-
1
-
-
0033609012
-
Pathways of As(III) detoxification in Saccharomyces cerevisiae
-
Ghosh M., Shen J., and Rosen B.P. Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 5001-5006
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 5001-5006
-
-
Ghosh, M.1
Shen, J.2
Rosen, B.P.3
-
2
-
-
2442605626
-
As(III) and Sb(III) uptake by GlpF and efflux by ArsB in Escherichia coli
-
Meng Y.L., Liu Z., and Rosen B.P. As(III) and Sb(III) uptake by GlpF and efflux by ArsB in Escherichia coli. J. Biol. Chem. 279 (2004) 18334-18341
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18334-18341
-
-
Meng, Y.L.1
Liu, Z.2
Rosen, B.P.3
-
3
-
-
0031896498
-
The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite
-
Sato T., and Kobayashi Y. The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite. J. Bacteriol. 180 (1998) 1655-1661
-
(1998)
J. Bacteriol.
, vol.180
, pp. 1655-1661
-
-
Sato, T.1
Kobayashi, Y.2
-
4
-
-
26444519913
-
Novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti
-
Yang H.C., Cheng J., Finan T.M., Rosen B.P., and Bhattacharjee H. Novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti. J. Bacteriol. 187 (2005) 6991-6997
-
(2005)
J. Bacteriol.
, vol.187
, pp. 6991-6997
-
-
Yang, H.C.1
Cheng, J.2
Finan, T.M.3
Rosen, B.P.4
Bhattacharjee, H.5
-
5
-
-
0025186765
-
Molecular characterization of an anion pump. The ArsB protein is the membrane anchor for the ArsA protein
-
Tisa L.S., and Rosen B.P. Molecular characterization of an anion pump. The ArsB protein is the membrane anchor for the ArsA protein. J. Biol. Chem. 265 (1990) 190-194
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 190-194
-
-
Tisa, L.S.1
Rosen, B.P.2
-
6
-
-
0028796058
-
Dual mode of energy coupling by the oxyanion-translocating ArsB protein
-
Dey S., and Rosen B.P. Dual mode of energy coupling by the oxyanion-translocating ArsB protein. J. Bacteriol. 177 (1995) 385-389
-
(1995)
J. Bacteriol.
, vol.177
, pp. 385-389
-
-
Dey, S.1
Rosen, B.P.2
-
7
-
-
4444328639
-
Lactose permease as a paradigm for membrane transport proteins (Review)
-
Abramson J., Iwata S., and Kaback H.R. Lactose permease as a paradigm for membrane transport proteins (Review). Mol. Membr. Biol. 21 (2004) 227-236
-
(2004)
Mol. Membr. Biol.
, vol.21
, pp. 227-236
-
-
Abramson, J.1
Iwata, S.2
Kaback, H.R.3
-
8
-
-
0026622930
-
Membrane topology of the ArsB protein, the membrane subunit of an anion-translocating ATPase
-
Wu J., Tisa L.S., and Rosen B.P. Membrane topology of the ArsB protein, the membrane subunit of an anion-translocating ATPase. J. Biol. Chem. 267 (1992) 12570-12576
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12570-12576
-
-
Wu, J.1
Tisa, L.S.2
Rosen, B.P.3
-
9
-
-
40949085182
-
Diversity of arsenite transporter genes from arsenic-resistant soil bacteria
-
Achour A.R., Bauda P., and Billard P. Diversity of arsenite transporter genes from arsenic-resistant soil bacteria. Res. Microbiol. (2006)
-
(2006)
Res. Microbiol.
-
-
Achour, A.R.1
Bauda, P.2
Billard, P.3
-
10
-
-
0037022611
-
Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis
-
Drew D., Sjöstrand D., Nilsson J., Urbig T., Chin C.N., de Gier J.W., and von Heijne G. Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 2690-2695
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 2690-2695
-
-
Drew, D.1
Sjöstrand, D.2
Nilsson, J.3
Urbig, T.4
Chin, C.N.5
de Gier, J.W.6
von Heijne, G.7
-
13
-
-
0025002908
-
Bacillus subtilis holo-cytochrome c-550 can be synthesised in aerobic Escherichia coli
-
von Wachenfeldt C., and Hederstedt L. Bacillus subtilis holo-cytochrome c-550 can be synthesised in aerobic Escherichia coli. FEBS Lett. 270 (1990) 147-151
-
(1990)
FEBS Lett.
, vol.270
, pp. 147-151
-
-
von Wachenfeldt, C.1
Hederstedt, L.2
-
14
-
-
1842611517
-
Experimentally based topology models for E. coli inner membrane proteins
-
Rapp M., Drew D., Daley D.O., Nilsson J., Carvalho T., Melen K., De Gier J.W., and Von Heijne G. Experimentally based topology models for E. coli inner membrane proteins. Protein Sci. 13 (2004) 937-945
-
(2004)
Protein Sci.
, vol.13
, pp. 937-945
-
-
Rapp, M.1
Drew, D.2
Daley, D.O.3
Nilsson, J.4
Carvalho, T.5
Melen, K.6
De Gier, J.W.7
Von Heijne, G.8
-
15
-
-
33748783370
-
Compact archaeal variant of heme A synthase
-
Lewin A., and Hederstedt L. Compact archaeal variant of heme A synthase. FEBS Lett. 580 (2006) 5351-5356
-
(2006)
FEBS Lett.
, vol.580
, pp. 5351-5356
-
-
Lewin, A.1
Hederstedt, L.2
-
16
-
-
0023472472
-
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
-
Schägger H., and von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166 (1987) 368-379
-
(1987)
Anal. Biochem.
, vol.166
, pp. 368-379
-
-
Schägger, H.1
von Jagow, G.2
-
17
-
-
1242273761
-
CtaG is required for formation of active cytochrome c oxidase in Bacillus subtilis
-
Bengtsson J., von Wachenfeldt C., Winstedt L., Nygaard P., and Hederstedt L. CtaG is required for formation of active cytochrome c oxidase in Bacillus subtilis. Microbiology 150 (2004) 415-425
-
(2004)
Microbiology
, vol.150
, pp. 415-425
-
-
Bengtsson, J.1
von Wachenfeldt, C.2
Winstedt, L.3
Nygaard, P.4
Hederstedt, L.5
-
18
-
-
0030759333
-
Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method
-
Cserzo M., Wallin E., Simon I., von Heijne G., and Elofsson A. Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Eng. 10 (1997) 673-676
-
(1997)
Protein Eng.
, vol.10
, pp. 673-676
-
-
Cserzo, M.1
Wallin, E.2
Simon, I.3
von Heijne, G.4
Elofsson, A.5
-
19
-
-
0032561132
-
Principles governing amino acid composition of integral membrane proteins: application to topology prediction
-
Tusnady G.E., and Simon I. Principles governing amino acid composition of integral membrane proteins: application to topology prediction. J. Mol. Biol. 283 (1998) 489-506
-
(1998)
J. Mol. Biol.
, vol.283
, pp. 489-506
-
-
Tusnady, G.E.1
Simon, I.2
-
20
-
-
0028211273
-
A model recognition approach to the prediction of all-helical membrane protein structure and topology
-
Jones D.T., Taylor W.R., and Thornton J.M. A model recognition approach to the prediction of all-helical membrane protein structure and topology. Biochemistry 33 (1994) 3038-3049
-
(1994)
Biochemistry
, vol.33
, pp. 3038-3049
-
-
Jones, D.T.1
Taylor, W.R.2
Thornton, J.M.3
-
21
-
-
0030038634
-
Topology prediction for helical transmembrane proteins at 86% accuracy
-
Rost B., Fariselli P., and Casadio R. Topology prediction for helical transmembrane proteins at 86% accuracy. Protein Sci. 5 (1996) 1704-1718
-
(1996)
Protein Sci.
, vol.5
, pp. 1704-1718
-
-
Rost, B.1
Fariselli, P.2
Casadio, R.3
-
22
-
-
0031826040
-
SOSUI: classification and secondary structure prediction system for membrane proteins
-
Hirokawa T., Boon-Chieng S., and Mitaku S. SOSUI: classification and secondary structure prediction system for membrane proteins. Bioinformatics 14 (1998) 378-379
-
(1998)
Bioinformatics
, vol.14
, pp. 378-379
-
-
Hirokawa, T.1
Boon-Chieng, S.2
Mitaku, S.3
-
24
-
-
18744403991
-
An improved hidden Markov model for transmembrane protein detection and topology prediction and its applications to complete genomes
-
Kahsay R.Y., Gao G., and Liao L. An improved hidden Markov model for transmembrane protein detection and topology prediction and its applications to complete genomes. Bioinformatics 21 (2005) 1853-1858
-
(2005)
Bioinformatics
, vol.21
, pp. 1853-1858
-
-
Kahsay, R.Y.1
Gao, G.2
Liao, L.3
-
25
-
-
0000207681
-
TMbase - A database of membrane spanning proteins segments
-
Hofmann K., and Stoffel W. TMbase - A database of membrane spanning proteins segments. Biol. Chem. Hoppe-Seyler 374 (1993) 166
-
(1993)
Biol. Chem. Hoppe-Seyler
, vol.374
, pp. 166
-
-
Hofmann, K.1
Stoffel, W.2
-
26
-
-
0028568176
-
TopPred II: an improved software for membrane protein structure predictions
-
Claros M.G., and von Heijne G. TopPred II: an improved software for membrane protein structure predictions. Comput. Appl. Biosci. 10 (1994) 685-686
-
(1994)
Comput. Appl. Biosci.
, vol.10
, pp. 685-686
-
-
Claros, M.G.1
von Heijne, G.2
-
27
-
-
0344406716
-
Reliability measures for membrane protein topology prediction algorithms
-
Melen K., Krogh A., and von Heijne G. Reliability measures for membrane protein topology prediction algorithms. J. Mol. Biol. 327 (2003) 735-744
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 735-744
-
-
Melen, K.1
Krogh, A.2
von Heijne, G.3
-
28
-
-
33747871503
-
ZPRED: predicting the distance to the membrane center for residues in alpha-helical membrane proteins
-
Granseth E., Viklund H., and Elofsson A. ZPRED: predicting the distance to the membrane center for residues in alpha-helical membrane proteins. Bioinformatics 22 (2006) e191-e196
-
(2006)
Bioinformatics
, vol.22
-
-
Granseth, E.1
Viklund, H.2
Elofsson, A.3
-
29
-
-
3242810318
-
MEGA3: integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
-
Kumar S., Tamura K., and Nei M. MEGA3: integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform. 5 (2004) 150-163
-
(2004)
Brief Bioinform.
, vol.5
, pp. 150-163
-
-
Kumar, S.1
Tamura, K.2
Nei, M.3
-
30
-
-
0027456615
-
Folding and assembly of bacterial alkaline phosphatase in vitro and in vivo
-
Akiyama Y., and Ito K. Folding and assembly of bacterial alkaline phosphatase in vitro and in vivo. J. Biol. Chem. 268 (1993) 8146-8150
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8146-8150
-
-
Akiyama, Y.1
Ito, K.2
-
31
-
-
0025836761
-
Escherichia coli alkaline phosphatase fails to acquire disulfide bonds when retained in the cytoplasm
-
Derman A.I., and Beckwith J. Escherichia coli alkaline phosphatase fails to acquire disulfide bonds when retained in the cytoplasm. J. Bacteriol. 173 (1991) 7719-7722
-
(1991)
J. Bacteriol.
, vol.173
, pp. 7719-7722
-
-
Derman, A.I.1
Beckwith, J.2
-
32
-
-
0033917124
-
Green fluorescent protein functions as a reporter for protein localization in Escherichia coli
-
Feilmeier B.J., Iseminger G., Schroeder D., Webber H., and Phillips G.J. Green fluorescent protein functions as a reporter for protein localization in Escherichia coli. J. Bacteriol. 182 (2000) 4068-4076
-
(2000)
J. Bacteriol.
, vol.182
, pp. 4068-4076
-
-
Feilmeier, B.J.1
Iseminger, G.2
Schroeder, D.3
Webber, H.4
Phillips, G.J.5
-
33
-
-
33845468702
-
Membrane topology mapping of the Na+-pumping NADH: quinone oxidoreductase from Vibrio cholerae by PhoA-green fluorescent protein fusion analysis
-
Duffy E.B., and Barquera B. Membrane topology mapping of the Na+-pumping NADH: quinone oxidoreductase from Vibrio cholerae by PhoA-green fluorescent protein fusion analysis. J. Bacteriol. 188 (2006) 8343-8351
-
(2006)
J. Bacteriol.
, vol.188
, pp. 8343-8351
-
-
Duffy, E.B.1
Barquera, B.2
-
34
-
-
3042539851
-
Membrane topology of the DrrB protein of the doxorubicin transporter of Streptomyces peucetius
-
Gandlur S.M., Wei L., Levine J., Russell J., and Kaur P. Membrane topology of the DrrB protein of the doxorubicin transporter of Streptomyces peucetius. J. Biol. Chem. 279 (2004) 27799-27806
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27799-27806
-
-
Gandlur, S.M.1
Wei, L.2
Levine, J.3
Russell, J.4
Kaur, P.5
-
35
-
-
0026529067
-
Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli
-
Andersson H., Bakker E., and von Heijne G. Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli. J. Biol. Chem. 267 (1992) 1491-1495
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1491-1495
-
-
Andersson, H.1
Bakker, E.2
von Heijne, G.3
-
36
-
-
0037073711
-
Membrane topology of the acyl-lipid desaturase from Bacillus subtilis
-
Diaz A.R., Mansilla M.C., Vila A.J., and de Mendoza D. Membrane topology of the acyl-lipid desaturase from Bacillus subtilis. J. Biol. Chem. 277 (2002) 48099-48106
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48099-48106
-
-
Diaz, A.R.1
Mansilla, M.C.2
Vila, A.J.3
de Mendoza, D.4
-
37
-
-
0025306403
-
The use of gene fusions to determine the topology of all of the subunits of the cytochrome o terminal oxidase complex of Escherichia coli
-
Chepuri V., and Gennis R.B. The use of gene fusions to determine the topology of all of the subunits of the cytochrome o terminal oxidase complex of Escherichia coli. J. Biol. Chem. 265 (1990) 12978-12986
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 12978-12986
-
-
Chepuri, V.1
Gennis, R.B.2
-
38
-
-
0033569920
-
Transmembrane segment (TMS) VIII of the Na(+)/Citrate transporter CitS requires downstream TMS IX for insertion in the Escherichia coli membrane
-
van Geest M., and Lolkema J.S. Transmembrane segment (TMS) VIII of the Na(+)/Citrate transporter CitS requires downstream TMS IX for insertion in the Escherichia coli membrane. J. Biol. Chem. 274 (1999) 29705-29711
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29705-29711
-
-
van Geest, M.1
Lolkema, J.S.2
-
39
-
-
0025330038
-
Lac permease of Escherichia coli: topology and sequence elements promoting membrane insertion
-
Calamia J., and Manoil C. Lac permease of Escherichia coli: topology and sequence elements promoting membrane insertion. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 4937-4941
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 4937-4941
-
-
Calamia, J.1
Manoil, C.2
-
40
-
-
0041353145
-
Structure and mechanism of the lactose permease of Escherichia coli
-
Abramson J., Smirnova I., Kasho V., Verner G., Kaback H.R., and Iwata S. Structure and mechanism of the lactose permease of Escherichia coli. Science 301 (2003) 610-615
-
(2003)
Science
, vol.301
, pp. 610-615
-
-
Abramson, J.1
Smirnova, I.2
Kasho, V.3
Verner, G.4
Kaback, H.R.5
Iwata, S.6
-
41
-
-
0036891703
-
Prediction of partial membrane protein topologies using a consensus approach
-
Nilsson J., Persson B., and Von Heijne G. Prediction of partial membrane protein topologies using a consensus approach. Protein Sci. 11 (2002) 2974-2980
-
(2002)
Protein Sci.
, vol.11
, pp. 2974-2980
-
-
Nilsson, J.1
Persson, B.2
Von Heijne, G.3
-
42
-
-
0024442722
-
Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues
-
von Heijne G. Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues. Nature 341 (1989) 456-458
-
(1989)
Nature
, vol.341
, pp. 456-458
-
-
von Heijne, G.1
-
43
-
-
20444366208
-
Tilt angle of a trans-membrane helix is determined by hydrophobic mismatch
-
Park S.H., and Opella S.J. Tilt angle of a trans-membrane helix is determined by hydrophobic mismatch. J. Mol. Biol. 350 (2005) 310-318
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 310-318
-
-
Park, S.H.1
Opella, S.J.2
-
44
-
-
4444343863
-
Lipid bilayer topology of the transmembrane alpha-helix of M13 Major coat protein and bilayer polarity profile by site-directed fluorescence spectroscopy
-
Koehorst R.B., Spruijt R.B., Vergeldt F.J., and Hemminga M.A. Lipid bilayer topology of the transmembrane alpha-helix of M13 Major coat protein and bilayer polarity profile by site-directed fluorescence spectroscopy. Biophys. J. 87 (2004) 1445-1455
-
(2004)
Biophys. J.
, vol.87
, pp. 1445-1455
-
-
Koehorst, R.B.1
Spruijt, R.B.2
Vergeldt, F.J.3
Hemminga, M.A.4
-
45
-
-
0034705142
-
Internal packing of helical membrane proteins
-
Eilers M., Shekar S.C., Shieh T., Smith S.O., and Fleming P.J. Internal packing of helical membrane proteins. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 5796-5801
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5796-5801
-
-
Eilers, M.1
Shekar, S.C.2
Shieh, T.3
Smith, S.O.4
Fleming, P.J.5
-
46
-
-
0031398840
-
From membrane to molecule to the third amino acid from the left with a membrane transport protein
-
Kaback H.R., and Wu J. From membrane to molecule to the third amino acid from the left with a membrane transport protein. Q. Rev. Biophys. 30 (1997) 333-364
-
(1997)
Q. Rev. Biophys.
, vol.30
, pp. 333-364
-
-
Kaback, H.R.1
Wu, J.2
-
47
-
-
26844558809
-
Analysis of genes involved in arsenic resistance in Corynebacterium glutamicum ATCC 13032
-
Ordonez E., Letek M., Valbuena N., Gil J.A., and Mateos L.M. Analysis of genes involved in arsenic resistance in Corynebacterium glutamicum ATCC 13032. Appl. Environ. Microbiol. 71 (2005) 6206-6215
-
(2005)
Appl. Environ. Microbiol.
, vol.71
, pp. 6206-6215
-
-
Ordonez, E.1
Letek, M.2
Valbuena, N.3
Gil, J.A.4
Mateos, L.M.5
-
48
-
-
33646584815
-
arsRBOCT arsenic resistance system encoded by linear plasmid pHZ227 in Streptomyces sp. strain FR-008
-
Wang L., Chen S., Xiao X., Huang X., You D., Zhou X., and Deng Z. arsRBOCT arsenic resistance system encoded by linear plasmid pHZ227 in Streptomyces sp. strain FR-008. Appl. Environ. Microbiol. 72 (2006) 3738-3742
-
(2006)
Appl. Environ. Microbiol.
, vol.72
, pp. 3738-3742
-
-
Wang, L.1
Chen, S.2
Xiao, X.3
Huang, X.4
You, D.5
Zhou, X.6
Deng, Z.7
-
49
-
-
33846452511
-
The bile/arsenite/riboflavin transporter (BART) superfamily
-
Mansour N.M., Sawhney M., Tamang D.G., Vogl C., and Saier M.H. The bile/arsenite/riboflavin transporter (BART) superfamily. FEBS J. 274 (2007) 612-629
-
(2007)
FEBS J.
, vol.274
, pp. 612-629
-
-
Mansour, N.M.1
Sawhney, M.2
Tamang, D.G.3
Vogl, C.4
Saier, M.H.5
-
50
-
-
0033567092
-
Protein, lipid and water organization in bacteriorhodopsin crystals: a molecular view of the purple membrane at 1.9 Å resolution
-
Belrhali H., Nollert P., Royant A., Menzel C., Rosenbusch J.P., Landau E.M., and Pebay-Peyroula E. Protein, lipid and water organization in bacteriorhodopsin crystals: a molecular view of the purple membrane at 1.9 Å resolution. Structure 7 (1999) 909-917
-
(1999)
Structure
, vol.7
, pp. 909-917
-
-
Belrhali, H.1
Nollert, P.2
Royant, A.3
Menzel, C.4
Rosenbusch, J.P.5
Landau, E.M.6
Pebay-Peyroula, E.7
-
51
-
-
0742288411
-
The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors
-
Yohannan S., Faham S., Yang D., Whitelegge J.P., and Bowie J.U. The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 959-963
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 959-963
-
-
Yohannan, S.1
Faham, S.2
Yang, D.3
Whitelegge, J.P.4
Bowie, J.U.5
-
52
-
-
0035795161
-
Transmembrane orientation and topology of the NADH:quinone oxidoreductase putative quinone binding subunit NuoH
-
Roth R., and Hagerhall C. Transmembrane orientation and topology of the NADH:quinone oxidoreductase putative quinone binding subunit NuoH. Biochim. Biophys. Acta 1504 (2001) 352-362
-
(2001)
Biochim. Biophys. Acta
, vol.1504
, pp. 352-362
-
-
Roth, R.1
Hagerhall, C.2
-
53
-
-
0029973636
-
FACS-optimized mutants of the green fluorescent protein (GFP)
-
Cormack B.P., Valdivia R.H., and Falkow S. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173 (1996) 33-38
-
(1996)
Gene
, vol.173
, pp. 33-38
-
-
Cormack, B.P.1
Valdivia, R.H.2
Falkow, S.3
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