Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide

Journal of Biological Chemistry

Volumn 277, Issue 47, 2002, Pages 44988-44995

  Verma, Amit ^a,b   Mohindru, Mani ^a   Deb, Dilip K ^b   Sassano, Antonella ^a,b   Kambhampati, Suman ^a,b   Ravandi, Farhad ^b   Minucci, Saverio ^c   Kalvakolanul, Dhananjaya V ^d   Platanias, Leonidas C ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC COMPOUNDS; BONE; CELLS;

PHARMACOLOGICAL INHIBITION;

ENZYMES;

ARSENIC TRIOXIDE; ASCORBIC ACID; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RAC1 PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BONE MARROW CELL; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; COLONY FORMING UNIT GM; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; GENE ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TARGET CELL;

ANTIOXIDANTS; APOPTOSIS; ARSENICALS; ASCORBIC ACID; BONE MARROW CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; GROWTH INHIBITORS; HUMANS; IMIDAZOLES; ISOENZYMES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RAC1 GTP-BINDING PROTEIN; TUMOR CELLS, CULTURED;

CUCURBITA;

EID: 0037160016     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207176200     Document Type: Article

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