메뉴 건너뛰기




Volumn 34, Issue 6, 2010, Pages 925-951

How Saccharomyces cerevisiae copeswith toxicmetals and metalloids

Author keywords

Arsenic; Cadmium; Chromium; Metal detoxification; Metal toxicity; Selenium

Indexed keywords

ANTIMONY; ARSENIC; ARSENIC TRIOXIDE; CADMIUM; CHROMIC ACID; CHROMIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MERCURY; METAL; METAL DERIVATIVE; METALLOID; MOLYBDIC ACID; RIBOSOME PROTEIN; SELENATE; SELENIUM; SULFUR; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 77957803530     PISSN: 01686445     EISSN: 15746976     Source Type: Journal    
DOI: 10.1111/j.1574-6976.2010.00217.x     Document Type: Review
Times cited : (242)

References (294)
  • 1
    • 40949115926 scopus 로고    scopus 로고
    • Transmembrane topology of the Acr3 family arsenite transporter from Bacillus subtilis
    • Aaltonen EK & Silow M. (2008) Transmembrane topology of the Acr3 family arsenite transporter from Bacillus subtilis. Biochim Biophys Acta 1778: 963-973.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 963-973
    • Aaltonen, E.K.1    Silow, M.2
  • 2
    • 57649114599 scopus 로고    scopus 로고
    • Expressional control of a cadmiumtransporting P1B-type ATPase by a metal sensing degradation signal
    • Adle DJ & Lee J. (2008) Expressional control of a cadmiumtransporting P1B-type ATPase by a metal sensing degradation signal. J Biol Chem 283: 31460-31468.
    • (2008) J Biol Chem , vol.283 , pp. 31460-31468
    • Adle, D.J.1    Lee, J.2
  • 3
    • 33847697804 scopus 로고    scopus 로고
    • A cadmiumtransporting P1B-type ATPase in yeast Saccharomyces cerevisiae
    • Adle DJ, Sinani D, Kim H & Lee J. (2007) A cadmiumtransporting P1B-type ATPase in yeast Saccharomyces cerevisiae. J Biol Chem 282: 947-955.
    • (2007) J Biol Chem , vol.282 , pp. 947-955
    • Adle, D.J.1    Sinani, D.2    Kim, H.3    Lee, J.4
  • 4
    • 67649854416 scopus 로고    scopus 로고
    • Cadmiummediated rescue from ER-associated degradation induces expression of its exporter
    • Adle DJ, Wei W, Smith N, Bies JJ & Lee J. (2009) Cadmiummediated rescue from ER-associated degradation induces expression of its exporter. P Natl Acad Sci USA 106: 10189-10194.
    • (2009) P Natl Acad Sci USA , vol.106 , pp. 10189-10194
    • Adle, D.J.1    Wei, W.2    Smith, N.3    Bies, J.J.4    Lee, J.5
  • 5
    • 0032891070 scopus 로고    scopus 로고
    • The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans
    • Alarco AM & Raymond M. (1999) The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans. J Bacteriol 181: 700-708.
    • (1999) J Bacteriol , vol.181 , pp. 700-708
    • Alarco, A.M.1    Raymond, M.2
  • 6
    • 0029267021 scopus 로고
    • Uptake of chromate in human red blood cells and isolated rat liver cells: the role of the anion carrier
    • Alexander J & Aaseth J. (1995) Uptake of chromate in human red blood cells and isolated rat liver cells: the role of the anion carrier. Analyst 120: 931-933.
    • (1995) Analyst , vol.120 , pp. 931-933
    • Alexander, J.1    Aaseth, J.2
  • 8
    • 3042733910 scopus 로고    scopus 로고
    • 2+ in Schizosaccharomyces pombe through amino acid-coded mass tagging and liquid chromatography tandem mass spectrometry
    • 2+ in Schizosaccharomyces pombe through amino acid-coded mass tagging and liquid chromatography tandem mass spectrometry. Mol Cell Proteomics 3: 596-607.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 596-607
    • Bae, W.1    Chen, X.2
  • 9
    • 14544292921 scopus 로고    scopus 로고
    • Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2-MSH6 complex
    • Banerjee S & Flores-Rozas H. (2005) Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2-MSH6 complex. Nucleic Acids Res 33: 1410-1419.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1410-1419
    • Banerjee, S.1    Flores-Rozas, H.2
  • 12
    • 0033540030 scopus 로고    scopus 로고
    • The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
    • Beck T & Hall MN. (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402: 689-692.
    • (1999) Nature , vol.402 , pp. 689-692
    • Beck, T.1    Hall, M.N.2
  • 13
    • 73649121261 scopus 로고    scopus 로고
    • Identification of positive regulators of the yeast Fps1 glycerol channel
    • Beese SE, Negishi T & Levin DE. (2009) Identification of positive regulators of the yeast Fps1 glycerol channel. PLoS Genet 5: e1000738.
    • (2009) PLoS Genet , vol.5
    • Beese, S.E.1    Negishi, T.2    Levin, D.E.3
  • 14
    • 48749096008 scopus 로고    scopus 로고
    • Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms
    • Beyersmann D & Hartwig A. (2008) Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms. Arch Toxicol 82: 493-512.
    • (2008) Arch Toxicol , vol.82 , pp. 493-512
    • Beyersmann, D.1    Hartwig, A.2
  • 16
    • 4644229317 scopus 로고    scopus 로고
    • Rck1 and Rck2 MAPKAP kinases and the HOG pathway are required for oxidative stress resistance
    • Bilsland E, Molin C, Swaminathan S, Ramne A & Sunnerhagen P. (2004) Rck1 and Rck2 MAPKAP kinases and the HOG pathway are required for oxidative stress resistance. Mol Microbiol 53: 1743-1756.
    • (2004) Mol Microbiol , vol.53 , pp. 1743-1756
    • Bilsland, E.1    Molin, C.2    Swaminathan, S.3    Ramne, A.4    Sunnerhagen, P.5
  • 17
    • 0032476584 scopus 로고    scopus 로고
    • Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA
    • Blaiseau PL &Thomas D. (1998) Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA. EMBO J 17: 6327-6336.
    • (1998) EMBO J , vol.17 , pp. 6327-6336
    • Blaiseau, P.L.1    Thomas, D.2
  • 18
    • 0030979616 scopus 로고    scopus 로고
    • Met31p and Met32p, two related zinc finger proteins, are involved in transcriptional regulation of yeast sulfur amino acid metabolism
    • Blaiseau PL, Isnard AD, Surdin-Kerjan Y & Thomas D. (1997) Met31p and Met32p, two related zinc finger proteins, are involved in transcriptional regulation of yeast sulfur amino acid metabolism. Mol Cell Biol 17: 3640-3648.
    • (1997) Mol Cell Biol , vol.17 , pp. 3640-3648
    • Blaiseau, P.L.1    Isnard, A.D.2    Surdin-Kerjan, Y.3    Thomas, D.4
  • 19
    • 0031978709 scopus 로고    scopus 로고
    • Arsenical-induced transcriptional activation of the yeast Saccharomyces cerevisiae ACR2 and ACR3 genes requires the presence of the ACR1 gene product
    • Bobrowicz P & Ulaszewski S. (1998) Arsenical-induced transcriptional activation of the yeast Saccharomyces cerevisiae ACR2 and ACR3 genes requires the presence of the ACR1 gene product. Cell Mol Biol Lett 3: 13-20.
    • (1998) Cell Mol Biol Lett , vol.3 , pp. 13-20
    • Bobrowicz, P.1    Ulaszewski, S.2
  • 20
    • 0030836016 scopus 로고    scopus 로고
    • Isolation of three contiguous genes, ACR1, ACR2 and ACR3, involved in resistance to arsenic compounds in the yeast Saccharomyces cerevisiae
    • Bobrowicz P, Wysocki R, Owsianik G, Goffeau A & Ulaszewski S. (1997) Isolation of three contiguous genes, ACR1, ACR2 and ACR3, involved in resistance to arsenic compounds in the yeast Saccharomyces cerevisiae. Yeast 13: 819-828.
    • (1997) Yeast , vol.13 , pp. 819-828
    • Bobrowicz, P.1    Wysocki, R.2    Owsianik, G.3    Goffeau, A.4    Ulaszewski, S.5
  • 21
    • 57349167530 scopus 로고    scopus 로고
    • Insight into the role of HOG pathway components Ssk2p, Pbs2p, and Hog1p in the opportunistic yeast Candida lusitaniae
    • Boisnard S, Ruprich-Robert G, Florent M, Da Silva B, Chapeland-Leclerc F & Papon N. (2008) Insight into the role of HOG pathway components Ssk2p, Pbs2p, and Hog1p in the opportunistic yeast Candida lusitaniae. Eukaryot Cell 7: 2179-2183.
    • (2008) Eukaryot Cell , vol.7 , pp. 2179-2183
    • Boisnard, S.1    Ruprich-Robert, G.2    Florent, M.3    Da Silva, B.4    Chapeland-Leclerc, F.5    Papon, N.6
  • 22
    • 0037119369 scopus 로고    scopus 로고
    • Surplus zinc is handled by Zym1 metallothionein and Zhf endoplasmic reticulum transporter in Schizosaccharomyces pombe
    • Borrelly GP, Harrison MD, Robinson AK, Cox SG, Robinson NJ & Whitehall SK. (2002) Surplus zinc is handled by Zym1 metallothionein and Zhf endoplasmic reticulum transporter in Schizosaccharomyces pombe. J Biol Chem 277: 30394-30400.
    • (2002) J Biol Chem , vol.277 , pp. 30394-30400
    • Borrelly, G.P.1    Harrison, M.D.2    Robinson, A.K.3    Cox, S.G.4    Robinson, N.J.5    Whitehall, S.K.6
  • 23
    • 0034892670 scopus 로고    scopus 로고
    • Yap1 overproduction restores arsenite resistance to the ABCtransporter deficient mutant ycf1 by activating ACR3 expression
    • Bouganim N, David J, Wysocki R & Ramotar D. (2001) Yap1 overproduction restores arsenite resistance to the ABCtransporter deficient mutant ycf1 by activating ACR3 expression. Biochem Cell Biol 79: 441-448.
    • (2001) Biochem Cell Biol , vol.79 , pp. 441-448
    • Bouganim, N.1    David, J.2    Wysocki, R.3    Ramotar, D.4
  • 24
    • 0030599134 scopus 로고    scopus 로고
    • Cadmium is an inducer of oxidative stress in yeast
    • Brennan RJ & Schiestl RH. (1996) Cadmium is an inducer of oxidative stress in yeast. Mutat Res 356: 171-178.
    • (1996) Mutat Res , vol.356 , pp. 171-178
    • Brennan, R.J.1    Schiestl, R.H.2
  • 25
    • 0017758198 scopus 로고
    • Sulfate uptake in Saccharomyces cerevisiae: biochemical and genetic study
    • Breton A & Surdin-Kerjan Y. (1977) Sulfate uptake in Saccharomyces cerevisiae: biochemical and genetic study. J Bacteriol 132: 224-232.
    • (1977) J Bacteriol , vol.132 , pp. 224-232
    • Breton, A.1    Surdin-Kerjan, Y.2
  • 26
    • 0026770670 scopus 로고
    • Putative GTPbinding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae
    • Bun-Ya M, Harashima S & Oshima Y. (1992) Putative GTPbinding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae. Mol Cell Biol 12: 2958-2966.
    • (1992) Mol Cell Biol , vol.12 , pp. 2958-2966
    • Bun-Ya, M.1    Harashima, S.2    Oshima, Y.3
  • 27
    • 0029913162 scopus 로고    scopus 로고
    • Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae
    • Bun-ya M, Shikata K, Nakade S, Yompakdee C, Harashima S & Oshima Y. (1996) Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae. Curr Genet 29: 344-351.
    • (1996) Curr Genet , vol.29 , pp. 344-351
    • Bun-ya, M.1    Shikata, K.2    Nakade, S.3    Yompakdee, C.4    Harashima, S.5    Oshima, Y.6
  • 28
    • 70349471282 scopus 로고    scopus 로고
    • Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice
    • Carbrey JM, Song L, Zhou Yet al (2009) Reduced arsenic clearance and increased toxicity in aquaglyceroporin-9-null mice. P Natl Acad Sci USA 106: 15956-15960.
    • (2009) P Natl Acad Sci USA , vol.106 , pp. 15956-15960
    • Carbrey, J.M.1    Song, L.2    Zhou Yet, al.3
  • 29
    • 0035138443 scopus 로고    scopus 로고
    • Role of thioredoxin reductase in the Yap1pdependent response to oxidative stress in Saccharomyces cerevisiae
    • Carmel-Harel O, Stearman R, Gasch AP, Botstein D, Brown PO & Storz G. (2001) Role of thioredoxin reductase in the Yap1pdependent response to oxidative stress in Saccharomyces cerevisiae. Mol Microbiol 39: 595-605.
    • (2001) Mol Microbiol , vol.39 , pp. 595-605
    • Carmel-Harel, O.1    Stearman, R.2    Gasch, A.P.3    Botstein, D.4    Brown, P.O.5    Storz, G.6
  • 30
    • 0034672595 scopus 로고    scopus 로고
    • Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
    • Chan JY & Kwong M. (2000) Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. Biochim Biophys Acta 1517: 19-26.
    • (2000) Biochim Biophys Acta , vol.1517 , pp. 19-26
    • Chan, J.Y.1    Kwong, M.2
  • 31
    • 33751544234 scopus 로고    scopus 로고
    • Destabilization of binding to cofactors and SCFMet30 is the rate-limiting regulatory step in degradation of polyubiquitinated Met4
    • Chandrasekaran S, Deffenbaugh AE, Ford DA, Bailly E, Mathias N & Skowyra D. (2006) Destabilization of binding to cofactors and SCFMet30 is the rate-limiting regulatory step in degradation of polyubiquitinated Met4. Mol Cell 24: 689-699.
    • (2006) Mol Cell , vol.24 , pp. 689-699
    • Chandrasekaran, S.1    Deffenbaugh, A.E.2    Ford, D.A.3    Bailly, E.4    Mathias, N.5    Skowyra, D.6
  • 32
    • 12244267727 scopus 로고    scopus 로고
    • Global transcriptional responses of fission yeast to environmental stress
    • Chen D, Toone WM, Mata J et al (2003) Global transcriptional responses of fission yeast to environmental stress. Mol Biol Cell 14: 214-229.
    • (2003) Mol Biol Cell , vol.14 , pp. 214-229
    • Chen, D.1    Toone, W.M.2    Mata, J.3
  • 33
    • 0036118720 scopus 로고    scopus 로고
    • Intracellular signal transduction of cells in response to carcinogenic metals
    • Chen F & Shi X. (2002) Intracellular signal transduction of cells in response to carcinogenic metals. Crit Rev Oncol Hemat 42: 105-121.
    • (2002) Crit Rev Oncol Hemat , vol.42 , pp. 105-121
    • Chen, F.1    Shi, X.2
  • 35
    • 0031018636 scopus 로고    scopus 로고
    • Molecular characterization of two high affinity sulfate transporters in Saccharomyces cerevisiae
    • Cherest H, Davidian JC, Thomas D, Benes V, Ansorge W & Surdin-Kerjan Y. (1997) Molecular characterization of two high affinity sulfate transporters in Saccharomyces cerevisiae. Genetics 145: 627-635.
    • (1997) Genetics , vol.145 , pp. 627-635
    • Cherest, H.1    Davidian, J.C.2    Thomas, D.3    Benes, V.4    Ansorge, W.5    Surdin-Kerjan, Y.6
  • 36
    • 0034714319 scopus 로고    scopus 로고
    • Acute cadmium exposure inactivates thioltransferase (glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis
    • Chrestensen CA, Starke DW & Mieyal JJ. (2000) Acute cadmium exposure inactivates thioltransferase (glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis. J Biol Chem 275: 26556-26565.
    • (2000) J Biol Chem , vol.275 , pp. 26556-26565
    • Chrestensen, C.A.1    Starke, D.W.2    Mieyal, J.J.3
  • 37
    • 33751011307 scopus 로고    scopus 로고
    • Toxic metal accumulation, responses to exposure and mechanisms of tolerance in plants
    • Clemens S. (2006) Toxic metal accumulation, responses to exposure and mechanisms of tolerance in plants. Biochimie 88: 1707-1719.
    • (2006) Biochimie , vol.88 , pp. 1707-1719
    • Clemens, S.1
  • 39
    • 0033564244 scopus 로고    scopus 로고
    • Tolerance to toxic metals by a gene family of phytochelatin synthases from plants and yeast
    • Clemens S, Kim EJ, Neumann D & Schroeder JI. (1999) Tolerance to toxic metals by a gene family of phytochelatin synthases from plants and yeast. EMBO J 18: 3325-3333.
    • (1999) EMBO J , vol.18 , pp. 3325-3333
    • Clemens, S.1    Kim, E.J.2    Neumann, D.3    Schroeder, J.I.4
  • 40
    • 0034819328 scopus 로고    scopus 로고
    • Caenorhabditis elegans expresses a functional phytochelatin synthase
    • Clemens S, Schroeder JI & Degenkolb T. (2001) Caenorhabditis elegans expresses a functional phytochelatin synthase. Eur J Biochem 268: 3640-3643.
    • (2001) Eur J Biochem , vol.268 , pp. 3640-3643
    • Clemens, S.1    Schroeder, J.I.2    Degenkolb, T.3
  • 41
    • 33745737918 scopus 로고    scopus 로고
    • 2 arrest essential for cell survival at high osmolarity
    • 2 arrest essential for cell survival at high osmolarity. EMBO J 25: 2338-2346.
    • (2006) EMBO J , vol.25 , pp. 2338-2346
    • Clotet, J.1    Escote, X.2    Adrover, M.A.3
  • 42
    • 0026707878 scopus 로고
    • COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae
    • Conklin DS, McMaster JA, Culbertson MR & Kung C. (1992) COT1, a gene involved in cobalt accumulation in Saccharomyces cerevisiae. Mol Cell Biol 12: 3678-3688.
    • (1992) Mol Cell Biol , vol.12 , pp. 3678-3688
    • Conklin, D.S.1    McMaster, J.A.2    Culbertson, M.R.3    Kung, C.4
  • 43
    • 0028095510 scopus 로고
    • Interactions between gene products involved in divalent cation transport in Saccharomyces cerevisiae
    • Conklin DS, Culbertson MR & Kung C. (1994) Interactions between gene products involved in divalent cation transport in Saccharomyces cerevisiae. Mol Gen Genet 244: 303-311.
    • (1994) Mol Gen Genet , vol.244 , pp. 303-311
    • Conklin, D.S.1    Culbertson, M.R.2    Kung, C.3
  • 44
    • 15844430252 scopus 로고    scopus 로고
    • The multidrug resistance-associated protein (MRP) subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions
    • Cui Z, Hirata D, Tsuchiya E, Osada H & Miyakawa T. (1996) The multidrug resistance-associated protein (MRP) subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions. J Biol Chem 271: 14712-14716.
    • (1996) J Biol Chem , vol.271 , pp. 14712-14716
    • Cui, Z.1    Hirata, D.2    Tsuchiya, E.3    Osada, H.4    Miyakawa, T.5
  • 45
    • 0027946045 scopus 로고
    • CRS5 encodes a metallothionein-like protein in Saccharomyces cerevisiae
    • Culotta VC, Howard WR & Liu XF. (1994) CRS5 encodes a metallothionein-like protein in Saccharomyces cerevisiae. J Biol Chem 269: 25295-25302.
    • (1994) J Biol Chem , vol.269 , pp. 25295-25302
    • Culotta, V.C.1    Howard, W.R.2    Liu, X.F.3
  • 46
    • 0024341981 scopus 로고
    • Glutathione-coated cadmium-sulfide crystallites in Candida glabrata
    • Dameron CT, Smith BR &Winge DR. (1989) Glutathione-coated cadmium-sulfide crystallites in Candida glabrata. J Biol Chem 264: 17355-17360.
    • (1989) J Biol Chem , vol.264 , pp. 17355-17360
    • Dameron, C.T.1    Smith, B.R.2    Winge, D.R.3
  • 47
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
    • D'Autreaux B & Toledano MB. (2007) ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Bio 8: 813-824.
    • (2007) Nat Rev Mol Cell Bio , vol.8 , pp. 813-824
    • D'Autreaux, B.1    Toledano, M.B.2
  • 49
    • 0034597012 scopus 로고    scopus 로고
    • 2 sensing through oxidation of the Yap1 transcription factor
    • 2 sensing through oxidation of the Yap1 transcription factor. EMBO J 19: 5157-5166.
    • (2000) EMBO J , vol.19 , pp. 5157-5166
    • Delaunay, A.1    Isnard, A.D.2    Toledano, M.B.3
  • 51
    • 33846960761 scopus 로고    scopus 로고
    • Regulation of the arsenic-responsive transcription factor Yap8p involves the ubiquitin-proteasome pathway
    • Di Y & Tamás MJ. (2007) Regulation of the arsenic-responsive transcription factor Yap8p involves the ubiquitin-proteasome pathway. J Cell Sci 120: 256-264.
    • (2007) J Cell Sci , vol.120 , pp. 256-264
    • Di, Y.1    Tamás, M.J.2
  • 52
    • 40149097447 scopus 로고    scopus 로고
    • Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid
    • Dilda PJ, Perrone GG, Philp A, Lock RB, Dawes IW & Hogg PJ. (2008) Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid. Int J Biochem Cell B 40: 1016-1029.
    • (2008) Int J Biochem Cell B , vol.40 , pp. 1016-1029
    • Dilda, P.J.1    Perrone, G.G.2    Philp, A.3    Lock, R.B.4    Dawes, I.W.5    Hogg, P.J.6
  • 53
    • 0030923008 scopus 로고    scopus 로고
    • Characterization of the FET4 protein of yeast Evidence for a direct role in the transport of iron
    • Dix D, Bridgham J, Broderius M & Eide D. (1997) Characterization of the FET4 protein of yeast. Evidence for a direct role in the transport of iron. J Biol Chem 272: 11770-11777.
    • (1997) J Biol Chem , vol.272 , pp. 11770-11777
    • Dix, D.1    Bridgham, J.2    Broderius, M.3    Eide, D.4
  • 54
    • 0028053806 scopus 로고
    • The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae
    • Dix DR, Bridgham JT, Broderius MA, Byersdorfer CA & Eide DJ. (1994) The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae. J Biol Chem 269: 26092-26099.
    • (1994) J Biol Chem , vol.269 , pp. 26092-26099
    • Dix, D.R.1    Bridgham, J.T.2    Broderius, M.A.3    Byersdorfer, C.A.4    Eide, D.J.5
  • 55
    • 11244327652 scopus 로고    scopus 로고
    • Nuclear localization destabilizes the stress-regulated transcription factor Msn2
    • Durchschlag E, Reiter W, Ammerer G & Schuller C. (2004) Nuclear localization destabilizes the stress-regulated transcription factor Msn2. J Biol Chem 279: 55425-55432.
    • (2004) J Biol Chem , vol.279 , pp. 55425-55432
    • Durchschlag, E.1    Reiter, W.2    Ammerer, G.3    Schuller, C.4
  • 57
    • 0032502738 scopus 로고    scopus 로고
    • Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells Role of mitogen-activated protein kinases
    • Elbirt KK, Whitmarsh AJ, Davis RJ & Bonkovsky HL. (1998) Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases. J Biol Chem 273: 8922-8931.
    • (1998) J Biol Chem , vol.273 , pp. 8922-8931
    • Elbirt, K.K.1    Whitmarsh, A.J.2    Davis, R.J.3    Bonkovsky, H.L.4
  • 59
    • 0031794474 scopus 로고    scopus 로고
    • Sequence analyses and phylogenetic characterization of the ZIP family of metal ion transport proteins
    • Eng BH, Guerinot ML, Eide D & Saier MH Jr. (1998) Sequence analyses and phylogenetic characterization of the ZIP family of metal ion transport proteins. J Membrane Biol 166: 1-7.
    • (1998) J Membrane Biol , vol.166 , pp. 1-7
    • Eng, B.H.1    Guerinot, M.L.2    Eide, D.3    Saier M.H., Jr.4
  • 60
    • 31944434598 scopus 로고    scopus 로고
    • Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans
    • Enjalbert B, Smith DA, Cornell MJ, Alam I, Nicholls S, Brown AJ & Quinn J. (2006) Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans. Mol Biol Cell 17: 1018-1032.
    • (2006) Mol Biol Cell , vol.17 , pp. 1018-1032
    • Enjalbert, B.1    Smith, D.A.2    Cornell, M.J.3    Alam, I.4    Nicholls, S.5    Brown, A.J.6    Quinn, J.7
  • 61
    • 8844236212 scopus 로고    scopus 로고
    • Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser(908) and Thr(911)
    • Eraso P, Martinez-Burgos M, Falcon-Perez JM, Portillo F & Mazon MJ. (2004) Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser(908) and Thr(911). FEBS Lett 577: 322-326.
    • (2004) FEBS Lett , vol.577 , pp. 322-326
    • Eraso, P.1    Martinez-Burgos, M.2    Falcon-Perez, J.M.3    Portillo, F.4    Mazon, M.J.5
  • 62
    • 0035750172 scopus 로고    scopus 로고
    • Toxic metals and oxidative stress part I: mechanisms involved in metalinduced oxidative damage
    • Ercal N, Gurer-Orhan H & Aykin-Burns N. (2001) Toxic metals and oxidative stress part I: mechanisms involved in metalinduced oxidative damage. Curr Top Med Chem 1: 529-539.
    • (2001) Curr Top Med Chem , vol.1 , pp. 529-539
    • Ercal, N.1    Gurer-Orhan, H.2    Aykin-Burns, N.3
  • 63
    • 5444253797 scopus 로고    scopus 로고
    • Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1
    • Escoté X, Zapater M, Clotet J & Posas F. (2004) Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1. Nat Cell Biol 6: 997-1002.
    • (2004) Nat Cell Biol , vol.6 , pp. 997-1002
    • Escoté, X.1    Zapater, M.2    Clotet, J.3    Posas, F.4
  • 65
    • 18344387669 scopus 로고    scopus 로고
    • Sulfur sparing in the yeast proteome in response to sulfur demand
    • Fauchon M, Lagniel G, Aude JC et al (2002) Sulfur sparing in the yeast proteome in response to sulfur demand. Mol Cell 9: 713-723.
    • (2002) Mol Cell , vol.9 , pp. 713-723
    • Fauchon, M.1    Lagniel, G.2    Aude, J.C.3
  • 66
    • 18144432725 scopus 로고    scopus 로고
    • Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
    • Fauman EB, Cogswell JP, Lovejoy B et al (1998) Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A. Cell 93: 617-625.
    • (1998) Cell , vol.93 , pp. 617-625
    • Fauman, E.B.1    Cogswell, J.P.2    Lovejoy, B.3
  • 67
    • 0030712874 scopus 로고    scopus 로고
    • Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions
    • Fernandes L, Rodrigues-Pousada C & Struhl K. (1997) Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol 17: 6982-6993.
    • (1997) Mol Cell Biol , vol.17 , pp. 6982-6993
    • Fernandes, L.1    Rodrigues-Pousada, C.2    Struhl, K.3
  • 68
    • 33744967943 scopus 로고    scopus 로고
    • A ubiquitininteracting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome
    • Flick K, Raasi S, Zhang H, Yen JL & Kaiser P. (2006) A ubiquitininteracting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome. Nat Cell Biol 8: 509-515.
    • (2006) Nat Cell Biol , vol.8 , pp. 509-515
    • Flick, K.1    Raasi, S.2    Zhang, H.3    Yen, J.L.4    Kaiser, P.5
  • 69
    • 0343299702 scopus 로고
    • Tandem gene amplification mediates copper resistance in yeast
    • Fogel S & Welch JW. (1982) Tandem gene amplification mediates copper resistance in yeast. P Natl Acad Sci USA 79: 5342-5346.
    • (1982) P Natl Acad Sci USA , vol.79 , pp. 5342-5346
    • Fogel, S.1    Welch, J.W.2
  • 70
    • 67749129499 scopus 로고    scopus 로고
    • Properties of arsenite efflux permeases (Acr3) from Alkaliphilus metalliredigens and Corynebacterium glutamicum
    • Fu HL, Meng Y, Ordonez E et al (2009) Properties of arsenite efflux permeases (Acr3) from Alkaliphilus metalliredigens and Corynebacterium glutamicum. J Biol Chem 284: 19887-19895.
    • (2009) J Biol Chem , vol.284 , pp. 19887-19895
    • Fu, H.L.1    Meng, Y.2    Ordonez, E.3
  • 72
    • 0033637153 scopus 로고    scopus 로고
    • Genomic expression programs in the response of yeast cells to environmental changes
    • Gasch AP, Spellman PT, Kao CM et al (2000) Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell 11: 4241-4257.
    • (2000) Mol Biol Cell , vol.11 , pp. 4241-4257
    • Gasch, A.P.1    Spellman, P.T.2    Kao, C.M.3
  • 73
    • 0033609012 scopus 로고    scopus 로고
    • Pathways of As(III) detoxification in Saccharomyces cerevisiae
    • Ghosh M, Shen J & Rosen BP. (1999) Pathways of As(III) detoxification in Saccharomyces cerevisiae. P Natl Acad Sci USA 96: 5001-5006.
    • (1999) P Natl Acad Sci USA , vol.96 , pp. 5001-5006
    • Ghosh, M.1    Shen, J.2    Rosen, B.P.3
  • 74
    • 0034161957 scopus 로고    scopus 로고
    • Zinc-regulated ubiquitin conjugation signals endocytosis of the yeast ZRT1 zinc transporter
    • Gitan RS & Eide DJ. (2000) Zinc-regulated ubiquitin conjugation signals endocytosis of the yeast ZRT1 zinc transporter. Biochem J 346: 329-336.
    • (2000) Biochem J , vol.346 , pp. 329-336
    • Gitan, R.S.1    Eide, D.J.2
  • 75
    • 0032582814 scopus 로고    scopus 로고
    • Zincinduced inactivation of the yeast ZRT1 zinc transporter occurs through endocytosis and vacuolar degradation
    • Gitan RS, Luo H, Rodgers J, Broderius M & Eide D. (1998) Zincinduced inactivation of the yeast ZRT1 zinc transporter occurs through endocytosis and vacuolar degradation. J Biol Chem 273: 28617-28624.
    • (1998) J Biol Chem , vol.273 , pp. 28617-28624
    • Gitan, R.S.1    Luo, H.2    Rodgers, J.3    Broderius, M.4    Eide, D.5
  • 76
    • 0141994845 scopus 로고    scopus 로고
    • A cytosolic domain of the yeast Zrt1 zinc transporter is required for its post-translational inactivation in response to zinc and cadmium
    • Gitan RS, Shababi M, Kramer M & Eide DJ. (2003) A cytosolic domain of the yeast Zrt1 zinc transporter is required for its post-translational inactivation in response to zinc and cadmium. J Biol Chem 278: 39558-39564.
    • (2003) J Biol Chem , vol.278 , pp. 39558-39564
    • Gitan, R.S.1    Shababi, M.2    Kramer, M.3    Eide, D.J.4
  • 77
    • 61349147706 scopus 로고    scopus 로고
    • Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
    • Gitler AD, Chesi A, Geddie ML et al (2009) Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat Genet 41: 308-315.
    • (2009) Nat Genet , vol.41 , pp. 308-315
    • Gitler, A.D.1    Chesi, A.2    Geddie, M.L.3
  • 78
    • 0346727127 scopus 로고    scopus 로고
    • Protein degradation and protection against misfolded or damaged proteins
    • Goldberg AL. (2003) Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-899.
    • (2003) Nature , vol.426 , pp. 895-899
    • Goldberg, A.L.1
  • 80
    • 0032518996 scopus 로고    scopus 로고
    • 2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity
    • 2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Gene Dev 12: 586-597.
    • (1998) Gene Dev , vol.12 , pp. 586-597
    • Görner, W.1    Durchschlag, E.2    Martinez-Pastor, M.T.3
  • 81
    • 3843084085 scopus 로고    scopus 로고
    • Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin
    • Gourbal B, Sonuc N, Bhattacharjee H et al (2004) Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin. J Biol Chem 279: 31010-31017.
    • (2004) J Biol Chem , vol.279 , pp. 31010-31017
    • Gourbal, B.1    Sonuc, N.2    Bhattacharjee, H.3
  • 82
    • 0035131144 scopus 로고    scopus 로고
    • Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions
    • Grant CM. (2001) Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions. Mol Microbiol 39: 533-541.
    • (2001) Mol Microbiol , vol.39 , pp. 533-541
    • Grant, C.M.1
  • 84
    • 0034644739 scopus 로고    scopus 로고
    • Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays
    • Gross C, Kelleher M, Iyer VR, Brown PO &Winge DR. (2000) Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays. J Biol Chem 275: 32310-32316.
    • (2000) J Biol Chem , vol.275 , pp. 32310-32316
    • Gross, C.1    Kelleher, M.2    Iyer, V.R.3    Brown, P.O.4    Winge, D.R.5
  • 86
    • 16544384294 scopus 로고    scopus 로고
    • YBP1 and its homologue YBP2/YBH1 influence oxidative-stress tolerance by nonidentical mechanisms in Saccharomyces cerevisiae
    • Gulshan K, Rovinsky SA &Moye-Rowley WS. (2004) YBP1 and its homologue YBP2/YBH1 influence oxidative-stress tolerance by nonidentical mechanisms in Saccharomyces cerevisiae. Eukaryot Cell 3: 318-330.
    • (2004) Eukaryot Cell , vol.3 , pp. 318-330
    • Gulshan, K.1    Rovinsky, S.A.2    Moye-Rowley, W.S.3
  • 87
    • 0033149934 scopus 로고    scopus 로고
    • Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe
    • Ha SB, Smith AP, Howden R et al (1999) Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe. Plant Cell 11: 1153-1164.
    • (1999) Plant Cell , vol.11 , pp. 1153-1164
    • Ha, S.B.1    Smith, A.P.2    Howden, R.3
  • 88
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals, transition metals and disease
    • Halliwell B & Gutteridge JM. (1984) Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 219: 1-14.
    • (1984) Biochem J , vol.219 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.2
  • 89
    • 34249864120 scopus 로고    scopus 로고
    • A proteasome for all occasions
    • Hanna J & Finley D. (2007) A proteasome for all occasions. FEBS Lett 581: 2854-2861.
    • (2007) FEBS Lett , vol.581 , pp. 2854-2861
    • Hanna, J.1    Finley, D.2
  • 90
    • 0033794872 scopus 로고    scopus 로고
    • Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae
    • Hansen J & Johannsen PF. (2000) Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet 263: 535-542.
    • (2000) Mol Gen Genet , vol.263 , pp. 535-542
    • Hansen, J.1    Johannsen, P.F.2
  • 91
    • 4544352942 scopus 로고    scopus 로고
    • Transcriptional regulatory code of a eukaryotic genome
    • Harbison CT, Gordon DB, Lee TI et al (2004) Transcriptional regulatory code of a eukaryotic genome. Nature 431: 99-104.
    • (2004) Nature , vol.431 , pp. 99-104
    • Harbison, C.T.1    Gordon, D.B.2    Lee, T.I.3
  • 92
    • 0344845144 scopus 로고    scopus 로고
    • Signaling by carcinogenic metals and metal-induced reactive oxygen species
    • Harris GK & Shi X. (2003) Signaling by carcinogenic metals and metal-induced reactive oxygen species. Mutat Res 533: 183-200.
    • (2003) Mutat Res , vol.533 , pp. 183-200
    • Harris, G.K.1    Shi, X.2
  • 93
    • 14844303289 scopus 로고    scopus 로고
    • SCF(Pof1)-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast
    • Harrison C, Katayama S, Dhut S, Chen D, Jones N, Bahler J & Toda T. (2005) SCF(Pof1)-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast. EMBO J 24: 599-610.
    • (2005) EMBO J , vol.24 , pp. 599-610
    • Harrison, C.1    Katayama, S.2    Dhut, S.3    Chen, D.4    Jones, N.5    Bahler, J.6    Toda, T.7
  • 94
    • 0034871083 scopus 로고    scopus 로고
    • Zinc finger proteins as potential targets for toxic metal ions: differential effects on structure and function
    • Hartwig A. (2001) Zinc finger proteins as potential targets for toxic metal ions: differential effects on structure and function. Antioxid Redox Sign 3: 625-634.
    • (2001) Antioxid Redox Sign , vol.3 , pp. 625-634
    • Hartwig, A.1
  • 95
    • 0034667662 scopus 로고    scopus 로고
    • The Fe(II) permease Fet4p functions as a low affinity copper transporter and supports normal copper trafficking in Saccharomyces cerevisiae
    • Hassett R, Dix DR, Eide DJ & Kosman DJ. (2000) The Fe(II) permease Fet4p functions as a low affinity copper transporter and supports normal copper trafficking in Saccharomyces cerevisiae. Biochem J 351: 477-484.
    • (2000) Biochem J , vol.351 , pp. 477-484
    • Hassett, R.1    Dix, D.R.2    Eide, D.J.3    Kosman, D.J.4
  • 96
    • 18944372150 scopus 로고    scopus 로고
    • Integrating phenotypic and expression profiles to map arsenic-response networks
    • Haugen AC, Kelley R, Collins JB et al (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol 5: R95.
    • (2004) Genome Biol , vol.5
    • Haugen, A.C.1    Kelley, R.2    Collins, J.B.3
  • 97
    • 28244500972 scopus 로고    scopus 로고
    • Identification of novel Yap1p and Skn7p binding sites involved in the oxidative stress response of Saccharomyces cerevisiae
    • He XJ & Fassler JS. (2005) Identification of novel Yap1p and Skn7p binding sites involved in the oxidative stress response of Saccharomyces cerevisiae. Mol Microbiol 58: 1454-1467.
    • (2005) Mol Microbiol , vol.58 , pp. 1454-1467
    • He, X.J.1    Fassler, J.S.2
  • 98
    • 0028084437 scopus 로고
    • Stress-induced transcriptional activation mediated by YAP1 and YAP2 genes that encode the Jun family of transcriptional activators in Saccharomyces cerevisiae
    • Hirata D, Yano K & Miyakawa T. (1994) Stress-induced transcriptional activation mediated by YAP1 and YAP2 genes that encode the Jun family of transcriptional activators in Saccharomyces cerevisiae. Mol Gen Genet 242: 250-256.
    • (1994) Mol Gen Genet , vol.242 , pp. 250-256
    • Hirata, D.1    Yano, K.2    Miyakawa, T.3
  • 99
    • 0026623536 scopus 로고
    • Iodophenylarsine oxide and arsenical affinity chromatography: new probes for dithiol proteins Application to tubulins and to components of the insulin receptor-glucose transporter signal transduction pathway
    • Hoffman RD & Lane MD. (1992) Iodophenylarsine oxide and arsenical affinity chromatography: new probes for dithiol proteins. Application to tubulins and to components of the insulin receptor-glucose transporter signal transduction pathway. J Biol Chem 267: 14005-14011.
    • (1992) J Biol Chem , vol.267 , pp. 14005-14011
    • Hoffman, R.D.1    Lane, M.D.2
  • 100
    • 40449105407 scopus 로고    scopus 로고
    • Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity
    • Holland S, Lodwig E, Sideri T et al (2007) Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity. Genome Biol 8: R268.
    • (2007) Genome Biol , vol.8
    • Holland, S.1    Lodwig, E.2    Sideri, T.3
  • 101
    • 70349294042 scopus 로고    scopus 로고
    • Actin-mediated endocytosis limits intracellular Cr accumulation and Cr toxicity during chromate stress
    • Holland SL & Avery SV. (2009) Actin-mediated endocytosis limits intracellular Cr accumulation and Cr toxicity during chromate stress. Toxicol Sci 111: 437-446.
    • (2009) Toxicol Sci , vol.111 , pp. 437-446
    • Holland, S.L.1    Avery, S.V.2
  • 102
    • 64049095839 scopus 로고    scopus 로고
    • Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response
    • Hosiner D, Lempiainen H, Reiter W et al (2009) Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response. Mol Biol Cell 20: 1048-1057.
    • (2009) Mol Biol Cell , vol.20 , pp. 1048-1057
    • Hosiner, D.1    Lempiainen, H.2    Reiter, W.3
  • 103
    • 0030748392 scopus 로고    scopus 로고
    • Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation
    • Howlett NG & Avery SV. (1997) Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. Appl Environ Microb 63: 2971-2976.
    • (1997) Appl Environ Microb , vol.63 , pp. 2971-2976
    • Howlett, N.G.1    Avery, S.V.2
  • 104
    • 15744375795 scopus 로고    scopus 로고
    • Overexpression of Bop3 confers resistance to methylmercury in Saccharomyces cerevisiae through interaction with other proteins such as Fkh1, Rts1, and Msn2
    • Hwang GW, Furuoya Y, Hiroshima A, Furuchi T & Naganuma A. (2005) Overexpression of Bop3 confers resistance to methylmercury in Saccharomyces cerevisiae through interaction with other proteins such as Fkh1, Rts1, and Msn2. Biochem Bioph Res Co 330: 378-385.
    • (2005) Biochem Bioph Res Co , vol.330 , pp. 378-385
    • Hwang, G.W.1    Furuoya, Y.2    Hiroshima, A.3    Furuchi, T.4    Naganuma, A.5
  • 106
    • 42749092894 scopus 로고    scopus 로고
    • The Arabidopsis thaliana aquaglyceroporin AtNIP7;1 is a pathway for arsenite uptake
    • Isayenkov SV & Maathuis FJ. (2008) The Arabidopsis thaliana aquaglyceroporin AtNIP7;1 is a pathway for arsenite uptake. FEBS Lett 582: 1625-1628.
    • (2008) FEBS Lett , vol.582 , pp. 1625-1628
    • Isayenkov, S.V.1    Maathuis, F.J.2
  • 107
    • 0033214613 scopus 로고    scopus 로고
    • Thioredoxin deficiency causes the constitutive activation of Yap1, an AP-1-like transcription factor in Saccharomyces cerevisiae
    • Izawa S, Maeda K, Sugiyama K, Mano J, Inoue Y & Kimura A. (1999) Thioredoxin deficiency causes the constitutive activation of Yap1, an AP-1-like transcription factor in Saccharomyces cerevisiae. J Biol Chem 274: 28459-28465.
    • (1999) J Biol Chem , vol.274 , pp. 28459-28465
    • Izawa, S.1    Maeda, K.2    Sugiyama, K.3    Mano, J.4    Inoue, Y.5    Kimura, A.6
  • 108
    • 0036302227 scopus 로고    scopus 로고
    • Regulation of Saccharomyces cerevisiae FET4 by oxygen and iron
    • Jensen LT & Culotta VC. (2002) Regulation of Saccharomyces cerevisiae FET4 by oxygen and iron. J Mol Biol 318: 251-260.
    • (2002) J Mol Biol , vol.318 , pp. 251-260
    • Jensen, L.T.1    Culotta, V.C.2
  • 109
    • 0029767918 scopus 로고    scopus 로고
    • Enhanced effectiveness of copper ion buffering by CUP1 metallothionein compared with CRS5 metallothionein in Saccharomyces cerevisiae
    • Jensen LT, Howard WR, Strain JJ,Winge DR & Culotta VC. (1996) Enhanced effectiveness of copper ion buffering by CUP1 metallothionein compared with CRS5 metallothionein in Saccharomyces cerevisiae. J Biol Chem 271: 18514-18519.
    • (1996) J Biol Chem , vol.271 , pp. 18514-18519
    • Jensen, L.T.1    Howard, W.R.2    Strain, J.J.3    Winge, D.R.4    Culotta, V.C.5
  • 110
    • 0142180122 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae high affinity phosphate transporter encoded by PHO84 also functions in manganese homeostasis
    • Jensen LT, Ajua-Alemanji M & Culotta VC. (2003) The Saccharomyces cerevisiae high affinity phosphate transporter encoded by PHO84 also functions in manganese homeostasis. J Biol Chem 278: 42036-42040.
    • (2003) J Biol Chem , vol.278 , pp. 42036-42040
    • Jensen, L.T.1    Ajua-Alemanji, M.2    Culotta, V.C.3
  • 111
    • 0037716637 scopus 로고    scopus 로고
    • Cadmium is a mutagen that acts by inhibiting mismatch repair
    • Jin YH, Clark AB, Slebos RJ et al (2003) Cadmium is a mutagen that acts by inhibiting mismatch repair. Nat Genet 34: 326-329.
    • (2003) Nat Genet , vol.34 , pp. 326-329
    • Jin, Y.H.1    Clark, A.B.2    Slebos, R.J.3
  • 113
    • 36949008164 scopus 로고    scopus 로고
    • Identification of genes involved in the toxic response of Saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants
    • Jo WJ, Loguinov A, Chang M et al (2008) Identification of genes involved in the toxic response of Saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants. Toxicol Sci 101: 140-151.
    • (2008) Toxicol Sci , vol.101 , pp. 140-151
    • Jo, W.J.1    Loguinov, A.2    Chang, M.3
  • 114
    • 70349281883 scopus 로고    scopus 로고
    • Comparative functional genomic analysis identifies distinct and overlapping sets of genes required for resistance to monomethylarsonous acid (MMAIII) and arsenite (AsIII) in yeast
    • Jo WJ, Loguinov A,Wintz H et al (2009) Comparative functional genomic analysis identifies distinct and overlapping sets of genes required for resistance to monomethylarsonous acid (MMAIII) and arsenite (AsIII) in yeast. Toxicol Sci 111: 424-436.
    • (2009) Toxicol Sci , vol.111 , pp. 424-436
    • Jo, W.J.1    Loguinov, A.2    Wintz, H.3
  • 115
  • 116
    • 0024741152 scopus 로고
    • Identification of a gene conferring resistance to zinc and cadmium ions in the yeast Saccharomyces cerevisiae
    • Kamizono A, Nishizawa M, Teranishi Y, Murata K & Kimura A. (1989) Identification of a gene conferring resistance to zinc and cadmium ions in the yeast Saccharomyces cerevisiae. Mol Gen Genet 219: 161-167.
    • (1989) Mol Gen Genet , vol.219 , pp. 161-167
    • Kamizono, A.1    Nishizawa, M.2    Teranishi, Y.3    Murata, K.4    Kimura, A.5
  • 117
    • 0028807740 scopus 로고
    • Expression of an ATPbinding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae
    • Katzmann DJ, Hallstrom TC, Voet M, Wysock W, Golin J, Volckaert G &Moye-Rowley WS. (1995) Expression of an ATPbinding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae. Mol Cell Biol 15: 6875-6883.
    • (1995) Mol Cell Biol , vol.15 , pp. 6875-6883
    • Katzmann, D.J.1    Hallstrom, T.C.2    Voet, M.3    Wysock, W.4    Golin, J.5    Volckaert, G.6    Moye-Rowley, W.S.7
  • 119
    • 17744370521 scopus 로고    scopus 로고
    • The function of Alr1p of Saccharomyces cerevisiae in cadmium detoxification: insights from phylogenetic studies and particle-induced X-ray emission
    • Kern AL, Bonatto D, Dias JF, Yoneama ML, Brendel M & Pegas Henriques JA. (2005) The function of Alr1p of Saccharomyces cerevisiae in cadmium detoxification: insights from phylogenetic studies and particle-induced X-ray emission. Biometals 18: 31-41.
    • (2005) Biometals , vol.18 , pp. 31-41
    • Kern, A.L.1    Bonatto, D.2    Dias, J.F.3    Yoneama, M.L.4    Brendel, M.5    Pegas Henriques, J.A.6
  • 120
    • 39549101455 scopus 로고    scopus 로고
    • The role of protein binding of trivalent arsenicals in arsenic carcinogenesis and toxicity
    • Kitchin KT & Wallace K. (2008) The role of protein binding of trivalent arsenicals in arsenic carcinogenesis and toxicity. J Inorg Biochem 102: 532-539.
    • (2008) J Inorg Biochem , vol.102 , pp. 532-539
    • Kitchin, K.T.1    Wallace, K.2
  • 121
    • 0026578156 scopus 로고
    • Saccharomyces cerevisiae and Neurospora crassa contain heavy metal sequestering phytochelatin
    • Kneer R, Kutchan TM, Hochberger A & Zenk MH. (1992) Saccharomyces cerevisiae and Neurospora crassa contain heavy metal sequestering phytochelatin. Arch Microbiol 157: 305-310.
    • (1992) Arch Microbiol , vol.157 , pp. 305-310
    • Kneer, R.1    Kutchan, T.M.2    Hochberger, A.3    Zenk, M.H.4
  • 122
    • 3543008924 scopus 로고    scopus 로고
    • Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
    • Kobayashi A, Kang MI, Okawa H et al (2004) Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 24: 7130-7139.
    • (2004) Mol Cell Biol , vol.24 , pp. 7130-7139
    • Kobayashi, A.1    Kang, M.I.2    Okawa, H.3
  • 123
    • 66249129718 scopus 로고    scopus 로고
    • Evolutionary forces act on promoter length: identification of enriched cis-regulatory elements
    • Kristiansson E, Thorsen M, Tamás MJ & Nerman O. (2009) Evolutionary forces act on promoter length: identification of enriched cis-regulatory elements. Mol Biol Evol 26: 1299-1307.
    • (2009) Mol Biol Evol , vol.26 , pp. 1299-1307
    • Kristiansson, E.1    Thorsen, M.2    Tamás, M.J.3    Nerman, O.4
  • 124
    • 0028057226 scopus 로고
    • YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides
    • Kuge S & Jones N. (1994) YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J 13: 655-664.
    • (1994) EMBO J , vol.13 , pp. 655-664
    • Kuge, S.1    Jones, N.2
  • 125
    • 0030942294 scopus 로고    scopus 로고
    • Regulation of yAP-1 nuclear localization in response to oxidative stress
    • Kuge S, Jones N & Nomoto A. (1997) Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J 16: 1710-1720.
    • (1997) EMBO J , vol.16 , pp. 1710-1720
    • Kuge, S.1    Jones, N.2    Nomoto, A.3
  • 126
    • 0031595764 scopus 로고    scopus 로고
    • Crm1 (XpoI) dependent nuclear export of the budding yeast transcription factor yAP-1 is sensitive to oxidative stress
    • Kuge S, Toda T, Iizuka N & Nomoto A. (1998) Crm1 (XpoI) dependent nuclear export of the budding yeast transcription factor yAP-1 is sensitive to oxidative stress. Genes Cells 3: 521-532.
    • (1998) Genes Cells , vol.3 , pp. 521-532
    • Kuge, S.1    Toda, T.2    Iizuka, N.3    Nomoto, A.4
  • 127
    • 0035726624 scopus 로고    scopus 로고
    • Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation
    • Kuge S, Arita M, Murayama A, Maeta K, Izawa S, Inoue Y & Nomoto A. (2001) Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation. Mol Cell Biol 21: 6139-6150.
    • (2001) Mol Cell Biol , vol.21 , pp. 6139-6150
    • Kuge, S.1    Arita, M.2    Murayama, A.3    Maeta, K.4    Izawa, S.5    Inoue, Y.6    Nomoto, A.7
  • 128
    • 3242701547 scopus 로고    scopus 로고
    • Biology, structure and mechanism of Ptype ATPases
    • Kühlbrandt W. (2004) Biology, structure and mechanism of Ptype ATPases. Nat Rev Mol Cell Bio 5: 282-295.
    • (2004) Nat Rev Mol Cell Bio , vol.5 , pp. 282-295
    • Kühlbrandt, W.1
  • 129
    • 0030925073 scopus 로고    scopus 로고
    • Assembly of a bZIP-bHLH transcription activation complex: formation of the yeast Cbf1-Met4-Met28 complex is regulated through Met28 stimulation of Cbf1 DNA binding
    • Kuras L, Barbey R & Thomas D. (1997) Assembly of a bZIP-bHLH transcription activation complex: formation of the yeast Cbf1-Met4-Met28 complex is regulated through Met28 stimulation of Cbf1 DNA binding. EMBO J 16: 2441-2451.
    • (1997) EMBO J , vol.16 , pp. 2441-2451
    • Kuras, L.1    Barbey, R.2    Thomas, D.3
  • 130
    • 0036348150 scopus 로고    scopus 로고
    • Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment
    • Kuras L, Rouillon A, Lee T, Barbey R, Tyers M & Thomas D. (2002) Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment. Mol Cell 10: 69-80.
    • (2002) Mol Cell , vol.10 , pp. 69-80
    • Kuras, L.1    Rouillon, A.2    Lee, T.3    Barbey, R.4    Tyers, M.5    Thomas, D.6
  • 131
    • 21644458327 scopus 로고    scopus 로고
    • Combined proteome and metaboliteprofiling analyses reveal surprising insights into yeast sulfur metabolism
    • Lafaye A, Junot C, Pereira Y, Lagniel G, Tabet JC, Ezan E & Labarre J. (2005) Combined proteome and metaboliteprofiling analyses reveal surprising insights into yeast sulfur metabolism. J Biol Chem 280: 24723-24730.
    • (2005) J Biol Chem , vol.280 , pp. 24723-24730
    • Lafaye, A.1    Junot, C.2    Pereira, Y.3    Lagniel, G.4    Tabet, J.C.5    Ezan, E.6    Labarre, J.7
  • 132
    • 0033967340 scopus 로고    scopus 로고
    • Pho86p, an endoplasmic reticulum (ER) resident protein in Saccharomyces cerevisiae, is required for ER exit of the high-affinity phosphate transporter Pho84p
    • Lau WT, Howson RW, Malkus P, Schekman R & O'Shea EK. (2000) Pho86p, an endoplasmic reticulum (ER) resident protein in Saccharomyces cerevisiae, is required for ER exit of the high-affinity phosphate transporter Pho84p. P Natl Acad Sci USA 97: 1107-1112.
    • (2000) P Natl Acad Sci USA , vol.97 , pp. 1107-1112
    • Lau, W.T.1    Howson, R.W.2    Malkus, P.3    Schekman, R.4    O'Shea, E.K.5
  • 135
    • 67349113489 scopus 로고    scopus 로고
    • Ubiquitin ligase adaptors: regulators of ubiquitylation and endocytosis of plasma membrane proteins
    • Leon S & Haguenauer-Tsapis R. (2009) Ubiquitin ligase adaptors: regulators of ubiquitylation and endocytosis of plasma membrane proteins. Exp Cell Res 315: 1574-1583.
    • (2009) Exp Cell Res , vol.315 , pp. 1574-1583
    • Leon, S.1    Haguenauer-Tsapis, R.2
  • 136
    • 0031013876 scopus 로고    scopus 로고
    • A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium
    • Li ZS, Lu YP, Zhen RG, Szczypka M, Thiele DJ & Rea PA. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. P Natl Acad Sci USA 94: 42-47.
    • (1997) P Natl Acad Sci USA , vol.94 , pp. 42-47
    • Li, Z.S.1    Lu, Y.P.2    Zhen, R.G.3    Szczypka, M.4    Thiele, D.J.5    Rea, P.A.6
  • 137
    • 62649089109 scopus 로고    scopus 로고
    • Population genomics of domestic and wild yeasts
    • Liti G, Carter DM, Moses AM et al (2009) Population genomics of domestic and wild yeasts. Nature 458: 337-341.
    • (2009) Nature , vol.458 , pp. 337-341
    • Liti, G.1    Carter, D.M.2    Moses, A.M.3
  • 138
    • 0035852735 scopus 로고    scopus 로고
    • Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity
    • Liu SX, Athar M, Lippai I,Waldren C & Hei TK. (2001) Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity. P Natl Acad Sci USA 98: 1643-1648.
    • (2001) P Natl Acad Sci USA , vol.98 , pp. 1643-1648
    • Liu, S.X.1    Athar, M.2    Lippai, I.3    Waldren, C.4    Hei, T.K.5
  • 139
    • 0001352978 scopus 로고    scopus 로고
    • Post-translation control of Nramp metal transport in yeast Role of metal ions and the BSD2 gene
    • Liu XF & Culotta VC. (1999) Post-translation control of Nramp metal transport in yeast. Role of metal ions and the BSD2 gene. J Biol Chem 274: 4863-4868.
    • (1999) J Biol Chem , vol.274 , pp. 4863-4868
    • Liu, X.F.1    Culotta, V.C.2
  • 140
    • 0001726322 scopus 로고    scopus 로고
    • Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene
    • Liu XF, Supek F, Nelson N & Culotta VC. (1997) Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene. J Biol Chem 272: 11763-11769.
    • (1997) J Biol Chem , vol.272 , pp. 11763-11769
    • Liu, X.F.1    Supek, F.2    Nelson, N.3    Culotta, V.C.4
  • 142
    • 2342434545 scopus 로고    scopus 로고
    • Arsenic trioxide uptake by hexose permeases in Saccharomyces cerevisiae
    • Liu Z, Boles E & Rosen BP. (2004) Arsenic trioxide uptake by hexose permeases in Saccharomyces cerevisiae. J Biol Chem 279: 17312-17318.
    • (2004) J Biol Chem , vol.279 , pp. 17312-17318
    • Liu, Z.1    Boles, E.2    Rosen, B.P.3
  • 143
    • 34547644483 scopus 로고    scopus 로고
    • Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
    • Lu J, Chew EH & Holmgren A. (2007) Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. P Natl Acad Sci USA 104: 12288-12293.
    • (2007) P Natl Acad Sci USA , vol.104 , pp. 12288-12293
    • Lu, J.1    Chew, E.H.2    Holmgren, A.3
  • 144
    • 0035861588 scopus 로고    scopus 로고
    • Manganese superoxide dismutase in Saccharomyces cerevisiae acquires its metal co-factor through a pathway involving the Nramp metal transporter, Smf2p
    • Luk EE & Culotta VC. (2001) Manganese superoxide dismutase in Saccharomyces cerevisiae acquires its metal co-factor through a pathway involving the Nramp metal transporter, Smf2p. J Biol Chem 276: 47556-47562.
    • (2001) J Biol Chem , vol.276 , pp. 47556-47562
    • Luk, E.E.1    Culotta, V.C.2
  • 148
    • 0034660257 scopus 로고    scopus 로고
    • Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae
    • MacDiarmid CW, Gaither LA & Eide D. (2000) Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae. EMBO J 19: 2845-2855.
    • (2000) EMBO J , vol.19 , pp. 2845-2855
    • MacDiarmid, C.W.1    Gaither, L.A.2    Eide, D.3
  • 149
    • 0037131363 scopus 로고    scopus 로고
    • Biochemical properties of vacuolar zinc transport systems of Saccharomyces cerevisiae
    • MacDiarmid CW, Milanick MA & Eide DJ. (2002) Biochemical properties of vacuolar zinc transport systems of Saccharomyces cerevisiae. J Biol Chem 277: 39187-39194.
    • (2002) J Biol Chem , vol.277 , pp. 39187-39194
    • MacDiarmid, C.W.1    Milanick, M.A.2    Eide, D.J.3
  • 151
    • 4344689976 scopus 로고    scopus 로고
    • Arsenical resistance genes in Saccharomyces douglasii and other yeast species undergo rapid evolution involving genomic rearrangements and duplications
    • Maciaszczyk E, Wysocki R, Golik P, Lazowska J & Ulaszewski S. (2004) Arsenical resistance genes in Saccharomyces douglasii and other yeast species undergo rapid evolution involving genomic rearrangements and duplications. FEMS Yeast Res 4: 821-832.
    • (2004) FEMS Yeast Res , vol.4 , pp. 821-832
    • Maciaszczyk, E.1    Wysocki, R.2    Golik, P.3    Lazowska, J.4    Ulaszewski, S.5
  • 152
    • 1242312888 scopus 로고    scopus 로고
    • Localization and functional characterization of metal-binding sites in phytochelatin synthases
    • Maier T, Yu C, Kullertz G & Clemens S. (2003) Localization and functional characterization of metal-binding sites in phytochelatin synthases. Planta 218: 300-308.
    • (2003) Planta , vol.218 , pp. 300-308
    • Maier, T.1    Yu, C.2    Kullertz, G.3    Clemens, S.4
  • 153
    • 0000958553 scopus 로고    scopus 로고
    • The composition of metals bound to class III metallothionein (phytochelatin and its desglycyl peptide) induced by various metals in root cultures of Rubia tinctorum
    • Maitani T, Kubota H, Sato K & Yamada T. (1996) The composition of metals bound to class III metallothionein (phytochelatin and its desglycyl peptide) induced by various metals in root cultures of Rubia tinctorum. Plant Physiol 110: 1145-1150.
    • (1996) Plant Physiol , vol.110 , pp. 1145-1150
    • Maitani, T.1    Kubota, H.2    Sato, K.3    Yamada, T.4
  • 156
    • 11144273952 scopus 로고    scopus 로고
    • TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1
    • Martin DE, Soulard A & Hall MN. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119: 969-979.
    • (2004) Cell , vol.119 , pp. 969-979
    • Martin, D.E.1    Soulard, A.2    Hall, M.N.3
  • 157
    • 0029879360 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE)
    • Martinez-Pastor MT, Marchler G, Schuller C, Marchler-Bauer A, Ruis H & Estruch F. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J 15: 2227-2235.
    • (1996) EMBO J , vol.15 , pp. 2227-2235
    • Martinez-Pastor, M.T.1    Marchler, G.2    Schuller, C.3    Marchler-Bauer, A.4    Ruis, H.5    Estruch, F.6
  • 158
    • 0036911113 scopus 로고    scopus 로고
    • Requirement of the N-terminal extension for vacuolar trafficking and transport activity of yeast Ycf1p, an ATP-binding cassette transporter
    • Mason DL & Michaelis S. (2002) Requirement of the N-terminal extension for vacuolar trafficking and transport activity of yeast Ycf1p, an ATP-binding cassette transporter. Mol Biol Cell 13: 4443-4455.
    • (2002) Mol Biol Cell , vol.13 , pp. 4443-4455
    • Mason, D.L.1    Michaelis, S.2
  • 159
    • 0038143251 scopus 로고    scopus 로고
    • A region within a lumenal loop of Saccharomyces cerevisiae Ycf1p directs proteolytic processing and substrate specificity
    • Mason DL, Mallampalli MP, Huyer G & Michaelis S. (2003) A region within a lumenal loop of Saccharomyces cerevisiae Ycf1p directs proteolytic processing and substrate specificity. Eukaryot Cell 2: 588-598.
    • (2003) Eukaryot Cell , vol.2 , pp. 588-598
    • Mason, D.L.1    Mallampalli, M.P.2    Huyer, G.3    Michaelis, S.4
  • 160
    • 77949425114 scopus 로고    scopus 로고
    • Pentavalent methylated arsenicals are substrates of human AQP9
    • McDermott JR, Jiang X, Beene LC, Rosen BP & Liu Z. (2010) Pentavalent methylated arsenicals are substrates of human AQP9. Biometals 23: 119-127.
    • (2010) Biometals , vol.23 , pp. 119-127
    • McDermott, J.R.1    Jiang, X.2    Beene, L.C.3    Rosen, B.P.4    Liu, Z.5
  • 161
    • 0038419826 scopus 로고    scopus 로고
    • Cancer, cadmium and genome integrity
    • McMurray CT & Tainer JA. (2003) Cancer, cadmium and genome integrity. Nat Genet 34: 239-241.
    • (2003) Nat Genet , vol.34 , pp. 239-241
    • McMurray, C.T.1    Tainer, J.A.2
  • 162
    • 50249175909 scopus 로고    scopus 로고
    • Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins
    • Medicherla B & Goldberg AL. (2008) Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins. J Cell Biol 182: 663-673.
    • (2008) J Cell Biol , vol.182 , pp. 663-673
    • Medicherla, B.1    Goldberg, A.L.2
  • 163
    • 33744954063 scopus 로고    scopus 로고
    • Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor
    • Menant A, Baudouin-Cornu P, Peyraud C, Tyers M & Thomas D. (2006) Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor. J Biol Chem 281: 11744-11754.
    • (2006) J Biol Chem , vol.281 , pp. 11744-11754
    • Menant, A.1    Baudouin-Cornu, P.2    Peyraud, C.3    Tyers, M.4    Thomas, D.5
  • 165
    • 50949128387 scopus 로고    scopus 로고
    • Contribution of Yap1 towards Saccharomyces cerevisiae adaptation to arsenic-mediated oxidative stress
    • Menezes RA, Amaral C, Batista-Nascimento L et al (2008) Contribution of Yap1 towards Saccharomyces cerevisiae adaptation to arsenic-mediated oxidative stress. Biochem J 414: 301-311.
    • (2008) Biochem J , vol.414 , pp. 301-311
    • Menezes, R.A.1    Amaral, C.2    Batista-Nascimento, L.3
  • 166
    • 2442605626 scopus 로고    scopus 로고
    • As(III) and Sb(III) uptake by GlpF and efflux by ArsB in Escherichia coli
    • Meng YL, Liu Z & Rosen BP. (2004) As(III) and Sb(III) uptake by GlpF and efflux by ArsB in Escherichia coli. J Biol Chem 279: 18334-18341.
    • (2004) J Biol Chem , vol.279 , pp. 18334-18341
    • Meng, Y.L.1    Liu, Z.2    Rosen, B.P.3
  • 167
    • 0033063434 scopus 로고    scopus 로고
    • Arsenic binding proteins from human lymphoblastoid cells
    • Menzel DB, Hamadeh HK, Lee E et al (1999) Arsenic binding proteins from human lymphoblastoid cells. Toxicol Lett 105: 89-101.
    • (1999) Toxicol Lett , vol.105 , pp. 89-101
    • Menzel, D.B.1    Hamadeh, H.K.2    Lee, E.3
  • 169
    • 48949105449 scopus 로고    scopus 로고
    • Mitogenactivated protein kinase Hog1 mediates adaptation to G1 checkpoint arrest during arsenite and hyperosmotic stress
    • Migdal I, Ilina Y, Tamás MJ & Wysocki R. (2008) Mitogenactivated protein kinase Hog1 mediates adaptation to G1 checkpoint arrest during arsenite and hyperosmotic stress. Eukaryot Cell 7: 1309-1317.
    • (2008) Eukaryot Cell , vol.7 , pp. 1309-1317
    • Migdal, I.1    Ilina, Y.2    Tamás, M.J.3    Wysocki, R.4
  • 170
    • 34548775911 scopus 로고    scopus 로고
    • Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid
    • Mollapour M & Piper PW. (2007) Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid. Mol Cell Biol 27: 6446-6456.
    • (2007) Mol Cell Biol , vol.27 , pp. 6446-6456
    • Mollapour, M.1    Piper, P.W.2
  • 171
    • 0035657776 scopus 로고    scopus 로고
    • Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium
    • Momose Y & Iwahashi H. (2001) Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium. Environ Toxicol Chem 20: 2353-2360.
    • (2001) Environ Toxicol Chem , vol.20 , pp. 2353-2360
    • Momose, Y.1    Iwahashi, H.2
  • 172
    • 0024638464 scopus 로고
    • Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins
    • Moye-Rowley WS, Harshman KD & Parker CS. (1989) Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins. Gene Dev 3: 283-292.
    • (1989) Gene Dev , vol.3 , pp. 283-292
    • Moye-Rowley, W.S.1    Harshman, K.D.2    Parker, C.S.3
  • 173
    • 0031769690 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae ACR2 gene encodes an arsenate reductase
    • Mukhopadhyay R & Rosen BP. (1998) Saccharomyces cerevisiae ACR2 gene encodes an arsenate reductase. FEMS Microbiol Lett 168: 127-136.
    • (1998) FEMS Microbiol Lett , vol.168 , pp. 127-136
    • Mukhopadhyay, R.1    Rosen, B.P.2
  • 174
    • 0035860779 scopus 로고    scopus 로고
    • The phosphatase C(X)5R motif is required for catalytic activity of the Saccharomyces cerevisiae Acr2p arsenate reductase
    • Mukhopadhyay R & Rosen BP. (2001) The phosphatase C(X)5R motif is required for catalytic activity of the Saccharomyces cerevisiae Acr2p arsenate reductase. J Biol Chem 276: 34738-34742.
    • (2001) J Biol Chem , vol.276 , pp. 34738-34742
    • Mukhopadhyay, R.1    Rosen, B.P.2
  • 175
    • 0034647748 scopus 로고    scopus 로고
    • Purification and characterization of Acr2p, the Saccharomyces cerevisiae arsenate reductase
    • Mukhopadhyay R, Shi J & Rosen BP. (2000) Purification and characterization of Acr2p, the Saccharomyces cerevisiae arsenate reductase. J Biol Chem 275: 21149-21157.
    • (2000) J Biol Chem , vol.275 , pp. 21149-21157
    • Mukhopadhyay, R.1    Shi, J.2    Rosen, B.P.3
  • 176
    • 0042591267 scopus 로고    scopus 로고
    • Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase
    • Mukhopadhyay R, Zhou Y & Rosen BP. (2003) Directed evolution of a yeast arsenate reductase into a protein-tyrosine phosphatase. J Biol Chem 278: 24476-24480.
    • (2003) J Biol Chem , vol.278 , pp. 24476-24480
    • Mukhopadhyay, R.1    Zhou, Y.2    Rosen, B.P.3
  • 177
    • 0034012498 scopus 로고    scopus 로고
    • GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae
    • Naganuma A, Miura N, Kaneko S et al (2000) GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae. FASEB J 14: 968-972.
    • (2000) FASEB J , vol.14 , pp. 968-972
    • Naganuma, A.1    Miura, N.2    Kaneko, S.3
  • 179
    • 0035846932 scopus 로고    scopus 로고
    • Multiple Yap1pbinding sites mediate induction of the yeast major facilitator FLR1 gene in response to drugs, oxidants, and alkylating agents
    • Nguyen DT, Alarco AM & Raymond M. (2001) Multiple Yap1pbinding sites mediate induction of the yeast major facilitator FLR1 gene in response to drugs, oxidants, and alkylating agents. J Biol Chem 276: 1138-1145.
    • (2001) J Biol Chem , vol.276 , pp. 1138-1145
    • Nguyen, D.T.1    Alarco, A.M.2    Raymond, M.3
  • 180
    • 57049101734 scopus 로고    scopus 로고
    • Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1
    • Nikko E, Sullivan JA & Pelham HR. (2008) Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1. EMBO Rep 9: 1216-1221.
    • (2008) EMBO Rep , vol.9 , pp. 1216-1221
    • Nikko, E.1    Sullivan, J.A.2    Pelham, H.R.3
  • 182
    • 0026660329 scopus 로고
    • Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter
    • Ortiz DF, Kreppel L, Speiser DM, Scheel G, McDonald G & Ow DW. (1992) Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter. EMBO J 11: 3491-3499.
    • (1992) EMBO J , vol.11 , pp. 3491-3499
    • Ortiz, D.F.1    Kreppel, L.2    Speiser, D.M.3    Scheel, G.4    McDonald, G.5    Ow, D.W.6
  • 183
    • 0028924272 scopus 로고
    • Transport of metal-binding peptides by HMT1, a fission yeast ABC-type vacuolar membrane protein
    • Ortiz DF, Ruscitti T, McCue KF & Ow DW. (1995) Transport of metal-binding peptides by HMT1, a fission yeast ABC-type vacuolar membrane protein. J Biol Chem 270: 4721-4728.
    • (1995) J Biol Chem , vol.270 , pp. 4721-4728
    • Ortiz, D.F.1    Ruscitti, T.2    McCue, K.F.3    Ow, D.W.4
  • 184
    • 0004317556 scopus 로고
    • Molecular genetic analysis of cadmium tolerance in Schizosaccharomyces pombe
    • (Winkelmann G & Winge DR, eds), Marcel Dekker Inc., New York
    • Ow DW, Ortiz DF, Speiser DM & Mc Cue KF. (1994) Molecular genetic analysis of cadmium tolerance in Schizosaccharomyces pombe. Metal Ions in Fungi, Vol. 2 (Winkelmann G & Winge DR, eds), pp. 339-359. Marcel Dekker Inc., New York.
    • (1994) Metal Ions in Fungi, Vol. 2 , pp. 339-359
    • Ow, D.W.1    Ortiz, D.F.2    Speiser, D.M.3    Mc Cue, K.F.4
  • 185
    • 0036226237 scopus 로고    scopus 로고
    • Control of 26S proteasome expression by transcription factors regulating multidrug resistance in Saccharomyces cerevisiae
    • Owsianik G, Balzi E & Ghislain M. (2002) Control of 26S proteasome expression by transcription factors regulating multidrug resistance in Saccharomyces cerevisiae. Mol Microbiol 43: 1295-1308.
    • (2002) Mol Microbiol , vol.43 , pp. 1295-1308
    • Owsianik, G.1    Balzi, E.2    Ghislain, M.3
  • 186
    • 33845693008 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Crs5 metallothionein metal-binding abilities and its role in the response to zinc overload
    • Pagani A, Villarreal L, Capdevila M & Atrian S. (2007) The Saccharomyces cerevisiae Crs5 metallothionein metal-binding abilities and its role in the response to zinc overload. Mol Microbiol 63: 256-269.
    • (2007) Mol Microbiol , vol.63 , pp. 256-269
    • Pagani, A.1    Villarreal, L.2    Capdevila, M.3    Atrian, S.4
  • 187
    • 0033623909 scopus 로고    scopus 로고
    • SSU1 mediates sulphite efflux in Saccharomyces cerevisiae
    • Park H & Bakalinsky AT. (2000) SSU1 mediates sulphite efflux in Saccharomyces cerevisiae. Yeast 16: 881-888.
    • (2000) Yeast , vol.16 , pp. 881-888
    • Park, H.1    Bakalinsky, A.T.2
  • 188
    • 0034599725 scopus 로고    scopus 로고
    • SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition
    • Patton EE, Peyraud C, Rouillon A, Surdin-Kerjan Y, Tyers M & Thomas D. (2000) SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition. EMBO J 19: 1613-1624.
    • (2000) EMBO J , vol.19 , pp. 1613-1624
    • Patton, E.E.1    Peyraud, C.2    Rouillon, A.3    Surdin-Kerjan, Y.4    Tyers, M.5    Thomas, D.6
  • 189
    • 60549093028 scopus 로고    scopus 로고
    • Chemical dissection of an essential redox switch in yeast
    • Paulsen CE & Carroll KS. (2009) Chemical dissection of an essential redox switch in yeast. Chem Biol 16: 217-225.
    • (2009) Chem Biol , vol.16 , pp. 217-225
    • Paulsen, C.E.1    Carroll, K.S.2
  • 190
    • 0030953624 scopus 로고    scopus 로고
    • A novel family of ubiquitous heavy metal ion transport proteins
    • Paulsen IT & Saier MH Jr. (1997) A novel family of ubiquitous heavy metal ion transport proteins. J Membrane Biol 156: 99-103.
    • (1997) J Membrane Biol , vol.156 , pp. 99-103
    • Paulsen, I.T.1    Saier M.H., Jr.2
  • 191
    • 34147167177 scopus 로고    scopus 로고
    • Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast twohybrid analysis
    • Paumi CM, Menendez J, Arnoldo A et al (2007) Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast twohybrid analysis. Mol Cell 26: 15-25.
    • (2007) Mol Cell , vol.26 , pp. 15-25
    • Paumi, C.M.1    Menendez, J.2    Arnoldo, A.3
  • 192
    • 55249120230 scopus 로고    scopus 로고
    • Negative regulation of the yeast ABC transporter Ycf1p by phosphorylation within its N-terminal extension
    • Paumi CM, Chuk M, Chevelev I, Stagljar I & Michaelis S. (2008) Negative regulation of the yeast ABC transporter Ycf1p by phosphorylation within its N-terminal extension. J Biol Chem 283: 27079-27088.
    • (2008) J Biol Chem , vol.283 , pp. 27079-27088
    • Paumi, C.M.1    Chuk, M.2    Chevelev, I.3    Stagljar, I.4    Michaelis, S.5
  • 193
    • 71449097048 scopus 로고    scopus 로고
    • ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily
    • Paumi CM, Chuk M, Snider J, Stagljar I & Michaelis S. (2009) ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily. Microbiol Mol Biol R 73: 577-593.
    • (2009) Microbiol Mol Biol R , vol.73 , pp. 577-593
    • Paumi, C.M.1    Chuk, M.2    Snider, J.3    Stagljar, I.4    Michaelis, S.5
  • 196
    • 0034116016 scopus 로고    scopus 로고
    • Identification of genes affecting selenite toxicity and resistance in Saccharomyces cerevisiae
    • Pinson B, Sagot I & Daignan-Fornier B. (2000) Identification of genes affecting selenite toxicity and resistance in Saccharomyces cerevisiae. Mol Microbiol 36: 679-687.
    • (2000) Mol Microbiol , vol.36 , pp. 679-687
    • Pinson, B.1    Sagot, I.2    Daignan-Fornier, B.3
  • 197
    • 4143144191 scopus 로고    scopus 로고
    • Low affinity orthophosphate carriers regulate PHO gene expression independently of internal orthophosphate concentration in Saccharomyces cerevisiae
    • Pinson B, Merle M, Franconi JM & Daignan-Fornier B. (2004) Low affinity orthophosphate carriers regulate PHO gene expression independently of internal orthophosphate concentration in Saccharomyces cerevisiae. J Biol Chem 279: 35273-35280.
    • (2004) J Biol Chem , vol.279 , pp. 35273-35280
    • Pinson, B.1    Merle, M.2    Franconi, J.M.3    Daignan-Fornier, B.4
  • 199
    • 35148901172 scopus 로고    scopus 로고
    • 3 with glycerol: implications for their uptake
    • 3 with glycerol: implications for their uptake. Chem Res Toxicol 20: 1269-1276.
    • (2007) Chem Res Toxicol , vol.20 , pp. 1269-1276
    • Porquet, A.1    Filella, M.2
  • 200
    • 0033773040 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae expresses three functionally distinct homologues of the Nramp family of metal transporters
    • Portnoy ME, Liu XF & Culotta VC. (2000) Saccharomyces cerevisiae expresses three functionally distinct homologues of the Nramp family of metal transporters. Mol Cell Biol 20: 7893-7902.
    • (2000) Mol Cell Biol , vol.20 , pp. 7893-7902
    • Portnoy, M.E.1    Liu, X.F.2    Culotta, V.C.3
  • 201
    • 33750979528 scopus 로고    scopus 로고
    • Metal(loid)s and radionuclides cytotoxicity in Saccharomyces cerevisiae. Role of YCF1, glutathione and effect of buthionine sulfoximine
    • Preveral S, Ansoborlo E, Mari S, Vavasseur A & Forestier C. (2006) Metal(loid)s and radionuclides cytotoxicity in Saccharomyces cerevisiae. Role of YCF1, glutathione and effect of buthionine sulfoximine. Biochimie 88: 1651-1663.
    • (2006) Biochimie , vol.88 , pp. 1651-1663
    • Preveral, S.1    Ansoborlo, E.2    Mari, S.3    Vavasseur, A.4    Forestier, C.5
  • 202
    • 64149128635 scopus 로고    scopus 로고
    • A common highly conserved cadmium detoxification mechanism from bacteria to humans: heavy metal tolerance conferred by the ATPbinding cassette (ABC) transporter SpHMT1 requires glutathione but not metal-chelating phytochelatin peptides
    • Preveral S, Gayet L, Moldes C et al (2009) A common highly conserved cadmium detoxification mechanism from bacteria to humans: heavy metal tolerance conferred by the ATPbinding cassette (ABC) transporter SpHMT1 requires glutathione but not metal-chelating phytochelatin peptides. J Biol Chem 284: 4936-4943.
    • (2009) J Biol Chem , vol.284 , pp. 4936-4943
    • Preveral, S.1    Gayet, L.2    Moldes, C.3
  • 204
    • 11144354454 scopus 로고    scopus 로고
    • Experimental and theoretical characterization of arsenite in water: insights into the coordination environment of As-O
    • Ramirez-Solis A, Mukopadhyay R, Rosen BP & Stemmler TL. (2004) Experimental and theoretical characterization of arsenite in water: insights into the coordination environment of As-O. Inorg Chem 43: 2954-2959.
    • (2004) Inorg Chem , vol.43 , pp. 2954-2959
    • Ramirez-Solis, A.1    Mukopadhyay, R.2    Rosen, B.P.3    Stemmler, T.L.4
  • 205
    • 23844453642 scopus 로고    scopus 로고
    • Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe
    • Rodriguez-Gabriel MA & Russell P. (2005) Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe. Eukaryot Cell 4: 1396-1402.
    • (2005) Eukaryot Cell , vol.4 , pp. 1396-1402
    • Rodriguez-Gabriel, M.A.1    Russell, P.2
  • 206
    • 0033134885 scopus 로고    scopus 로고
    • Families of arsenic transporters
    • Rosen BP. (1999) Families of arsenic transporters. Trends Microbiol 7: 207-212.
    • (1999) Trends Microbiol , vol.7 , pp. 207-212
    • Rosen, B.P.1
  • 208
    • 47149118006 scopus 로고    scopus 로고
    • Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast
    • Ruotolo R, Marchini G & Ottonello S. (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9: R67.
    • (2008) Genome Biol , vol.9
    • Ruotolo, R.1    Marchini, G.2    Ottonello, S.3
  • 209
    • 51249112751 scopus 로고    scopus 로고
    • Arsenic-eaters: by accident or by design
    • Salt DE & Norton GJ. (2008) Arsenic-eaters: by accident or by design. New Phytol 180: 8-11.
    • (2008) New Phytol , vol.180 , pp. 8-11
    • Salt, D.E.1    Norton, G.J.2
  • 210
    • 0037352431 scopus 로고    scopus 로고
    • Reactive oxygen species are involved in arsenic trioxide inhibition of pyruvate dehydrogenase activity
    • Samikkannu T, Chen CH, Yih LH, Wang AS, Lin SY, Chen TC & Jan KY. (2003) Reactive oxygen species are involved in arsenic trioxide inhibition of pyruvate dehydrogenase activity. Chem Res Toxicol 16: 409-414.
    • (2003) Chem Res Toxicol , vol.16 , pp. 409-414
    • Samikkannu, T.1    Chen, C.H.2    Yih, L.H.3    Wang, A.S.4    Lin, S.Y.5    Chen, T.C.6    Jan, K.Y.7
  • 211
    • 0030953720 scopus 로고    scopus 로고
    • Antimonite is accumulated by the glycerol facilitator GlpF in Escherichia coli
    • Sanders OI, Rensing C, Kuroda M, Mitra B & Rosen BP. (1997) Antimonite is accumulated by the glycerol facilitator GlpF in Escherichia coli. J Bacteriol 179: 3365-3367.
    • (1997) J Bacteriol , vol.179 , pp. 3365-3367
    • Sanders, O.I.1    Rensing, C.2    Kuroda, M.3    Mitra, B.4    Rosen, B.P.5
  • 212
    • 33645130011 scopus 로고    scopus 로고
    • Glucose signaling in Saccharomyces cerevisiae
    • Santangelo GM. (2006) Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol R 70: 253-282.
    • (2006) Microbiol Mol Biol R , vol.70 , pp. 253-282
    • Santangelo, G.M.1
  • 213
    • 0031896498 scopus 로고    scopus 로고
    • The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite
    • Sato T & Kobayashi Y. (1998) The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite. J Bacteriol 180: 1655-1661.
    • (1998) J Bacteriol , vol.180 , pp. 1655-1661
    • Sato, T.1    Kobayashi, Y.2
  • 214
    • 65049087704 scopus 로고    scopus 로고
    • 2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2. Biochem Bioph Res Co
    • 2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2. Biochem Bioph Res Co 383: 198-202.
    • (2009) , vol.383 , pp. 198-202
    • Schmidt, K.1    Wolfe, D.M.2    Stiller, B.3    Pearce, D.A.4
  • 215
    • 0030003064 scopus 로고    scopus 로고
    • Msn2p, a zinc finger DNAbinding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae
    • Schmitt AP & McEntee K. (1996) Msn2p, a zinc finger DNAbinding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae. P Natl Acad Sci USA 93: 5777-5782.
    • (1996) P Natl Acad Sci USA , vol.93 , pp. 5777-5782
    • Schmitt, A.P.1    McEntee, K.2
  • 216
    • 0033765224 scopus 로고    scopus 로고
    • Detoxification of arsenic by phytochelatins in plants
    • Schmoger ME, OvenM& Grill E. (2000) Detoxification of arsenic by phytochelatins in plants. Plant Physiol 122: 793-801.
    • (2000) Plant Physiol , vol.122 , pp. 793-801
    • Schmoger, M.E.1    Oven, M.2    Grill, E.3
  • 217
    • 0036001088 scopus 로고    scopus 로고
    • Plant responses to abiotic stresses: heavy metal-induced oxidative stress and protection by mycorrhization
    • Schützendübel A & Polle A. (2002) Plant responses to abiotic stresses: heavy metal-induced oxidative stress and protection by mycorrhization. J Exp Bot 53: 1351-1365.
    • (2002) J Exp Bot , vol.53 , pp. 1351-1365
    • Schützendübel, A.1    Polle, A.2
  • 218
    • 0031228020 scopus 로고    scopus 로고
    • Active oxygen generation as a possible mechanism of selenium toxicity
    • Seko Y & Imura N. (1997) Active oxygen generation as a possible mechanism of selenium toxicity. Biomed Environ Sci 10: 333-339.
    • (1997) Biomed Environ Sci , vol.10 , pp. 333-339
    • Seko, Y.1    Imura, N.2
  • 219
    • 46849091133 scopus 로고    scopus 로고
    • Yeast genes involved in cadmium tolerance: identification of DNA replication as a target of cadmium toxicity
    • Serero A, Lopes J, Nicolas A & Boiteux S. (2008) Yeast genes involved in cadmium tolerance: identification of DNA replication as a target of cadmium toxicity. DNA Repair 7: 1262-1275.
    • (2008) DNA Repair , vol.7 , pp. 1262-1275
    • Serero, A.1    Lopes, J.2    Nicolas, A.3    Boiteux, S.4
  • 220
    • 12144289449 scopus 로고    scopus 로고
    • Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae
    • Shakoury-Elizeh M, Tiedeman J, Rashford J et al (2004) Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Mol Biol Cell 15: 1233-1243.
    • (2004) Mol Biol Cell , vol.15 , pp. 1233-1243
    • Shakoury-Elizeh, M.1    Tiedeman, J.2    Rashford, J.3
  • 221
    • 0036616623 scopus 로고    scopus 로고
    • Localization, regulation, and substrate transport properties of Bpt1p, a Saccharomyces cerevisiae MRP-type ABC transporter
    • Sharma KG, Mason DL, Liu G, Rea PA, Bachhawat AK & Michaelis S. (2002) Localization, regulation, and substrate transport properties of Bpt1p, a Saccharomyces cerevisiae MRP-type ABC transporter. Eukaryot Cell 1: 391-400.
    • (2002) Eukaryot Cell , vol.1 , pp. 391-400
    • Sharma, K.G.1    Mason, D.L.2    Liu, G.3    Rea, P.A.4    Bachhawat, A.K.5    Michaelis, S.6
  • 222
    • 44649091898 scopus 로고    scopus 로고
    • Heavy metal ions are potent inhibitors of protein folding
    • Sharma SK, Goloubinoff P & Christen P. (2008) Heavy metal ions are potent inhibitors of protein folding. Biochem Bioph Res Co 372: 341-345.
    • (2008) Biochem Bioph Res Co , vol.372 , pp. 341-345
    • Sharma, S.K.1    Goloubinoff, P.2    Christen, P.3
  • 223
    • 0742289410 scopus 로고    scopus 로고
    • Oxidative mechanism of arsenic toxicity and carcinogenesis
    • Shi H, Shi X & Liu KJ. (2004) Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem 255: 67-78.
    • (2004) Mol Cell Biochem , vol.255 , pp. 67-78
    • Shi, H.1    Shi, X.2    Liu, K.J.3
  • 224
    • 0027998060 scopus 로고
    • Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fentonlike reaction
    • Shi X, Mao Y, Knapton AD et al (1994) Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fentonlike reaction. Carcinogenesis 15: 2475-2478.
    • (1994) Carcinogenesis , vol.15 , pp. 2475-2478
    • Shi, X.1    Mao, Y.2    Knapton, A.D.3
  • 225
    • 0034062984 scopus 로고    scopus 로고
    • The cadmium-resistant gene, CAD2, which is a mutated putative copper-transporter gene (PCA1), controls the intracellular cadmium-level in the yeast S. cerevisiae
    • Shiraishi E, Inouhe M, Joho M & Tohoyama H. (2000) The cadmium-resistant gene, CAD2, which is a mutated putative copper-transporter gene (PCA1), controls the intracellular cadmium-level in the yeast S. cerevisiae. Curr Genet 37: 79-86.
    • (2000) Curr Genet , vol.37 , pp. 79-86
    • Shiraishi, E.1    Inouhe, M.2    Joho, M.3    Tohoyama, H.4
  • 226
    • 4344587177 scopus 로고    scopus 로고
    • A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans
    • Smith DA, Nicholls S, Morgan BA, Brown AJ & Quinn J. (2004) A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans. Mol Biol Cell 15: 4179-4190.
    • (2004) Mol Biol Cell , vol.15 , pp. 4179-4190
    • Smith, D.A.1    Nicholls, S.2    Morgan, B.A.3    Brown, A.J.4    Quinn, J.5
  • 227
    • 0043208901 scopus 로고    scopus 로고
    • Engineering tolerance and accumulation of lead and cadmium in transgenic plants
    • Song WY, Sohn EJ, Martinoia E et al (2003) Engineering tolerance and accumulation of lead and cadmium in transgenic plants. Nat Biotechnol 21: 914-919.
    • (2003) Nat Biotechnol , vol.21 , pp. 914-919
    • Song, W.Y.1    Sohn, E.J.2    Martinoia, E.3
  • 228
    • 58649091123 scopus 로고    scopus 로고
    • Drosophila ABC transporter, DmHMT-1, confers tolerance to cadmium. DmHMT-1 and its yeast homolog, SpHMT-1, are not essential for vacuolar phytochelatin sequestration
    • Sooksa-Nguan T, Yakubov B, Kozlovskyy VI et al (2009) Drosophila ABC transporter, DmHMT-1, confers tolerance to cadmium. DmHMT-1 and its yeast homolog, SpHMT-1, are not essential for vacuolar phytochelatin sequestration. J Biol Chem 284: 354-362.
    • (2009) J Biol Chem , vol.284 , pp. 354-362
    • Sooksa-Nguan, T.1    Yakubov, B.2    Kozlovskyy, V.I.3
  • 229
    • 33750290326 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase Hog1 is essential for the response to arsenite in Saccharomyces cerevisiae
    • Sotelo J & Rodriguez-Gabriel MA. (2006) Mitogen-activated protein kinase Hog1 is essential for the response to arsenite in Saccharomyces cerevisiae. Eukaryot Cell 5: 1826-1830.
    • (2006) Eukaryot Cell , vol.5 , pp. 1826-1830
    • Sotelo, J.1    Rodriguez-Gabriel, M.A.2
  • 231
    • 0037131163 scopus 로고    scopus 로고
    • The yeast iron regulon is induced upon cobalt stress and crucial for cobalt tolerance
    • Stadler JA & Schweyen RJ. (2002) The yeast iron regulon is induced upon cobalt stress and crucial for cobalt tolerance. J Biol Chem 277: 39649-39654.
    • (2002) J Biol Chem , vol.277 , pp. 39649-39654
    • Stadler, J.A.1    Schweyen, R.J.2
  • 232
    • 33748439489 scopus 로고    scopus 로고
    • An arseniteinducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity
    • Stanhill A, Haynes CM, Zhang Yet al (2006) An arseniteinducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity. Mol Cell 23: 875-885.
    • (2006) Mol Cell , vol.23 , pp. 875-885
    • Stanhill, A.1    Haynes, C.M.2    Zhang Yet, al.3
  • 233
    • 0031034766 scopus 로고    scopus 로고
    • Amino acid-dependent regulation of the Saccharomyces cerevisiae GSH1 gene by hydrogen peroxide
    • Stephen DW & Jamieson DJ. (1997) Amino acid-dependent regulation of the Saccharomyces cerevisiae GSH1 gene by hydrogen peroxide. Mol Microbiol 23: 203-210.
    • (1997) Mol Microbiol , vol.23 , pp. 203-210
    • Stephen, D.W.1    Jamieson, D.J.2
  • 234
    • 0029013534 scopus 로고
    • The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae
    • Stephen DW, Rivers SL & Jamieson DJ. (1995) The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae. Mol Microbiol 16: 415-423.
    • (1995) Mol Microbiol , vol.16 , pp. 415-423
    • Stephen, D.W.1    Rivers, S.L.2    Jamieson, D.J.3
  • 235
    • 0037462651 scopus 로고    scopus 로고
    • Degradation of transcription factor Nrf2 via the ubiquitinproteasome pathway and stabilization by cadmium
    • Stewart D, Killeen E, Naquin R, Alam S & Alam J. (2003) Degradation of transcription factor Nrf2 via the ubiquitinproteasome pathway and stabilization by cadmium. J Biol Chem 278: 2396-2402.
    • (2003) J Biol Chem , vol.278 , pp. 2396-2402
    • Stewart, D.1    Killeen, E.2    Naquin, R.3    Alam, S.4    Alam, J.5
  • 236
    • 33644543442 scopus 로고    scopus 로고
    • Transferrin receptor-like proteins control the degradation of a yeast metal transporter
    • Stimpson HE, Lewis MJ & Pelham HR. (2006) Transferrin receptor-like proteins control the degradation of a yeast metal transporter. EMBO J 25: 662-672.
    • (2006) EMBO J , vol.25 , pp. 662-672
    • Stimpson, H.E.1    Lewis, M.J.2    Pelham, H.R.3
  • 237
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • Stohs SJ & Bagchi D. (1995) Oxidative mechanisms in the toxicity of metal ions. Free Radical Bio Med 18: 321-336.
    • (1995) Free Radical Bio Med , vol.18 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 238
    • 18144409486 scopus 로고    scopus 로고
    • The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle
    • Su NY, Flick K & Kaiser P. (2005) The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle. Mol Cell Biol 25: 3875-3885.
    • (2005) Mol Cell Biol , vol.25 , pp. 3875-3885
    • Su, N.Y.1    Flick, K.2    Kaiser, P.3
  • 239
    • 34347379169 scopus 로고    scopus 로고
    • Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase Rsp5 to membrane proteins in vivo and in vitro
    • Sullivan JA, Lewis MJ, Nikko E & Pelham HR. (2007) Multiple interactions drive adaptor-mediated recruitment of the ubiquitin ligase Rsp5 to membrane proteins in vivo and in vitro. Mol Biol Cell 18: 2429-2440.
    • (2007) Mol Biol Cell , vol.18 , pp. 2429-2440
    • Sullivan, J.A.1    Lewis, M.J.2    Nikko, E.3    Pelham, H.R.4
  • 240
    • 63749128999 scopus 로고    scopus 로고
    • Damage control: regulating defenses against toxic metals and metalloids
    • Summers AO. (2009) Damage control: regulating defenses against toxic metals and metalloids. Curr Opin Microbiol 12: 138-144.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 138-144
    • Summers, A.O.1
  • 242
    • 9944233496 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione metabolism in astrocytes by Nrf2
    • Sun X, Erb H & Murphy TH. (2005) Coordinate regulation of glutathione metabolism in astrocytes by Nrf2. Biochem Bioph Res Co 326: 371-377.
    • (2005) Biochem Bioph Res Co , vol.326 , pp. 371-377
    • Sun, X.1    Erb, H.2    Murphy, T.H.3
  • 243
    • 0029978512 scopus 로고    scopus 로고
    • A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria
    • Supek F, Supekova L, Nelson H & Nelson N. (1996) A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria. P Natl Acad Sci USA 93: 5105-5110.
    • (1996) P Natl Acad Sci USA , vol.93 , pp. 5105-5110
    • Supek, F.1    Supekova, L.2    Nelson, H.3    Nelson, N.4
  • 244
    • 0028064872 scopus 로고
    • A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance- associated protein
    • Szczypka MS, Wemmie JA, Moye-Rowley WS & Thiele DJ. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance- associated protein. J Biol Chem 269: 22853-22857.
    • (1994) J Biol Chem , vol.269 , pp. 22853-22857
    • Szczypka, M.S.1    Wemmie, J.A.2    Moye-Rowley, W.S.3    Thiele, D.J.4
  • 246
    • 0033063643 scopus 로고    scopus 로고
    • Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation
    • Tamás MJ, Luyten K, Sutherland FC et al (1999) Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation. Mol Microbiol 31: 1087-1104.
    • (1999) Mol Microbiol , vol.31 , pp. 1087-1104
    • Tamás, M.J.1    Luyten, K.2    Sutherland, F.C.3
  • 247
    • 0037458556 scopus 로고    scopus 로고
    • A short regulatory domain restricts glycerol transport through yeast Fps1p
    • Tamás MJ, Karlgren S, Bill RM et al (2003) A short regulatory domain restricts glycerol transport through yeast Fps1p. J Biol Chem 278: 6337-6345.
    • (2003) J Biol Chem , vol.278 , pp. 6337-6345
    • Tamás, M.J.1    Karlgren, S.2    Bill, R.M.3
  • 249
    • 42949156828 scopus 로고    scopus 로고
    • A systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response
    • Tan K, Feizi H, Luo C, Fan SH, Ravasi T & Ideker TG. (2008) A systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response. P Natl Acad Sci USA 105: 2934-2939.
    • (2008) P Natl Acad Sci USA , vol.105 , pp. 2934-2939
    • Tan, K.1    Feizi, H.2    Luo, C.3    Fan, S.H.4    Ravasi, T.5    Ideker, T.G.6
  • 250
    • 0022633689 scopus 로고
    • Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene
    • Thiele DJ & Hamer DH. (1986) Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene. Mol Cell Biol 6: 1158-1163.
    • (1986) Mol Cell Biol , vol.6 , pp. 1158-1163
    • Thiele, D.J.1    Hamer, D.H.2
  • 251
    • 0031457095 scopus 로고    scopus 로고
    • Metabolism of sulfur amino acids in Saccharomyces cerevisiae
    • Thomas D & Surdin-Kerjan Y. (1997)Metabolism of sulfur amino acids in Saccharomyces cerevisiae. Microbiol Mol Biol R 61: 503-532.
    • (1997) Microbiol Mol Biol R , vol.61 , pp. 503-532
    • Thomas, D.1    Surdin-Kerjan, Y.2
  • 252
    • 0037993828 scopus 로고    scopus 로고
    • Boon and bane of metal ions in medicine
    • Thompson KH & Orvig C. (2003) Boon and bane of metal ions in medicine. Science 300: 936-939.
    • (2003) Science , vol.300 , pp. 936-939
    • Thompson, K.H.1    Orvig, C.2
  • 253
    • 2342487990 scopus 로고    scopus 로고
    • Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes
    • Thorpe GW, Fong CS, Alic N, Higgins VJ & Dawes IW. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. P Natl Acad Sci USA 101: 6564-6569.
    • (2004) P Natl Acad Sci USA , vol.101 , pp. 6564-6569
    • Thorpe, G.W.1    Fong, C.S.2    Alic, N.3    Higgins, V.J.4    Dawes, I.W.5
  • 254
    • 33749500678 scopus 로고    scopus 로고
    • The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast
    • Thorsen M, Di Y, Tangemo C et al (2006) The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast. Mol Biol Cell 17: 4400-4410.
    • (2006) Mol Biol Cell , vol.17 , pp. 4400-4410
    • Thorsen, M.1    Di, Y.2    Tangemo, C.3
  • 255
    • 34447279050 scopus 로고    scopus 로고
    • Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite
    • Thorsen M, Lagniel G, Kristiansson E, Junot C, Nerman O, Labarre J & Tamás MJ. (2007) Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite. Physiol Genomics 30: 35-43.
    • (2007) Physiol Genomics , vol.30 , pp. 35-43
    • Thorsen, M.1    Lagniel, G.2    Kristiansson, E.3    Junot, C.4    Nerman, O.5    Labarre, J.6    Tamás, M.J.7
  • 256
    • 63049131900 scopus 로고    scopus 로고
    • Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae
    • Thorsen M, Perrone GG, Kristiansson E et al (2009) Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae. BMC Genomics 10: 105.
    • (2009) BMC Genomics , vol.10 , pp. 105
    • Thorsen, M.1    Perrone, G.G.2    Kristiansson, E.3
  • 257
    • 0025136234 scopus 로고
    • Resistance to cadmium is under control of the CAD2 gene in the yeast Saccharomyces cerevisiae
    • Tohoyama H, Inouhe M, Joho M & Murayama T. (1990) Resistance to cadmium is under control of the CAD2 gene in the yeast Saccharomyces cerevisiae. Curr Genet 18: 181-185.
    • (1990) Curr Genet , vol.18 , pp. 181-185
    • Tohoyama, H.1    Inouhe, M.2    Joho, M.3    Murayama, T.4
  • 258
    • 0032523783 scopus 로고    scopus 로고
    • Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1
    • Toone WM, Kuge S, Samuels M, Morgan BA, Toda T & Jones N. (1998) Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Gene Dev 12: 1453-1463.
    • (1998) Gene Dev , vol.12 , pp. 1453-1463
    • Toone, W.M.1    Kuge, S.2    Samuels, M.3    Morgan, B.A.4    Toda, T.5    Jones, N.6
  • 259
    • 0035971410 scopus 로고    scopus 로고
    • Redox control of AP-1-like factors in yeast and beyond
    • Toone WM,Morgan BA & Jones N. (2001) Redox control of AP-1-like factors in yeast and beyond. Oncogene 20: 2336-2346.
    • (2001) Oncogene , vol.20 , pp. 2336-2346
    • Toone, W.M.1    Morgan, B.A.2    Jones, N.3
  • 260
    • 0031735176 scopus 로고    scopus 로고
    • Selenium metabolism in Escherichia coli
    • Turner RJ, Weiner JH & Taylor DE. (1998) Selenium metabolism in Escherichia coli. Biometals 11: 223-227.
    • (1998) Biometals , vol.11 , pp. 223-227
    • Turner, R.J.1    Weiner, J.H.2    Taylor, D.E.3
  • 261
    • 34249813098 scopus 로고    scopus 로고
    • Sch9 is a major target of TORC1 in Saccharomyces cerevisiae
    • Urban J, Soulard A, Huber A et al (2007) Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Mol Cell 26: 663-674.
    • (2007) Mol Cell , vol.26 , pp. 663-674
    • Urban, J.1    Soulard, A.2    Huber, A.3
  • 262
    • 0034613243 scopus 로고    scopus 로고
    • Mechanism of heavy metal ion activation of phytochelatin (PC) synthase: blocked thiols are sufficient for PC synthase-catalyzed transpeptidation of glutathione and related thiol peptides
    • Vatamaniuk OK, Mari S, Lu YP & Rea PA. (2000) Mechanism of heavy metal ion activation of phytochelatin (PC) synthase: blocked thiols are sufficient for PC synthase-catalyzed transpeptidation of glutathione and related thiol peptides. J Biol Chem 275: 31451-31459.
    • (2000) J Biol Chem , vol.275 , pp. 31451-31459
    • Vatamaniuk, O.K.1    Mari, S.2    Lu, Y.P.3    Rea, P.A.4
  • 263
    • 0042733228 scopus 로고    scopus 로고
    • Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor
    • Veal EA, Ross SJ, Malakasi P, Peacock E & Morgan BA. (2003) Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor. J Biol Chem 278: 30896-30904.
    • (2003) J Biol Chem , vol.278 , pp. 30896-30904
    • Veal, E.A.1    Ross, S.J.2    Malakasi, P.3    Peacock, E.4    Morgan, B.A.5
  • 264
    • 0037160016 scopus 로고    scopus 로고
    • Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide
    • Verma A, Mohindru M, Deb DK et al (2002) Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide. J Biol Chem 277: 44988-44995.
    • (2002) J Biol Chem , vol.277 , pp. 44988-44995
    • Verma, A.1    Mohindru, M.2    Deb, D.K.3
  • 266
    • 2942538583 scopus 로고    scopus 로고
    • Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration
    • Vivancos AP, Castillo EA, Jones N, Ayte J & Hidalgo E. (2004) Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration. Mol Microbiol 52: 1427-1435.
    • (2004) Mol Microbiol , vol.52 , pp. 1427-1435
    • Vivancos, A.P.1    Castillo, E.A.2    Jones, N.3    Ayte, J.4    Hidalgo, E.5
  • 269
    • 0037072773 scopus 로고    scopus 로고
    • Combinatorial control of yeast FET4 gene expression by iron, zinc, and oxygen
    • Waters BM & Eide DJ. (2002) Combinatorial control of yeast FET4 gene expression by iron, zinc, and oxygen. J Biol Chem 277: 33749-33757.
    • (2002) J Biol Chem , vol.277 , pp. 33749-33757
    • Waters, B.M.1    Eide, D.J.2
  • 270
    • 0028575444 scopus 로고
    • Cadmium tolerance mediated by the yeast AP-1 protein requires the presence of an ATP-binding cassette transporterencoding gene, YCF1
    • Wemmie JA, Szczypka MS, Thiele DJ & Moye-Rowley WS. (1994) Cadmium tolerance mediated by the yeast AP-1 protein requires the presence of an ATP-binding cassette transporterencoding gene, YCF1. J Biol Chem 269: 32592-32597.
    • (1994) J Biol Chem , vol.269 , pp. 32592-32597
    • Wemmie, J.A.1    Szczypka, M.S.2    Thiele, D.J.3    Moye-Rowley, W.S.4
  • 271
    • 37249084060 scopus 로고    scopus 로고
    • P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells
    • Wen J, Cheng HY, Feng Y et al (2008) P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells. Brit J Haematol 140: 169-180.
    • (2008) Brit J Haematol , vol.140 , pp. 169-180
    • Wen, J.1    Cheng, H.Y.2    Feng, Y.3
  • 272
    • 0030783122 scopus 로고    scopus 로고
    • Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3
    • Wendler F, Bergler H, Prutej K, Jungwirth H, Zisser G, Kuchler K & Hogenauer G. (1997) Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3. J Biol Chem 272: 27091-27098.
    • (1997) J Biol Chem , vol.272 , pp. 27091-27098
    • Wendler, F.1    Bergler, H.2    Prutej, K.3    Jungwirth, H.4    Zisser, G.5    Kuchler, K.6    Hogenauer, G.7
  • 273
    • 0036187717 scopus 로고    scopus 로고
    • The adaptive response of Saccharomyces cerevisiae to mercury exposure
    • Westwater J,McLaren NF, Dormer UH & Jamieson DJ. (2002) The adaptive response of Saccharomyces cerevisiae to mercury exposure. Yeast 19: 233-239.
    • (2002) Yeast , vol.19 , pp. 233-239
    • Westwater, J.1    McLaren, N.F.2    Dormer, U.H.3    Jamieson, D.J.4
  • 274
    • 0346749524 scopus 로고    scopus 로고
    • Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors
    • Wheeler GL, Trotter EW, Dawes IW & Grant CM. (2003) Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors. J Biol Chem 278: 49920-49928.
    • (2003) J Biol Chem , vol.278 , pp. 49920-49928
    • Wheeler, G.L.1    Trotter, E.W.2    Dawes, I.W.3    Grant, C.M.4
  • 275
    • 0022432526 scopus 로고
    • Yeast metallothionein Sequence and metal-binding properties
    • Winge DR, Nielson KB, Gray WR & Hamer DH. (1985) Yeast metallothionein. Sequence and metal-binding properties. J Biol Chem 260: 14464-14470.
    • (1985) J Biol Chem , vol.260 , pp. 14464-14470
    • Winge, D.R.1    Nielson, K.B.2    Gray, W.R.3    Hamer, D.H.4
  • 276
    • 0142103880 scopus 로고    scopus 로고
    • The redox domain of the Yap1p transcription factor contains two disulfide bonds
    • Wood MJ, Andrade EC & Storz G. (2003) The redox domain of the Yap1p transcription factor contains two disulfide bonds. Biochemistry 42: 11982-11991.
    • (2003) Biochemistry , vol.42 , pp. 11982-11991
    • Wood, M.J.1    Andrade, E.C.2    Storz, G.3
  • 277
    • 4344562921 scopus 로고    scopus 로고
    • Structural basis for redox regulation of Yap1 transcription factor localization
    • Wood MJ, Storz G & Tjandra N. (2004) Structural basis for redox regulation of Yap1 transcription factor localization. Nature 430: 917-921.
    • (2004) Nature , vol.430 , pp. 917-921
    • Wood, M.J.1    Storz, G.2    Tjandra, N.3
  • 278
    • 0028168801 scopus 로고
    • GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation
    • Wu AL & Moye-Rowley WS. (1994) GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. Mol Cell Biol 14: 5832-5839.
    • (1994) Mol Cell Biol , vol.14 , pp. 5832-5839
    • Wu, A.L.1    Moye-Rowley, W.S.2
  • 279
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, Loewith R & Hall MN. (2006) TOR signaling in growth and metabolism. Cell 124: 471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 280
    • 34047142681 scopus 로고    scopus 로고
    • Phytochelatins are synthesized by two vacuolar serine carboxypeptidases in Saccharomyces cerevisiae
    • Wünschmann J, Beck A, Meyer L, Letzel T, Grill E & Lendzian KJ. (2007) Phytochelatins are synthesized by two vacuolar serine carboxypeptidases in Saccharomyces cerevisiae. FEBS Lett 581: 1681-1687.
    • (2007) FEBS Lett , vol.581 , pp. 1681-1687
    • Wünschmann, J.1    Beck, A.2    Meyer, L.3    Letzel, T.4    Grill, E.5    Lendzian, K.J.6
  • 281
    • 0035692234 scopus 로고    scopus 로고
    • Phosphate transport and sensing in Saccharomyces cerevisiae
    • Wykoff DD & O'Shea EK. (2001) Phosphate transport and sensing in Saccharomyces cerevisiae. Genetics 159: 1491-1499.
    • (2001) Genetics , vol.159 , pp. 1491-1499
    • Wykoff, D.D.1    O'Shea, E.K.2
  • 282
    • 0030728763 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae ACR3 gene encodes a putative membrane protein involved in arsenite transport
    • Wysocki R, Bobrowicz P & Ulaszewski S. (1997) The Saccharomyces cerevisiae ACR3 gene encodes a putative membrane protein involved in arsenite transport. J Biol Chem 272: 30061-30066.
    • (1997) J Biol Chem , vol.272 , pp. 30061-30066
    • Wysocki, R.1    Bobrowicz, P.2    Ulaszewski, S.3
  • 285
    • 2342479179 scopus 로고    scopus 로고
    • Transcriptional activation of metalloid tolerance genes in Saccharomyces cerevisiae requires the AP-1-like proteins Yap1p and Yap8p
    • Wysocki R, Fortier PK, Maciaszczyk E et al (2004) Transcriptional activation of metalloid tolerance genes in Saccharomyces cerevisiae requires the AP-1-like proteins Yap1p and Yap8p. Mol Biol Cell 15: 2049-2060.
    • (2004) Mol Biol Cell , vol.15 , pp. 2049-2060
    • Wysocki, R.1    Fortier, P.K.2    Maciaszczyk, E.3
  • 287
    • 0032535486 scopus 로고    scopus 로고
    • Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor
    • Yan C, Lee LH & Davis LI. (1998) Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor. EMBO J 17: 7416-7429.
    • (1998) EMBO J , vol.17 , pp. 7416-7429
    • Yan, C.1    Lee, L.H.2    Davis, L.I.3
  • 288
    • 26444519913 scopus 로고    scopus 로고
    • Novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti
    • Yang HC, Cheng J, Finan TM, Rosen BP & Bhattacharjee H. (2005) Novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti. J Bacteriol 187: 6991-6997.
    • (2005) J Bacteriol , vol.187 , pp. 6991-6997
    • Yang, H.C.1    Cheng, J.2    Finan, T.M.3    Rosen, B.P.4    Bhattacharjee, H.5
  • 290
    • 0029975206 scopus 로고    scopus 로고
    • A putative new membrane protein, Pho86p, in the inorganic phosphate uptake system of Saccharomyces cerevisiae
    • Yompakdee C, Bun-ya M, Shikata K, Ogawa N, Harashima S & Oshima Y. (1996a) A putative new membrane protein, Pho86p, in the inorganic phosphate uptake system of Saccharomyces cerevisiae. Gene 171: 41-47.
    • (1996) Gene , vol.171 , pp. 41-47
    • Yompakdee, C.1    Bun-ya, M.2    Shikata, K.3    Ogawa, N.4    Harashima, S.5    Oshima, Y.6
  • 291
    • 0030054432 scopus 로고    scopus 로고
    • A putative membrane protein, Pho88p, involved in inorganic phosphate transport in Saccharomyces cerevisiae
    • Yompakdee C, Ogawa N, Harashima S & Oshima Y. (1996b) A putative membrane protein, Pho88p, involved in inorganic phosphate transport in Saccharomyces cerevisiae. Mol Gen Genet 251: 580-590.
    • (1996) Mol Gen Genet , vol.251 , pp. 580-590
    • Yompakdee, C.1    Ogawa, N.2    Harashima, S.3    Oshima, Y.4
  • 292
    • 34547650774 scopus 로고    scopus 로고
    • Identification of arsenic-binding proteins in human breast cancer cells
    • Zhang X, Yang F, Shim JY, Kirk KL, Anderson DE & Chen X. (2007) Identification of arsenic-binding proteins in human breast cancer cells. Cancer Lett 255: 95-106.
    • (2007) Cancer Lett , vol.255 , pp. 95-106
    • Zhang, X.1    Yang, F.2    Shim, J.Y.3    Kirk, K.L.4    Anderson, D.E.5    Chen, X.6
  • 293
    • 0029911793 scopus 로고    scopus 로고
    • The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation
    • Zhao H & Eide D. (1996) The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. P Natl Acad Sci USA 93: 2454-2458.
    • (1996) P Natl Acad Sci USA , vol.93 , pp. 2454-2458
    • Zhao, H.1    Eide, D.2
  • 294
    • 33745400573 scopus 로고    scopus 로고
    • Bifunctional role of the leishmanial antimonate reductase LmACR2 as a protein tyrosine phosphatase
    • Zhou Y, Bhattacharjee H &Mukhopadhyay R. (2006) Bifunctional role of the leishmanial antimonate reductase LmACR2 as a protein tyrosine phosphatase. Mol Biochem Parasit 148: 161-168.
    • (2006) Mol Biochem Parasit , vol.148 , pp. 161-168
    • Zhou, Y.1    Bhattacharjee, H.2    Mukhopadhyay, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.