Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 5, 2008, Pages 1016-1029

  Dilda, Pierre J ^a   Perrone, Gabriel G ^a   Philp, Amanda ^b   Lock, Richard B ^b   Dawes, Ian W ^a   Hogg, Philip J ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

Author keywords

Acute promyelocytic leukemia; Arsenic trioxide; Osmoregulation; Yeast

Indexed keywords

ARSENIC TRIOXIDE; ARSENITE SODIUM; GLYCEROL; METAL;

APOPTOSIS; ARTICLE; BACTERIAL STRAIN; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; GLYCEROL BLOOD LEVEL; IC 50; LEUKEMIA CELL; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOREGULATION; OSMOTIC STRESS; PROMYELOCYTIC LEUKEMIA; SACCHAROMYCES CEREVISIAE; SENSITIVITY ANALYSIS; WILD TYPE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENICALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CYTOSKELETAL PROTEINS; DNA REPAIR; GENE DELETION; GLUTATHIONE; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; OSMOTIC PRESSURE; OXIDATIVE STRESS; OXIDES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; VACUOLES;

SACCHAROMYCES CEREVISIAE;

EID: 40149097447     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.11.002     Document Type: Article

References (52)

1. Alvarez P., Smith A., Fleming J., and Solomon F. Modulation of tubulin polypeptide ratios by the yeast protein Pac10p. Genetics 149 (1998) 857-864
2. Aono J., Yanagawa T., Itoh K., Li B., Yoshida H., Kumagai Y., et al. Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochemical and Biophysical Research Communications 305 (2003) 271-277
3. 2 and thiol-reactive chemicals signaling. Free Radical Biology and Medicine 35 (2003) 889-900
4. Barbour L., and Xiao W. Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: A yeast model. Mutation Research 532 (2003) 137-155
5. Bhattacharjee H., Carbrey J., Rosen B.P., and Mukhopadhyay R. Drug uptake and pharmacological modulation of drug sensitivity in leukemia by AQP9. Biochemical and Biophysical Research Communications 322 (2004) 836-841
6. Borggrefe T., Davis R., Erdjument-Bromage H., Tempst P., and Kornberg R.D. A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast. Journal of Biological Chemistry 277 (2002) 44202-44207
7. Dai J., Weinberg R.S., Waxman S., and Jing Y. Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system. Blood 93 (1999) 268-277
8. Danaee H., Nelson H.H., Liber H., Little J.B., and Kelsey K.T. Low dose exposure to sodium arsenite synergistically interacts with UV radiation to induce mutations and alter DNA repair in human cells. Mutagenesis 19 (2004) 143-148
9. Dilda P.J., Don A.S., Tanabe K.M., Higgins V.J., Allen J.D., Dawes I.W., et al. Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. Journal of the National Cancer Institute 97 (2005) 1539-1547
10. Dong J.T., and Luo X.M. Effects of arsenic on DNA damage and repair in human fetal lung fibroblasts. Mutation Research 315 (1994) 11-15
11. Donoghue N., Yam P.T., Jiang X.M., and Hogg P.J. Presence of closely spaced protein thiols on the surface of mammalian cells. Protein Science 9 (2000) 2436-2445
12. Gazitt Y., and Akay C. Arsenic trioxide: An anti cancer missile with multiple warheads. Hematology 10 (2005) 205-213
13. Ghosh M., Shen J., and Rosen B.P. Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 96 (1999) 5001-5006
14. Grad J.M., Bahlis N.J., Reis I., Oshiro M.M., Dalton W.S., and Boise L.H. Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells. Blood 98 (2001) 805-813
15. Haugen A.C., Kelley R., Collins J.B., Tucker C.J., Deng C., Afshari C.A., et al. Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biology 5 (2004) R95
16. Higgins V.J., Beckhouse A.G., Oliver A.D., Rogers P.J., and Dawes I.W. Yeast genome-wide expression analysis identifies a strong ergosterol and oxidative stress response during the initial stages of an industrial lager fermentation. Applied and Environmental Microbiology 69 (2003) 4777-4787
17. Hohmann S. Osmotic stress signaling and osmoadaptation in yeasts. Microbiology and Molecular Biology Reviews 66 (2002) 300-372
18. Hughes M.F. Arsenic toxicity and potential mechanisms of action. Toxicology Letters 133 (2002) 1-16
19. Juhnke H., Krems B., Kotter P., and Entian K.D. Mutants that show increased sensitivity to hydrogen peroxide reveal an important role for the pentose phosphate pathway in protection of yeast against oxidative stress. Molecular Genetics 252 (1996) 456-464
20. Jungmann J., Reins H.A., Lee J., Romeo A., Hassett R., Kosman D., et al. MAC1, a nuclear regulatory protein related to Cu-dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast. The EMBO Journal 12 (1993) 5051-5056
21. Kamath-Loeb A.S., Loeb L.A., Johansson E., Burgers P.M., and Fry M. Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence. Journal of Biological Chemistry 276 (2001) 16439-16446
22. Kim Y.J., Bjorklund S., Li Y., Sayre M.H., and Kornberg R.D. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77 (1994) 599-608
23. Kirkpatrick D.S., Dale K.V., Catania J.M., and Gandolfi A.J. Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells. Toxicology and Applied Pharmacology 186 (2003) 101-109
24. Kramer G.C. Hypertonic resuscitation: Physiologic mechanisms and recommendations for trauma care. Journal of Trauma 54 (2003) S89-S99
25. Lee K.H., Chang M.Y., Ahn J.I., Yu D.H., Jung S.S., Choi J.H., et al. Differential gene expression in retinoic acid-induced differentiation of acute promyelocytic leukemia cells, NB4 and HL-60 cells. Biochemical and Biophysical Research Communications 296 (2002) 1125-1133
26. Leung J., Pang A., Yuen W.H., Kwong Y.L., and Tse E.W. Relationship of expression of aquaglyceroporin 9 with arsenic uptake and sensitivity in leukemia cells. Blood 109 (2007) 740-746
27. Li J., Gorospe M., Barnes J., and Liu Y. Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts. Journal of Biological Chemistry 278 (2003) 13183-13191
28. Li J.H., and Rossman T.G. Inhibition of DNA ligase activity by arsenite: A possible mechanism of its comutagenesis. Molecular Toxicology 2 (1989) 1-9
29. Li Z.S., Szczypka M., Lu Y.P., Thiele D.J., and Rea P.A. The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. Journal of Biological Chemistry 271 (1996) 6509-6517
30. Liu Z., Shen J., Carbrey J.M., Mukhopadhyay R., Agre P., and Rosen B.P. Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proceedings of the National Academy of Sciences of the United States of America, 99 (2002) 6053-6058
31. Miller Jr. W.H., Schipper H.M., Lee J.S., Singer J., and Waxman S. Mechanisms of action of arsenic trioxide. Cancer Research 62 (2002) 3893-3903
32. Pelicano H., Feng L., Zhou Y., Carew J.S., Hileman E.O., Plunkett W., et al. Inhibition of mitochondrial respiration: A novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. Journal of Biological Chemistry 278 (2003) 37832-37839
33. Ramirez P., Eastmond D.A., Laclette J.P., and Ostrosky-Wegman P. Disruption of microtubule assembly and spindle formation as a mechanism for the induction of aneuploid cells by sodium arsenite and vanadium pentoxide. Mutation Research 386 (1997) 291-298
34. Reiter A., Lengfelder E., and Grimwade D. Pathogenesis, diagnosis and monitoring of residual disease in acute promyelocytic leukaemia. Acta Haematologica 112 (2004) 55-67
35. Rep M., Proft M., Remize F., Tamas M., Serrano R., Thevelein J.M., et al. The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage. Molecular Microbiology 40 (2001) 1067-1083
36. Robinson M.D., Grigull J., Mohammad N., and Hughes T.R. FunSpec: A web-based cluster interpreter for yeast. BMC Bioinformatics 3 (2002) 35
37. Schaerer F., Morgan G., Winey M., and Philippsen P. Cnm67p is a spacer protein of the Saccharomyces cerevisiae spindle pole body outer plaque. Molecular Biology of the Cell 12 (2001) 2519-2533
38. Sheikh-Hamad D., and Gustin M.C. MAP kinases and the adaptive response to hypertonicity: Functional preservation from yeast to mammals. American Journal of Physiology. Renal Physiology 287 (2004) F1102-F1110
39. 3. International Journal of Molecular Medicine 11 (2003) 479-484
40. Sturtz L.A., Diekert K., Jensen L.T., Lill R., and Culotta V.C. A fraction of yeast Cu,Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage. Journal of Biological Chemistry 276 (2001) 38084-38089
41. Tamas M.J., Karlgren S., Bill R.M., Hedfalk K., Allegri L., Ferreira M., et al. A short regulatory domain restricts glycerol transport through yeast Fps1p. Journal of Biological Chemistry 278 (2003) 6337-6345
42. Tamas M.J., Rep M., Thevelein J.M., and Hohmann S. Stimulation of the yeast high osmolarity glycerol (HOG) pathway: Evidence for a signal generated by a change in turgor rather than by water stress. FEBS Letters 472 (2000) 159-165
43. Thorsen M., Di Y., Tangemo C., Morillas M., Ahmadpour D., Van der Does C., et al. The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast. Molecular Biology of the Cell 17 (2006) 4400-4410
44. Tong A.H., Lesage G., Bader G.D., Ding H., Xu H., Xin X., et al. Global mapping of the yeast genetic interaction network. Science 303 (2004) 808-813
45. Trigon S., and Morange M. Different carboxyl-terminal domain kinase activities are induced by heat-shock and arsenite. Characterization of their substrate specificity, separation by Mono Q chromatography, and comparison with the mitogen-activated protein kinases. Journal of Biological Chemistry 270 (1995) 13091-13098
46. Tsukaguchi H., Weremowicz S., Morton C.C., and Hediger M.A. Functional and molecular characterization of the human neutral solute channel aquaporin-9. American Journal of Physiology 277 (1999) F685-F696
47. Umenishi F., and Schrier R.W. Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene. Journal of Biological Chemistry 278 (2003) 15765-15770
48. van Duin M., van den Tol J., Warmerdam P., Odijk H., Meijer D., Westerveld A., et al. Evolution and mutagenesis of the mammalian excision repair gene ERCC-1. Nucleic Acids Research 16 (1988) 5305-5322
49. Winzeler E.A., Shoemaker D.D., Astromoff A., Liang H., Anderson K., Andre B., et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285 (1999) 901-906
50. Wysocki R., Bobrowicz P., and Ulaszewski S. The Saccharomyces cerevisiae ACR3 gene encodes a putative membrane protein involved in arsenite transport. Journal of Biological Chemistry 272 (1997) 30061-30066
51. Yang C.H., Kuo M.L., Chen J.C., and Chen Y.C. Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells. British Journal of Cancer 81 (1999) 796-799
52. Zhou X., Yoshida K., Kuroda K., Endo Y., and Endo G. Effects of cysteine on the cytotoxicity of arsenic compounds. Archives of Environmental Contamination and Toxicology 45 (2003) 324-330