Cadmium is an inducer of oxidative stress in yeast

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 356, Issue 2, 1996, Pages 171-178

  Brennan, Richard J ^a   Schiestl, Robert H ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cadmium; DEL recombination; Free radical; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; CADMIUM; CADMIUM SULFATE; FREE RADICAL;

ARTICLE; GENOTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; YEAST;

EID: 0030599134     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(96)00051-6     Document Type: Article

References (40)

1. Ames B.N. (1989) Endogenous DNA damage as related to cancer and aging, Mutation Res., 250, 3-16.
2. Ames, B.N. and L.S. Gold (1990a) Chemical carcinogenesis: too many rodent carcinogens, Proc. Natl. Acad. Sci. USA, 87, 7772-7776.
3. Ames, B.N. and L.S. Gold (1990b) Too many rodent carcinogens: mitogenesis increases mutagenesis, Science, 249, 970-971.
4. Ames B.N. and L.S. Gold (1991) Endogenous mutagens and the causes of aging and cancer, Mutation Res., 214, 41-46.
5. Aruoma, O.I., B. Halliwell, B.M. Hoey and J. Butler (1989) The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid, Free Radical Biol. Med., 6, 593-597.
6. Athar, M., H. Mukhtar, D.R. Bickers, I.U. Khan and B. Kalyanaraman (1989) Evidence for the metabolism of tumor promoter organic hydroperoxides into free radicals by human carcinoma skin keratinocytes: an ESR-spin trapping study, Carcinogenesis, 10, 1499-1503.
7. Aubrecht, J.A., R.R. Rugo and R.H. Schiestl (1995) Carcinogens induce intrachromosomal recombination in human cells, Carcinogenesis, 16, 2841-2846.
8. Brennan, R.J., B.E.P. Swoboda and R.H. Schiestl (1994) Oxidative mutagens induce intrachromosomal recombination in yeast, Mutation Res., 308, 159-167.
9. Butterworth, E.B. and T.J. Slaga (1987) Nongenotoxic mechanisms in carcinogenesis, 25th Banbury Report, Cold Spring Harbour Laborartory, Cold Spring Harbour, NY.
10. Carls, N., and R.H. Schiestl (1994) Evaluation of the yeast DEL assay with ten compounds selected by the International Program on Chemical Safety for the evaluation of short-term tests for carcinogens, Mutation Res., 320, 293-303.
11. Chubatsu, L.S., M. Gennari and R. Meneghini (1992) Glutathione is the antioxidant responsible for resistance to oxidative stress in V79 Chinese hamster fibroblasts rendered resistant to cadmium, Chemico-Biological Interactions, 82, 99-110.
12. Clayson, D.B. (1989) International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC publication No. 17. Can a mechanistic rationale be provided for non-genotoxic carcinogens identified in rodent bioassays? Mutation Res., 221, 53-67.
13. Galli, A. and R.H. Schiestl (1995) Salmonella test positive and negative carcinogens show different effects on intrachromosomal recombination in G2 arrested cells, Carcinogenesis, 16, 659-663.
14. Gralla, E.B. and J.S. Valentine (1991) Null mutants of Saccharomyces cerevisiae Cu, Zn superoxide dismutase: characterisation and spontaneous mutation rates, J. Bacteriol., 173, 5918-5920.
15. Grasso, P., M. Sharratt and A.J. Cohen (1991) Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans, Annu. Rev. Pharmacol. Toxicol., 31, 253-287.
16. Hart, B.A., G.W. Voss, M.A. Shatos, and J. Doherty (1990) Cross-tolerance to hyperoxia following cadmium aerosol pretreatment, Toxicol. Appl. Pharmacol., 103, 255-270.
17. IARC Monographs on the evaluation of carcinogenic risks to humans (1987) Suppl. 7, IARC, Lyon.
18. Imlay, J.A. and S. Linn (1988) DNA damage and oxygen radical toxicity, Science, 240, 1302-2976.
19. Joenje, H., M.V.M. Lafleur and J. Retèl (1991) in: Vigo-Pelfry, C (Ed.), Membrane and lipid oxidation, vol. 3, CRC Press, Boca Raton, FL, pp. 87-113.
20. Kang, Y.J. (1992) Exogenous glutathione decreases cellular cadmium uptake and toxicity, Drug Metabolism and Disposition, 20, 714-718.
21. Koizumi, T., Z.G. Li and H. Tatsumoto (1992) DNA damaging activity of cadmium in Leydig cells, a target cell population for cadmium carcinogenesis in the rat testis, Toxicol. Lett., 63, 211-220.
22. Lindroos, P., R. Zarnegar and G.K. Michalopoulos (1991) Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration, Hepatology, 13, 743-750.
23. Malkin, D., F.P. Li, L.C. Strong, J.F. Fraumeni Jr., C.E. Nelson, D.H. Kim, J. Kassel, M.A. Gryka, F.Z. Bischoff, M.A. Tainsky and S.H. Friend (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms, Science, 250, 1233-1238.
24. Meyn, M.S. (1993) High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia, Science, 260, 1327-1330.
25. Müller, T., R. Schuckelt and L. Jaenicke (1994) Cadmium/zinc-metallothionein induces DNA strand breaks in vitro, Environ. Health Perspectives, 102 (Suppl. 3), 27-29.
26. NTP 1991: Sixth annual report on carcinogens, summary 1991, U.S. Department of Health and Human Services.
27. Ochi, T., K. Takahashi, and M. Ohsawa (1987) Indirect evidence for the induction of a prooxidant state by cadmium chloride in cultured mammalian cells and a possible mechanism for the induction, Mutation Res., 180, 257-266.
28. Ohtake, Y. and S. Yabuuchi (1991) Molecular cloning of the gamma-glutamylcysteine synthetase gene of Saccharomyces cerevisiae, Yeast, 7, 953-961.
29. Ramel, C. (1990) in: A. Kappas (Ed.), Mechanisms of Environmental Mutagenesis-Carcinogenesis, Plenum Press, New York, pp. 1-3.
30. Rossman, T.G., N/K. Roy, and W.C. Lin (1992) Is cadmium genotoxic? IARC Sci. Publ., 118, 367-375.
31. 2 in cultured endothelial cells, Arch. Biochem. Biophys., 302, 348-355.
32. Saul, R.L. and B.N. Ames (1986) Background levels of DNA damage in the population, in: M. Simic and L. Grossman (Eds.), Mechanism of DNA Damage and Repair, Plenum Press, New York.
33. Schiestl, R.H. (1989) Non-mutagenic carcinogens induce intrachromosomal recombination in yeast, Nature (Lond.) 337, 285-288.
34. Schiestl R.H., R.D. Gietz, R.D. Mehta and P.J. Hastings (1989), Carcinogens induce intrachromosomal recombination in yeast, Carcinogenesis 10, 1445-1455.
35. Schiestl R.H., F. Khogali and N. Carls (1994) Reversion of the mouse pink-eyed unstable mutation induced by low doses of x-rays, Science, 266, 1573-1576.
36. Shaw, I.C. and H.B. Jones (1994) Mechanisms of non-genotoxic carcinogenesis, Trends Pharm. Sci., 15, 89-93.
37. Sinha, B.H. (1983) Enzymatic activation of hydrazine derivatives. A spin-trapping study, J. Biol. Chem., 258, 796-801.
38. Tennant, R.W., B.H. Margolin, M.D. Shelby, E. Zeiger, J.K. Haseman, J. Spalding, W. Caspsry, M. Resnick, S. Stasiewicz, B. Anderson and R. Minor (1987) Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays, Science, 236, 933-941.
39. Yurkow, E.J. and M.A. McKenzie (1993) Characterization of hypoxia-dependent peroxide production in cultures of Saccharomyces cerevisiae using flow cytometry: a model for ischemic tissue destruction, Cytometry, 14, 287-293.
40. Zhang, L.-H. and D. Jenssen (1992) Reversion of the hprt mutant clone SP5 by intrachromosomal recombination, Carcinogenesis, 13, 609-615.