A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation

Cell

Volumn 111, Issue 4, 2002, Pages 471-481

  Delaunay, Agnès ^a   Pflieger, Delphine ^b   Barrault, Marie Bénédicte ^a   Vinh, Joelle ^b   Toledano, Michel B ^a  

^a CEA SACLAY   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; RECEPTOR; THIOL DERIVATIVE; THIOREDOXIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG; CYSTEINE; DISULFIDE; DNA BINDING PROTEIN; FUNGAL DNA; FUNGAL PROTEIN; GLUTATHIONE; HYBRID PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; YAP1 PROTEIN, S CEREVISIAE;

ARTICLE; DISULFIDE BOND; ENZYME ACTIVE SITE; EUKARYOTE; GENE ACTIVATION; MOLECULAR DYNAMICS; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

BASE SEQUENCE; CYSTEINE; DISULFIDES; DNA, FUNGAL; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; THIOREDOXIN; TRANSCRIPTION FACTORS;

EID: 0037110454     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)01048-6     Document Type: Article

References (32)

1. Avery A.M., Avery S.V. Saccharomyces cerevisiae expresses three phospholipid hydroperoxide glutathione peroxidases. J. Biol. Chem. 276:2001;33730-33735.
2. Bjornstedt M., Xue J., Huang W., Akesson B., Holmgren A. The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase. J. Biol. Chem. 269:1994;29382-29384.
3. Brigelius-Flohe R. Tissue-specific functions of individual glutathione peroxidases. Free Radic. Biol. Med. 27:1999;951-965.
4. Carmel-Harel O., Stearman R., Gasch A.P., Botstein D., Brown P.O., Storz G. Role of thioredoxin reductase in the Yap1p-dependent response to oxidative stress in Saccharomyces cerevisiae. Mol. Microbiol. 39:2001;595-605.
5. Chae H.Z., Chung S.J., Rhee S.G. Thioredoxin-dependent peroxide reductase from yeast. J. Biol. Chem. 269:1994;27670-27678.
6. Claiborne A., Yeh J.I., Mallett T.C., Luba J., Crane E.J., Charrier V., Parsonage D. Protein-sulfenic acids. diverse roles for an unlikely player in enzyme catalysis and redox regulation Biochemistry. 38:1999;15407-15416.
7. Coleman S.T., Epping E.A., Steggerda S.M., Moye-Rowley W.S. Yap1p activates gene transcription in an oxidant-specific fashion. Mol. Cell. Biol. 19:1999;8302-8313.
8. 2 sensing through oxidation of the Yap1 transcription factor. EMBO J. 19:2000;5157-5166.
9. Ellis H.R., Poole L.B. Roles for the two cysteine residues of AhpC in catalysis of peroxide reduction by alkyl hydroperoxide reductase from Salmonella typhimurium. Biochemistry. 36:1997;13349-13356.
10. Gasch A.P., Spellman P.T., Kao C.M., Carmel-Harel O., Eisen M.B., Storz G., Botstein D., Brown P.O. Genomic expression programs in the response of yeast cells to environmental changes. Mol. Biol. Cell. 11:2000;4241-4257.
11. Godeas C., Tramer F., Micali F., Soranzo M., Sandri G., Panfili E. Distribution and possible novel role of phospholipid hydroperoxide glutathione peroxidase in rat epididymal spermatozoa. Biol. Reprod. 57:1997;1502-1508.
12. Gonzalez-Flecha B., Demple B. Genetic responses to free radicals. Homeostasis and gene control. Ann. N Y Acad. Sci. 899:2000;69-87.
13. Inoue Y., Matsuda T., Sugiyama S., Izawa S., Kimura A. Genetic analysis of glutathione peroxidase in oxidative stress response of Saccharomyces cerevisiae. J. Biol. Chem. 274:1999;27002-27009.
14. Izawa S., Maeda K., Sugiyama K., Mano J., Inoue Y., Kimura A. Thioredoxin deficiency causes the constitutive activation of Yap1, an AP-1-like transcription factor in Saccharomyces cerevisiae. J. Biol. Chem. 274:1999;28459-28465.
15. Kim S.O., Merchant K., Nudelman R., Beyer W.F. Jr., Keng T., DeAngelo J., Hausladen A., Stamler J.S. OxyR. a molecular code for redox-related signaling Cell. 109:2002;383-396.
16. Kuge S., Jones N. YAP1 dependent activation fo TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides. EMBO J. 13:1994;655-664.
17. Kuge S., Jones N., Nomoto A. Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J. 16:1997;1710-1720.
18. Kuge S., Toda T., Lizuka N., Nomoto A. Crm1 (Xpo1) dependent nuclear export of the budding yeast transcription factor yAP-1 is sensitive to oxidative stress. Genes Cells. 3:1998;521-532.
19. Kuge S., Arita M., Murayama A., Maeta K., Izawa S., Inoue Y., Nomoto A. Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation. Mol. Cell. Biol. 21:2001;6139-6150.
20. Lee J., Godon C., Lagniel G., Spector D., Garin J., Labarre J., Toledano M.B. Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J. Biol. Chem. 274:1999;16040-16046.
21. Maiorino M., Flohe L., Roveri A., Steinert P., Wissing J.B., Ursini F. Selenium and reproduction. Biofactors. 10:1999;251-256.
22. Pomposiello P.J., Demple B. Redox-operated genetic switches. the SoxR and OxyR transcription factors Trends Biotechnol. 19:2001;109-114.
23. Shevchenko A., Wilm M., Vorm O., Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68:1996;850-858.
24. Sikorski R.S., Hieter P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:1989;19-27.
25. Spector D., Labarre J., Toledano M.B. A genetic investigation of the essential role of glutathione. mutations in the proline biosynthesis pathway are the only suppressors of glutathione auxotrophy in yeast J. Biol. Chem. 276:2000;7011-7016.
26. Ursini F., Heim S., Kiess M., Maiorino M., Roveri A., Wissing J., Flohe L. Dual function of the selenoprotein PHGPx during sperm maturation. Science. 285:1999;1393-1396.
27. Ursini F., Maiorino M., Brigelius-Flohe R., Aumann K.D., Roveri A., Schomburg D., Flohe L. Diversity of glutathione peroxidases. Methods Enzymol. 252:1995;38-53.
28. Ursini F., Maiorino M., Roveri A. Phospholipid hydroperoxide glutathione peroxidase (PHGPx). more than an antioxidant enzyme? Biomed. Environ. Sci. 10:1997;327-332.
29. Vido K., Spector D., Lagniel G., Lopez S., Toledano M.B., Labarre J. A proteome analysis of the cadmium response in Saccharomyces cerevisiae. J. Biol. Chem. 276:2000;8469-8474.
30. Wu A., Wemmie J.A., Nicholas P., Edgington N.P., Goebl M., Guevara J.L., Moye-Rowley W.S. Yeast bZip proteins mediate pleiotropic drug and metal resistance. J. Biol. Chem. 268:1993;18850-18858.
31. Yan C., Lee L.H., Davis L.I. Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor. EMBO J. 17:1998;7416-7429.
32. Zheng M., Aslund F., Storz G. Activation of the OxyR transcription factor by reversible disulfide bond formation. Science. 279:1998;1718-1721.