne, P.2
Eddy, B.3
Greguski, R.4
Fraser, C.M.5
-
28
-
-
0021647243
-
Incorporation of radiolabeled amino acids into protein subunits of the rat leydig cell gonadotropin receptor: Application to the study of receptor structure and turnover
-
Crine, P., Aubry, M. & Potier, M. Incorporation of radiolabeled amino acids into protein subunits of the rat leydig cell gonadotropin receptor: application to the study of receptor structure and turnover. Ann. NY Acad. Sci. 438, 224-236 (1984).
-
(1984)
Ann. NY Acad. Sci.
, vol.438
, pp. 224-236
-
-
Crine, P.1
Aubry, M.2
Potier, M.3
-
29
-
-
0021874395
-
Radiation inactivation (Target size analysis) of the gonadotropin-releasing hormone receptor: Evidence for a high molecular weight complex
-
Conn, P. M. & Venter, J. C. Radiation inactivation (target size analysis) of the gonadotropin-releasing hormone receptor: evidence for a high molecular weight complex. Endocrinology 116, 1324-1326 (1985).
-
(1985)
Endocrinology
, vol.116
, pp. 1324-1326
-
-
Conn, P.M.1
Venter, J.C.2
-
30
-
-
0022930135
-
Solubilization and characterization of D2- dopamine receptors in an estrone-induced, prolactin- secreting rat pituitary adenoma
-
Bouvier, C. et al. Solubilization and characterization of D2- dopamine receptors in an estrone-induced, prolactin- secreting rat pituitary adenoma. J. Neurochem. 47, 1653-1660 (1986).
-
(1986)
J. Neurochem.
, vol.47
, pp. 1653-1660
-
-
Bouvier, C.1
-
31
-
-
0022451888
-
Target size of the adenosine R1 receptor
-
Frame, L. T., Yeung, S. M., Venter, J. C. & Cooper, D. M. Target size of the adenosine R1 receptor. Biochem. J. 235, 621-624 (1986).
-
(1986)
Biochem. J.
, vol.235
, pp. 621-624
-
-
Frame, L.T.1
Yeung, S.M.2
Venter, J.C.3
Cooper, D.M.4
-
32
-
-
0021165094
-
The hepatic glucagon receptor. Solubilization, characterization, and development of an affinity adsorption assay for the soluble receptor
-
Herberg, J. T., Codina, J., Rich, K. A., Rojas, F. J. & Iyengar, R. The hepatic glucagon receptor. Solubilization, characterization, and development of an affinity adsorption assay for the soluble receptor. J. Biol. Chem. 259, 9285-9294 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 9285-9294
-
-
Herberg, J.T.1
Codina, J.2
Rich, K.A.3
Rojas, F.J.4
Iyengar, R.5
-
33
-
-
0022536212
-
Physical properties of the purified cardiac muscarinic acetylcholine receptor
-
Peterson, G. L., Rosenbaum, L. C., Broderick, D. J. & Schimerlick, M. I. Physical properties of the purified cardiac muscarinic acetylcholine receptor. Biochemistry 25, 3189-3202 (1986).
-
(1986)
Biochemistry
, vol.25
, pp. 3189-3202
-
-
Peterson, G.L.1
Rosenbaum, L.C.2
Broderick, D.J.3
Schimerlick, M.I.4
-
34
-
-
0027467848
-
Co-expression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular 'cross-talk' between G-protein-linked receptors
-
Maggio, R., Vogel, Z. & Wess, J. Co-expression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular 'cross-talk' between G-protein-linked receptors. Proc. Natl Acad. Sci. USA 90, 3103-3107 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 3103-3107
-
-
Maggio, R.1
Vogel, Z.2
Wess, J.3
-
35
-
-
0030028756
-
Polar residues in the transmembrane domain of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants
-
Monnot, C. et al. Polar residues in the transmembrane domain of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants. J. Biol. Chem. 271, 1507-1513 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1507-1513
-
-
Monnot, C.1
-
36
-
-
0033020243
-
Intermolecular interactions between dimeric calcium- sensing receptor monomers are important for its normal function
-
Bai, M., Trivedi, S., Kifor, O., Quinn, S. J. & Brown, E. M. Intermolecular interactions between dimeric calcium- sensing receptor monomers are important for its normal function. Proc. Natl Acad. Sci. USA 96, 2834-2839 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 2834-2839
-
-
Bai, M.1
Trivedi, S.2
Kifor, O.3
Quinn, S.J.4
Brown, E.M.5
-
37
-
-
0029761073
-
Expression and characterization of inactivating and activating mutations in the human Ca2+-sensing receptor
-
2+-sensing receptor. J. Biol. Chem. 271, 19537-19545 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19537-19545
-
-
Bai, M.1
-
38
-
-
0032506160
-
Truncated V2 vasopressin receptors as negative regulators of wild-type V2 receptor function
-
Zhu, X. & Wess, J. Truncated V2 vasopressin receptors as negative regulators of wild-type V2 receptor function. Biochemistry 37, 15773-15784 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 15773-15784
-
-
Zhu, X.1
Wess, J.2
-
39
-
-
0030712312
-
Mechanism of transdominant inhibition of CCR5- mediated HIV-1 infection by ccr5delta32
-
Benkirane, M., Jin, D. Y, Chun, R. F., Koup, R. A. & Jeang, K. T. Mechanism of transdominant inhibition of CCR5- mediated HIV-1 infection by ccr5delta32. J. Biol. Chem. 272, 30603-30606 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30603-30606
-
-
Benkirane, M.1
Jin, D.Y.2
Chun, R.F.3
Koup, R.A.4
Jeang, K.T.5
-
40
-
-
0033616765
-
The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2
-
Rodriguez-Frade, J. M. et al. The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2. Proc. Natl Acad. Sci. USA 96, 3628-3633 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 3628-3633
-
-
Rodriguez-Frade, J.M.1
-
41
-
-
0034704906
-
G Protein coupled receptors function as oligomers
-
Overton, M. C. & Blumer, K. J. G Protein coupled receptors function as oligomers in vivo. Curr. Biol. 10, 341-344 (2000).
-
(2000)
In Vivo. Curr. Biol
, vol.10
, pp. 341-344
-
-
Overton, M.C.1
Blumer, K.J.2
-
42
-
-
0029666267
-
A peptide derived from a P2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation
-
Hebert, T. E. et al. A peptide derived from a P2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. J. Biol. Chem. 271, 16384-16392 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16384-16392
-
-
Hebert, T.E.1
-
43
-
-
17444380779
-
Heterodimerization is required for the formation of a functional GABA(B) receptor
-
White, J. H. et al. Heterodimerization is required for the formation of a functional GABA(B) receptor. Nature 396, 679-682 (1998).
-
(1998)
Nature
, vol.396
, pp. 679-682
-
-
White, J.H.1
-
44
-
-
0005169503
-
GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2
-
Jones, K. A. et al. GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2. Nature 396, 674-679 (1998).
-
(1998)
Nature
, vol.396
, pp. 674-679
-
-
Jones, K.A.1
-
45
-
-
0032542382
-
GABA(B)-receptor subtypes assemble into functional heteromeric complexes
-
Kaupmann, K. et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature 396, 683-687 (1998).
-
(1998)
Nature
, vol.396
, pp. 683-687
-
-
Kaupmann, K.1
-
46
-
-
0029903640
-
Metabotropic glutamate receptor 5 is a disulfide-linked dimer
-
Romano, C., Yang, W. L. & O'Malley, K. L. Metabotropic glutamate receptor 5 is a disulfide-linked dimer. J. Biol. Chem. 271, 28612-28616 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28612-28616
-
-
Romano, C.1
Yang, W.L.2
O'malley, K.L.3
-
47
-
-
0033578005
-
G-protein-coupled receptor heterodimerization modulates receptor function
-
Jordan, B. A. & Devi, L. A. G-protein-coupled receptor heterodimerization modulates receptor function. Nature 399, 697-700 (1999).
-
(1999)
Nature
, vol.399
, pp. 697-700
-
-
Jordan, B.A.1
Devi, L.A.2
-
48
-
-
0032483541
-
Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells
-
Bai, M., Trivedi, S. & Brown, E. M. Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells. J. Biol. Chem. 273, 23605-23610 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23605-23610
-
-
Bai, M.1
Trivedi, S.2
Brown, E.M.3
-
49
-
-
0033516576
-
Identification and molecular characterization of m3 muscarinic receptor dimers
-
Zeng, F. Y. & Wess, J. Identification and molecular characterization of m3 muscarinic receptor dimers. J. Biol. Chem. 274, 19487-19497 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19487-19497
-
-
Zeng, F.Y.1
Wess, J.2
-
50
-
-
0017251379
-
Subunit structure of human erythrocyte glycophorin A
-
Furthmayr, H. & Marchesi, V. T. Subunit structure of human erythrocyte glycophorin A. Biochemistry 15, 1137-1144 (1976).
-
(1976)
Biochemistry
, vol.15
, pp. 1137-1144
-
-
Furthmayr, H.1
Marchesi, V.T.2
-
51
-
-
0030760634
-
Dimerization of the S-opioid receptor: Implication for a role in receptor internalization
-
Cvejic, S. & Devi, L. A. Dimerization of the S-opioid receptor: implication for a role in receptor internalization. J. Biol. Chem. 272, 26959-26964 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26959-26964
-
-
Cvejic, S.1
Devi, L.A.2
-
52
-
-
0029417184
-
Immunological identification of A1 adenosine receptors in brain cortex
-
Ciruela, F. et al. Immunological identification of A1 adenosine receptors in brain cortex. J. Neurosci. Res. 42, 818-828 (1995).
-
(1995)
J. Neurosci. Res.
, vol.42
, pp. 818-828
-
-
Ciruela, F.1
-
53
-
-
0030567986
-
Dopamine D2 receptor dimers and receptor- blocking peptides
-
Ng, G. Y. et al. Dopamine D2 receptor dimers and receptor- blocking peptides. Biochem. Biophys. Res. Commun. 227, 200-204 (1996).
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.227
, pp. 200-204
-
-
Ng, G.Y.1
-
54
-
-
0034724192
-
Detection of P2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)
-
Angers, S. et al. Detection of P2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc. Natl Acad. Sci. USA 97, 3684-3689 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3684-3689
-
-
Angers, S.1
-
55
-
-
84984761972
-
-
McVey, M. et al. Monitoring receptor oligomerization using time-resolved fluorescence resonance energy transfer and bioluminescence resonance energy transfer: The human S- opioid receptor displays constitutive oligomerization at the cell surface which is not regulated by receptor occupancy. J. Biol. Chem. (in the press).
-
-
-
McVey, M.1
-
56
-
-
84984752835
-
-
Kroeger, K. M., Hanyaloglu, A. C., Seeber, R. M., Miles, L. E. C. & Eidne, K. A. Constitutive and agonist-dependent homo-oligomerizationof the thyrotropin-releasing hormone receptor; detection in living cells using bioluminescence resonance energy transfer. J. Biol. Chem. (in the press).
-
-
-
Kroeger, K.M.1
Hanyaloglu, A.C.2
Seeber, R.M.3
Miles, L.E.C.4
Eidne, K.A.5
-
57
-
-
0034677745
-
Subtypes of the somatostatin receptor assemble as functional homo-and heterodimers
-
Rocheville, M. et al. Subtypes of the somatostatin receptor assemble as functional homo-and heterodimers. J. Biol. Chem. 275, 7862-7869 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7862-7869
-
-
Rocheville, M.1
-
58
-
-
0034522937
-
Luteinizing hormone receptors are self-associated in the plasma membrane
-
Roess, D. A., Horvat, R. D., Munnelly, H. & Barisas, B. G. Luteinizing hormone receptors are self-associated in the plasma membrane. Endocrinology 141, 4518-4523 (2000).
-
(2000)
Endocrinology
, vol.141
, pp. 4518-4523
-
-
Roess, D.A.1
Horvat, R.D.2
Munnelly, H.3
Barisas, B.G.4
-
59
-
-
0003828002
-
-
Leff, P., Marcel Dekker, New York
-
Bond, R. A. & Bouvier, M. Receptor-based Drug Design (ed. Leff, P.) 363-377 (Marcel Dekker, New York, 1998).
-
(1998)
Receptor-Based Drug Design
, pp. 363-377
-
-
Bond, R.A.1
Bouvier, M.2
-
60
-
-
0033582820
-
Identification of a GABAb receptor subunit, gb2, required for functional GABAb receptor activity
-
b receptor subunit, gb2, required for functional GABAb receptor activity. J. Biol. Chem. 274, 7607-7610 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7607-7610
-
-
Ng, G.Y.1
-
61
-
-
0032929331
-
Role of heteromer formation in GABAb receptor function
-
Kuner, R. et al. Role of heteromer formation in GABAb receptor function. Science 283, 74-77 (1999).
-
(1999)
Science
, vol.283
, pp. 74-77
-
-
Kuner, R.1
-
62
-
-
0032500579
-
Intracellular retention of recombinant GABAb receptors
-
Couve, A. et al. Intracellular retention of recombinant GABAb receptors. J. Biol. Chem. 273, 26361-26367 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26361-26367
-
-
Couve, A.1
-
63
-
-
0033667466
-
A trafficking checkpoint controls GABA(B) receptor heterodimerization
-
Margeta-Mitrovic, M., Jan, Y. N. & Jan, L. Y. A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron 27, 97-106 (2000).
-
(2000)
Neuron
, vol.27
, pp. 97-106
-
-
Margeta-Mitrovic, M.1
Jan, Y.N.2
Jan, L.Y.3
-
64
-
-
0034118221
-
Pharmacological chaperones rescue cell- surface expression and function of misfolded V2 vasopressin receptor mutants
-
Morello, J. P et al. Pharmacological chaperones rescue cell- surface expression and function of misfolded V2 vasopressin receptor mutants. J. Clin. Invest. 105, 887-895 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 887-895
-
-
Morello, J.P.1
-
65
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng, H. et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 381, 661-666 (1996).
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
-
66
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson, M. et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382, 722-725 (1996).
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
-
67
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu, R. et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86, 367-377 (1996).
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
-
68
-
-
0033798153
-
The dopamine D3 receptor interacts with itself and the truncated D3 splice variant d3nf: D3-D3nf interaction causes mislocalization of D3 receptors
-
Karpa, K. D., Lin, R., Kabbani, N. & Levenson, R. The dopamine D3 receptor interacts with itself and the truncated D3 splice variant d3nf: D3-D3nf interaction causes mislocalization of D3 receptors. Mol. Pharmacol. 58, 677-683 (2000).
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 677-683
-
-
Karpa, K.D.1
Lin, R.2
Kabbani, N.3
Levenson, R.4
-
69
-
-
0030613635
-
Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells
-
Nimchinsky, E. A., Hof, P. R., Janssen, W. G. M., Morrison, J. H. & Schmauss, C. Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells. J. Biol. Chem. 272, 29229-29237 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29229-29237
-
-
Nimchinsky, E.A.1
Hof, P.R.2
Janssen, W.G.M.3
Morrison, J.H.4
Schmauss, C.5
-
70
-
-
0032515074
-
A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization
-
George, S. R. et al. A transmembrane domain-derived peptide inhibits D1 dopamine receptor function without affecting receptor oligomerization. J. Biol. Chem. 273, 30244-30248 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30244-30248
-
-
George, S.R.1
-
71
-
-
0033916687
-
From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-P2-adrenoceptor antibody behave as antagonists
-
Mijares, A., Lebesgue, D., Wallukat, G. & Hoebeke, J. From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-P2-adrenoceptor antibody behave as antagonists. Mol. Pharmacol. 58, 373-379 (2000).
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 373-379
-
-
Mijares, A.1
Lebesgue, D.2
Wallukat, G.3
Hoebeke, J.4
-
72
-
-
0020328255
-
Conversion of a gonadotropin-releasing hormone antagonist to an agonist
-
Conn, P. M., Rogers, D. C., Stewart, J. M., Niedel, J. & Sheffield, T. Conversion of a gonadotropin-releasing hormone antagonist to an agonist. Nature 296, 653-655 (1982).
-
(1982)
Nature
, vol.296
, pp. 653-655
-
-
Conn, P.M.1
Rogers, D.C.2
Stewart, J.M.3
Niedel, J.4
Sheffield, T.5
-
73
-
-
0022338628
-
Gonadotropin releasing hormone activation is mediated by dimerization of occupied receptors
-
Hazum, E. & Keinan, D. Gonadotropin releasing hormone activation is mediated by dimerization of occupied receptors. Biochem. Biophys. Res. Commun. 133, 449-456 (1985).
-
(1985)
Biochem. Biophys. Res. Commun.
, vol.133
, pp. 449-456
-
-
Hazum, E.1
Keinan, D.2
-
74
-
-
0020438571
-
Luteinizing hormone release from dissociated pituitary cells by dimerization of occupied LHRH receptors
-
Gregory, H., Taylor, C. L. & Hopkins, C. R. Luteinizing hormone release from dissociated pituitary cells by dimerization of occupied LHRH receptors. Nature 300, 269-271 (1982).
-
(1982)
Nature
, vol.300
, pp. 269-271
-
-
Gregory, H.1
Taylor, C.L.2
Hopkins, C.R.3
-
75
-
-
0030198872
-
Synthesis and characterization of bivalent peptide ligands targeted to G-protein-coupled receptors
-
Carrithers, M. D. & Lerner, M. R. Synthesis and characterization of bivalent peptide ligands targeted to G-protein-coupled receptors. Chem. Biol. 3, 537-542 (1996).
-
(1996)
Chem. Biol.
, vol.3
, pp. 537-542
-
-
Carrithers, M.D.1
Lerner, M.R.2
-
76
-
-
0034724420
-
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization
-
Vila-Coro, A. J. et al. HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization. Proc. Natl Acad. Sci. USA 97, 3388-3393 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3388-3393
-
-
Vila-Coro, A.J.1
-
77
-
-
0345299129
-
Characterization and visualization of rat and guinea pig brain κ-opioid receptors: Evidence for κ1 and κ2 opioid receptors
-
Zukin, R. S., Eghbali, M., Olive, D., Unterwald, E. M. & Tempel, A. Characterization and visualization of rat and guinea pig brain κ-opioid receptors: evidence for κ1 and κ2 opioid receptors. Proc. Natl Acad. Sci. USA 85, 4061-4065 (1988).
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 4061-4065
-
-
Zukin, R.S.1
Eghbali, M.2
Olive, D.3
Unterwald, E.M.4
Tempel, A.5
-
78
-
-
0034618268
-
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
-
AbdAlla, S., Lother, H. & Quitterer, U. AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. Nature 407, 94-98 (2000).
-
(2000)
Nature
, vol.407
, pp. 94-98
-
-
Abdalla, S.1
Lother, H.2
Quitterer, U.3
-
79
-
-
0034682445
-
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes
-
Gines, S. et al. Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes. Proc. Natl Acad. Sci. USA 97, 8606-8611 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 8606-8611
-
-
Gines, S.1
-
80
-
-
0034714335
-
Oligomerization of μ- and δ-opioid receptors. Generation of novel functional properties
-
George, S. R. et al. Oligomerization of μ- and δ-opioid receptors. Generation of novel functional properties. J. Biol. Chem. 275, 26128-26135 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26128-26135
-
-
George, S.R.1
-
81
-
-
0034616021
-
Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
-
Rocheville, M. et al. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science 288, 154-157 (2000).
-
(2000)
Science
, vol.288
, pp. 154-157
-
-
Rocheville, M.1
-
82
-
-
0035793079
-
Oligomerization of opioid receptors with P2-adrenergic receptors: A role in trafficking and mitogen-activated protein kinase activation
-
Jordan, B. A., Trapaidze, N., Gomes, I., Nivarthi, R. & Devi, L. A. Oligomerization of opioid receptors with P2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation. Proc. Natl Acad. Sci. USA 98, 343-348 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 343-348
-
-
Jordan, B.A.1
Trapaidze, N.2
Gomes, I.3
Nivarthi, R.4
Devi, L.A.5
-
83
-
-
0033578005
-
G-protein-coupled receptor heterodimerization modulates receptor function
-
Jordan, B. A. & Devi, L. A. G-protein-coupled receptor heterodimerization modulates receptor function. Nature 399, 697-700 (1999).
-
(1999)
Nature
, vol.399
, pp. 697-700
-
-
Jordan, B.A.1
Devi, L.A.2
-
84
-
-
0033516576
-
Identification and molecular characterization of m3 muscarinic receptor dimers
-
Zeng, F. Y. & Wess, J. Identification and molecular characterization of m3 muscarinic receptor dimers. J. Biol. Chem. 274, 19487-19497 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19487-19497
-
-
Zeng, F.Y.1
Wess, J.2
-
85
-
-
84984755140
-
-
Cornea, A., Janovick, J. A., Maya-Nunez, G. & Conn, P. M. Gonadotropin releasing hormone microaggregation: rate monitored by fluorescence resonance energy transfer. J. Biol. Chem. (in the press).
-
-
-
Cornea, A.1
Janovick, J.A.2
Maya-Nunez, G.3
Conn, P.M.4
-
86
-
-
0034718925
-
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor
-
Kunishima, N. et al. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature 407, 971-977 (2000).
-
(2000)
Nature
, vol.407
, pp. 971-977
-
-
Kunishima, N.1
-
87
-
-
0034623081
-
Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1
-
Tsuji, Y. et al. Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1. J. Biol. Chem. 275, 28144-28151 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28144-28151
-
-
Tsuji, Y.1
-
88
-
-
0034602293
-
Cys-140 is critical for metabotropic glutamate receptor-1 dimerization
-
Ray, K. & Hauschild, B. C. Cys-140 is critical for metabotropic glutamate receptor-1 dimerization. J. Biol. Chem. 275, 34245-34251 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34245-34251
-
-
Ray, K.1
Hauschild, B.C.2
-
89
-
-
0035164277
-
Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu(5) dimerization
-
Romano, C. et al. Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu(5) dimerization. Mol. Pharmacol. 59, 46-53 (2001).
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 46-53
-
-
Romano, C.1
-
90
-
-
0348141172
-
The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions
-
Zhang, Z., Sun, S., Quinn, S. J., Brown, E. M. & Bai, M. The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions. J. Biol. Chem. (2000).
-
(2000)
J. Biol. Chem
-
-
Zhang, Z.1
Sun, S.2
Quinn, S.J.3
Brown, E.M.4
Bai, M.5
-
91
-
-
0026686793
-
Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices
-
Lemmon, M. A. et al. Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices. J. Biol. Chem. 267, 7683-7689 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7683-7689
-
-
Lemmon, M.A.1
-
92
-
-
0028235050
-
Specificity and promiscuity in membrane helix interactions
-
Lemmon, M. A. & Engelman, D. M. Specificity and promiscuity in membrane helix interactions. FEBS Lett. 346, 17-20 (1994).
-
(1994)
FEBS Lett
, vol.346
, pp. 17-20
-
-
Lemmon, M.A.1
Engelman, D.M.2
-
93
-
-
0033806215
-
Dimerization and domain swapping in G-protein-coupled receptors. A computational study
-
Gouldson, P. R. et al. Dimerization and domain swapping in G-protein-coupled receptors. A computational study. Neuropsychopharmacology 23, S60-S77 (2000).
-
(2000)
Neuropsychopharmacology
, vol.23
, pp. S60-S77
-
-
Gouldson, P.R.1
-
94
-
-
0035164999
-
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action
-
Ng, G. Y. et al. Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. Mol. Pharmacol. 59, 144-152 (2001).
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 144-152
-
-
Ng, G.Y.1
-
95
-
-
0033524455
-
A bioluminescence resonance energy transfer (BRET) system: Application to interacting circadian clock proteins
-
Xu, Y., Piston, D. W. & Johnson, C. H. A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins. Proc. Natl Acad. Sci. USA 96, 151-156 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 151-156
-
-
Xu, Y.1
Piston, D.W.2
Johnson, C.H.3
-
96
-
-
0001019448
-
Fluorescence techniques: Shedding light on ligand-receptor interactions
-
Hovius, R., Vallotton, P., Wohland, T. & Vogel, H. Fluorescence techniques: shedding light on ligand-receptor interactions. Trends Pharmacol. Sci. 21, 266-273 (2000).
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 266-273
-
-
Hovius, R.1
Vallotton, P.2
Wohland, T.3
Vogel, H.4
-
97
-
-
0027440296
-
A new calcitonin-receptor-like sequence in rat pulmonary blood vessels
-
Njuki, F. et al. A new calcitonin-receptor-like sequence in rat pulmonary blood vessels. Clin. Sci. 85, 385-388 (1993).
-
(1993)
Clin. Sci.
, vol.85
, pp. 385-388
-
-
Njuki, F.1
-
98
-
-
0028872954
-
A human orphan calcitonin receptor-like structure
-
Fluhmann, B., Muff, R., Hunziker, W., Fischer, J. A. & Born, W. A human orphan calcitonin receptor-like structure. Biochem. Biophys. Res. Commun. 206, 341-347 (1995).
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.206
, pp. 341-347
-
-
Fluhmann, B.1
Muff, R.2
Hunziker, W.3
Fischer, J.A.4
Born, W.5
-
99
-
-
0032574982
-
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
-
McLatchie, L. M. et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393, 333-339 (1998).
-
(1998)
Nature
, vol.393
, pp. 333-339
-
-
McLatchie, L.M.1
-
100
-
-
0033039911
-
Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product
-
Christopoulos, G. et al. Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product. Mol. Pharmacol. 56, 235-242 (1999).
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 235-242
-
-
Christopoulos, G.1
-
101
-
-
0032076851
-
Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein
-
Dwyer, N. D., Troemel, E. R., Sengupta, P & Bargmann, C. I. Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein. Cell 93, 455-466 (1998).
-
(1998)
Cell
, vol.93
, pp. 455-466
-
-
Dwyer, N.D.1
Troemel, E.R.2
Sengupta, P.3
Bargmann, C.I.4
-
102
-
-
0034688225
-
Direct protein-protein coupling enables crosstalk between dopamine D5 and y-aminobutyric acid A receptors
-
Liu, F. et al. Direct protein-protein coupling enables crosstalk between dopamine D5 and y-aminobutyric acid A receptors. Nature 403, 274-280 (2000).
-
(2000)
Nature
, vol.403
, pp. 274-280
-
-
Liu, F.1
-
103
-
-
0029560902
-
Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain
-
Bergson, C. et al. Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain. J. Neurosci. 15, 7821-7836 (1995).
-
(1995)
J. Neurosci.
, vol.15
, pp. 7821-7836
-
-
Bergson, C.1
|