Zinc finger proteins as potential targets for toxic metal ions: Differential effects on structure and function

Antioxidants and Redox Signaling

Volumn 3, Issue 4, 2001, Pages 625-634

  Hartwig, A ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; COBALT; CYSTEINE; DNA; HISTIDINE; METAL ION; NICKEL; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

DNA REPAIR; DNA TRANSCRIPTION; GENE EXPRESSION; GROWTH REGULATION; HUMAN; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; REVIEW;

EID: 0034871083     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/15230860152542970     Document Type: Review

References (57)

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11. 15N-NMR spectroscopic studies on the zinc(II)- and cadmium(II)-associated minimal DNA-binding domain (M98-F219)
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13. Spectroscopic characterization of Co(II)-, Ni(II)-, and Cd(II)-substituted wild-type and non-native retroviral-type zinc finger peptides
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28. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA
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32. Ligand variation and metal ion binding specificity in zinc finger peptides
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34. Human xeroderma pigmentosum group A protein interacts with human replication protein A and inhibits DNA replication
35. Zinc fingers are sticking together
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37. The interactions of zinc, nickel, and cadmium with Xenopus transcription factor IIIA, assessed by equilibrium dialysis
38. Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells
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40. Mutational analysis of the structure and function of the xeroderma pigmentosum group A complementing protein. Identification of essential domains for nuclear localization and DNA excision repair
41. Alteration of DNA binding specificity by nickel (II) substitution in three zinc (II) fingers of transcription factor Sp1
42. Evidence from extended x-ray absorption fine structure and site-specific mutagenesis for zinc fingers in UvrA protein of Escherichia coli
43. FPG protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role
44. Zinc finger of replication protein A, a non-DNA binding element, regulates its DNA binding activity through redox
45. Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome
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48. Complementation of DNA repair in xeroderma pigmentosum group A cell extracts by a protein with affinity for damaged DNA
49. Sequential metal binding by the RING finger domain of BRCA1
50. Modulation of DNA binding of a tramtrack zinc finger peptide by the metallothionein-thionein conjugate pair
51. Metal replacement in DNA-binding zinc finger proteins and its relevance to mutagenicity and carcinogenicity through free radical generation
52. Finger-loops, oncogenes, and metals. Claude Passmore Brown Memorial Lecture
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54. 8-Oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity
55. Transition metals modulate DNA-protein interactions of SP1 zinc finger domains with its cognate target site
56. Physical and functional sensitivity of zinc finger transcription factors to redox change
57. Inhibition of poly(ADP-ribose) polymerase by arsenite